| AG490 |
Influence on protein activity in presence of IL-6 |
Western Blot |
50.00 µM |
RT4 |
Homo sapiens |
|
p-STAT3 |
|
| AG490 |
Influence on protein activity in presence of IL-6 |
Western Blot |
50.00 µM |
RT4 |
Homo sapiens |
|
STAT3 |
|
| AG490 |
Influence on protein activity in presence of IL-6 |
Western Blot |
50.00 µM |
RT4 |
Homo sapiens |
|
|
|
| AG490 |
Influence on protein activity in presence of IL-6 |
Luciferase promoter assay |
50.00 µM |
RT4 |
Homo sapiens |
|
|
|
| AG490 |
Influence on protein activity in presence of IL-6 |
Western Blot |
50.00 µM |
RT4 |
Homo sapiens |
|
|
|
| AG490 |
Influence on protein activity in presence of IL-6 |
Western Blot |
50.00 µM |
RT4 |
Homo sapiens |
|
|
|
| AG490 |
Influence on protein activity |
Western Blot |
50.00 µM |
RT4 |
Homo sapiens |
|
|
|
| AG490 |
Influence on protein activity |
Western Blot |
50.00 µM |
RT4 |
Homo sapiens |
|
|
|
| AG490 |
Influence on protein activity |
Western Blot |
50.00 µM |
RT4 |
Homo sapiens |
|
|
|
| AG490 |
Influence on protein activity |
Western Blot |
50.00 µM |
RT4 |
Homo sapiens |
|
|
|
| AG490 |
Influence on protein activity |
Western Blot |
1.00 µM |
RT4 |
Homo sapiens |
|
|
|
| AG490 |
Influence on protein activity |
Western Blot |
5.00 µM |
RT4 |
Homo sapiens |
|
|
|
| AG490 |
Influence on protein activity |
Western Blot |
20.00 µM |
RT4 |
Homo sapiens |
|
|
|
| AG490 |
Influence on protein activity |
Western Blot |
100.00 µM |
RT4 |
Homo sapiens |
|
|
|
| AG490 |
Influence on protein activity |
Western Blot |
1.00 µM |
RT4 |
Homo sapiens |
|
|
|
| AG490 |
Influence on protein activity |
Western Blot |
5.00 µM |
RT4 |
Homo sapiens |
|
|
|
| AG490 |
Influence on protein activity |
Western Blot |
20.00 µM |
RT4 |
Homo sapiens |
|
|
|
| AG490 |
Influence on protein activity |
Western Blot |
100.00 µM |
RT4 |
Homo sapiens |
|
|
|
| AG490 |
Influence on gene expression levels |
RT-PCR |
50.00 µM |
RT4 |
Homo sapiens |
|
|
|
| AG490 |
Influence on gene expression levels |
RT-PCR |
50.00 µM |
RT4 |
Homo sapiens |
|
|
|
| AG490 |
Influence on protein degradation |
Western Blot |
50.00 µM |
RT4 |
Homo sapiens |
|
|
|
| AG490 |
Influence on protein activity in presence of protease inhibitors |
Western Blot |
50.00 µM |
RT4 |
Homo sapiens |
|
|
|
| AG490 |
Influence on protein activity in presence of protease inhibitors |
Western Blot |
50.00 µM |
RT4 |
Homo sapiens |
|
|
|
| AG490 |
Influence on protein synthesis |
Western Blot |
50.00 µM |
RT4 |
Homo sapiens |
|
|
|
| AG490 |
Influence on protein synthesis |
Western Blot |
50.00 µM |
RT4 |
Homo sapiens |
|
|
|
| AG490 |
Influence on protein activity |
Western Blot |
50.00 µM |
RT4 |
Homo sapiens |
|
|
|
| AG490 |
Influence on protein activity |
Western Blot |
50.00 µM |
RT4 |
Homo sapiens |
|
|
|
| AG490 |
Influene on protein activity in presence of ER stress inducer |
Western Blot |
50.00 µM |
RT4 |
Homo sapiens |
|
|
|
| AG490 |
Influene on protein activity in presence of ER stress inducer |
Western Blot |
50.00 µM |
RT4 |
