LLL-12 |
Western Blot |
Influence on protein activity |
5.00 µM |
MDA-MB-231 |
Homo sapiens |
|
p-STAT3 (Y705) |
|
LLL-12 |
Western Blot |
Influence on protein activity |
5.00 µM |
MDA-MB-231 |
Homo sapiens |
|
STAT3 |
|
LLL-12 |
Western Blot |
Influence on protein activity |
5.00 µM |
MDA-MB-231 |
Homo sapiens |
|
|
|
LLL-12 |
Western Blot |
Influence on protein activity |
5.00 µM |
MDA-MB-231 |
Homo sapiens |
|
|
|
LLL-12 |
Western Blot |
Influence on protein activity |
5.00 µM |
MDA-MB-231 |
Homo sapiens |
|
|
|
LLL-12 |
Western Blot |
Influence on protein activity |
5.00 µM |
MDA-MB-231 |
Homo sapiens |
|
|
|
LLL-12 |
Western Blot |
Influence on protein activity |
5.00 µM |
MDA-MB-231 |
Homo sapiens |
|
|
|
LLL-12 |
Western Blot |
Influence on protein activity |
5.00 µM |
MDA-MB-231 |
Homo sapiens |
|
|
|
LLL-12 |
Western Blot |
Influence on protein activity |
5.00 µM |
MDA-MB-231 |
Homo sapiens |
|
|
|
LLL-12 |
Western Blot |
Influence on protein activity |
5.00 µM |
MDA-MB-231 |
Homo sapiens |
|
|
|
LLL-12 |
Western Blot |
Influence on protein activity |
5.00 µM |
MDA-MB-231 |
Homo sapiens |
|
|
|
LLL-12 |
Western Blot |
Influence on protein activity |
5.00 µM |
MDA-MB-231 |
Homo sapiens |
|
|
|
LLL-12 |
Western Blot |
Influence on protein activity |
5.00 µM |
SK-BR-3 |
Homo sapiens |
|
p-STAT3 (Y705) |
|
LLL-12 |
Western Blot |
Influence on protein activity |
5.00 µM |
SK-BR-3 |
Homo sapiens |
|
STAT3 |
|
LLL-12 |
Western Blot |
Influence on protein activity |
5.00 µM |
SK-BR-3 |
Homo sapiens |
|
|
|
LLL-12 |
Western Blot |
Influence on protein activity |
5.00 µM |
SK-BR-3 |
Homo sapiens |
|
|
|
LLL-12 |
Western Blot |
Influence on protein activity |
5.00 µM |
SK-BR-3 |
Homo sapiens |
|
|
|
LLL-12 |
Western Blot |
Influence on protein activity |
5.00 µM |
SK-BR-3 |
Homo sapiens |
|
|
|
LLL-12 |
Western Blot |
Influence on protein activity |
5.00 µM |
SK-BR-3 |
Homo sapiens |
|
|
|
LLL-12 |
Western Blot |
Influence on protein activity |
5.00 µM |
SK-BR-3 |
Homo sapiens |
|
|
|
LLL-12 |
Western Blot |
Influence on protein activity |
5.00 µM |
SK-BR-3 |
Homo sapiens |
|
|
|
LLL-12 |
Western Blot |
Influence on protein activity |
5.00 µM |
SK-BR-3 |
Homo sapiens |
|
|
|
LLL-12 |
Western Blot |
Influence on protein activity |
5.00 µM |
SK-BR-3 |
Homo sapiens |
|
|
|
LLL-12 |
Western Blot |
Influence on protein activity |
5.00 µM |
SK-BR-3 |
Homo sapiens |
|
|
|
LLL-12 |
Western Blot |
Influence on protein activity |
5.00 µM |
HPAC |
Homo sapiens |
|
p-STAT3 (Y705) |
|
LLL-12 |
Western Blot |
Influence on protein activity |
5.00 µM |
HPAC |
Homo sapiens |
|
STAT3 |
|
LLL-12 |
Western Blot |
Influence on protein activity |
5.00 µM |
HPAC |
Homo sapiens |
|
|
|
LLL-12 |
Western Blot |
Influence on protein activity |
5.00 µM |
HPAC |
Homo sapiens |
|
|
|
LLL-12 |
Western Blot |
Influence on protein activity |
5.00 µM |
HPAC |
Homo sapiens |
|
|
|
LLL-12 |
Western Blot |
Influence on protein activity |
5.00 µM |
HPAC |
Homo sapiens |
|
|
|
LLL-12 |
Western Blot |
Influence on protein activity |
5.00 µM |
HPAC |
Homo sapiens |
|
|
|
LLL-12 |
Western Blot |
Influence on protein activity |
5.00 µM |
HPAC |
Homo sapiens |
|
|
|
LLL-12 |
Western Blot |
Influence on protein activity |
5.00 µM |
HPAC |
Homo sapiens |
|
|
|
LLL-12 |
Western Blot |
Influence on protein activity |
5.00 µM |
HPAC |
Homo sapiens |
|
|
|
LLL-12 |
Western Blot |
Influence on protein activity |
5.00 µM |
HPAC |
Homo sapiens |
|
|
|
LLL-12 |
Western Blot |
Influence on protein activity |
10.00 µM |
U87 |
Homo sapiens |
|
p-STAT3 (Y705) |
|
LLL-12 |
Western Blot |
Influence on protein activity |
10.00 µM |
U87 |
Homo sapiens |
|
STAT3 |
|
LLL-12 |
Western Blot |
Influence on protein activity |
10.00 µM |
U87 |
Homo sapiens |
|
|
|
LLL-12 |
Western Blot |
Influence on protein activity |
10.00 µM |
U87 |
Homo sapiens |
|
|
|
LLL-12 |
Western Blot |
Influence on protein activity |
10.00 µM |
U87 |
Homo sapiens |
|
|
|
LLL-12 |
Western Blot |
Influence on protein activity |
10.00 µM |
U87 |
Homo sapiens |
|
|
|
LLL-12 |
Western Blot |
Influence on protein activity |
10.00 µM |
U87 |
Homo sapiens |
|
|
|
LLL-12 |
Western Blot |
Influence on protein activity |
10.00 µM |
U87 |
Homo sapiens |
|
|
|
LLL-12 |
Western Blot |
Influence on protein activity |
5.00 µM |
HPDE |
Homo sapiens |
|
|
|
LLL-12 |
Western Blot |
Influence on protein activity |
5.00 µM |
HMEC |
Homo sapiens |
|
|
|
LLL-12 |
Western Blot |
Influence on protein activity |
5.00 µM |
HPDE |
Homo sapiens |
|
|
|
LLL-12 |
Western Blot |
Influence on protein activity |
5.00 µM |
HMEC |
Homo sapiens |
|
|
|
LLL-12 |
Western Blot |
Influence on protein activity |
5.00 µM |
HPDE |
Homo sapiens |
|
|
|
LLL-12 |
Western Blot |
Influence on protein activity |
5.00 µM |
HMEC |
Homo sapiens |
|
|
|
LLL-12 |
Western Blot |
Influence on protein activity |
5.00 µM |
HH |
Homo sapiens |
|
|
|
LLL-12 |
Western Blot |
