Investigated event: in cells overexpressing KLF8

Name Value
Compound BP-1-102/ 17o
Investigated event in cells overexpressing KLF8
Experiment type BioCoat invasion chamber assay
Concentration 5.00 µM
Cell line MDA-MB-231
Organism Homo sapiens
Animal model
STAT protein
Other
Reference
Orally bioavailable small-molecule inhibitor of transcription factor Stat3 regresses human breast and lung cancer xenografts. Proceedings of the National Academy of Sciences of the United States of America Xiaolei Zhang, Peibin Yue, Brent D G Page, Tianshu Li, Wei Zhao, Andrew T Namanja, David Paladino, Jihe Zhao, Yuan Chen, Patrick T Gunning, James Turkson, 109, 24, 2012-06-12, 2012-05-23, 10.1073/pnas.1121606109 DOI: 10.1073/pnas.1121606109 PUBMED: 22623533 PMCID: PMC3386073