STX-0119

Name Value
Weight 382.379 g/mol
Zinc ID ZINC4107278
Smiles O=C(Nc1nnc(-c2ccco2)o1)c1cc(-c2ccccc2)nc2ccccc12
Molecular formula C22H14N4O3
Mode of inhibition Direct STAT; Non-peptide small molecule
CAS 851095-32-4

Clinical Trials

Study title Status Conditions Link

Visualization

References

Publication DOI Pubmed PMCID
Antitumor activity of a novel small molecule STAT3 inhibitor against a human lymphoma cell line with high STAT3 activation. International journal of oncology Tadashi Ashizawa, Haruo Miyata, Hidee Ishii, Chie Oshita, Kenji Matsuno, Yoshiaki Masuda, Toshio Furuya, Tadashi Okawara, Masami Otsuka, Naohisa Ogo, Akira Asai, Yasuto Akiyama, 38, 5, None, 2011-02-28, 10.3892/ijo.2011.957 10.3892/ijo.2011.957 21369699 21369699
A sanitary survey of schools in Surat District. Indian journal of medical sciences B S Bhavsar, N R Mehta, 39, 3, None, None, 10.1021/ml1000273 10.1021/ml1000273 4007973 PMC4007973
Genome-Wide Inhibition of Pro-atherogenic Gene Expression by Multi-STAT Targeting Compounds as a Novel Treatment Strategy of CVDs. Frontiers in immunology Martyna Plens-Galaska, Malgorzata Szelag, Aida Collado, Patrice Marques, Susana Vallejo, Mariella Ramos-González, Joanna Wesoly, María Jesus Sanz, Concepción Peiró, Hans A R Bluyssen, 9, None, None, 2018-09-19, 10.3389/fimmu.2018.02141 10.3389/fimmu.2018.02141 30283459 PMC6156247

Vendors

Company Lnk to product
MERCK (Sigma Aldrich) https://www.merckmillipore.com/PL/pl/product/STAT3-Inhibitor-XI-STX-0119-Calbiochem,EMD_BIO-573126?ReferrerURL=https%3A%2F%2Fwww.google.com%2F&bd=1
Sigma Aldrich https://www.sigmaaldrich.com/catalog/product/mm/573126?lang=pl&region=PL
MedKoo Biosciences https://www.medkoo.com/products/6349
Glixxlabs http://glixxlabs.com/chemical-products/bioactive-screen-leads_p5/GLXC-03253
Key Organics https://www.keyorganics.net/stx-0119-mfcd04462306-851095-32-4-c22h14n4o3.html

Filter data

Compound STX-0119
Experiment types Adhesion assay, Body weight, Chromatin immunoprecipitation , Constriction assay , FRET, Flow cytometry , Hematoxylin and eosin staining , Immunostaining , Phosphorylation assay , RT-qPCR, Tumor volume, WST-1, Western Blot, Wound healing assay
Concentrations 10.00, 12.50, 160.00, 2.00, 20.00, 25.00, 36.00, 40.00, 5.00, 50.00, 6.25, 80.00, 9.00, N/A
Cell lines BC-3, CMK, HEK293, HH, HL-60, HMEC, HUT78, HUVECS, IM-9, Jurkat, K562, KG-1, MDA-MB-468, MOLT-3, NCI-H929, RPMI8226, SCC3, SCC3 (xenograft), TF-1, THP-1, U266B1, U937, mesenteric artery
Organisms Homo sapiens, Mus musculus
Animal models BALB/cA-nu/nu
STAT proteins STAT1, STAT2, STAT3, STAT3 (cytoplam), STAT3 (nucelus), STAT3-CFP, STAT3-YFP, p-STAT1, p-STAT2, p-STAT3, p-STAT3 (Y705), p-STAT3 (cytoplasm), p-STAT3 (nucleus)
Other Bcl-xL, CCL5, CXCL10, CXCL9, Cleaved Caspase-3, Cyclin D1, ICAM, IFIT2, IRF1, Ki67, OAS2, SOCS3, Survivin, VCAM, c-Myc, α-tubulin, β-actin