Influence on protein activity |
5.00 µM |
HH |
Homo sapiens |
|
|
|
LLL-12 |
Western Blot |
Influence on protein activity |
5.00 µM |
HH |
Homo sapiens |
|
|
|
LLL-12 |
Western Blot |
Influence on protein activity |
5.00 µM |
WI-38 |
Homo sapiens |
|
|
|
LLL-12 |
Western Blot |
Influence on protein activity |
10.00 µM |
WI-38 |
Homo sapiens |
|
|
|
LLL-12 |
Western Blot |
Influence on protein activity |
5.00 µM |
WI-38 |
Homo sapiens |
|
|
|
LLL-12 |
Western Blot |
Influence on protein activity |
10.00 µM |
WI-38 |
Homo sapiens |
|
|
|
LLL-12 |
Western Blot |
Influence on protein activity |
5.00 µM |
WI-38 |
Homo sapiens |
|
|
|
LLL-12 |
Western Blot |
Influence on protein activity |
10.00 µM |
WI-38 |
Homo sapiens |
|
|
|
LLL-12 |
Western Blot |
Influence on protein activity in presence of IL-6 |
0.50 µM |
MDA-MB-453 |
Homo sapiens |
|
p-STAT3 (Y705) |
|
LLL-12 |
Western Blot |
Influence on protein activity in presence of IL-6 |
1.00 µM |
MDA-MB-453 |
Homo sapiens |
|
p-STAT3 (Y705) |
|
LLL-12 |
Western Blot |
Influence on protein activity in presence of IL-6 |
2.00 µM |
MDA-MB-453 |
Homo sapiens |
|
p-STAT3 (Y705) |
|
LLL-12 |
Western Blot |
Influence on protein activity in presence of IL-6 |
0.50 µM |
MDA-MB-453 |
Homo sapiens |
|
STAT3 |
|
LLL-12 |
Western Blot |
Influence on protein activity in presence of IL-6 |
1.00 µM |
MDA-MB-453 |
Homo sapiens |
|
STAT3 |
|
LLL-12 |
Western Blot |
Influence on protein activity in presence of IL-6 |
2.00 µM |
MDA-MB-453 |
Homo sapiens |
|
STAT3 |
|
LLL-12 |
Western Blot |
Influence on protein activity in presence of IL-6 |
0.50 µM |
MDA-MB-453 |
Homo sapiens |
|
|
|
LLL-12 |
Western Blot |
Influence on protein activity in presence of IL-6 |
1.00 µM |
MDA-MB-453 |
Homo sapiens |
|
|
|
LLL-12 |
Western Blot |
Influence on protein activity in presence of IL-6 |
2.00 µM |
MDA-MB-453 |
Homo sapiens |
|
|
|
LLL-12 |
ELISA |
Influence on protein binding to DNA |
10.00 µM |
SK-BR-3 |
Homo sapiens |
|
STAT1 |
|
LLL-12 |
ELISA |
Influence on protein binding to DNA |
10.00 µM |
MDA-MB-453 |
Homo sapiens |
|
STAT1 |
|
LLL-12 |
ELISA |
Influence on protein binding to DNA |
10.00 µM |
HPAC |
Homo sapiens |
|
STAT1 |
|
LLL-12 |
ELISA |
Influence on protein binding to DNA |
10.00 µM |
U87 |
Homo sapiens |
|
STAT1 |
|
LLL-12 |
ELISA |
Influence on protein binding to DNA |
10.00 µM |
SK-BR-3 |
Homo sapiens |
|
STAT3 |
|
LLL-12 |
ELISA |
Influence on protein binding to DNA |
10.00 µM |
MDA-MB-453 |
Homo sapiens |
|
STAT3 |
|
LLL-12 |
ELISA |
Influence on protein binding to DNA |
10.00 µM |
HPAC |
Homo sapiens |
|
STAT3 |
|
LLL-12 |
ELISA |
Influence on protein binding to DNA |
10.00 µM |
U87 |
Homo sapiens |
|
STAT3 |
|
LLL-12 |
Luciferase Assay |
Influence on protein activity |
1.00 µM |
MDA-MB-231 |
Homo sapiens |
|
STAT3 |
|
LLL-12 |
Luciferase Assay |
Influence on protein activity |
2.50 µM |
MDA-MB-231 |
Homo sapiens |
|
STAT3 |
|
LLL-12 |
Luciferase Assay |
Influence on protein activity |
5.00 µM |
MDA-MB-231 |
Homo sapiens |
|
STAT3 |
|
LLL-12 |
Luciferase Assay |
Influence on protein activity |
10.00 µM |
MDA-MB-231 |
Homo sapiens |
|
STAT3 |
|
LLL-12 |
RT-PCR |
Influence on gene expression |
5.00 µM |
MDA-MB-231 |
Homo sapiens |
|
|
|
LLL-12 |
RT-PCR |
Influence on gene expression |
10.00 µM |
MDA-MB-231 |
Homo sapiens |
|
|
|
LLL-12 |
RT-PCR |
Influence on gene expression |
5.00 µM |
MDA-MB-231 |
Homo sapiens |
|
|
|
LLL-12 |
RT-PCR |
Influence on gene expression |
10.00 µM |
MDA-MB-231 |
Homo sapiens |
|
|
|
LLL-12 |
RT-PCR |
Influence on gene expression |
5.00 µM |
MDA-MB-231 |
Homo sapiens |
|
|
|
LLL-12 |
RT-PCR |
Influence on gene expression |
10.00 µM |
MDA-MB-231 |
Homo sapiens |
|
|
|
LLL-12 |
RT-PCR |
Influence on gene expression |
5.00 µM |
MDA-MB-231 |
Homo sapiens |
|
|
|
LLL-12 |
RT-PCR |
Influence on gene expression |
10.00 µM |
MDA-MB-231 |
Homo sapiens |
|
|
|
LLL-12 |
RT-PCR |
Influence on gene expression |
5.00 µM |
MDA-MB-231 |
Homo sapiens |
|
|
|
LLL-12 |
RT-PCR |
Influence on gene expression |
10.00 µM |
MDA-MB-231 |
Homo sapiens |
|
|
|
LLL-12 |
RT-PCR |
Influence on gene expression |
10.00 µM |
HPAC |
Homo sapiens |
|
|
|
LLL-12 |
RT-PCR |
Influence on gene expression |
10.00 µM |
HPAC |
Homo sapiens |
|
|
|
LLL-12 |
RT-PCR |
Influence on gene expression |
10.00 µM |
HPAC |
Homo sapiens |
|
|
|
LLL-12 |
RT-PCR |
Influence on gene expression |
10.00 µM |
HPAC |
Homo sapiens |
|
|
|
LLL-12 |
RT-PCR |
Influence on gene expression |
10.00 µM |
U373 |
Homo sapiens |
|
|
|
LLL-12 |
RT-PCR |
Influence on gene expression |
10.00 µM |
U373 |
Homo sapiens |
|
|
|
LLL-12 |
RT-PCR |
Influence on gene expression |
10.00 µM |
U373 |
Homo sapiens |
|
|
|
LLL-12 |
RT-PCR |
Influence on gene expression |
10.00 µM |
U373 |
Homo sapiens |
|
|
|
LLL-12 |
Colony formation assay |
Influence on cell proliferation |
1.00 µM |
MDA-MB-231 |
Homo sapiens |
|
|
|
LLL-12 |
Colony formation assay |
