Investigated event: Antitumor effect

Name Value
Compound BP-1-102/ 17o
Investigated event Antitumor effect
Experiment type Tumor size
Concentration 3.00 mg/kg
Cell line MDA-MB-231 (xenograft)
Organism Mus musculus
Animal model
STAT protein
Other
Reference
Orally bioavailable small-molecule inhibitor of transcription factor Stat3 regresses human breast and lung cancer xenografts. Proceedings of the National Academy of Sciences of the United States of America Xiaolei Zhang, Peibin Yue, Brent D G Page, Tianshu Li, Wei Zhao, Andrew T Namanja, David Paladino, Jihe Zhao, Yuan Chen, Patrick T Gunning, James Turkson, 109, 24, 2012-06-12, 2012-05-23, 10.1073/pnas.1121606109 DOI: 10.1073/pnas.1121606109 PUBMED: 22623533 PMCID: PMC3386073