Experiments

Compound Experiment type Investigated event Concentration Cell line Organism Animal model Stat protein Details
STX-0119 WST-1 Influence on cell proliferation N/A µM IM-9 Homo sapiens
STX-0119 WST-1 Influence on cell proliferation N/A µM U937 Homo sapiens
STX-0119 WST-1 Influence on cell proliferation N/A µM Jurkat Homo sapiens
STX-0119 WST-1 Influence on cell proliferation N/A µM KG-1 Homo sapiens
STX-0119 WST-1 Influence on cell proliferation N/A µM MOLT-3 Homo sapiens
STX-0119 WST-1 Influence on cell proliferation N/A µM HL-60 Homo sapiens
STX-0119 WST-1 Influence on cell proliferation N/A µM THP-1 Homo sapiens
STX-0119 WST-1 Influence on cell proliferation N/A µM RPMI8226 Homo sapiens
STX-0119 WST-1 Influence on cell proliferation N/A µM SCC3 Homo sapiens
STX-0119 WST-1 Influence on cell proliferation N/A µM HUT78 Homo sapiens
STX-0119 WST-1 Influence on cell proliferation N/A µM HH Homo sapiens
STX-0119 WST-1 Influence on cell proliferation N/A µM K562 Homo sapiens
STX-0119 WST-1 Influence on cell proliferation N/A µM CMK Homo sapiens
STX-0119 WST-1 Influence on cell proliferation N/A µM BC-3 Homo sapiens
STX-0119 WST-1 Influence on cell proliferation N/A µM U266B1 Homo sapiens
STX-0119 WST-1 Influence on cell proliferation N/A µM NCI-H929 Homo sapiens
STX-0119 WST-1 Influence on cell proliferation N/A µM TF-1 Homo sapiens
STX-0119 Phosphorylation assay Influence on protein activity 5.00 µM SCC3 Homo sapiens p-STAT3
STX-0119 Phosphorylation assay Influence on protein activity 20.00 µM SCC3 Homo sapiens p-STAT3
STX-0119 Phosphorylation assay Influence on protein activity 9.00 µM U937 Homo sapiens p-STAT3
STX-0119 Phosphorylation assay Influence on protein activity 36.00 µM U937 Homo sapiens p-STAT3
STX-0119 Western Blot Influence on protein activity 2.00 µM SCC3 Homo sapiens p-STAT3
STX-0119 Western Blot Influence on protein activity 5.00 µM SCC3 Homo sapiens p-STAT3
STX-0119 Western Blot Influence on protein activity 10.00 µM SCC3 Homo sapiens p-STAT3
STX-0119 Western Blot Influence on protein activity 20.00 µM SCC3 Homo sapiens p-STAT3
STX-0119 Western Blot Influence on protein activity 2.00 µM SCC3 Homo sapiens STAT3
STX-0119 Western Blot Influence on protein activity 5.00 µM SCC3 Homo sapiens STAT3
STX-0119 Western Blot Influence on protein activity 10.00 µM SCC3 Homo sapiens STAT3
STX-0119 Western Blot Influence on protein activity 20.00 µM SCC3 Homo sapiens STAT3
STX-0119 Western Blot Influence on protein activity 2.00 µM SCC3 Homo sapiens
STX-0119 Western Blot Influence on protein activity 5.00 µM SCC3 Homo sapiens
STX-0119 Western Blot Influence on protein activity 10.00 µM SCC3 Homo sapiens
STX-0119 Western Blot Influence on protein activity 20.00 µM SCC3 Homo sapiens
STX-0119 Western Blot Influence on dowstream target genes expression 2.00 µM SCC3 Homo sapiens p-STAT3
STX-0119 Western Blot Influence on dowstream target genes expression 5.00 µM SCC3 Homo sapiens p-STAT3
STX-0119 Western Blot Influence on dowstream target genes expression 10.00 µM SCC3 Homo sapiens p-STAT3
STX-0119 Western Blot Influence on dowstream target genes expression 20.00 µM SCC3 Homo sapiens p-STAT3
STX-0119 Western Blot Influence on dowstream target genes expression 2.00 µM SCC3 Homo sapiens STAT3
STX-0119 Western Blot Influence on dowstream target genes expression 5.00 µM SCC3 Homo sapiens STAT3
STX-0119 Western Blot Influence on dowstream target genes expression 10.00 µM SCC3 Homo sapiens STAT3
