Investigated event: Influence on cell viability and proliferation

Name Value
Compound BP-1-102/ 17o
Investigated event Influence on cell viability and proliferation
Experiment type CyQUANT cell proliferation assay
Concentration 20.00 µM
Cell line 231/St3C
Organism Homo sapiens
Animal model
STAT protein
Other
Reference
Orally bioavailable small-molecule inhibitor of transcription factor Stat3 regresses human breast and lung cancer xenografts. Proceedings of the National Academy of Sciences of the United States of America Xiaolei Zhang, Peibin Yue, Brent D G Page, Tianshu Li, Wei Zhao, Andrew T Namanja, David Paladino, Jihe Zhao, Yuan Chen, Patrick T Gunning, James Turkson, 109, 24, 2012-06-12, 2012-05-23, 10.1073/pnas.1121606109 DOI: 10.1073/pnas.1121606109 PUBMED: 22623533 PMCID: PMC3386073