Toosendanin |
Luciferase reporter assay |
Influence on protein activity |
25.00 nM |
143B |
Homo sapiens |
|
|
|
Toosendanin |
Luciferase reporter assay |
Influence on protein activity |
50.00 nM |
143B |
Homo sapiens |
|
|
|
Toosendanin |
Luciferase reporter assay |
Influence on protein activity |
100.00 nM |
143B |
Homo sapiens |
|
|
|
Toosendanin |
Luciferase reporter assay |
Influence on protein activity |
200.00 nM |
HOS |
Homo sapiens |
|
|
|
Toosendanin |
Luciferase reporter assay |
Influence on protein activity |
25.00 nM |
HOS |
Homo sapiens |
|
|
|
Toosendanin |
Luciferase reporter assay |
Influence on protein activity |
50.00 nM |
HOS |
Homo sapiens |
|
|
|
Toosendanin |
Luciferase reporter assay |
Influence on protein activity |
100.00 nM |
HOS |
Homo sapiens |
|
|
|
Toosendanin |
Western Blot |
Influence on protein activity |
50.00 nM |
143B |
Homo sapiens |
|
p-STAT3(Y705) |
|
Toosendanin |
Western Blot |
Influence on protein activity |
100.00 nM |
143B |
Homo sapiens |
|
p-STAT3(Y705) |
|
Toosendanin |
Western Blot |
Influence on protein activity |
200.00 nM |
143B |
Homo sapiens |
|
p-STAT3(Y705) |
|
Toosendanin |
Western Blot |
Influence on protein activity |
50.00 nM |
HOS |
Homo sapiens |
|
p-STAT3(Y705) |
|
Toosendanin |
Western Blot |
Influence on protein activity |
100.00 nM |
HOS |
Homo sapiens |
|
p-STAT3(Y705) |
|
Toosendanin |
Western Blot |
Influence on protein activity |
200.00 nM |
HOS |
Homo sapiens |
|
p-STAT3(Y705) |
|
Toosendanin |
Western Blot |
Influence on protein activity |
50.00 nM |
MG63.2 |
Homo sapiens |
|
p-STAT3(Y705) |
|
Toosendanin |
Western Blot |
Influence on protein activity |
100.00 nM |
MG63.2 |
Homo sapiens |
|
p-STAT3(Y705) |
|
Toosendanin |
Western Blot |
Influence on protein activity |
200.00 nM |
MG63.2 |
Homo sapiens |
|
p-STAT3(Y705) |
|
Toosendanin |
Western Blot |
Influence on protein activity |
50.00 nM |
143B |
Homo sapiens |
|
p-STAT3(S727) |
|
Toosendanin |
Western Blot |
Influence on protein activity |
100.00 nM |
143B |
Homo sapiens |
|
p-STAT3(S727) |
|
Toosendanin |
Western Blot |
Influence on protein activity |
200.00 nM |
143B |
Homo sapiens |
|
p-STAT3(S727) |
|
Toosendanin |
Western Blot |
Influence on protein activity |
50.00 nM |
HOS |
Homo sapiens |
|
p-STAT3(S727) |
|
Toosendanin |
Western Blot |
Influence on protein activity |
100.00 nM |
HOS |
Homo sapiens |
|
p-STAT3(S727) |
|
Toosendanin |
Western Blot |
Influence on protein activity |
200.00 nM |
HOS |
Homo sapiens |
|
p-STAT3(S727) |
|
Toosendanin |
Western Blot |
Influence on protein activity |
50.00 nM |
MG63.2 |
Homo sapiens |
|
p-STAT3(S727) |
|
Toosendanin |
Western Blot |
Influence on protein activity |
100.00 nM |
MG63.2 |
Homo sapiens |
|
p-STAT3(S727) |
|
Toosendanin |
Western Blot |
Influence on protein activity |
200.00 nM |
MG63.2 |
Homo sapiens |
|
p-STAT3(S727) |
|
Toosendanin |
Western Blot |
Influence on protein activity |
50.00 nM |
143B |
Homo sapiens |
|
STAT3 |
|
Toosendanin |
Western Blot |
Influence on protein activity |
100.00 nM |
143B |
Homo sapiens |
|
STAT3 |
|
Toosendanin |
Western Blot |
Influence on protein activity |
200.00 nM |
143B |
Homo sapiens |
|
STAT3 |
|
Toosendanin |
Western Blot |
Influence on protein activity |
50.00 nM |
HOS |
Homo sapiens |
|
STAT3 |
|
Toosendanin |
Western Blot |
Influence on protein activity |
100.00 nM |
HOS |
Homo sapiens |
|
STAT3 |
|
Toosendanin |
Western Blot |
Influence on protein activity |
200.00 nM |
HOS |
Homo sapiens |
|
STAT3 |
|
Toosendanin |
Western Blot |
Influence on protein activity |
50.00 nM |
MG63.2 |
Homo sapiens |
|
STAT3 |
|
Toosendanin |
Western Blot |
Influence on protein activity |
100.00 nM |
MG63.2 |
Homo sapiens |
|
STAT3 |
|
Toosendanin |
Western Blot |
Influence on protein activity |
200.00 nM |
MG63.2 |
Homo sapiens |
|
STAT3 |
|
Toosendanin |
Western Blot |
Influence on protein activity |
50.00 nM |
143B |
Homo sapiens |
|
|
|
Toosendanin |
Western Blot |
Influence on protein activity |
100.00 nM |
143B |
Homo sapiens |
|
|
|
Toosendanin |
Western Blot |
Influence on protein activity |
200.00 nM |
143B |
Homo sapiens |
|
|
|
Toosendanin |
Western Blot |
