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Experiments

Compound Investigated event Experiment type Concentration Cell line Organism Animal model Stat protein Details
BP-1-102/ 17o Supression of tumor supporting factors Western Blot 15.00 µM MDA-MB-231 Homo sapiens
BP-1-102/ 17o Supression of tumor supporting factors Western Blot 10.00 µM MDA-MB-231 Homo sapiens
BP-1-102/ 17o Supression of tumor supporting factors Western Blot 15.00 µM MDA-MB-231 Homo sapiens
BP-1-102/ 17o Supression of tumor supporting factors Western Blot 10.00 µM MDA-MB-231 Homo sapiens
BP-1-102/ 17o Supression of tumor supporting factors Western Blot 15.00 µM MDA-MB-231 Homo sapiens
BP-1-102/ 17o Supression of tumor supporting factors Western Blot 15.00 µM MDA-MB-231 Homo sapiens
BP-1-102/ 17o Supression of tumor supporting factors Western Blot 15.00 µM MDA-MB-231 Homo sapiens
BP-1-102/ 17o Supression of tumor supporting factors in cells transfected with control or Stat3 siRNA Western Blot 15.00 µM MDA-MB-231 Homo sapiens
BP-1-102/ 17o Supression of tumor supporting factors in cells transfected with control or Stat3 siRNA Western Blot 15.00 µM MDA-MB-231 Homo sapiens
BP-1-102/ 17o Supression of tumor supporting factors in cells transfected with control or Stat3 siRNA Western Blot 15.00 µM MDA-MB-231 Homo sapiens
BP-1-102/ 17o in cells overexpressing KLF8 BioCoat invasion chamber assay 10.00 µM MDA-MB-231 Homo sapiens
BP-1-102/ 17o in cells overexpressing KLF8 BioCoat invasion chamber assay 5.00 µM MDA-MB-231 Homo sapiens
BP-1-102/ 17o Immunoblotting analysis (whole cell- WC; cytoplasmic- Cyto; nuclear- Nuc) Western Blot- WC 15.00 µM MDA-MB-231 Homo sapiens p-STAT3
BP-1-102/ 17o Immunoblotting analysis (whole cell- WC; cytoplasmic- Cyto; nuclear- Nuc) Western Blot- WC 15.00 µM MDA-MB-231 Homo sapiens STAT3
BP-1-102/ 17o Immunoblotting analysis (whole cell- WC; cytoplasmic- Cyto; nuclear- Nuc) Western Blot- WC 15.00 µM MDA-MB-231 Homo sapiens
BP-1-102/ 17o Immunoblotting analysis (whole cell- WC; cytoplasmic- Cyto; nuclear- Nuc) Western Blot- WC 15.00 µM MDA-MB-231 Homo sapiens
BP-1-102/ 17o Immunoblotting analysis (whole cell- WC; cytoplasmic- Cyto; nuclear- Nuc) Western Blot- WC 15.00 µM MDA-MB-231 Homo sapiens
BP-1-102/ 17o Immunoblotting analysis (whole cell- WC; cytoplasmic- Cyto; nuclear- Nuc) Western Blot- Cyto 15.00 µM MDA-MB-231 Homo sapiens p-STAT3
BP-1-102/ 17o Immunoblotting analysis (whole cell- WC; cytoplasmic- Cyto; nuclear- Nuc) Western Blot- Cyto 15.00 µM MDA-MB-231 Homo sapiens STAT3
BP-1-102/ 17o Immunoblotting analysis (whole cell- WC; cytoplasmic- Cyto; nuclear- Nuc) Western Blot- Cyto 15.00 µM MDA-MB-231 Homo sapiens
BP-1-102/ 17o Immunoblotting analysis (whole cell- WC; cytoplasmic- Cyto; nuclear- Nuc) Western Blot- Cyto 15.00 µM MDA-MB-231 Homo sapiens
BP-1-102/ 17o Immunoblotting analysis (whole cell- WC; cytoplasmic- Cyto; nuclear- Nuc) Western Blot- Cyto 15.00 µM MDA-MB-231 Homo sapiens
BP-1-102/ 17o Immunoblotting analysis (whole cell- WC; cytoplasmic- Cyto; nuclear- Nuc) Western Blot- Nuc 15.00 µM MDA-MB-231 Homo sapiens p-STAT3
BP-1-102/ 17o Immunoblotting analysis (whole cell- WC; cytoplasmic- Cyto; nuclear- Nuc) Western Blot- Nuc 15.00 µM MDA-MB-231 Homo sapiens STAT3
BP-1-102/ 17o Immunoblotting analysis (whole cell- WC; cytoplasmic- Cyto; nuclear- Nuc) Western Blot- Nuc 15.00 µM MDA-MB-231 Homo sapiens
BP-1-102/ 17o Immunoblotting analysis (whole cell- WC; cytoplasmic- Cyto; nuclear- Nuc) Western Blot- Nuc 15.00 µM MDA-MB-231 Homo sapiens
BP-1-102/ 17o Immunoblotting analysis (whole cell- WC; cytoplasmic- Cyto; nuclear- Nuc) Western Blot- Nuc 15.00 µM MDA-MB-231 Homo sapiens
BP-1-102/ 17o Influence on cell viability and proliferation CyQUANT cell proliferation assay 10.00 µM 231 Homo sapiens
BP-1-102/ 17o Influence on cell viability and proliferation CyQUANT cell proliferation assay 20.00 µM 231 Homo sapiens
BP-1-102/ 17o Influence on cell viability and proliferation CyQUANT cell proliferation assay 30.00 µM 231 Homo sapiens
BP-1-102/ 17o Influence on cell migration Wound healing assay 10.00 µM 231 Homo sapiens
BP-1-102/ 17o Influence on cell migration Wound healing assay 15.00 µM 231 Homo sapiens
BP-1-102/ 17o Influence on cell viability and proliferation CyQUANT cell proliferation assay 10.00 µM 231/St3C Homo sapiens
BP-1-102/ 17o Influence on cell viability and proliferation CyQUANT cell proliferation assay 20.00 µM 231/St3C Homo sapiens
BP-1-102/ 17o Influence on cell viability and proliferation CyQUANT cell proliferation assay 30.00 µM 231/St3C Homo sapiens
BP-1-102/ 17o Antitumor effect Tumor size 1.00 mg/kg MDA-MB-231 (xenograft) Mus musculus
BP-1-102/ 17o Antitumor effect Tumor size 3.00 mg/kg MDA-MB-231 (xenograft) Mus musculus