| SAR317461 |
Influence on protein activity |
Western Blot |
0.10 µM |
GBM4 |
Homo sapiens |
|
p-STAT5 |
|
| SAR317461 |
Influence on protein activity |
Western Blot |
2.00 µM |
GBM4 |
Homo sapiens |
|
p-STAT5 |
|
| SAR317461 |
Influence on protein activity |
Western Blot |
10.00 µM |
GBM4 |
Homo sapiens |
|
p-STAT5 |
|
| SAR317461 |
Influence on protein activity |
Western Blot |
0.10 µM |
GBM8 |
Homo sapiens |
|
p-STAT5 |
|
| SAR317461 |
Influence on protein activity |
Western Blot |
2.00 µM |
GBM8 |
Homo sapiens |
|
p-STAT5 |
|
| SAR317461 |
Influence on protein activity |
Western Blot |
10.00 µM |
GBM8 |
Homo sapiens |
|
p-STAT5 |
|
| SAR317461 |
Influence on protein activity |
Western Blot |
0.10 µM |
GBM4 |
Homo sapiens |
|
STAT5 |
|
| SAR317461 |
Influence on protein activity |
Western Blot |
2.00 µM |
GBM4 |
Homo sapiens |
|
STAT5 |
|
| SAR317461 |
Influence on protein activity |
Western Blot |
10.00 µM |
GBM4 |
Homo sapiens |
|
STAT5 |
|
| SAR317461 |
Influence on protein activity |
Western Blot |
0.10 µM |
GBM8 |
Homo sapiens |
|
STAT5 |
|
| SAR317461 |
Influence on protein activity |
Western Blot |
2.00 µM |
GBM8 |
Homo sapiens |
|
STAT5 |
|
| SAR317461 |
Influence on protein activity |
Western Blot |
10.00 µM |
GBM8 |
Homo sapiens |
|
STAT5 |
|
| SAR317461 |
Influence on protein activity |
Western Blot |
0.10 µM |
GBM4 |
Homo sapiens |
|
|
|
| SAR317461 |
Influence on protein activity |
Western Blot |
2.00 µM |
GBM4 |
Homo sapiens |
|
|
|
| SAR317461 |
Influence on protein activity |
Western Blot |
10.00 µM |
GBM4 |
Homo sapiens |
|
|
|
| SAR317461 |
Influence on protein activity |
Western Blot |
0.10 µM |
GBM8 |
Homo sapiens |
|
|
|
| SAR317461 |
Influence on protein activity |
Western Blot |
2.00 µM |
GBM8 |
Homo sapiens |
|
|
|
| SAR317461 |
Influence on protein activity |
Western Blot |
10.00 µM |
GBM8 |
Homo sapiens |
|
|
|
| SAR317461 |
Influence on protein activity |
Western Blot |
0.10 µM |
GBM4 |
Homo sapiens |
|
|
|
| SAR317461 |
Influence on protein activity |
Western Blot |
2.00 µM |
GBM4 |
Homo sapiens |
|
|
|
| SAR317461 |
Influence on protein activity |
Western Blot |
10.00 µM |
GBM4 |
Homo sapiens |
|
|
|
| SAR317461 |
Influence on protein activity |
Western Blot |
0.10 µM |
GBM8 |
Homo sapiens |
|
|
|
| SAR317461 |
Influence on protein activity |
Western Blot |
2.00 µM |
GBM8 |
Homo sapiens |
|
|
|
| SAR317461 |
Influence on protein activity |
Western Blot |
10.00 µM |
GBM8 |
Homo sapiens |
|
|
|
| SAR317461 |
Influence on protein activity |
Western Blot |
0.10 µM |
GBM4 |
Homo sapiens |
|
|
|
| SAR317461 |
Influence on protein activity |
Western Blot |
2.00 µM |
GBM4 |
Homo sapiens |
|
|
|
| SAR317461 |
Influence on protein activity |
Western Blot |
10.00 µM |
GBM4 |
Homo sapiens |
|
|
|
| SAR317461 |
Influence on protein activity |