Influence on cell proliferation |
5.00 µM |
MDA-MB-231 |
Homo sapiens |
|
|
|
LLL-12 |
Wound healing assay |
Influence on cell proliferation |
1.00 µM |
MDA-MB-231 |
Homo sapiens |
|
|
|
LLL-12 |
Wound healing assay |
Influence on cell proliferation |
2.50 µM |
MDA-MB-231 |
Homo sapiens |
|
|
|
LLL-12 |
Wound healing assay |
Influence on cell proliferation |
5.00 µM |
MDA-MB-231 |
Homo sapiens |
|
|
|
LLL-12 |
Wound healing assay |
Influence on cell proliferation |
10.00 µM |
MDA-MB-231 |
Homo sapiens |
|
|
|
LLL-12 |
Wound healing assay |
Influence on cell proliferation |
20.00 µM |
MDA-MB-231 |
Homo sapiens |
|
|
|
LLL-12 |
MTT |
Influence on cell viability |
1.00 µM |
MDA-MB-231 |
Homo sapiens |
|
|
|
LLL-12 |
MTT |
Influence on cell viability |
2.50 µM |
MDA-MB-231 |
Homo sapiens |
|
|
|
LLL-12 |
MTT |
Influence on cell viability |
5.00 µM |
MDA-MB-231 |
Homo sapiens |
|
|
|
LLL-12 |
MTT |
Influence on cell viability |
10.00 µM |
MDA-MB-231 |
Homo sapiens |
|
|
|
LLL-12 |
MTT |
Influence on cell viability |
20.00 µM |
MDA-MB-231 |
Homo sapiens |
|
|
|
LLL-12 |
Western Blot |
Influence on protein activity |
1.00 µM |
U87 |
Homo sapiens |
|
p-STAT3 (Y705) |
|
LLL-12 |
Western Blot |
Influence on protein activity |
2.50 µM |
U87 |
Homo sapiens |
|
p-STAT3 (Y705) |
|
LLL-12 |
Western Blot |
Influence on protein activity |
5.00 µM |
U87 |
Homo sapiens |
|
p-STAT3 (Y705) |
|
LLL-12 |
Western Blot |
Influence on protein activity |
1.00 µM |
U87 |
Homo sapiens |
|
STAT3 |
|
LLL-12 |
Western Blot |
Influence on protein activity |
2.50 µM |
U87 |
Homo sapiens |
|
STAT3 |
|
LLL-12 |
Western Blot |
Influence on protein activity |
5.00 µM |
U87 |
Homo sapiens |
|
STAT3 |
|
LLL-12 |
Western Blot |
Influence on protein activity |
1.00 µM |
U87 |
Homo sapiens |
|
|
|
LLL-12 |
Western Blot |
Influence on protein activity |
2.50 µM |
U87 |
Homo sapiens |
|
|
|
LLL-12 |
Western Blot |
Influence on protein activity |
5.00 µM |
U87 |
Homo sapiens |
|
|
|
LLL-12 |
Western Blot |
Influence on protein activity |
1.00 µM |
U87 |
Homo sapiens |
|
|
|
LLL-12 |
Western Blot |
Influence on protein activity |
2.50 µM |
U87 |
Homo sapiens |
|
|
|
LLL-12 |
Western Blot |
Influence on protein activity |
5.00 µM |
U87 |
Homo sapiens |
|
|
|
LLL-12 |
Western Blot |
Influence on protein activity |
1.00 µM |
U87 |
Homo sapiens |
|
|
|
LLL-12 |
Western Blot |
Influence on protein activity |
2.50 µM |
U87 |
Homo sapiens |
|
|
|
LLL-12 |
Western Blot |
Influence on protein activity |
5.00 µM |
U87 |
Homo sapiens |
|
|
|
LLL-12 |
Western Blot |
Influence on protein activity in STAT3 transfected cells |
1.00 µM |
U87 |
Homo sapiens |
|
p-STAT3 (Y705) |
|
LLL-12 |
Western Blot |
Influence on protein activity in STAT3 transfected cells |
2.50 µM |
U87 |
Homo sapiens |
|
p-STAT3 (Y705) |
|
LLL-12 |
Western Blot |
Influence on protein activity in STAT3 transfected cells |
5.00 µM |
U87 |
Homo sapiens |
|
p-STAT3 (Y705) |
|
LLL-12 |
Western Blot |
Influence on protein activity in STAT3 transfected cells |
1.00 µM |
U87 |
Homo sapiens |
|
STAT3 |
|
LLL-12 |
Western Blot |
Influence on protein activity in STAT3 transfected cells |
2.50 µM |
U87 |
Homo sapiens |
|
STAT3 |
|
LLL-12 |
Western Blot |
Influence on protein activity in STAT3 transfected cells |
5.00 µM |
U87 |
Homo sapiens |
|
STAT3 |
|
LLL-12 |
Western Blot |
Influence on protein activity in STAT3 transfected cells |
1.00 µM |
U87 |
Homo sapiens |
|
|
|
LLL-12 |
Western Blot |
Influence on protein activity in STAT3 transfected cells |
2.50 µM |
U87 |
Homo sapiens |
|
|
|
LLL-12 |
Western Blot |
Influence on protein activity in STAT3 transfected cells |
5.00 µM |
U87 |
Homo sapiens |
|
|
|
LLL-12 |
Western Blot |
Influence on protein activity in STAT3 transfected cells |
1.00 µM |
U87 |
Homo sapiens |
|
|
|
LLL-12 |
Western Blot |
Influence on protein activity in STAT3 transfected cells |
2.50 µM |
U87 |
Homo sapiens |
|
|
|
LLL-12 |
Western Blot |
Influence on protein activity in STAT3 transfected cells |
5.00 µM |
U87 |
Homo sapiens |
|
|
|
LLL-12 |
Western Blot |
Influence on protein activity in STAT3 transfected cells |
1.00 µM |
U87 |
Homo sapiens |
|
|
|
LLL-12 |
Western Blot |
Influence on protein activity in STAT3 transfected cells |
2.50 µM |
U87 |
Homo sapiens |
|
|
|
LLL-12 |
Western Blot |
Influence on protein activity in STAT3 transfected cells |
5.00 µM |
U87 |
Homo sapiens |
|
|
|
LLL-12 |
MTT |
Influence on cell viability in STAT3 transfected cells |
1.00 µM |
U87 |
Homo sapiens |
|
|
|
LLL-12 |
MTT |
Influence on cell viability in STAT3 transfected cells |
2.50 µM |
U87 |
Homo sapiens |
|
|
|
LLL-12 |
MTT |
Influence on cell viability in STAT3 transfected cells |
5.00 µM |
U87 |
Homo sapiens |
|
|
|
LLL-12 |
Tumor volume |
Influence on tumor growth |
5.00 mg/kg |
MDA-MB-231 (xenograft) |
Mus musculus |
|
|
|
LLL-12 |
Tumor volume |
Influence on tumor growth |
2.50 mg/kg |
U87 |
Mus musculus |
|
|