STX-0119 Western Blot Influence on dowstream target genes expression 20.00 µM SCC3 Homo sapiens STAT3
STX-0119 Western Blot Influence on dowstream target genes expression 2.00 µM SCC3 Homo sapiens
STX-0119 Western Blot Influence on dowstream target genes expression 5.00 µM SCC3 Homo sapiens
STX-0119 Western Blot Influence on dowstream target genes expression 10.00 µM SCC3 Homo sapiens
STX-0119 Western Blot Influence on dowstream target genes expression 20.00 µM SCC3 Homo sapiens
STX-0119 Western Blot Influence on dowstream target genes expression 2.00 µM SCC3 Homo sapiens
STX-0119 Western Blot Influence on dowstream target genes expression 5.00 µM SCC3 Homo sapiens
STX-0119 Western Blot Influence on dowstream target genes expression 10.00 µM SCC3 Homo sapiens
STX-0119 Western Blot Influence on dowstream target genes expression 20.00 µM SCC3 Homo sapiens
STX-0119 Western Blot Influence on dowstream target genes expression 2.00 µM SCC3 Homo sapiens
STX-0119 Western Blot Influence on dowstream target genes expression 5.00 µM SCC3 Homo sapiens
STX-0119 Western Blot Influence on dowstream target genes expression 10.00 µM SCC3 Homo sapiens
STX-0119 Western Blot Influence on dowstream target genes expression 20.00 µM SCC3 Homo sapiens
STX-0119 Western Blot Influence on dowstream target genes expression 2.00 µM SCC3 Homo sapiens
STX-0119 Western Blot Influence on dowstream target genes expression 5.00 µM SCC3 Homo sapiens
STX-0119 Western Blot Influence on dowstream target genes expression 10.00 µM SCC3 Homo sapiens
STX-0119 Western Blot Influence on dowstream target genes expression 20.00 µM SCC3 Homo sapiens
STX-0119 Western Blot Influence on dowstream target genes expression 2.00 µM SCC3 Homo sapiens
STX-0119 Western Blot Influence on dowstream target genes expression 5.00 µM SCC3 Homo sapiens
STX-0119 Western Blot Influence on dowstream target genes expression 10.00 µM SCC3 Homo sapiens
STX-0119 Western Blot Influence on dowstream target genes expression 20.00 µM SCC3 Homo sapiens
STX-0119 Western Blot Influence on dowstream target genes expression 2.00 µM SCC3 Homo sapiens
STX-0119 Western Blot Influence on dowstream target genes expression 5.00 µM SCC3 Homo sapiens
STX-0119 Western Blot Influence on dowstream target genes expression 10.00 µM SCC3 Homo sapiens
STX-0119 Western Blot Influence on dowstream target genes expression 20.00 µM SCC3 Homo sapiens
STX-0119 Flow cytometry Influence on cell apoptosis 20.00 µM Jurkat Homo sapiens
STX-0119 Flow cytometry Influence on cell apoptosis 20.00 µM SCC3 Homo sapiens
STX-0119 Flow cytometry Influence on cell apoptosis 36.00 µM U937 Homo sapiens
STX-0119 Western Blot Influence on protein translocation 20.00 µM SCC3 Homo sapiens p-STAT3 (nucleus)
STX-0119 Western Blot Influence on protein translocation 20.00 µM SCC3 Homo sapiens p-STAT3 (cytoplasm)
STX-0119 Western Blot Influence on protein translocation 20.00 µM SCC3 Homo sapiens STAT3 (nucelus)
STX-0119 Western Blot Influence on protein translocation 20.00 µM SCC3 Homo sapiens STAT3 (cytoplam)
STX-0119 Tumor volume Influence on tumor growth 40.00 mg/kg SCC3 (xenograft) Mus musculus BALB/cA-nu/nu
STX-0119 Tumor volume Influence on tumor growth 160.00 mg/kg SCC3 (xenograft) Mus musculus BALB/cA-nu/nu
STX-0119 Body weight Influence on tumor growth 40.00 mg/kg SCC3 (xenograft) Mus musculus BALB/cA-nu/nu
STX-0119 Body weight Influence on tumor growth 160.00 mg/kg SCC3 (xenograft) Mus musculus BALB/cA-nu/nu
