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Experiments

Compound Investigated event Experiment type Concentration Cell line Organism Animal model Stat protein Details
STX-0119 Influence on protein activity Western Blot 10.00 µM SCC3 Homo sapiens p-STAT3
STX-0119 Influence on protein activity Western Blot 10.00 µM SCC3 Homo sapiens STAT3
STX-0119 Influence on protein activity Western Blot 10.00 µM SCC3 Homo sapiens
STX-0119 Influence on dowstream target genes expression Western Blot 10.00 µM SCC3 Homo sapiens p-STAT3
STX-0119 Influence on dowstream target genes expression Western Blot 10.00 µM SCC3 Homo sapiens STAT3
STX-0119 Influence on dowstream target genes expression Western Blot 10.00 µM SCC3 Homo sapiens
STX-0119 Influence on dowstream target genes expression Western Blot 10.00 µM SCC3 Homo sapiens
STX-0119 Influence on dowstream target genes expression Western Blot 10.00 µM SCC3 Homo sapiens
STX-0119 Influence on dowstream target genes expression Western Blot 10.00 µM SCC3 Homo sapiens
STX-0119 Influence on dowstream target genes expression Western Blot 10.00 µM SCC3 Homo sapiens
STX-0119 Influence on dowstream target genes expression Western Blot 10.00 µM SCC3 Homo sapiens
STX-0119 Influence on protein activity FRET 10.00 µM HEK293 Homo sapiens STAT3-CFP
STX-0119 Influence on protein activity FRET 10.00 µM HEK293 Homo sapiens STAT3-YFP
STX-0119 Influence on protein activity Chromatin immunoprecipitation 10.00 µM MDA-MB-468 Homo sapiens STAT3
STX-0119 Influence on protein activity Western Blot 10.00 µM MDA-MB-468 Homo sapiens p-STAT3 (Y705)
STX-0119 Influence on protein activity Western Blot 10.00 µM MDA-MB-468 Homo sapiens STAT3
STX-0119 Influence on protein activity Western Blot 10.00 µM MDA-MB-468 Homo sapiens
STX-0119 Influence on protein activity Western Blot 10.00 µM MDA-MB-468 Homo sapiens
STX-0119 Influence on protein activity Western Blot 10.00 µM MDA-MB-468 Homo sapiens
STX-0119 Influence on protein activity Western Blot 10.00 µM MDA-MB-468 Homo sapiens
STX-0119 Influence on artery contractility in precence of IFNγLPS and noradrenaline Constriction assay 10.00 nM mesenteric artery Mus musculus