Homo sapiens |
|
|
|
| AG490 |
Influene on protein activity in presence of ER stress inducer |
Western Blot |
50.00 µM |
RT4 |
Homo sapiens |
|
|
|
| AG490 |
Influence on correlation between proetin levels and IL-6 response |
Western Blot |
50.00 µM |
RT4 |
Homo sapiens |
|
|
|
| AG490 |
Influence on correlation between proetin levels and IL-6 response |
Western Blot |
50.00 µM |
RT4 |
Homo sapiens |
|
p-STAT3 |
|
| AG490 |
Influence on correlation between proetin levels and IL-6 response |
Western Blot |
50.00 µM |
RT4 |
Homo sapiens |
|
STAT3 |
|
| AG490 |
Influence on correlation between proetin levels and IL-6 response |
Western Blot |
50.00 µM |
RT4 |
Homo sapiens |
|
|
|
| AG490 |
Influence on protein activity in presence of IFNγ |
Western Blot |
10.00 µM |
1774 macrophages |
Homo sapiens |
|
STAT1α |
|
| AG490 |
Influence on protein activity in presence of IFNγ |
Western Blot |
100.00 µM |
1774 macrophages |
Homo sapiens |
|
STAT1α |
|
| AG490 |
Influence on nitric oxide (NO) generation |
Griess reaction |
3.00 µM |
1774 macrophages |
Homo sapiens |
|
|
|
| AG490 |
Influence on nitric oxide (NO) generation |
Griess reaction |
10.00 µM |
1774 macrophages |
Homo sapiens |
|
|
|
| AG490 |
Influence on nitric oxide (NO) generation |
Griess reaction |
30.00 µM |
1774 macrophages |
Homo sapiens |
|
|
|
| AG490 |
Influence on protein activity in presence of IFNγ |
Western Blot |
3.00 µM |
1774 macrophages |
Homo sapiens |
|
|
|
| AG490 |
Influence on protein activity in presence of IFNγ |
Western Blot |
10.00 µM |
1774 macrophages |
Homo sapiens |
|
|
|
| AG490 |
Influence on gene expression levels in presence of IFNγ |
RT-qPCR |
10.00 µM |
1774 macrophages |
Homo sapiens |
|
|
|
| AG490 |
Influence on gene expression levels in presence of IFNγ |
RT-qPCR |
10.00 µM |
1774 macrophages |
Homo sapiens |
|
|
|
| AG490 |
Influence on protein activity in presence of CLI and/or EPO |
Western Blot |
3.00 mg/kg |
quadriceps |
Rattus norvegicus |
Sprague-Dawley (SD) rats |
p-STAT1 |
|
| AG490 |
Influence on protein activity in presence of CLI and/or EPO |
Western Blot |
3.00 mg/kg |
quadriceps |
Rattus norvegicus |
Sprague-Dawley (SD) rats |
STAT1 |
|
| AG490 |
Influence on protein activity in presence of CLI and/or EPO |
Western Blot |
3.00 mg/kg |
quadriceps |
Rattus norvegicus |
Sprague-Dawley (SD) rats |
p-STAT3 |
|
| AG490 |
Influence on protein activity in presence of CLI and/or EPO |
Western Blot |
3.00 mg/kg |
quadriceps |
Rattus norvegicus |
Sprague-Dawley (SD) rats |
STAT3 |
|
| AG490 |
Influence on protein activity in presence of CLI and/or EPO |
Western Blot |
3.00 mg/kg |
quadriceps |
Rattus norvegicus |
Sprague-Dawley (SD) rats |
p-STAT5 |
|
| AG490 |
Influence on protein activity in presence of CLI and/or EPO |
Western Blot |
3.00 mg/kg |
quadriceps |
Rattus norvegicus |
Sprague-Dawley (SD) rats |
STAT5 |
|
| AG490 |
Influence on protein activity in presence of CLI and/or EPO |
Western Blot |
3.00 mg/kg |
quadriceps |
Rattus norvegicus |
Sprague-Dawley (SD) rats |
|
|