Influence on protein activity |
50.00 nM |
HOS |
Homo sapiens |
|
|
|
Toosendanin |
Western Blot |
Influence on protein activity |
100.00 nM |
HOS |
Homo sapiens |
|
|
|
Toosendanin |
Western Blot |
Influence on protein activity |
200.00 nM |
HOS |
Homo sapiens |
|
|
|
Toosendanin |
Western Blot |
Influence on protein activity |
50.00 nM |
MG63.2 |
Homo sapiens |
|
|
|
Toosendanin |
Western Blot |
Influence on protein activity |
100.00 nM |
MG63.2 |
Homo sapiens |
|
|
|
Toosendanin |
Western Blot |
Influence on protein activity |
200.00 nM |
MG63.2 |
Homo sapiens |
|
|
|
Toosendanin |
Immunofluorescence |
Influence on protein activity in presence of IL-6 |
100.00 nM |
143B |
Homo sapiens |
|
STAT3 |
|
Toosendanin |
Western Blot |
Influence on protein translocation in presence of IL-6 |
50.00 nM |
143B |
Homo sapiens |
|
STAT3(nucleus) |
|
Toosendanin |
Western Blot |
Influence on protein translocation in presence of IL-6 |
100.00 nM |
143B |
Homo sapiens |
|
STAT3(nucleus) |
|
Toosendanin |
Western Blot |
Influence on protein translocation in presence of IL-6 |
50.00 nM |
143B |
Homo sapiens |
|
|
|
Toosendanin |
Western Blot |
Influence on protein translocation in presence of IL-6 |
100.00 nM |
143B |
Homo sapiens |
|
|
|
Toosendanin |
Western Blot |
Influence on protein translocation in presence of IL-6 |
50.00 nM |
143B |
Homo sapiens |
|
|
|
Toosendanin |
Western Blot |
Influence on protein translocation in presence of IL-6 |
100.00 nM |
143B |
Homo sapiens |
|
|
|
Toosendanin |
Western Blot |
Influence on protein translocation in presence of IL-6 |
50.00 nM |
143B |
Homo sapiens |
|
STAT3(cytoplasm) |
|
Toosendanin |
Western Blot |
Influence on protein translocation in presence of IL-6 |
100.00 nM |
143B |
Homo sapiens |
|
STAT3(cytoplasm) |
|
Toosendanin |
Western Blot |
Influence on protein translocation in presence of IL-6 |
50.00 nM |
143B |
Homo sapiens |
|
|
|
Toosendanin |
Western Blot |
Influence on protein translocation in presence of IL-6 |
100.00 nM |
143B |
Homo sapiens |
|
|
|
Toosendanin |
Western Blot |
Influence on protein translocation in presence of IL-6 |
50.00 nM |
143B |
Homo sapiens |
|
|
|
Toosendanin |
Western Blot |
Influence on protein translocation in presence of IL-6 |
100.00 nM |
143B |
Homo sapiens |
|
|
|
Toosendanin |
EMSA |
Influence on protein-DNA interaction |
50.00 nM |
143B |
Homo sapiens |
|
STAT3 |
|
Toosendanin |
EMSA |
Influence on protein-DNA interaction |
100.00 nM |
143B |
Homo sapiens |
|
STAT3 |
|
Toosendanin |
EMSA |
Influence on protein-DNA interaction |
200.00 nM |
143B |
Homo sapiens |
|
STAT3 |
|
Toosendanin |
RT-PCR |
Influence on expression of STAT3 target genes |
50.00 nM |
143B |
Homo sapiens |
|
|
|
Toosendanin |
RT-PCR |
Influence on expression of STAT3 target genes |
100.00 nM |
143B |
Homo sapiens |
|
|
|
Toosendanin |
RT-PCR |
Influence on expression of STAT3 target genes |
200.00 nM |
143B |
Homo sapiens |
|
|
|
Toosendanin |
RT-PCR |
Influence on expression of STAT3 target genes |
50.00 nM |
143B |
Homo sapiens |
|
|
|
Toosendanin |
RT-PCR |
Influence on expression of STAT3 target genes |
100.00 nM |
143B |
Homo sapiens |
|
|
|
Toosendanin |
RT-PCR |
Influence on expression of STAT3 target genes |
200.00 nM |
143B |
Homo sapiens |
|
|
|
Toosendanin |
RT-PCR |
Influence on expression of STAT3 target genes |
50.00 nM |
143B |
Homo sapiens |
|
|
|
Toosendanin |
RT-PCR |
Influence on expression of STAT3 target genes |
100.00 nM |
143B |
Homo sapiens |
|
|
|
Toosendanin |
RT-PCR |
Influence on expression of STAT3 target genes |
200.00 nM |
143B |
Homo sapiens |
|
|
|
Toosendanin |
RT-PCR |
Influence on expression of STAT3 target genes |
50.00 nM |
143B |
Homo sapiens |
|
|
|
Toosendanin |
RT-PCR |
Influence on expression of STAT3 target genes |
100.00 nM |
143B |
Homo sapiens |
|
|
|
Toosendanin |
RT-PCR |
Influence on expression of STAT3 target genes |
200.00 nM |
143B |
Homo sapiens |
|
|
|
Toosendanin |
RT-PCR |
Influence on expression of STAT3 target genes |
50.00 nM |
143B |
Homo sapiens |
|
|
|
Toosendanin |
RT-PCR |
Influence on expression of STAT3 target genes |
100.00 nM |
143B |
Homo sapiens |
|
|
|
Toosendanin |
