Investigated event: Supression of tumor supporting factors in cells transfected with control or Stat3 siRNA

Name Value
Compound BP-1-102/ 17o
Investigated event Supression of tumor supporting factors in cells transfected with control or Stat3 siRNA
Experiment type Western Blot
Concentration 15.00 µM
Cell line MDA-MB-231
Organism Homo sapiens
Animal model
STAT protein
Other EPSTI1
Reference
Orally bioavailable small-molecule inhibitor of transcription factor Stat3 regresses human breast and lung cancer xenografts. Proceedings of the National Academy of Sciences of the United States of America Xiaolei Zhang, Peibin Yue, Brent D G Page, Tianshu Li, Wei Zhao, Andrew T Namanja, David Paladino, Jihe Zhao, Yuan Chen, Patrick T Gunning, James Turkson, 109, 24, 2012-06-12, 2012-05-23, 10.1073/pnas.1121606109 DOI: 10.1073/pnas.1121606109 PUBMED: 22623533 PMCID: PMC3386073