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Experiments

Compound Investigated event Experiment type Concentration Cell line Organism Animal model Stat protein Details
Toosendanin Influence on protein activity Luciferase reporter assay 25.00 nM 143B Homo sapiens
Toosendanin Influence on protein activity Luciferase reporter assay 50.00 nM 143B Homo sapiens
Toosendanin Influence on protein activity Luciferase reporter assay 100.00 nM 143B Homo sapiens
Toosendanin Influence on protein activity Western Blot 50.00 nM 143B Homo sapiens p-STAT3(Y705)
Toosendanin Influence on protein activity Western Blot 100.00 nM 143B Homo sapiens p-STAT3(Y705)
Toosendanin Influence on protein activity Western Blot 200.00 nM 143B Homo sapiens p-STAT3(Y705)
Toosendanin Influence on protein activity Western Blot 50.00 nM 143B Homo sapiens p-STAT3(S727)
Toosendanin Influence on protein activity Western Blot 100.00 nM 143B Homo sapiens p-STAT3(S727)
Toosendanin Influence on protein activity Western Blot 200.00 nM 143B Homo sapiens p-STAT3(S727)
Toosendanin Influence on protein activity Western Blot 50.00 nM 143B Homo sapiens STAT3
Toosendanin Influence on protein activity Western Blot 100.00 nM 143B Homo sapiens STAT3
Toosendanin Influence on protein activity Western Blot 200.00 nM 143B Homo sapiens STAT3
Toosendanin Influence on protein activity Western Blot 50.00 nM 143B Homo sapiens
Toosendanin Influence on protein activity Western Blot 100.00 nM 143B Homo sapiens
Toosendanin Influence on protein activity Western Blot 200.00 nM 143B Homo sapiens
Toosendanin Influence on protein activity in presence of IL-6 Immunofluorescence 100.00 nM 143B Homo sapiens STAT3
Toosendanin Influence on protein translocation in presence of IL-6 Western Blot 50.00 nM 143B Homo sapiens STAT3(nucleus)
Toosendanin Influence on protein translocation in presence of IL-6 Western Blot 100.00 nM 143B Homo sapiens STAT3(nucleus)
Toosendanin Influence on protein translocation in presence of IL-6 Western Blot 50.00 nM 143B Homo sapiens
Toosendanin Influence on protein translocation in presence of IL-6 Western Blot 100.00 nM 143B Homo sapiens
Toosendanin Influence on protein translocation in presence of IL-6 Western Blot 50.00 nM 143B Homo sapiens
Toosendanin Influence on protein translocation in presence of IL-6 Western Blot 100.00 nM 143B Homo sapiens
Toosendanin Influence on protein translocation in presence of IL-6 Western Blot 50.00 nM 143B Homo sapiens STAT3(cytoplasm)
Toosendanin Influence on protein translocation in presence of IL-6 Western Blot 100.00 nM 143B Homo sapiens STAT3(cytoplasm)
Toosendanin Influence on protein translocation in presence of IL-6 Western Blot 50.00 nM 143B Homo sapiens
Toosendanin Influence on protein translocation in presence of IL-6 Western Blot 100.00 nM 143B Homo sapiens
Toosendanin Influence on protein translocation in presence of IL-6 Western Blot 50.00 nM 143B Homo sapiens
Toosendanin Influence on protein translocation in presence of IL-6 Western Blot 100.00 nM 143B Homo sapiens
Toosendanin Influence on protein-DNA interaction EMSA 50.00 nM 143B Homo sapiens STAT3
Toosendanin Influence on protein-DNA interaction EMSA 100.00 nM 143B Homo sapiens STAT3
Toosendanin Influence on protein-DNA interaction EMSA 200.00 nM 143B Homo sapiens STAT3
Toosendanin Influence on expression of STAT3 target genes RT-PCR 50.00 nM 143B Homo sapiens
Toosendanin Influence on expression of STAT3 target genes RT-PCR 100.00 nM 143B Homo sapiens
Toosendanin Influence on expression of STAT3 target genes RT-PCR 200.00 nM 143B Homo sapiens
Toosendanin Influence on expression of STAT3 target genes RT-PCR 50.00 nM 143B Homo sapiens
Toosendanin Influence on expression of STAT3 target genes RT-PCR 100.00 nM 143B Homo sapiens
Toosendanin Influence on expression of STAT3 target genes RT-PCR 200.00 nM 143B Homo sapiens
Toosendanin Influence on expression of STAT3 target genes RT-PCR 50.00 nM 143B Homo sapiens
Toosendanin Influence on expression of STAT3 target genes RT-PCR 100.00 nM 143B Homo sapiens
Toosendanin Influence on expression of STAT3 target genes RT-PCR 200.00 nM 143B Homo sapiens
Toosendanin Influence on expression of STAT3 target genes RT-PCR 50.00 nM 143B Homo sapiens
Toosendanin Influence on expression of STAT3 target genes RT-PCR 100.00 nM 143B Homo sapiens
Toosendanin Influence on expression of STAT3 target genes RT-PCR 200.00 nM 143B Homo sapiens
Toosendanin Influence on expression of STAT3 target genes RT-PCR 50.00 nM 143B Homo sapiens
Toosendanin Influence on expression of STAT3 target genes RT-PCR 100.00 nM 143B Homo sapiens
Toosendanin Influence on expression of STAT3 target genes RT-PCR 200.00 nM 143B Homo sapiens
Toosendanin Influence on expression of STAT3 target genes RT-PCR 50.00 nM 143B Homo sapiens
Toosendanin Influence on expression of STAT3 target genes RT-PCR 100.00 nM 143B Homo sapiens
Toosendanin Influence on expression of STAT3 target genes RT-PCR 200.00 nM 143B Homo sapiens
Toosendanin Influence on expression of STAT3 target genes RT-PCR 50.00 nM 143B Homo sapiens