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Experiments

Compound Investigated event Experiment type Concentration Cell line Organism Animal model Stat protein Details
LLL-12 Influence on protein activity Western Blot 5.00 µM SJSA Homo sapiens p-STAT3 (Y705)
LLL-12 Influence on protein activity Western Blot 5.00 µM SJSA Homo sapiens STAT3
LLL-12 Influence on protein activity Western Blot 5.00 µM SJSA Homo sapiens
LLL-12 Influence on protein activity Western Blot 5.00 µM SJSA Homo sapiens
LLL-12 Influence on protein activity Western Blot 10.00 µM SJSA Homo sapiens p-STAT3 (Y705)
LLL-12 Influence on protein activity Western Blot 10.00 µM SJSA Homo sapiens STAT3
LLL-12 Influence on protein activity Western Blot 10.00 µM SJSA Homo sapiens
LLL-12 Influence on protein activity Western Blot 10.00 µM SJSA Homo sapiens
LLL-12 Influence on cell apoptosis Flow cytometry 10.00 µM SJSA Homo sapiens
LLL-12 Influence on gene expression RT-PCR 10.00 µM SJSA Homo sapiens
LLL-12 Influence on gene expression RT-PCR 10.00 µM SJSA Homo sapiens
LLL-12 Influence on gene expression RT-PCR 10.00 µM SJSA Homo sapiens
LLL-12 Influence on gene expression RT-PCR 10.00 µM SJSA Homo sapiens
LLL-12 Influence on protein activity in presence of IL-6 Western Blot 5.00 µM SJSA Homo sapiens p-STAT3 (Y705)
LLL-12 Influence on protein activity in presence of IL-6 Western Blot 10.00 µM SJSA Homo sapiens p-STAT3 (Y705)
LLL-12 Influence on protein activity in presence of IL-6 Western Blot 5.00 µM SJSA Homo sapiens STAT3
LLL-12 Influence on protein activity in presence of IL-6 Western Blot 10.00 µM SJSA Homo sapiens STAT3
LLL-12 Influence on protein activity in presence of IL-6 Western Blot 5.00 µM SJSA Homo sapiens
LLL-12 Influence on protein activity in presence of IL-6 Western Blot 10.00 µM SJSA Homo sapiens
LLL-12 Influence on protein activity in presence of IFNγ Western Blot 5.00 µM SJSA Homo sapiens p-STAT1 (Y701)
LLL-12 Influence on protein activity in presence of IFNγ Western Blot 10.00 µM SJSA Homo sapiens p-STAT1 (Y701)
LLL-12 Influence on protein activity in presence of IFNγ Western Blot 5.00 µM SJSA Homo sapiens STAT1
LLL-12 Influence on protein activity in presence of IFNγ Western Blot 10.00 µM SJSA Homo sapiens STAT1
LLL-12 Influence on protein activity in presence of IFNγ Western Blot 5.00 µM SJSA Homo sapiens
LLL-12 Influence on protein activity in presence of IFNγ Western Blot 10.00 µM SJSA Homo sapiens
LLL-12 Influence on cell proliferation Focus formation 2.50 µM SJSA Homo sapiens
LLL-12 Influence on cell proliferation Focus formation 5.00 µM SJSA Homo sapiens
LLL-12 Influence on cell proliferation Focus formation 10.00 µM SJSA Homo sapiens
LLL-12 Influence on cell migration Wound healing assay 2.50 µM SJSA Homo sapiens
LLL-12 Influence on cell migration Wound healing assay 5.00 µM SJSA Homo sapiens
LLL-12 Influence on cell migration Wound healing assay 10.00 µM SJSA Homo sapiens
LLL-12 Influence on tumor growth Tumor volume 5.00 mg/kg SJSA (xenograft) Mus musculus
LLL-12 Influence on protein activity in tumor tissue Western Blot 5.00 mg/kg SJSA (xenograft) Mus musculus p-STAT3 (Y705)
LLL-12 Influence on protein activity in tumor tissue Western Blot 5.00 mg/kg SJSA (xenograft) Mus musculus STAT3
LLL-12 Influence on protein activity in tumor tissue Western Blot 5.00 mg/kg SJSA (xenograft) Mus musculus