RT-PCR |
Influence on expression of STAT3 target genes |
200.00 nM |
143B |
Homo sapiens |
|
|
|
Toosendanin |
RT-PCR |
Influence on expression of STAT3 target genes |
50.00 nM |
143B |
Homo sapiens |
|
|
|
Toosendanin |
RT-PCR |
Influence on expression of STAT3 target genes |
100.00 nM |
143B |
Homo sapiens |
|
|
|
Toosendanin |
RT-PCR |
Influence on expression of STAT3 target genes |
200.00 nM |
143B |
Homo sapiens |
|
|
|
Toosendanin |
RT-PCR |
Influence on expression of STAT3 target genes |
50.00 nM |
143B |
Homo sapiens |
|
|
|
Toosendanin |
RT-PCR |
Influence on expression of STAT3 target genes |
100.00 nM |
143B |
Homo sapiens |
|
|
|
Toosendanin |
RT-PCR |
Influence on expression of STAT3 target genes |
200.00 nM |
143B |
Homo sapiens |
|
|
|
Toosendanin |
Western Blot |
Influence on protein activity |
50.00 nM |
143B |
Homo sapiens |
|
|
|
Toosendanin |
Western Blot |
Influence on protein activity |
100.00 nM |
143B |
Homo sapiens |
|
|
|
Toosendanin |
Western Blot |
Influence on protein activity |
200.00 nM |
143B |
Homo sapiens |
|
|
|
Toosendanin |
Western Blot |
Influence on protein activity |
50.00 nM |
143B |
Homo sapiens |
|
|
|
Toosendanin |
Western Blot |
Influence on protein activity |
100.00 nM |
143B |
Homo sapiens |
|
|
|
Toosendanin |
Western Blot |
Influence on protein activity |
200.00 nM |
143B |
Homo sapiens |
|
|
|
Toosendanin |
Western Blot |
Influence on protein activity |
50.00 nM |
143B |
Homo sapiens |
|
|
|
Toosendanin |
Western Blot |
Influence on protein activity |
100.00 nM |
143B |
Homo sapiens |
|
|
|
Toosendanin |
Western Blot |
Influence on protein activity |
200.00 nM |
143B |
Homo sapiens |
|
|
|
Toosendanin |
Western Blot |
Influence on protein activity |
50.00 nM |
143B |
Homo sapiens |
|
|
|
Toosendanin |
Western Blot |
Influence on protein activity |
100.00 nM |
143B |
Homo sapiens |
|
|
|
Toosendanin |
Western Blot |
Influence on protein activity |
200.00 nM |
143B |
Homo sapiens |
|
|
|
Toosendanin |
Western Blot |
Influence on protein activity |
50.00 nM |
143B |
Homo sapiens |
|
|
|
Toosendanin |
Western Blot |
Influence on protein activity |
100.00 nM |
143B |
Homo sapiens |
|
|
|
Toosendanin |
Western Blot |
Influence on protein activity |
200.00 nM |
143B |
Homo sapiens |
|
|
|
Toosendanin |
Western Blot |
Influence on protein activity |
50.00 nM |
143B |
Homo sapiens |
|
|
|
Toosendanin |
Western Blot |
Influence on protein activity |
100.00 nM |
143B |
Homo sapiens |
|
|
|
Toosendanin |
Western Blot |
Influence on protein activity |
200.00 nM |
143B |
Homo sapiens |
|
|
|
Toosendanin |
Western Blot |
Influence on protein activity |
50.00 nM |
MG63.2 |
Homo sapiens |
|
|
|
Toosendanin |
Western Blot |
Influence on protein activity |
100.00 nM |
MG63.2 |
Homo sapiens |
|
|
|
Toosendanin |
Western Blot |
Influence on protein activity |
200.00 nM |
MG63.2 |
Homo sapiens |
|
|
|
Toosendanin |
Western Blot |
Influence on protein activity |
50.00 nM |
MG63.2 |
Homo sapiens |
|
|
|
Toosendanin |
Western Blot |
Influence on protein activity |
100.00 nM |
MG63.2 |
Homo sapiens |
|
|
|
Toosendanin |
Western Blot |
Influence on protein activity |
200.00 nM |
MG63.2 |
Homo sapiens |
|
|
|
Toosendanin |
Western Blot |
Influence on protein activity |
50.00 nM |
MG63.2 |
Homo sapiens |
|
|
|
Toosendanin |
Western Blot |
Influence on protein activity |
100.00 nM |
MG63.2 |
Homo sapiens |
|
|
|
Toosendanin |
Western Blot |
Influence on protein activity |
200.00 nM |
MG63.2 |
Homo sapiens |
|
|
|
Toosendanin |
Western Blot |
Influence on protein activity |
50.00 nM |
MG63.2 |
Homo sapiens |
|
|
|
Toosendanin |
Western Blot |
Influence on protein activity |
100.00 nM |
MG63.2 |
Homo sapiens |
|
|
|
Toosendanin |
Western Blot |
Influence on protein activity |
200.00 nM |
MG63.2 |
Homo sapiens |
|
|
|
Toosendanin |
Western Blot |
Influence on protein activity |
50.00 nM |
MG63.2 |
Homo sapiens |
|
|
|
Toosendanin |
Western Blot |
Influence on protein activity |
100.00 nM |
MG63.2 |
Homo sapiens |
|
|
|
Toosendanin |
Western Blot |
Influence on protein activity |
200.00 nM |
MG63.2 |
Homo sapiens |
|
|
|
Toosendanin |
Western Blot |