STX-0119 Western Blot Influence on protein activity in tumor tissue 80.00 mg/kg SCC3 (xenograft) Mus musculus BALB/cA-nu/nu p-STAT3
STX-0119 Western Blot Influence on protein activity in tumor tissue 160.00 mg/kg SCC3 (xenograft) Mus musculus BALB/cA-nu/nu p-STAT3
STX-0119 Western Blot Influence on protein activity in tumor tissue 80.00 mg/kg SCC3 (xenograft) Mus musculus BALB/cA-nu/nu STAT3
STX-0119 Western Blot Influence on protein activity in tumor tissue 160.00 mg/kg SCC3 (xenograft) Mus musculus BALB/cA-nu/nu STAT3
STX-0119 Western Blot Influence on dowstream target genes expression in tumor tissue 80.00 mg/kg SCC3 (xenograft) Mus musculus BALB/cA-nu/nu
STX-0119 Western Blot Influence on dowstream target genes expression in tumor tissue 160.00 mg/kg SCC3 (xenograft) Mus musculus BALB/cA-nu/nu
STX-0119 Western Blot Influence on dowstream target genes expression in tumor tissue 80.00 mg/kg SCC3 (xenograft) Mus musculus BALB/cA-nu/nu
STX-0119 Western Blot Influence on dowstream target genes expression in tumor tissue 160.00 mg/kg SCC3 (xenograft) Mus musculus BALB/cA-nu/nu
STX-0119 Western Blot Influence on dowstream target genes expression in tumor tissue 80.00 mg/kg SCC3 (xenograft) Mus musculus BALB/cA-nu/nu
STX-0119 Western Blot Influence on dowstream target genes expression in tumor tissue 160.00 mg/kg SCC3 (xenograft) Mus musculus BALB/cA-nu/nu
STX-0119 Western Blot Influence on dowstream target genes expression in tumor tissue 80.00 mg/kg SCC3 (xenograft) Mus musculus BALB/cA-nu/nu
STX-0119 Western Blot Influence on dowstream target genes expression in tumor tissue 160.00 mg/kg SCC3 (xenograft) Mus musculus BALB/cA-nu/nu
STX-0119 Hematoxylin and eosin staining Influence on protein activity in tumor tissue 160.00 mg/kg SCC3 (xenograft) Mus musculus BALB/cA-nu/nu
STX-0119 Immunostaining Influence on protein activity in tumor tissue 160.00 mg/kg SCC3 (xenograft) Mus musculus BALB/cA-nu/nu
STX-0119 Immunostaining Influence on protein activity in tumor tissue 160.00 mg/kg SCC3 (xenograft) Mus musculus BALB/cA-nu/nu
STX-0119 Immunostaining Influence on protein activity in tumor tissue 160.00 mg/kg SCC3 (xenograft) Mus musculus BALB/cA-nu/nu p-STAT3
STX-0119 Immunostaining Influence on protein activity in tumor tissue 160.00 mg/kg SCC3 (xenograft) Mus musculus BALB/cA-nu/nu STAT3
STX-0119 FRET Influence on protein activity 10.00 µM HEK293 Homo sapiens STAT3-CFP
STX-0119 FRET Influence on protein activity 20.00 µM HEK293 Homo sapiens STAT3-CFP
STX-0119 FRET Influence on protein activity 50.00 µM HEK293 Homo sapiens STAT3-CFP
STX-0119 FRET Influence on protein activity 10.00 µM HEK293 Homo sapiens STAT3-YFP
STX-0119 FRET Influence on protein activity 20.00 µM HEK293 Homo sapiens STAT3-YFP
STX-0119 FRET Influence on protein activity 50.00 µM HEK293 Homo sapiens STAT3-YFP
STX-0119 Chromatin immunoprecipitation Influence on protein activity 10.00 µM MDA-MB-468 Homo sapiens STAT3
STX-0119 Chromatin immunoprecipitation Influence on protein activity 20.00 µM MDA-MB-468 Homo sapiens STAT3
STX-0119 Chromatin immunoprecipitation Influence on protein activity 50.00 µM MDA-MB-468 Homo sapiens STAT3
STX-0119 Western Blot Influence on protein activity 10.00 µM MDA-MB-468 Homo sapiens p-STAT3 (Y705)
STX-0119 Western Blot Influence on protein activity 20.00 µM MDA-MB-468 Homo sapiens p-STAT3 (Y705)
STX-0119 Western Blot Influence on protein activity 50.00 µM MDA-MB-468 Homo sapiens p-STAT3 (Y705)