|
LLL-12 |
Tumor volume |
Influence on tumor growth |
5.00 mg/kg |
U87 |
Mus musculus |
|
|
|
LLL-12 |
Western Blot |
Influence on protein activity in tumor tissue |
5.00 mg/kg |
MDA-MB-231 (xenograft) |
Mus musculus |
|
p-STAT3 (Y705) |
|
LLL-12 |
Western Blot |
Influence on protein activity in tumor tissue |
5.00 mg/kg |
MDA-MB-231 (xenograft) |
Mus musculus |
|
STAT3 |
|
LLL-12 |
Western Blot |
Influence on protein activity in tumor tissue |
5.00 mg/kg |
MDA-MB-231 (xenograft) |
Mus musculus |
|
|
|
LLL-12 |
Western Blot |
Influence on protein activity in tumor tissue |
5.00 mg/kg |
MDA-MB-231 (xenograft) |
Mus musculus |
|
|
|
LLL-12 |
Western Blot |
Influence on protein activity in tumor tissue |
5.00 µM |
Panc-1 |
Homo sapiens |
|
p-STAT3 (Y705) |
|
LLL-12 |
Western Blot |
Influence on protein activity in tumor tissue |
5.00 µM |
Panc-1 |
Homo sapiens |
|
STAT3 |
|
LLL-12 |
Western Blot |
Influence on protein activity in tumor tissue |
5.00 µM |
Panc-1 |
Homo sapiens |
|
|
|
LLL-12 |
Western Blot |
Influence on protein activity in tumor tissue |
5.00 µM |
Panc-1 |
Homo sapiens |
|
|
|
LLL-12 |
Western Blot |
Influence on protein activity in tumor tissue |
5.00 µM |
Panc-1 |
Homo sapiens |
|
|
|
LLL-12 |
Western Blot |
Influence on protein activity in tumor tissue |
5.00 µM |
Panc-1 |
Homo sapiens |
|
|
|
LLL-12 |
Western Blot |
Influence on protein activity in tumor tissue |
5.00 µM |
Panc-1 |
Homo sapiens |
|
|
|
LLL-12 |
Western Blot |
Influence on protein activity in tumor tissue |
5.00 µM |
Panc-1 |
Homo sapiens |
|
|
|
LLL-12 |
Western Blot |
Influence on protein activity in tumor tissue |
10.00 µM |
U373 |
Homo sapiens |
|
p-STAT3 (Y705) |
|
LLL-12 |
Western Blot |
Influence on protein activity in tumor tissue |
10.00 µM |
U373 |
Homo sapiens |
|
STAT3 |
|
LLL-12 |
Western Blot |
Influence on protein activity in tumor tissue |
10.00 µM |
U373 |
Homo sapiens |
|
|
|
LLL-12 |
Western Blot |
Influence on protein activity in tumor tissue |
10.00 µM |
U373 |
Homo sapiens |
|
|
|
LLL-12 |
Western Blot |
Influence on protein activity in tumor tissue |
10.00 µM |
U373 |
Homo sapiens |
|
|
|
LLL-12 |
Western Blot |
Influence on protein activity in tumor tissue |
10.00 µM |
U373 |
Homo sapiens |
|
|
|
LLL-12 |
Western Blot |
Influence on protein activity in tumor tissue |
10.00 µM |
U373 |
Homo sapiens |
|
|
|
LLL-12 |
Western Blot |
Influence on protein activity in tumor tissue |
10.00 µM |
U373 |
Homo sapiens |
|
|
|
LLL-12 |
Western Blot |
Influence on protein activity in tumor tissue |
10.00 µM |
U373 |
Homo sapiens |
|
|
|
LLL-12 |
Western Blot |
Influence on protein activity in tumor tissue |
10.00 µM |
U373 |
Homo sapiens |
|
|
|
LLL-12 |
MTT |
Influence on cell viability |
0.50 µM |
SNU387 |
Homo sapiens |
|
|
|
LLL-12 |
MTT |
Influence on cell viability |
1.00 µM |
SNU387 |
Homo sapiens |
|
|
|
LLL-12 |
MTT |
Influence on cell viability |
2.50 µM |
SNU387 |
Homo sapiens |
|
|
|
LLL-12 |
MTT |
Influence on cell viability |
5.00 µM |
SNU387 |
Homo sapiens |
|
|
|
LLL-12 |
MTT |
Influence on cell viability |
10.00 µM |
SNU387 |
Homo sapiens |
|
|
|
LLL-12 |
MTT |
Influence on cell viability |
0.50 µM |
SNU398 |
Homo sapiens |
|
|
|
LLL-12 |
MTT |
Influence on cell viability |
1.00 µM |
SNU398 |
Homo sapiens |
|
|
|
LLL-12 |
MTT |
Influence on cell viability |
2.50 µM |
SNU398 |
Homo sapiens |
|
|
|
LLL-12 |
MTT |
Influence on cell viability |
5.00 µM |
SNU398 |
Homo sapiens |
|
|
|
LLL-12 |
MTT |
Influence on cell viability |
10.00 µM |
SNU398 |
Homo sapiens |
|
|
|
LLL-12 |
MTT |
Influence on cell viability |
0.50 µM |
SNU449 |
Homo sapiens |
|
|
|
LLL-12 |
MTT |
Influence on cell viability |
1.00 µM |
SNU449 |
Homo sapiens |
|
|
|
LLL-12 |
MTT |
Influence on cell viability |
2.50 µM |
SNU449 |
Homo sapiens |
|
|
|
LLL-12 |
MTT |
Influence on cell viability |
5.00 µM |
SNU449 |
Homo sapiens |
|
|
|
LLL-12 |
MTT |
Influence on cell viability |
10.00 µM |
SNU449 |
Homo sapiens |
|
|
|
LLL-12 |
MTT |
Influence on cell viability |
0.50 µM |
Hep3B |
Homo sapiens |
|
|
|
LLL-12 |
MTT |
Influence on cell viability |
1.00 µM |
Hep3B |
Homo sapiens |
|
|
|
LLL-12 |
MTT |
Influence on cell viability |
2.50 µM |
Hep3B |
Homo sapiens |
|
|
|
LLL-12 |
MTT |
Influence on cell viability |
5.00 µM |
Hep3B |
Homo sapiens |
|
|
|
LLL-12 |
MTT |
Influence on cell viability |
10.00 µM |
Hep3B |
Homo sapiens |
|
|
|
LLL-12 |
Light microscopy |
Influence on cell viability |
5.00 µM |
SNU387 |
Homo sapiens |
|
|
|
LLL-12 |
Light microscopy |
Influence on cell viability |
10.00 µM |
SNU387 |
Homo sapiens |
|
|
|
LLL-12 |
Light microscopy |
Influence on cell viability |
5.00 µM |
SNU398 |
Homo sapiens |
|
|
|
LLL-12 |
Light microscopy |
Influence on cell viability |
10.00 µM |
SNU398 |
Homo sapiens |
|
|
|
LLL-12 |
Light microscopy |
Influence on cell viability |
5.00 µM |
SNU449 |
Homo sapiens |
|
|
|
LLL-12 |
Light microscopy |