Influence on protein activity |
50.00 nM |
MG63.2 |
Homo sapiens |
|
|
|
Toosendanin |
Western Blot |
Influence on protein activity |
100.00 nM |
MG63.2 |
Homo sapiens |
|
|
|
Toosendanin |
Western Blot |
Influence on protein activity |
200.00 nM |
MG63.2 |
Homo sapiens |
|
|
|
Toosendanin |
Chromatin immunoprecipitation assay |
Influence on protein-DNA interaction |
50.00 nM |
143B |
Homo sapiens |
|
STAT3:Bcl2 |
|
Toosendanin |
Chromatin immunoprecipitation assay |
Influence on protein-DNA interaction |
100.00 nM |
143B |
Homo sapiens |
|
STAT3:Bcl2 |
|
Toosendanin |
Chromatin immunoprecipitation assay |
Influence on protein-DNA interaction |
200.00 nM |
143B |
Homo sapiens |
|
STAT3:Bcl2 |
|
Toosendanin |
Chromatin immunoprecipitation assay |
Influence on protein-DNA interaction |
50.00 nM |
143B |
Homo sapiens |
|
STAT3:VEGF |
|
Toosendanin |
Chromatin immunoprecipitation assay |
Influence on protein-DNA interaction |
100.00 nM |
143B |
Homo sapiens |
|
STAT3:VEGF |
|
Toosendanin |
Chromatin immunoprecipitation assay |
Influence on protein-DNA interaction |
200.00 nM |
143B |
Homo sapiens |
|
STAT3:VEGF |
|
Toosendanin |
Chromatin immunoprecipitation assay |
Influence on protein-DNA interaction |
50.00 nM |
143B |
Homo sapiens |
|
STAT3:SOCS3 |
|
Toosendanin |
Chromatin immunoprecipitation assay |
Influence on protein-DNA interaction |
100.00 nM |
143B |
Homo sapiens |
|
STAT3:SOCS3 |
|
Toosendanin |
Chromatin immunoprecipitation assay |
Influence on protein-DNA interaction |
200.00 nM |
143B |
Homo sapiens |
|
STAT3:SOCS3 |
|
Toosendanin |
MTS Assay |
Influence on cell viability |
25.00 nM |
143B |
Homo sapiens |
|
|
|
Toosendanin |
MTS Assay |
Influence on cell viability |
50.00 nM |
143B |
Homo sapiens |
|
|
|
Toosendanin |
MTS Assay |
Influence on cell viability |
100.00 nM |
143B |
Homo sapiens |
|
|
|
Toosendanin |
MTS Assay |
Influence on cell viability |
200.00 nM |
143B |
Homo sapiens |
|
|
|
Toosendanin |
MTS Assay |
Influence on cell viability |
25.00 nM |
HOS |
Homo sapiens |
|
|
|
Toosendanin |
MTS Assay |
Influence on cell viability |
50.00 nM |
HOS |
Homo sapiens |
|
|
|
Toosendanin |
MTS Assay |
Influence on cell viability |
100.00 nM |
HOS |
Homo sapiens |
|
|
|
Toosendanin |
MTS Assay |
Influence on cell viability |
200.00 nM |
HOS |
Homo sapiens |
|
|
|
Toosendanin |
MTS Assay |
Influence on cell viability |
25.00 nM |
MG63.2 |
Homo sapiens |
|
|
|
Toosendanin |
MTS Assay |
Influence on cell viability |
50.00 nM |
MG63.2 |
Homo sapiens |
|
|
|
Toosendanin |
MTS Assay |
Influence on cell viability |
100.00 nM |
MG63.2 |
Homo sapiens |
|
|
|
Toosendanin |
MTS Assay |
Influence on cell viability |
200.00 nM |
MG63.2 |
Homo sapiens |
|
|
|
Toosendanin |
MTS Assay |
Influence on cell viability |
25.00 nM |
MG63 |
Homo sapiens |
|
|
|
Toosendanin |
MTS Assay |
Influence on cell viability |
50.00 nM |
MG63 |
Homo sapiens |
|
|
|
Toosendanin |
MTS Assay |
Influence on cell viability |
100.00 nM |
MG63 |
Homo sapiens |
|
|
|
Toosendanin |
MTS Assay |
Influence on cell viability |
200.00 nM |
MG63 |
Homo sapiens |
|
|
|
Toosendanin |
MTS Assay |
Influence on cell viability |
25.00 nM |
DUNN |
Homo sapiens |
|
|
|
Toosendanin |
MTS Assay |
Influence on cell viability |
50.00 nM |
DUNN |
Homo sapiens |
|
|
|
Toosendanin |
MTS Assay |
Influence on cell viability |
100.00 nM |
DUNN |
Homo sapiens |
|
|
|
Toosendanin |
MTS Assay |
Influence on cell viability |
200.00 nM |
DUNN |
Homo sapiens |
|
|
|
Toosendanin |
MTS Assay |
Influence on cell viability |
25.00 nM |
LM8 |
Homo sapiens |
|
|
|
Toosendanin |
MTS Assay |
Influence on cell viability |
50.00 nM |
LM8 |
Homo sapiens |
|
|
|
Toosendanin |
MTS Assay |
Influence on cell viability |
100.00 nM |
LM8 |
Homo sapiens |
|
|
|
Toosendanin |
MTS Assay |
Influence on cell viability |
200.00 nM |
LM8 |
Homo sapiens |
|
|
|
Toosendanin |
MTS Assay |
Influence on cell viability |
25.00 nM |
hFOB1.19 |
Homo sapiens |
|
|
|
Toosendanin |
MTS Assay |
Influence on cell viability |
50.00 nM |
hFOB1.19 |
Homo sapiens |
|
|
|
Toosendanin |
MTS Assay |
Influence on cell viability |
100.00 nM |
hFOB1.19 |
Homo sapiens |
|
|
|
Toosendanin |
MTS Assay |