STX-0119 Western Blot Influence on protein activity 10.00 µM MDA-MB-468 Homo sapiens STAT3
STX-0119 Western Blot Influence on protein activity 20.00 µM MDA-MB-468 Homo sapiens STAT3
STX-0119 Western Blot Influence on protein activity 50.00 µM MDA-MB-468 Homo sapiens STAT3
STX-0119 Western Blot Influence on protein activity 10.00 µM MDA-MB-468 Homo sapiens
STX-0119 Western Blot Influence on protein activity 20.00 µM MDA-MB-468 Homo sapiens
STX-0119 Western Blot Influence on protein activity 50.00 µM MDA-MB-468 Homo sapiens
STX-0119 Western Blot Influence on protein activity 10.00 µM MDA-MB-468 Homo sapiens
STX-0119 Western Blot Influence on protein activity 20.00 µM MDA-MB-468 Homo sapiens
STX-0119 Western Blot Influence on protein activity 50.00 µM MDA-MB-468 Homo sapiens
STX-0119 Western Blot Influence on protein activity 10.00 µM MDA-MB-468 Homo sapiens
STX-0119 Western Blot Influence on protein activity 20.00 µM MDA-MB-468 Homo sapiens
STX-0119 Western Blot Influence on protein activity 50.00 µM MDA-MB-468 Homo sapiens
STX-0119 Western Blot Influence on protein activity 10.00 µM MDA-MB-468 Homo sapiens
STX-0119 Western Blot Influence on protein activity 20.00 µM MDA-MB-468 Homo sapiens
STX-0119 Western Blot Influence on protein activity 50.00 µM MDA-MB-468 Homo sapiens
STX-0119 Western Blot Influence on protein activity in precence of IFNα 25.00 µM HMEC Homo sapiens p-STAT1
STX-0119 Western Blot Influence on protein activity in precence of IFNα 12.50 µM HMEC Homo sapiens p-STAT1
STX-0119 Western Blot Influence on protein activity in precence of IFNα 6.25 µM HMEC Homo sapiens p-STAT1
STX-0119 Western Blot Influence on protein activity in precence of IFNα 25.00 µM HMEC Homo sapiens STAT1
STX-0119 Western Blot Influence on protein activity in precence of IFNα 12.50 µM HMEC Homo sapiens STAT1
STX-0119 Western Blot Influence on protein activity in precence of IFNα 6.25 µM HMEC Homo sapiens STAT1
STX-0119 Western Blot Influence on protein activity in precence of IFNα 25.00 µM HMEC Homo sapiens p-STAT2
STX-0119 Western Blot Influence on protein activity in precence of IFNα 12.50 µM HMEC Homo sapiens p-STAT2
STX-0119 Western Blot Influence on protein activity in precence of IFNα 6.25 µM HMEC Homo sapiens p-STAT2
STX-0119 Western Blot Influence on protein activity in precence of IFNα 25.00 µM HMEC Homo sapiens STAT2
STX-0119 Western Blot Influence on protein activity in precence of IFNα 12.50 µM HMEC Homo sapiens STAT2
STX-0119 Western Blot Influence on protein activity in precence of IFNα 6.25 µM HMEC Homo sapiens STAT2
STX-0119 Western Blot Influence on protein activity in precence of IFNα 25.00 µM HMEC Homo sapiens p-STAT3
STX-0119 Western Blot Influence on protein activity in precence of IFNα 12.50 µM HMEC Homo sapiens p-STAT3
STX-0119 Western Blot Influence on protein activity in precence of IFNα 6.25 µM HMEC Homo sapiens p-STAT3
STX-0119 Western Blot Influence on protein activity in precence of IFNα 25.00 µM HMEC Homo sapiens STAT3
STX-0119 Western Blot Influence on protein activity in precence of IFNα 12.50 µM HMEC Homo sapiens STAT3
STX-0119 Western Blot Influence on protein activity in precence of IFNα 6.25 µM HMEC Homo sapiens STAT3
STX-0119 Western Blot Influence on protein activity in precence of IFNα 25.00 µM HMEC Homo sapiens
STX-0119 Western Blot Influence on protein activity in precence of IFNα 12.50 µM HMEC Homo sapiens
STX-0119 Western Blot Influence on protein activity in precence of IFNα 6.25 µM HMEC Homo sapiens