Influence on cell viability |
10.00 µM |
SNU449 |
Homo sapiens |
|
|
|
LLL-12 |
Light microscopy |
Influence on cell viability |
5.00 µM |
Hep3B |
Homo sapiens |
|
|
|
LLL-12 |
Light microscopy |
Influence on cell viability |
10.00 µM |
Hep3B |
Homo sapiens |
|
|
|
LLL-12 |
RT-PCR |
Influence on gene expression |
5.00 µM |
SNU387 |
Homo sapiens |
|
|
|
LLL-12 |
RT-PCR |
Influence on gene expression |
10.00 µM |
SNU387 |
Homo sapiens |
|
|
|
LLL-12 |
RT-PCR |
Influence on gene expression |
5.00 µM |
SNU398 |
Homo sapiens |
|
|
|
LLL-12 |
RT-PCR |
Influence on gene expression |
10.00 µM |
SNU398 |
Homo sapiens |
|
|
|
LLL-12 |
RT-PCR |
Influence on gene expression |
5.00 µM |
SNU449 |
Homo sapiens |
|
|
|
LLL-12 |
RT-PCR |
Influence on gene expression |
10.00 µM |
SNU449 |
Homo sapiens |
|
|
|
LLL-12 |
RT-PCR |
Influence on gene expression |
5.00 µM |
Hep3B |
Homo sapiens |
|
|
|
LLL-12 |
RT-PCR |
Influence on gene expression |
10.00 µM |
Hep3B |
Homo sapiens |
|
|
|
LLL-12 |
RT-PCR |
Influence on gene expression |
5.00 µM |
SNU387 |
Homo sapiens |
|
|
|
LLL-12 |
RT-PCR |
Influence on gene expression |
10.00 µM |
SNU387 |
Homo sapiens |
|
|
|
LLL-12 |
RT-PCR |
Influence on gene expression |
5.00 µM |
SNU398 |
Homo sapiens |
|
|
|
LLL-12 |
RT-PCR |
Influence on gene expression |
10.00 µM |
SNU398 |
Homo sapiens |
|
|
|
LLL-12 |
RT-PCR |
Influence on gene expression |
5.00 µM |
SNU449 |
Homo sapiens |
|
|
|
LLL-12 |
RT-PCR |
Influence on gene expression |
10.00 µM |
SNU449 |
Homo sapiens |
|
|
|
LLL-12 |
RT-PCR |
Influence on gene expression |
5.00 µM |
Hep3B |
Homo sapiens |
|
|
|
LLL-12 |
RT-PCR |
Influence on gene expression |
10.00 µM |
Hep3B |
Homo sapiens |
|
|
|
LLL-12 |
RT-PCR |
Influence on gene expression |
5.00 µM |
SNU387 |
Homo sapiens |
|
|
|
LLL-12 |
RT-PCR |
Influence on gene expression |
10.00 µM |
SNU387 |
Homo sapiens |
|
|
|
LLL-12 |
RT-PCR |
Influence on gene expression |
5.00 µM |
SNU398 |
Homo sapiens |
|
|
|
LLL-12 |
RT-PCR |
Influence on gene expression |
10.00 µM |
SNU398 |
Homo sapiens |
|
|
|
LLL-12 |
RT-PCR |
Influence on gene expression |
5.00 µM |
SNU449 |
Homo sapiens |
|
|
|
LLL-12 |
RT-PCR |
Influence on gene expression |
10.00 µM |
SNU449 |
Homo sapiens |
|
|
|
LLL-12 |
RT-PCR |
Influence on gene expression |
5.00 µM |
Hep3B |
Homo sapiens |
|
|
|
LLL-12 |
RT-PCR |
Influence on gene expression |
10.00 µM |
Hep3B |
Homo sapiens |
|
|
|
LLL-12 |
RT-PCR |
Influence on gene expression |
5.00 µM |
SNU387 |
Homo sapiens |
|
|
|
LLL-12 |
RT-PCR |
Influence on gene expression |
10.00 µM |
SNU387 |
Homo sapiens |
|
|
|
LLL-12 |
RT-PCR |
Influence on gene expression |
5.00 µM |
SNU398 |
Homo sapiens |
|
|
|
LLL-12 |
RT-PCR |
Influence on gene expression |
10.00 µM |
SNU398 |
Homo sapiens |
|
|
|
LLL-12 |
RT-PCR |
Influence on gene expression |
5.00 µM |
SNU449 |
Homo sapiens |
|
|
|
LLL-12 |
RT-PCR |
Influence on gene expression |
10.00 µM |
SNU449 |
Homo sapiens |
|
|
|
LLL-12 |
RT-PCR |
Influence on gene expression |
5.00 µM |
Hep3B |
Homo sapiens |
|
|
|
LLL-12 |
RT-PCR |
Influence on gene expression |
10.00 µM |
Hep3B |
Homo sapiens |
|
|
|
LLL-12 |
RT-PCR |
Influence on gene expression |
5.00 µM |
SNU387 |
Homo sapiens |
|
|
|
LLL-12 |
RT-PCR |
Influence on gene expression |
10.00 µM |
SNU387 |
Homo sapiens |
|
|
|
LLL-12 |
RT-PCR |
Influence on gene expression |
5.00 µM |
SNU398 |
Homo sapiens |
|
|
|
LLL-12 |
RT-PCR |
Influence on gene expression |
10.00 µM |
SNU398 |
Homo sapiens |
|
|
|
LLL-12 |
RT-PCR |
Influence on gene expression |
5.00 µM |
SNU449 |
Homo sapiens |
|
|
|
LLL-12 |
RT-PCR |
Influence on gene expression |
10.00 µM |
SNU449 |
Homo sapiens |
|
|
|
LLL-12 |
RT-PCR |
Influence on gene expression |
5.00 µM |
Hep3B |
Homo sapiens |
|
|
|
LLL-12 |
RT-PCR |
Influence on gene expression |
10.00 µM |
Hep3B |
Homo sapiens |
|
|
|
LLL-12 |
RT-PCR |
Influence on gene expression |
5.00 µM |
SNU387 |
Homo sapiens |
|
|
|
LLL-12 |
RT-PCR |
Influence on gene expression |
10.00 µM |
SNU387 |
Homo sapiens |
|
|
|
LLL-12 |
RT-PCR |
Influence on gene expression |
5.00 µM |
SNU398 |
Homo sapiens |
|
|
|
LLL-12 |
RT-PCR |
Influence on gene expression |
10.00 µM |
SNU398 |
Homo sapiens |
|
|
|
LLL-12 |
RT-PCR |
Influence on gene expression |
5.00 µM |
SNU449 |
Homo sapiens |
|
|
|
LLL-12 |
RT-PCR |
Influence on gene expression |
10.00 µM |
SNU449 |
Homo sapiens |
|
|
|
LLL-12 |
RT-PCR |
Influence on gene expression |
5.00 µM |
Hep3B |
Homo sapiens |
|
|
|
LLL-12 |
RT-PCR |
Influence on gene expression |
10.00 µM |
Hep3B |
Homo sapiens |
|
|
|
LLL-12 |
RT-PCR |
Influence on gene expression |
5.00 µM |
SNU387 |
Homo sapiens |
|
|
|
LLL-12 |
RT-PCR |
Influence on gene expression |
10.00 µM |
SNU387 |
Homo sapiens |
|
|
|
LLL-12 |
RT-PCR |
Influence on gene expression |
5.00 µM |
SNU398 |
Homo sapiens |
|
|
|
LLL-12 |
RT-PCR |
Influence on gene expression |
10.00 µM |
SNU398 |
Homo sapiens |
|
|
|
LLL-12 |
RT-PCR |