Influence on cell viability |
200.00 nM |
hFOB1.19 |
Homo sapiens |
|
|
|
Toosendanin |
MTS Assay |
Influence on cell viability in STAT3 transfected cells |
100.00 nM |
143B |
Homo sapiens |
|
|
|
Toosendanin |
RT-PCR |
Influence on expression of STAT3 target genes in STAT3 transfected cells |
100.00 nM |
143B |
Homo sapiens |
|
|
|
Toosendanin |
RT-PCR |
Influence on expression of STAT3 target genes in STAT3 transfected cells |
100.00 nM |
143B |
Homo sapiens |
|
|
|
Toosendanin |
RT-PCR |
Influence on expression of STAT3 target genes in STAT3 transfected cells |
100.00 nM |
143B |
Homo sapiens |
|
|
|
Toosendanin |
Colony formation assay |
Influence on cell motility |
25.00 nM |
143B |
Homo sapiens |
|
|
|
Toosendanin |
Colony formation assay |
Influence on cell motility |
25.00 nM |
HOS |
Homo sapiens |
|
|
|
Toosendanin |
Colony formation assay |
Influence on cell motility |
25.00 nM |
MG63.2 |
Homo sapiens |
|
|
|
Toosendanin |
Colony formation assay |
Influence on cell motility |
25.00 nM |
MG63 |
Homo sapiens |
|
|
|
Toosendanin |
Flow cytometry- annexin V binding and propidium iodide staining |
Influence on cell apoptosis |
50.00 nM |
143B |
Homo sapiens |
|
|
|
Toosendanin |
Flow cytometry- annexin V binding and propidium iodide staining |
Influence on cell apoptosis |
100.00 nM |
143B |
Homo sapiens |
|
|
|
Toosendanin |
Flow cytometry- annexin V binding and propidium iodide staining |
Influence on cell apoptosis |
200.00 nM |
143B |
Homo sapiens |
|
|
|
Toosendanin |
Flow cytometry- annexin V binding and propidium iodide staining |
Influence on cell apoptosis |
50.00 nM |
MG63.2 |
Homo sapiens |
|
|
|
Toosendanin |
Flow cytometry- annexin V binding and propidium iodide staining |
Influence on cell apoptosis |
100.00 nM |
MG63.2 |
Homo sapiens |
|
|
|
Toosendanin |
Flow cytometry- annexin V binding and propidium iodide staining |
Influence on cell apoptosis |
200.00 nM |
MG63.2 |
Homo sapiens |
|
|
|
Toosendanin |
Tube formation assay |
Influence on cell motility |
50.00 nM |
HUVEC |
Homo sapiens |
|
|
|
Toosendanin |
Tube formation assay |
Influence on cell motility |
100.00 nM |
HUVEC |
Homo sapiens |
|
|
|
Toosendanin |
Tube formation assay |
Influence on cell motility |
200.00 nM |
HUVEC |
Homo sapiens |
|
|
|
Toosendanin |
Invasion assay |
Influence on cell motility |
25.00 nM |
143B |
Homo sapiens |
|
|
|
Toosendanin |
Invasion assay |
Influence on cell motility |
50.00 nM |
143B |
Homo sapiens |
|
|
|
Toosendanin |
Invasion assay |
Influence on cell motility |
100.00 nM |
143B |
Homo sapiens |
|
|
|
Toosendanin |
Invasion assay |
Influence on cell motility |
200.00 nM |
143B |
Homo sapiens |
|
|
|
Toosendanin |
Invasion assay |
Influence on cell motility |
25.00 nM |
MG63.2 |
Homo sapiens |
|
|
|
Toosendanin |
Invasion assay |
Influence on cell motility |
50.00 nM |
MG63.2 |
Homo sapiens |
|
|
|
Toosendanin |
Invasion assay |
Influence on cell motility |
100.00 nM |
MG63.2 |
Homo sapiens |
|
|
|
Toosendanin |
Invasion assay |
Influence on cell motility |
200.00 nM |
MG63.2 |
Homo sapiens |
|
|
|
Toosendanin |
3D culture assay |
Influence on cell motility |
50.00 nM |
143B |
Homo sapiens |
|
|
|
Toosendanin |
3D culture assay |
Influence on cell motility |
100.00 nM |
143B |
Homo sapiens |
|
|
|
Toosendanin |
3D culture assay |
Influence on cell motility |
200.00 nM |
143B |
Homo sapiens |
|
|
|
Toosendanin |
Western Blot |
Influence on EMT |
50.00 nM |
143B |
Homo sapiens |
|
|
|
Toosendanin |
Western Blot |
Influence on EMT |
100.00 nM |
143B |
Homo sapiens |
|
|
|
Toosendanin |
Western Blot |
Influence on EMT |
200.00 nM |
143B |
Homo sapiens |
|
|
|
Toosendanin |
Western Blot |
Influence on EMT |
50.00 nM |
143B |
Homo sapiens |
|
|
|
Toosendanin |
Western Blot |
Influence on EMT |
100.00 nM |
143B |
Homo sapiens |
|
|
|
Toosendanin |
Western Blot |
Influence on EMT |
200.00 nM |
143B |
Homo sapiens |
|
|
|
Toosendanin |
Western Blot |
Influence on EMT |
50.00 nM |
143B |
Homo sapiens |
|
|
|
Toosendanin |
Western Blot |
Influence on EMT |
100.00 nM |
143B |
Homo sapiens |
|
|
|
Toosendanin |
Western Blot |
Influence on EMT |
200.00 nM |
143B |
Homo sapiens |
