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Experiments

Compound Investigated event Experiment type Concentration Cell line Organism Animal model Stat protein Details
Toosendanin Influence on protien activity in tumor tissue Western Blot 1.00 mg/kg 143B(xenograft) Mus musculus BALB/c p-STAT3
Toosendanin Influence on protien activity in tumor tissue Western Blot 2.00 mg/kg 143B(xenograft) Mus musculus BALB/c p-STAT3
Toosendanin Influence on protien activity in tumor tissue Western Blot 1.00 mg/kg 143B(patient derived xenograft) Mus musculus BALB/c p-STAT3
Toosendanin Influence on protien activity in tumor tissue Western Blot 2.00 mg/kg 143B(patient derived xenograft) Mus musculus BALB/c p-STAT3
Toosendanin Influence on protein activity Western Blot 100.00 nM HCT116 Homo sapiens p-STAT3
Toosendanin Influence on protein activity Western Blot 200.00 nM HCT116 Homo sapiens p-STAT3
Toosendanin Influence on protein activity Western Blot 100.00 nM SGC7901 Homo sapiens p-STAT3
Toosendanin Influence on protein activity Western Blot 200.00 nM SGC7901 Homo sapiens p-STAT3
Toosendanin Influence on protein activity Western Blot 100.00 nM SKOV3 Homo sapiens p-STAT3
Toosendanin Influence on protein activity Western Blot 200.00 nM SKOV3 Homo sapiens p-STAT3
Toosendanin Influence on protein activity Western Blot 100.00 nM MDA-MB-231 Homo sapiens p-STAT3
Toosendanin Influence on protein activity Western Blot 200.00 nM MDA-MB-231 Homo sapiens p-STAT3
Toosendanin Influence on protein activity Western Blot 100.00 nM DU145 Homo sapiens p-STAT3
Toosendanin Influence on protein activity Western Blot 200.00 nM DU145 Homo sapiens p-STAT3
Toosendanin Influence on protein activity Western Blot 100.00 nM Hela Homo sapiens p-STAT3
Toosendanin Influence on protein activity Western Blot 200.00 nM Hela Homo sapiens p-STAT3
Toosendanin Influence on protein activity Western Blot 100.00 nM SW-1990 Homo sapiens p-STAT3
Toosendanin Influence on protein activity Western Blot 200.00 nM SW-1990 Homo sapiens p-STAT3
Toosendanin Influence on protein activity Western Blot 50.00 nM 143B Homo sapiens STAT3
Toosendanin Influence on protein activity Western Blot 100.00 nM 143B Homo sapiens STAT3
Toosendanin Influence on protein activity Western Blot 200.00 nM 143B Homo sapiens STAT3
Toosendanin Influence on protein activity Western Blot 50.00 nM HOS Homo sapiens STAT3
Toosendanin Influence on protein activity Western Blot 100.00 nM HOS Homo sapiens STAT3
Toosendanin Influence on protein activity Western Blot 200.00 nM HOS Homo sapiens STAT3
Toosendanin Influence on protein activity Western Blot 50.00 nM MG63.2 Homo sapiens STAT3
Toosendanin Influence on protein activity Western Blot 100.00 nM MG63.2 Homo sapiens STAT3
Toosendanin Influence on protein activity Western Blot 200.00 nM MG63.2 Homo sapiens STAT3
Toosendanin Influence on protein activity in presence of IL-6 Immunofluorescence 100.00 nM 143B Homo sapiens STAT3
Toosendanin Influence on protein-DNA interaction EMSA 50.00 nM 143B Homo sapiens STAT3
Toosendanin Influence on protein-DNA interaction EMSA 100.00 nM 143B Homo sapiens STAT3
Toosendanin Influence on protein-DNA interaction EMSA 200.00 nM 143B Homo sapiens STAT3
Toosendanin Influence on protien activity in tumor tissue Western Blot 1.00 mg/kg 143B(xenograft) Mus musculus BALB/c STAT3
Toosendanin Influence on protien activity in tumor tissue Western Blot 2.00 mg/kg 143B(xenograft) Mus musculus BALB/c STAT3
Toosendanin Influence on protien activity in tumor tissue Western Blot 1.00 mg/kg 143B(patient derived xenograft) Mus musculus BALB/c STAT3
Toosendanin Influence on protien activity in tumor tissue Western Blot 2.00 mg/kg 143B(patient derived xenograft) Mus musculus BALB/c STAT3
Toosendanin Influence on protein activity Western Blot 100.00 nM HCT116 Homo sapiens STAT3
Toosendanin Influence on protein activity Western Blot 200.00 nM HCT116 Homo sapiens STAT3
Toosendanin Influence on protein activity Western Blot 100.00 nM SGC7901 Homo sapiens STAT3
Toosendanin Influence on protein activity Western Blot 200.00 nM SGC7901 Homo sapiens STAT3
Toosendanin Influence on protein activity Western Blot 100.00 nM SKOV3 Homo sapiens STAT3
Toosendanin Influence on protein activity Western Blot 200.00 nM SKOV3 Homo sapiens STAT3
Toosendanin Influence on protein activity Western Blot 100.00 nM MDA-MB-231 Homo sapiens STAT3
Toosendanin Influence on protein activity Western Blot 200.00 nM MDA-MB-231 Homo sapiens STAT3
Toosendanin Influence on protein activity Western Blot 100.00 nM DU145 Homo sapiens STAT3
Toosendanin Influence on protein activity Western Blot 200.00 nM DU145 Homo sapiens STAT3
Toosendanin Influence on protein activity Western Blot 100.00 nM Hela Homo sapiens STAT3
Toosendanin Influence on protein activity Western Blot 200.00 nM Hela Homo sapiens STAT3
Toosendanin Influence on protein activity Western Blot 100.00 nM SW-1990 Homo sapiens STAT3
Toosendanin Influence on protein activity Western Blot 200.00 nM SW-1990 Homo sapiens STAT3
Toosendanin Influence on protein activity Western Blot 50.00 nM 143B Homo sapiens p-STAT3(Y705)