Influence on gene expression |
5.00 µM |
SNU449 |
Homo sapiens |
|
|
|
LLL-12 |
RT-PCR |
Influence on gene expression |
10.00 µM |
SNU449 |
Homo sapiens |
|
|
|
LLL-12 |
RT-PCR |
Influence on gene expression |
5.00 µM |
Hep3B |
Homo sapiens |
|
|
|
LLL-12 |
RT-PCR |
Influence on gene expression |
10.00 µM |
Hep3B |
Homo sapiens |
|
|
|
LLL-12 |
Western Blot |
Influence on protein activity |
5.00 µM |
SNU387 |
Homo sapiens |
|
p-STAT3 (Y705) |
|
LLL-12 |
Western Blot |
Influence on protein activity |
10.00 µM |
SNU387 |
Homo sapiens |
|
p-STAT3 (Y705) |
|
LLL-12 |
Western Blot |
Influence on protein activity |
5.00 µM |
SNU398 |
Homo sapiens |
|
p-STAT3 (Y705) |
|
LLL-12 |
Western Blot |
Influence on protein activity |
10.00 µM |
SNU398 |
Homo sapiens |
|
p-STAT3 (Y705) |
|
LLL-12 |
Western Blot |
Influence on protein activity |
5.00 µM |
SNU449 |
Homo sapiens |
|
p-STAT3 (Y705) |
|
LLL-12 |
Western Blot |
Influence on protein activity |
10.00 µM |
SNU449 |
Homo sapiens |
|
p-STAT3 (Y705) |
|
LLL-12 |
Western Blot |
Influence on protein activity |
5.00 µM |
Hep3B |
Homo sapiens |
|
p-STAT3 (Y705) |
|
LLL-12 |
Western Blot |
Influence on protein activity |
10.00 µM |
Hep3B |
Homo sapiens |
|
p-STAT3 (Y705) |
|
LLL-12 |
Western Blot |
Influence on protein activity |
5.00 µM |
SNU387 |
Homo sapiens |
|
STAT3 |
|
LLL-12 |
Western Blot |
Influence on protein activity |
10.00 µM |
SNU387 |
Homo sapiens |
|
STAT3 |
|
LLL-12 |
Western Blot |
Influence on protein activity |
5.00 µM |
SNU398 |
Homo sapiens |
|
STAT3 |
|
LLL-12 |
Western Blot |
Influence on protein activity |
10.00 µM |
SNU398 |
Homo sapiens |
|
STAT3 |
|
LLL-12 |
Western Blot |
Influence on protein activity |
5.00 µM |
SNU449 |
Homo sapiens |
|
STAT3 |
|
LLL-12 |
Western Blot |
Influence on protein activity |
10.00 µM |
SNU449 |
Homo sapiens |
|
STAT3 |
|
LLL-12 |
Western Blot |
Influence on protein activity |
5.00 µM |
Hep3B |
Homo sapiens |
|
STAT3 |
|
LLL-12 |
Western Blot |
Influence on protein activity |
10.00 µM |
Hep3B |
Homo sapiens |
|
STAT3 |
|
LLL-12 |
Western Blot |
Influence on protein activity |
5.00 µM |
SNU387 |
Homo sapiens |
|
|
|
LLL-12 |
Western Blot |
Influence on protein activity |
10.00 µM |
SNU387 |
Homo sapiens |
|
|
|
LLL-12 |
Western Blot |
Influence on protein activity |
5.00 µM |
SNU398 |
Homo sapiens |
|
|
|
LLL-12 |
Western Blot |
Influence on protein activity |
10.00 µM |
SNU398 |
Homo sapiens |
|
|
|
LLL-12 |
Western Blot |
Influence on protein activity |
5.00 µM |
SNU449 |
Homo sapiens |
|
|
|
LLL-12 |
Western Blot |
Influence on protein activity |
10.00 µM |
SNU449 |
Homo sapiens |
|
|
|
LLL-12 |
Western Blot |
Influence on protein activity |
5.00 µM |
Hep3B |
Homo sapiens |
|
|
|
LLL-12 |
Western Blot |
Influence on protein activity |
10.00 µM |
Hep3B |
Homo sapiens |
|
|
|
LLL-12 |
Western Blot |
Influence on protein activity |
5.00 µM |
SNU387 |
Homo sapiens |
|
|
|
LLL-12 |
Western Blot |
Influence on protein activity |
10.00 µM |
SNU387 |
Homo sapiens |
|
|
|
LLL-12 |
Western Blot |
Influence on protein activity |
5.00 µM |
SNU398 |
Homo sapiens |
|
|
|
LLL-12 |
Western Blot |
Influence on protein activity |
10.00 µM |
SNU398 |
Homo sapiens |
|
|
|
LLL-12 |
Western Blot |
Influence on protein activity |
5.00 µM |
SNU449 |
Homo sapiens |
|
|
|
LLL-12 |
Western Blot |
Influence on protein activity |
10.00 µM |
SNU449 |
Homo sapiens |
|
|
|
LLL-12 |
Western Blot |
Influence on protein activity |
5.00 µM |
Hep3B |
Homo sapiens |
|
|
|
LLL-12 |
Western Blot |
Influence on protein activity |
10.00 µM |
Hep3B |
Homo sapiens |
|
|
|
LLL-12 |
Western Blot |
Influence on protein activity |
5.00 µM |
SNU387 |
Homo sapiens |
|
|
|
LLL-12 |
Western Blot |
Influence on protein activity |
10.00 µM |
SNU387 |
Homo sapiens |
|
|
|
LLL-12 |
Western Blot |
Influence on protein activity |
5.00 µM |
SNU398 |
Homo sapiens |
|
|
|
LLL-12 |
Western Blot |
Influence on protein activity |
10.00 µM |
SNU398 |
Homo sapiens |
|
|
|
LLL-12 |
Western Blot |
Influence on protein activity |
5.00 µM |
SNU449 |
Homo sapiens |
|
|
|
LLL-12 |
Western Blot |
Influence on protein activity |
10.00 µM |
SNU449 |
Homo sapiens |
|
|
|
LLL-12 |
Western Blot |
Influence on protein activity |
5.00 µM |
Hep3B |
Homo sapiens |
|
|
|
LLL-12 |
Western Blot |
Influence on protein activity |
10.00 µM |
Hep3B |
Homo sapiens |
|
|
|
LLL-12 |
Western Blot |
Influence on protein activity |
5.00 µM |
SNU387 |
Homo sapiens |
|
|
|
LLL-12 |
Western Blot |
Influence on protein activity |
10.00 µM |
SNU387 |
Homo sapiens |
|
|
|
LLL-12 |
Western Blot |
Influence on protein activity |
5.00 µM |
SNU398 |
Homo sapiens |
|
|
|
LLL-12 |
Western Blot |
Influence on protein activity |
10.00 µM |
SNU398 |
Homo sapiens |
|
|
|
LLL-12 |
Western Blot |
Influence on protein activity |
5.00 µM |
SNU449 |
Homo sapiens |
|
|
|
LLL-12 |
Western Blot |
Influence on protein activity |
10.00 µM |
SNU449 |
Homo sapiens |