Western Blot |
0.10 µM |
GBM8 |
Homo sapiens |
|
|
|
| SAR317461 |
Influence on protein activity |
Western Blot |
2.00 µM |
GBM8 |
Homo sapiens |
|
|
|
| SAR317461 |
Influence on protein activity |
Western Blot |
10.00 µM |
GBM8 |
Homo sapiens |
|
|
|
| SAR317461 |
Influence on cell apoptosis |
Flow cytometry- annexin V binding and propidium iodide staining |
2.00 µM |
GBM8 |
Homo sapiens |
|
|
|
| SAR317461 |
Influence on cell apoptosis |
Flow cytometry- annexin V binding and propidium iodide staining |
2.00 µM |
GBM4 |
Homo sapiens |
|
|
|
| AS1810722 |
Influence on hepatic metabolism |
LC-MS; HPLC |
5.00 µM |
HLM |
Homo sapiens |
|
|
|
| AS1810722 |
Influence on cell differentiation |
ELISA |
0.10 nM |
Th1 |
Mus musculus |
c57BL/6 |
|
|
| AS1810722 |
Influence on cell differentiation |
ELISA |
0.10 nM |
Th2 |
Mus musculus |
c57BL/6 |
|
|
| AS1810722 |
Influence on cell differentiation |
ELISA |
1.00 nM |
Th1 |
Mus musculus |
c57BL/6 |
|
|
| AS1810722 |
Influence on cell differentiation |
ELISA |
1.00 nM |
Th2 |
Mus musculus |
c57BL/6 |
|
|
| AS1810722 |
Influence on cell differentiation |
ELISA |
10.00 nM |
Th1 |
Mus musculus |
c57BL/6 |
|
|
| AS1810722 |
Influence on cell differentiation |
ELISA |
10.00 nM |
Th2 |
Mus musculus |
c57BL/6 |
|
|
| AS1810722 |
Influence on eosinophils accumulation in BALF |
Differential cell count |
0.03 mg/kg |
eosinophil |
Mus musculus |
BALB/c |
|
|
| AS1810722 |
Influence on eosinophils accumulation in BALF |
Differential cell count |
0.10 mg/kg |
eosinophil |
Mus musculus |
BALB/c |
|
|
| AS1810722 |
Influence on eosinophils accumulation in BALF |
Differential cell count |
0.30 mg/kg |
eosinophil |
Mus musculus |
BALB/c |
|
|
| Cyclometalated rhodium(III) complex 12 |
Influence on tumor growth |
Average tumor volume |
75.00 mg/kg |
A375(xenograft) |
Mus musculus |
BALB/c |
|
|
| Cyclometalated rhodium(III) complex 12 |
Influence on tumor growth |
Average body weight |
75.00 mg/kg |
A375(xenograft) |
Mus musculus |
BALB/c |
|
|
| Cyclometalated rhodium(III) complex 12 |
Influence on tumor growth |
Mean tumor weight |
75.00 mg/kg |
A375(xenograft) |
Mus musculus |
BALB/c |
|
|
| Cyclometalated rhodium(III) complex 12 |
Influence on tumor growth |
Mean organ weight |
75.00 mg/kg |
A375(xenograft) |
Mus musculus |
BALB/c |
|
|
| Cyclometalated rhodium(III) complex 12 |
Influence on protein binding |
Cell-free assay |
0.30 µM |
A375 |
Homo sapiens |
|
|
|
| Cyclometalated rhodium(III) complex 12 |
Influence on protein binding |
Cell-free assay |
1.00 µM |
A375 |
Homo sapiens |
|
|
|
| Cyclometalated rhodium(III) complex 12 |
Influence on protein binding |
Cell-free assay |
3.00 µM |
A375 |
Homo sapiens |
|
|
|
| Cyclometalated rhodium(III) complex 12 |
Influence on protein binding |
Cell-free assay |
10.00 µM |
A375 |
Homo sapiens |
|
|
|