|
|
|
Toosendanin |
Western Blot |
Influence on EMT |
50.00 nM |
143B |
Homo sapiens |
|
|
|
Toosendanin |
Western Blot |
Influence on EMT |
100.00 nM |
143B |
Homo sapiens |
|
|
|
Toosendanin |
Western Blot |
Influence on EMT |
200.00 nM |
143B |
Homo sapiens |
|
|
|
Toosendanin |
Western Blot |
Influence on EMT |
50.00 nM |
143B |
Homo sapiens |
|
|
|
Toosendanin |
Western Blot |
Influence on EMT |
100.00 nM |
143B |
Homo sapiens |
|
|
|
Toosendanin |
Western Blot |
Influence on EMT |
200.00 nM |
143B |
Homo sapiens |
|
|
|
Toosendanin |
Western Blot |
Influence on EMT |
50.00 nM |
MG63.2 |
Homo sapiens |
|
|
|
Toosendanin |
Western Blot |
Influence on EMT |
100.00 nM |
MG63.2 |
Homo sapiens |
|
|
|
Toosendanin |
Western Blot |
Influence on EMT |
200.00 nM |
MG63.2 |
Homo sapiens |
|
|
|
Toosendanin |
Western Blot |
Influence on EMT |
50.00 nM |
MG63.2 |
Homo sapiens |
|
|
|
Toosendanin |
Western Blot |
Influence on EMT |
100.00 nM |
MG63.2 |
Homo sapiens |
|
|
|
Toosendanin |
Western Blot |
Influence on EMT |
200.00 nM |
MG63.2 |
Homo sapiens |
|
|
|
Toosendanin |
Western Blot |
Influence on EMT |
50.00 nM |
MG63.2 |
Homo sapiens |
|
|
|
Toosendanin |
Western Blot |
Influence on EMT |
100.00 nM |
MG63.2 |
Homo sapiens |
|
|
|
Toosendanin |
Western Blot |
Influence on EMT |
200.00 nM |
MG63.2 |
Homo sapiens |
|
|
|
Toosendanin |
Western Blot |
Influence on EMT |
50.00 nM |
MG63.2 |
Homo sapiens |
|
|
|
Toosendanin |
Western Blot |
Influence on EMT |
100.00 nM |
MG63.2 |
Homo sapiens |
|
|
|
Toosendanin |
Western Blot |
Influence on EMT |
200.00 nM |
MG63.2 |
Homo sapiens |
|
|
|
Toosendanin |
Western Blot |
Influence on EMT |
50.00 nM |
MG63.2 |
Homo sapiens |
|
|
|
Toosendanin |
Western Blot |
Influence on EMT |
100.00 nM |
MG63.2 |
Homo sapiens |
|
|
|
Toosendanin |
Western Blot |
Influence on EMT |
200.00 nM |
MG63.2 |
Homo sapiens |
|
|
|
Toosendanin |
Tumor weight |
Influence on tumor growth |
1.00 mg/kg |
143B(xenograft) |
Mus musculus |
BALB/c |
|
|
Toosendanin |
Tumor weight |
Influence on tumor growth |
2.00 mg/kg |
143B(xenograft) |
Mus musculus |
BALB/c |
|
|
Toosendanin |
Number of metastasis nodules |
Influence on tumor growth |
2.00 mg/kg |
143B(xenograft) |
Mus musculus |
BALB/c |
|
|
Toosendanin |
Western Blot |
Influence on protien activity in tumor tissue |
1.00 mg/kg |
143B(xenograft) |
Mus musculus |
BALB/c |
p-STAT3 |
|
Toosendanin |
Western Blot |
Influence on protien activity in tumor tissue |
2.00 mg/kg |
143B(xenograft) |
Mus musculus |
BALB/c |
p-STAT3 |
|
Toosendanin |
Western Blot |
Influence on protien activity in tumor tissue |
1.00 mg/kg |
143B(xenograft) |
Mus musculus |
BALB/c |
STAT3 |
|
Toosendanin |
Western Blot |
Influence on protien activity in tumor tissue |
2.00 mg/kg |
143B(xenograft) |
Mus musculus |
BALB/c |
STAT3 |
|
Toosendanin |
Western Blot |
Influence on protien activity in tumor tissue |
1.00 mg/kg |
143B(xenograft) |
Mus musculus |
BALB/c |
|
|
Toosendanin |
Western Blot |
Influence on protien activity in tumor tissue |
2.00 mg/kg |
143B(xenograft) |
Mus musculus |
BALB/c |
|
|
Toosendanin |
Western Blot |
Influence on protien activity in tumor tissue |
1.00 mg/kg |
143B(xenograft) |
Mus musculus |
BALB/c |
|
|
Toosendanin |
Western Blot |
Influence on protien activity in tumor tissue |
2.00 mg/kg |
143B(xenograft) |
Mus musculus |
BALB/c |
|
|
Toosendanin |
Western Blot |
Influence on protien activity in tumor tissue |
1.00 mg/kg |
143B(xenograft) |
Mus musculus |
BALB/c |
|
|
Toosendanin |
Western Blot |
Influence on protien activity in tumor tissue |
2.00 mg/kg |
143B(xenograft) |
Mus musculus |
BALB/c |
|
|
Toosendanin |
Western Blot |
Influence on protien activity in tumor tissue |
1.00 mg/kg |
143B(xenograft) |
Mus musculus |
BALB/c |
|
|
Toosendanin |
Western Blot |
Influence on protien activity in tumor tissue |
2.00 mg/kg |
143B(xenograft) |
Mus musculus |
BALB/c |
|
|
Toosendanin |
Western Blot |
Influence on protien activity in tumor tissue |
1.00 mg/kg |
143B(xenograft) |
Mus musculus |
BALB/c |
|
|
Toosendanin |
Western Blot |
Influence on protien activity in tumor tissue |
2.00 mg/kg |
143B(xenograft) |
Mus musculus |