|
|
|
LLL-12 |
Western Blot |
Influence on protein activity |
5.00 µM |
Hep3B |
Homo sapiens |
|
|
|
LLL-12 |
Western Blot |
Influence on protein activity |
10.00 µM |
Hep3B |
Homo sapiens |
|
|
|
LLL-12 |
Western Blot |
Influence on protein activity |
5.00 µM |
SNU387 |
Homo sapiens |
|
|
|
LLL-12 |
Western Blot |
Influence on protein activity |
10.00 µM |
SNU387 |
Homo sapiens |
|
|
|
LLL-12 |
Western Blot |
Influence on protein activity |
5.00 µM |
SNU398 |
Homo sapiens |
|
|
|
LLL-12 |
Western Blot |
Influence on protein activity |
10.00 µM |
SNU398 |
Homo sapiens |
|
|
|
LLL-12 |
Western Blot |
Influence on protein activity |
5.00 µM |
SNU449 |
Homo sapiens |
|
|
|
LLL-12 |
Western Blot |
Influence on protein activity |
10.00 µM |
SNU449 |
Homo sapiens |
|
|
|
LLL-12 |
Western Blot |
Influence on protein activity |
5.00 µM |
Hep3B |
Homo sapiens |
|
|
|
LLL-12 |
Western Blot |
Influence on protein activity |
10.00 µM |
Hep3B |
Homo sapiens |
|
|
|
LLL-12 |
Flow cytometry |
Influence on cell cycle |
5.00 µM |
SNU387 |
Homo sapiens |
|
|
|
LLL-12 |
Flow cytometry |
Influence on cell cycle |
5.00 µM |
SNU398 |
Homo sapiens |
|
|
|
LLL-12 |
Flow cytometry |
Influence on cell cycle |
5.00 µM |
SNU449 |
Homo sapiens |
|
|
|
LLL-12 |
Flow cytometry |
Influence on cell cycle |
5.00 µM |
Hep3B |
Homo sapiens |
|
|
|
LLL-12 |
Immunofluorescence staining |
Influence on protein activity |
5.00 µM |
SNU387 |
Homo sapiens |
|
p-STAT3 |
|
LLL-12 |
Immunofluorescence staining |
Influence on protein activity |
5.00 µM |
SNU398 |
Homo sapiens |
|
p-STAT3 |
|
LLL-12 |
Tumor volume |
Influence on tumor growth |
5.00 mg/kg |
SNU398 (xenograft) |
Mus musculus |
nude mice |
|
|
LLL-12 |
Body weight |
Influence on tumor growth |
5.00 mg/kg |
SNU398 (xenograft) |
Mus musculus |
nude mice |
|
|
LLL-12 |
Western Blot |
Influence on protein activity |
5.00 µM |
U2OS |
Homo sapiens |
|
p-STAT3 (Y705) |
|
LLL-12 |
Western Blot |
Influence on protein activity |
5.00 µM |
U2OS |
Homo sapiens |
|
STAT3 |
|
LLL-12 |
Western Blot |
Influence on protein activity |
5.00 µM |
U2OS |
Homo sapiens |
|
|
|
LLL-12 |
Western Blot |
Influence on protein activity |
5.00 µM |
U2OS |
Homo sapiens |
|
|
|
LLL-12 |
Western Blot |
Influence on protein activity |
5.00 µM |
U2OS |
Homo sapiens |
|
|
|
LLL-12 |
Western Blot |
Influence on protein activity |
5.00 µM |
U2OS |
Homo sapiens |
|
|
|
LLL-12 |
Western Blot |
Influence on protein activity |
5.00 µM |
SAOS2 |
Homo sapiens |
|
p-STAT3 (Y705) |
|
LLL-12 |
Western Blot |
Influence on protein activity |
5.00 µM |
SAOS2 |
Homo sapiens |
|
STAT3 |
|
LLL-12 |
Western Blot |
Influence on protein activity |
5.00 µM |
SAOS2 |
Homo sapiens |
|
|
|
LLL-12 |
Western Blot |
Influence on protein activity |
5.00 µM |
SAOS2 |
Homo sapiens |
|
|
|
LLL-12 |
Western Blot |
Influence on protein activity |
5.00 µM |
SAOS2 |
Homo sapiens |
|
|
|
LLL-12 |
Western Blot |
Influence on protein activity |
10.00 µM |
SAOS2 |
Homo sapiens |
|
p-STAT3 (Y705) |
|
LLL-12 |
Western Blot |
Influence on protein activity |
10.00 µM |
SAOS2 |
Homo sapiens |
|
STAT3 |
|
LLL-12 |
Western Blot |
Influence on protein activity |
10.00 µM |
SAOS2 |
Homo sapiens |
|
|
|
LLL-12 |
Western Blot |
Influence on protein activity |
10.00 µM |
SAOS2 |
Homo sapiens |
|
|
|
LLL-12 |
Western Blot |
Influence on protein activity |
10.00 µM |
SAOS2 |
Homo sapiens |
|
|
|
LLL-12 |
Western Blot |
Influence on protein activity |
5.00 µM |
SJSA |
Homo sapiens |
|
p-STAT3 (Y705) |
|
LLL-12 |
Western Blot |
Influence on protein activity |
5.00 µM |
SJSA |
Homo sapiens |
|
STAT3 |
|
LLL-12 |
Western Blot |
Influence on protein activity |
5.00 µM |
SJSA |
Homo sapiens |
|
|
|
LLL-12 |
Western Blot |
Influence on protein activity |
5.00 µM |
SJSA |
Homo sapiens |
|
|
|
LLL-12 |
Western Blot |
Influence on protein activity |
10.00 µM |
SJSA |
Homo sapiens |
|
p-STAT3 (Y705) |
|
LLL-12 |
Western Blot |
Influence on protein activity |
10.00 µM |
SJSA |
Homo sapiens |
|
STAT3 |
|
LLL-12 |
Western Blot |
Influence on protein activity |
10.00 µM |
SJSA |
Homo sapiens |
|
|
|
LLL-12 |
Western Blot |
Influence on protein activity |
10.00 µM |
SJSA |
Homo sapiens |
|
|
|
LLL-12 |
Western Blot |
Influence on protein activity |
5.00 µM |
HSMM |
Homo sapiens |
|
p-STAT3 (Y705) |
|
LLL-12 |
Western Blot |
Influence on protein activity |
5.00 µM |
HSMM |
Homo sapiens |
|
STAT3 |
|
LLL-12 |
Western Blot |
Influence on protein activity |
5.00 µM |
HSMM |
Homo sapiens |
|
|
|
LLL-12 |
Western Blot |
Influence on protein activity |
5.00 µM |
HSMM |
Homo sapiens |
|
|
|
LLL-12 |
Western Blot |
Influence on protein activity |
10.00 µM |
HSMM |
Homo sapiens |
|
p-STAT3 (Y705) |
|
LLL-12 |
Western Blot |
Influence on protein activity |
10.00 µM |
HSMM |
Homo sapiens |
|
STAT3 |
|
LLL-12 |
Western Blot |
Influence on protein activity |
10.00 µM |
HSMM |
Homo sapiens |
|
|
|
LLL-12 |
Western Blot |
