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Experiments

Compound Investigated event Experiment type Concentration Cell line Organism Animal model Stat protein Details
STX-0119 Influence on cell proliferation WST-1 N/A µM SCC3 Homo sapiens
STX-0119 Influence on protein activity Phosphorylation assay 5.00 µM SCC3 Homo sapiens p-STAT3
STX-0119 Influence on protein activity Phosphorylation assay 20.00 µM SCC3 Homo sapiens p-STAT3
STX-0119 Influence on protein activity Western Blot 2.00 µM SCC3 Homo sapiens p-STAT3
STX-0119 Influence on protein activity Western Blot 5.00 µM SCC3 Homo sapiens p-STAT3
STX-0119 Influence on protein activity Western Blot 10.00 µM SCC3 Homo sapiens p-STAT3
STX-0119 Influence on protein activity Western Blot 20.00 µM SCC3 Homo sapiens p-STAT3
STX-0119 Influence on protein activity Western Blot 2.00 µM SCC3 Homo sapiens STAT3
STX-0119 Influence on protein activity Western Blot 5.00 µM SCC3 Homo sapiens STAT3
STX-0119 Influence on protein activity Western Blot 10.00 µM SCC3 Homo sapiens STAT3
STX-0119 Influence on protein activity Western Blot 20.00 µM SCC3 Homo sapiens STAT3
STX-0119 Influence on protein activity Western Blot 2.00 µM SCC3 Homo sapiens
STX-0119 Influence on protein activity Western Blot 5.00 µM SCC3 Homo sapiens
STX-0119 Influence on protein activity Western Blot 10.00 µM SCC3 Homo sapiens
STX-0119 Influence on protein activity Western Blot 20.00 µM SCC3 Homo sapiens
STX-0119 Influence on dowstream target genes expression Western Blot 2.00 µM SCC3 Homo sapiens p-STAT3
STX-0119 Influence on dowstream target genes expression Western Blot 5.00 µM SCC3 Homo sapiens p-STAT3
STX-0119 Influence on dowstream target genes expression Western Blot 10.00 µM SCC3 Homo sapiens p-STAT3
STX-0119 Influence on dowstream target genes expression Western Blot 20.00 µM SCC3 Homo sapiens p-STAT3
STX-0119 Influence on dowstream target genes expression Western Blot 2.00 µM SCC3 Homo sapiens STAT3
STX-0119 Influence on dowstream target genes expression Western Blot 5.00 µM SCC3 Homo sapiens STAT3
STX-0119 Influence on dowstream target genes expression Western Blot 10.00 µM SCC3 Homo sapiens STAT3
STX-0119 Influence on dowstream target genes expression Western Blot 20.00 µM SCC3 Homo sapiens STAT3
STX-0119 Influence on dowstream target genes expression Western Blot 2.00 µM SCC3 Homo sapiens
STX-0119 Influence on dowstream target genes expression Western Blot 5.00 µM SCC3 Homo sapiens
STX-0119 Influence on dowstream target genes expression Western Blot 10.00 µM SCC3 Homo sapiens
STX-0119 Influence on dowstream target genes expression Western Blot 20.00 µM SCC3 Homo sapiens
STX-0119 Influence on dowstream target genes expression Western Blot 2.00 µM SCC3 Homo sapiens
STX-0119 Influence on dowstream target genes expression Western Blot 5.00 µM SCC3 Homo sapiens
STX-0119 Influence on dowstream target genes expression Western Blot 10.00 µM SCC3 Homo sapiens
STX-0119 Influence on dowstream target genes expression Western Blot 20.00 µM SCC3 Homo sapiens
STX-0119 Influence on dowstream target genes expression Western Blot 2.00 µM SCC3 Homo sapiens
STX-0119 Influence on dowstream target genes expression Western Blot 5.00 µM SCC3 Homo sapiens
STX-0119 Influence on dowstream target genes expression Western Blot 10.00 µM SCC3 Homo sapiens
STX-0119 Influence on dowstream target genes expression Western Blot 20.00 µM SCC3 Homo sapiens
STX-0119 Influence on dowstream target genes expression Western Blot 2.00 µM SCC3 Homo sapiens
STX-0119 Influence on dowstream target genes expression Western Blot 5.00 µM SCC3 Homo sapiens
STX-0119 Influence on dowstream target genes expression Western Blot 10.00 µM SCC3 Homo sapiens
STX-0119 Influence on dowstream target genes expression Western Blot 20.00 µM SCC3 Homo sapiens
STX-0119 Influence on dowstream target genes expression Western Blot 2.00 µM SCC3 Homo sapiens
STX-0119 Influence on dowstream target genes expression Western Blot 5.00 µM SCC3 Homo sapiens
STX-0119 Influence on dowstream target genes expression Western Blot 10.00 µM SCC3 Homo sapiens
STX-0119 Influence on dowstream target genes expression Western Blot 20.00 µM SCC3 Homo sapiens
STX-0119 Influence on dowstream target genes expression Western Blot 2.00 µM SCC3 Homo sapiens
STX-0119 Influence on dowstream target genes expression Western Blot 5.00 µM SCC3 Homo sapiens
STX-0119 Influence on dowstream target genes expression Western Blot 10.00 µM SCC3 Homo sapiens
STX-0119 Influence on dowstream target genes expression Western Blot 20.00 µM SCC3 Homo sapiens
STX-0119 Influence on cell apoptosis Flow cytometry 20.00 µM SCC3 Homo sapiens
STX-0119 Influence on protein translocation Western Blot 20.00 µM SCC3 Homo sapiens p-STAT3 (nucleus)
STX-0119 Influence on protein translocation Western Blot 20.00 µM SCC3 Homo sapiens p-STAT3 (cytoplasm)