BALB/c |
|
|
Toosendanin |
Western Blot |
Influence on protien activity in tumor tissue |
1.00 mg/kg |
143B(xenograft) |
Mus musculus |
BALB/c |
|
|
Toosendanin |
Western Blot |
Influence on protien activity in tumor tissue |
2.00 mg/kg |
143B(xenograft) |
Mus musculus |
BALB/c |
|
|
Toosendanin |
Western Blot |
Influence on protien activity in tumor tissue |
1.00 mg/kg |
143B(patient derived xenograft) |
Mus musculus |
BALB/c |
p-STAT3 |
|
Toosendanin |
Western Blot |
Influence on protien activity in tumor tissue |
2.00 mg/kg |
143B(patient derived xenograft) |
Mus musculus |
BALB/c |
p-STAT3 |
|
Toosendanin |
Western Blot |
Influence on protien activity in tumor tissue |
1.00 mg/kg |
143B(patient derived xenograft) |
Mus musculus |
BALB/c |
STAT3 |
|
Toosendanin |
Western Blot |
Influence on protien activity in tumor tissue |
2.00 mg/kg |
143B(patient derived xenograft) |
Mus musculus |
BALB/c |
STAT3 |
|
Toosendanin |
Western Blot |
Influence on protien activity in tumor tissue |
1.00 mg/kg |
143B(patient derived xenograft) |
Mus musculus |
BALB/c |
|
|
Toosendanin |
Western Blot |
Influence on protien activity in tumor tissue |
2.00 mg/kg |
143B(patient derived xenograft) |
Mus musculus |
BALB/c |
|
|
Toosendanin |
Western Blot |
Influence on protien activity in tumor tissue |
1.00 mg/kg |
143B(patient derived xenograft) |
Mus musculus |
BALB/c |
|
|
Toosendanin |
Western Blot |
Influence on protien activity in tumor tissue |
2.00 mg/kg |
143B(patient derived xenograft) |
Mus musculus |
BALB/c |
|
|
Toosendanin |
Western Blot |
Influence on protien activity in tumor tissue |
1.00 mg/kg |
143B(patient derived xenograft) |
Mus musculus |
BALB/c |
|
|
Toosendanin |
Western Blot |
Influence on protien activity in tumor tissue |
2.00 mg/kg |
143B(patient derived xenograft) |
Mus musculus |
BALB/c |
|
|
Toosendanin |
Western Blot |
Influence on protien activity in tumor tissue |
1.00 mg/kg |
143B(patient derived xenograft) |
Mus musculus |
BALB/c |
|
|
Toosendanin |
Western Blot |
Influence on protien activity in tumor tissue |
2.00 mg/kg |
143B(patient derived xenograft) |
Mus musculus |
BALB/c |
|
|
Toosendanin |
Tumor weight |
Influence on tumor growth |
1.00 mg/kg |
143B(patient derived xenograft) |
Mus musculus |
BALB/c |
|
|
Toosendanin |
Tumor weight |
Influence on tumor growth |
2.00 mg/kg |
143B(patient derived xenograft) |
Mus musculus |
BALB/c |
|
|
Toosendanin |
MTS Assay |
Influence on cell viability |
100.00 nM |
HCT116 |
Homo sapiens |
|
|
|
Toosendanin |
MTS Assay |
Influence on cell viability |
200.00 nM |
HCT116 |
Homo sapiens |
|
|
|
Toosendanin |
MTS Assay |
Influence on cell viability |
100.00 nM |
SGC7901 |
Homo sapiens |
|
|
|
Toosendanin |
MTS Assay |
Influence on cell viability |
200.00 nM |
SGC7901 |
Homo sapiens |
|
|
|
Toosendanin |
MTS Assay |
Influence on cell viability |
100.00 nM |
SKOV3 |
Homo sapiens |
|
|
|
Toosendanin |
MTS Assay |
Influence on cell viability |
200.00 nM |
SKOV3 |
Homo sapiens |
|
|
|
Toosendanin |
MTS Assay |
Influence on cell viability |
100.00 nM |
MDA-MB-231 |
Homo sapiens |
|
|
|
Toosendanin |
MTS Assay |
Influence on cell viability |
200.00 nM |
MDA-MB-231 |
Homo sapiens |
|
|
|
Toosendanin |
MTS Assay |
Influence on cell viability |
100.00 nM |
DU145 |
Homo sapiens |
|
|
|
Toosendanin |
MTS Assay |
Influence on cell viability |
200.00 nM |
DU145 |
Homo sapiens |
|
|
|
Toosendanin |
MTS Assay |
Influence on cell viability |
100.00 nM |
Hela |
Homo sapiens |
|
|
|
Toosendanin |
MTS Assay |
Influence on cell viability |
200.00 nM |
Hela |
Homo sapiens |
|
|
|
Toosendanin |
MTS Assay |
Influence on cell viability |
100.00 nM |
SW-1990 |
Homo sapiens |
|
|
|
Toosendanin |
MTS Assay |
Influence on cell viability |
200.00 nM |
SW-1990 |
Homo sapiens |
|
|
|
Toosendanin |
Western Blot |
Influence on protein activity |
100.00 nM |
HCT116 |
Homo sapiens |
|
p-STAT3 |
|
Toosendanin |
Western Blot |
Influence on protein activity |
200.00 nM |
HCT116 |
Homo sapiens |
|
p-STAT3 |
|
Toosendanin |
Western Blot |
Influence on protein activity |
100.00 nM |
HCT116 |
Homo sapiens |
|
STAT3 |
|
Toosendanin |
Western Blot |