Influence on protein activity |
10.00 µM |
HSMM |
Homo sapiens |
|
|
|
LLL-12 |
Flow cytometry |
Influence on cell apoptosis |
10.00 µM |
SAOS2 |
Homo sapiens |
|
|
|
LLL-12 |
Flow cytometry |
Influence on cell apoptosis |
10.00 µM |
SJSA |
Homo sapiens |
|
|
|
LLL-12 |
RT-PCR |
Influence on gene expression |
10.00 µM |
SAOS2 |
Homo sapiens |
|
|
|
LLL-12 |
RT-PCR |
Influence on gene expression |
10.00 µM |
SAOS2 |
Homo sapiens |
|
|
|
LLL-12 |
RT-PCR |
Influence on gene expression |
10.00 µM |
SJSA |
Homo sapiens |
|
|
|
LLL-12 |
RT-PCR |
Influence on gene expression |
10.00 µM |
SAOS2 |
Homo sapiens |
|
|
|
LLL-12 |
RT-PCR |
Influence on gene expression |
10.00 µM |
SJSA |
Homo sapiens |
|
|
|
LLL-12 |
RT-PCR |
Influence on gene expression |
10.00 µM |
SAOS2 |
Homo sapiens |
|
|
|
LLL-12 |
RT-PCR |
Influence on gene expression |
10.00 µM |
SJSA |
Homo sapiens |
|
|
|
LLL-12 |
RT-PCR |
Influence on gene expression |
10.00 µM |
SAOS2 |
Homo sapiens |
|
|
|
LLL-12 |
RT-PCR |
Influence on gene expression |
10.00 µM |
SJSA |
Homo sapiens |
|
|
|
LLL-12 |
Western Blot |
Influence on protein activity in presence of IL-6 |
5.00 µM |
SJSA |
Homo sapiens |
|
p-STAT3 (Y705) |
|
LLL-12 |
Western Blot |
Influence on protein activity in presence of IL-6 |
10.00 µM |
SJSA |
Homo sapiens |
|
p-STAT3 (Y705) |
|
LLL-12 |
Western Blot |
Influence on protein activity in presence of IL-6 |
5.00 µM |
SJSA |
Homo sapiens |
|
STAT3 |
|
LLL-12 |
Western Blot |
Influence on protein activity in presence of IL-6 |
10.00 µM |
SJSA |
Homo sapiens |
|
STAT3 |
|
LLL-12 |
Western Blot |
Influence on protein activity in presence of IL-6 |
5.00 µM |
SJSA |
Homo sapiens |
|
|
|
LLL-12 |
Western Blot |
Influence on protein activity in presence of IL-6 |
10.00 µM |
SJSA |
Homo sapiens |
|
|
|
LLL-12 |
Western Blot |
Influence on protein activity in presence of IFNγ |
5.00 µM |
SJSA |
Homo sapiens |
|
p-STAT1 (Y701) |
|
LLL-12 |
Western Blot |
Influence on protein activity in presence of IFNγ |
10.00 µM |
SJSA |
Homo sapiens |
|
p-STAT1 (Y701) |
|
LLL-12 |
Western Blot |
Influence on protein activity in presence of IFNγ |
5.00 µM |
SJSA |
Homo sapiens |
|
STAT1 |
|
LLL-12 |
Western Blot |
Influence on protein activity in presence of IFNγ |
10.00 µM |
SJSA |
Homo sapiens |
|
STAT1 |
|
LLL-12 |
Western Blot |
Influence on protein activity in presence of IFNγ |
5.00 µM |
SJSA |
Homo sapiens |
|
|
|
LLL-12 |
Western Blot |
Influence on protein activity in presence of IFNγ |
10.00 µM |
SJSA |
Homo sapiens |
|
|
|
LLL-12 |
Focus formation |
Influence on cell proliferation |
2.50 µM |
U2OS |
Homo sapiens |
|
|
|
LLL-12 |
Focus formation |
Influence on cell proliferation |
5.00 µM |
U2OS |
Homo sapiens |
|
|
|
LLL-12 |
Focus formation |
Influence on cell proliferation |
10.00 µM |
U2OS |
Homo sapiens |
|
|
|
LLL-12 |
Focus formation |
Influence on cell proliferation |
2.50 µM |
SAOS2 |
Homo sapiens |
|
|
|
LLL-12 |
Focus formation |
Influence on cell proliferation |
5.00 µM |
SAOS2 |
Homo sapiens |
|
|
|
LLL-12 |
Focus formation |
Influence on cell proliferation |
10.00 µM |
SAOS2 |
Homo sapiens |
|
|
|
LLL-12 |
Focus formation |
Influence on cell proliferation |
2.50 µM |
SJSA |
Homo sapiens |
|
|
|
LLL-12 |
Focus formation |
Influence on cell proliferation |
5.00 µM |
SJSA |
Homo sapiens |
|
|
|
LLL-12 |
Focus formation |
Influence on cell proliferation |
10.00 µM |
SJSA |
Homo sapiens |
|
|
|
LLL-12 |
Wound healing assay |
Influence on cell migration |
2.50 µM |
U2OS |
Homo sapiens |
|
|
|
LLL-12 |
Wound healing assay |
Influence on cell migration |
5.00 µM |
U2OS |
Homo sapiens |
|
|
|
LLL-12 |
Wound healing assay |
Influence on cell migration |
10.00 µM |
U2OS |
Homo sapiens |
|
|
|
LLL-12 |
Wound healing assay |
Influence on cell migration |
2.50 µM |
SAOS2 |
Homo sapiens |
|
|
|
LLL-12 |
Wound healing assay |
Influence on cell migration |
5.00 µM |
SAOS2 |
Homo sapiens |
|
|
|
LLL-12 |
Wound healing assay |
Influence on cell migration |
10.00 µM |
SAOS2 |
Homo sapiens |
|
|
|
LLL-12 |
Wound healing assay |
Influence on cell migration |
2.50 µM |
SJSA |
Homo sapiens |
|
|
|
LLL-12 |
Wound healing assay |
Influence on cell migration |
5.00 µM |
SJSA |
Homo sapiens |
|
|
|
LLL-12 |
Wound healing assay |
Influence on cell migration |
10.00 µM |
SJSA |
Homo sapiens |
|
|
|
LLL-12 |
Tumor volume |
Influence on tumor growth |
5.00 mg/kg |
OS-33 (xenograft) |
Mus musculus |
|
|
|
LLL-12 |
Tumor volume |
Influence on tumor growth |
5.00 mg/kg |
SJSA (xenograft) |
Mus musculus |
|
|
|
LLL-12 |
Western Blot |
Influence on protein activity in tumor tissue |
5.00 mg/kg |
SJSA (xenograft) |
Mus musculus |
|
p-STAT3 (Y705) |
|
LLL-12 |
Western Blot |
Influence on protein activity in tumor tissue |
5.00 mg/kg |
SJSA (xenograft) |
Mus musculus |
|
STAT3 |
|
LLL-12 |
Western Blot |
Influence on protein activity in tumor tissue |
5.00 mg/kg |
SJSA (xenograft) |
Mus musculus |
|
|
|