STX-0119 RT-qPCR Influence on gene expression in precence of IFNα 25.00 µM HMEC Homo sapiens
STX-0119 RT-qPCR Influence on gene expression in precence of IFNα 12.50 µM HMEC Homo sapiens
STX-0119 RT-qPCR Influence on gene expression in precence of IFNα 6.25 µM HMEC Homo sapiens
STX-0119 RT-qPCR Influence on gene expression in precence of IFNα 25.00 µM HMEC Homo sapiens
STX-0119 RT-qPCR Influence on gene expression in precence of IFNα 12.50 µM HMEC Homo sapiens
STX-0119 RT-qPCR Influence on gene expression in precence of IFNα 6.25 µM HMEC Homo sapiens
STX-0119 RT-qPCR Influence on gene expression in precence of IFNα 25.00 µM HMEC Homo sapiens
STX-0119 RT-qPCR Influence on gene expression in precence of IFNα 12.50 µM HMEC Homo sapiens
STX-0119 RT-qPCR Influence on gene expression in precence of IFNα 6.25 µM HMEC Homo sapiens
STX-0119 RT-qPCR Influence on gene expression in precence of IFNα 25.00 µM HMEC Homo sapiens
STX-0119 RT-qPCR Influence on gene expression in precence of IFNα 12.50 µM HMEC Homo sapiens
STX-0119 RT-qPCR Influence on gene expression in precence of IFNα 6.25 µM HMEC Homo sapiens
STX-0119 RT-qPCR Influence on gene expression in precence of IFNγLPS 25.00 µM HMEC Homo sapiens
STX-0119 RT-qPCR Influence on gene expression in precence of IFNγLPS 12.50 µM HMEC Homo sapiens
STX-0119 RT-qPCR Influence on gene expression in precence of IFNγLPS 6.25 µM HMEC Homo sapiens
STX-0119 RT-qPCR Influence on gene expression in precence of IFNγLPS 25.00 µM HMEC Homo sapiens
STX-0119 RT-qPCR Influence on gene expression in precence of IFNγLPS 12.50 µM HMEC Homo sapiens
STX-0119 RT-qPCR Influence on gene expression in precence of IFNγLPS 6.25 µM HMEC Homo sapiens
STX-0119 RT-qPCR Influence on gene expression in precence of IFNγLPS 25.00 µM HMEC Homo sapiens
STX-0119 RT-qPCR Influence on gene expression in precence of IFNγLPS 12.50 µM HMEC Homo sapiens
STX-0119 RT-qPCR Influence on gene expression in precence of IFNγLPS 6.25 µM HMEC Homo sapiens
STX-0119 RT-qPCR Influence on gene expression in precence of IFNγLPS 25.00 µM HMEC Homo sapiens
STX-0119 RT-qPCR Influence on gene expression in precence of IFNγLPS 12.50 µM HMEC Homo sapiens
STX-0119 RT-qPCR Influence on gene expression in precence of IFNγLPS 6.25 µM HMEC Homo sapiens
STX-0119 RT-qPCR Influence on gene expression in precence of IFNγLPS 25.00 µM HMEC Homo sapiens
STX-0119 RT-qPCR Influence on gene expression in precence of IFNγLPS 12.50 µM HMEC Homo sapiens
STX-0119 RT-qPCR Influence on gene expression in precence of IFNγLPS 6.25 µM HMEC Homo sapiens
STX-0119 RT-qPCR Influence on gene expression in precence of IFNγLPS 25.00 µM HMEC Homo sapiens
STX-0119 RT-qPCR Influence on gene expression in precence of IFNγLPS 12.50 µM HMEC Homo sapiens
STX-0119 RT-qPCR Influence on gene expression in precence of IFNγLPS 6.25 µM HMEC Homo sapiens
STX-0119 RT-qPCR Influence on gene expression in precence of IFNγLPS 25.00 µM HMEC Homo sapiens
STX-0119 RT-qPCR Influence on gene expression in precence of IFNγLPS 12.50 µM HMEC Homo sapiens
STX-0119 RT-qPCR Influence on gene expression in precence of IFNγLPS 6.25 µM HMEC Homo sapiens
STX-0119 Wound healing assay Influence on cell motility in precence of IFNγLPS 25.00 µM HMEC Homo sapiens
STX-0119 Adhesion assay Influence on cell motility in precence of IFNγLPS 25.00 µM HUVECS Homo sapiens
STX-0119 Constriction assay Influence on artery contractility in precence of IFNγLPS and noradrenaline 10.00 nM mesenteric artery Mus musculus