Influence on protein activity |
200.00 nM |
HCT116 |
Homo sapiens |
|
STAT3 |
|
Toosendanin |
Western Blot |
Influence on protein activity |
100.00 nM |
HCT116 |
Homo sapiens |
|
|
|
Toosendanin |
Western Blot |
Influence on protein activity |
200.00 nM |
HCT116 |
Homo sapiens |
|
|
|
Toosendanin |
Western Blot |
Influence on protein activity |
100.00 nM |
SGC7901 |
Homo sapiens |
|
p-STAT3 |
|
Toosendanin |
Western Blot |
Influence on protein activity |
200.00 nM |
SGC7901 |
Homo sapiens |
|
p-STAT3 |
|
Toosendanin |
Western Blot |
Influence on protein activity |
100.00 nM |
SGC7901 |
Homo sapiens |
|
STAT3 |
|
Toosendanin |
Western Blot |
Influence on protein activity |
200.00 nM |
SGC7901 |
Homo sapiens |
|
STAT3 |
|
Toosendanin |
Western Blot |
Influence on protein activity |
100.00 nM |
SGC7901 |
Homo sapiens |
|
|
|
Toosendanin |
Western Blot |
Influence on protein activity |
200.00 nM |
SGC7901 |
Homo sapiens |
|
|
|
Toosendanin |
Western Blot |
Influence on protein activity |
100.00 nM |
SKOV3 |
Homo sapiens |
|
p-STAT3 |
|
Toosendanin |
Western Blot |
Influence on protein activity |
200.00 nM |
SKOV3 |
Homo sapiens |
|
p-STAT3 |
|
Toosendanin |
Western Blot |
Influence on protein activity |
100.00 nM |
SKOV3 |
Homo sapiens |
|
STAT3 |
|
Toosendanin |
Western Blot |
Influence on protein activity |
200.00 nM |
SKOV3 |
Homo sapiens |
|
STAT3 |
|
Toosendanin |
Western Blot |
Influence on protein activity |
100.00 nM |
SKOV3 |
Homo sapiens |
|
|
|
Toosendanin |
Western Blot |
Influence on protein activity |
200.00 nM |
SKOV3 |
Homo sapiens |
|
|
|
Toosendanin |
Western Blot |
Influence on protein activity |
100.00 nM |
MDA-MB-231 |
Homo sapiens |
|
p-STAT3 |
|
Toosendanin |
Western Blot |
Influence on protein activity |
200.00 nM |
MDA-MB-231 |
Homo sapiens |
|
p-STAT3 |
|
Toosendanin |
Western Blot |
Influence on protein activity |
100.00 nM |
MDA-MB-231 |
Homo sapiens |
|
STAT3 |
|
Toosendanin |
Western Blot |
Influence on protein activity |
200.00 nM |
MDA-MB-231 |
Homo sapiens |
|
STAT3 |
|
Toosendanin |
Western Blot |
Influence on protein activity |
100.00 nM |
MDA-MB-231 |
Homo sapiens |
|
|
|
Toosendanin |
Western Blot |
Influence on protein activity |
200.00 nM |
MDA-MB-231 |
Homo sapiens |
|
|
|
Toosendanin |
Western Blot |
Influence on protein activity |
100.00 nM |
DU145 |
Homo sapiens |
|
p-STAT3 |
|
Toosendanin |
Western Blot |
Influence on protein activity |
200.00 nM |
DU145 |
Homo sapiens |
|
p-STAT3 |
|
Toosendanin |
Western Blot |
Influence on protein activity |
100.00 nM |
DU145 |
Homo sapiens |
|
STAT3 |
|
Toosendanin |
Western Blot |
Influence on protein activity |
200.00 nM |
DU145 |
Homo sapiens |
|
STAT3 |
|
Toosendanin |
Western Blot |
Influence on protein activity |
100.00 nM |
DU145 |
Homo sapiens |
|
|
|
Toosendanin |
Western Blot |
Influence on protein activity |
200.00 nM |
DU145 |
Homo sapiens |
|
|
|
Toosendanin |
Western Blot |
Influence on protein activity |
100.00 nM |
Hela |
Homo sapiens |
|
p-STAT3 |
|
Toosendanin |
Western Blot |
Influence on protein activity |
200.00 nM |
Hela |
Homo sapiens |
|
p-STAT3 |
|
Toosendanin |
Western Blot |
Influence on protein activity |
100.00 nM |
Hela |
Homo sapiens |
|
STAT3 |
|
Toosendanin |
Western Blot |
Influence on protein activity |
200.00 nM |
Hela |
Homo sapiens |
|
STAT3 |
|
Toosendanin |
Western Blot |
Influence on protein activity |
100.00 nM |
Hela |
Homo sapiens |
|
|
|
Toosendanin |
Western Blot |
Influence on protein activity |
200.00 nM |
Hela |
Homo sapiens |
|
|
|
Toosendanin |
Western Blot |
Influence on protein activity |
100.00 nM |
SW-1990 |
Homo sapiens |
|
p-STAT3 |
|
Toosendanin |
Western Blot |
Influence on protein activity |
200.00 nM |
SW-1990 |
Homo sapiens |
|
p-STAT3 |
|
Toosendanin |
Western Blot |
Influence on protein activity |
100.00 nM |
SW-1990 |
Homo sapiens |
|
STAT3 |
|
Toosendanin |
Western Blot |
Influence on protein activity |
200.00 nM |
SW-1990 |
Homo sapiens |
|
STAT3 |
|
Toosendanin |
Western Blot |
Influence on protein activity |
100.00 nM |
SW-1990 |
Homo sapiens |
|
|
|
Toosendanin |
Western Blot |
Influence on protein activity |
200.00 nM |
SW-1990 |
Homo sapiens |
|
|
|