| LLL-12 |
Influence on protein activity |
Immunofluorescence staining |
5.00 µM |
SNU387 |
Homo sapiens |
|
p-STAT3 |
|
| LLL-12 |
Influence on protein activity |
Immunofluorescence staining |
5.00 µM |
SNU398 |
Homo sapiens |
|
p-STAT3 |
|
| LLL-12 |
Influence on protein activity |
Western Blot |
5.00 µM |
MDA-MB-231 |
Homo sapiens |
|
STAT3 |
|
| LLL-12 |
Influence on protein activity |
Western Blot |
5.00 µM |
SK-BR-3 |
Homo sapiens |
|
STAT3 |
|
| LLL-12 |
Influence on protein activity |
Western Blot |
5.00 µM |
HPAC |
Homo sapiens |
|
STAT3 |
|
| LLL-12 |
Influence on protein activity |
Western Blot |
10.00 µM |
U87 |
Homo sapiens |
|
STAT3 |
|
| LLL-12 |
Influence on protein activity in presence of IL-6 |
Western Blot |
0.50 µM |
MDA-MB-453 |
Homo sapiens |
|
STAT3 |
|
| LLL-12 |
Influence on protein activity in presence of IL-6 |
Western Blot |
1.00 µM |
MDA-MB-453 |
Homo sapiens |
|
STAT3 |
|
| LLL-12 |
Influence on protein activity in presence of IL-6 |
Western Blot |
2.00 µM |
MDA-MB-453 |
Homo sapiens |
|
STAT3 |
|
| LLL-12 |
Influence on protein binding to DNA |
ELISA |
10.00 µM |
SK-BR-3 |
Homo sapiens |
|
STAT3 |
|
| LLL-12 |
Influence on protein binding to DNA |
ELISA |
10.00 µM |
MDA-MB-453 |
Homo sapiens |
|
STAT3 |
|
| LLL-12 |
Influence on protein binding to DNA |
ELISA |
10.00 µM |
HPAC |
Homo sapiens |
|
STAT3 |
|
| LLL-12 |
Influence on protein binding to DNA |
ELISA |
10.00 µM |
U87 |
Homo sapiens |
|
STAT3 |
|
| LLL-12 |
Influence on protein activity |
Luciferase Assay |
1.00 µM |
MDA-MB-231 |
Homo sapiens |
|
STAT3 |
|
| LLL-12 |
Influence on protein activity |
Luciferase Assay |
2.50 µM |
MDA-MB-231 |
Homo sapiens |
|
STAT3 |
|
| LLL-12 |
Influence on protein activity |
Luciferase Assay |
5.00 µM |
MDA-MB-231 |
Homo sapiens |
|
STAT3 |
|
| LLL-12 |
Influence on protein activity |
Luciferase Assay |
10.00 µM |
MDA-MB-231 |
Homo sapiens |
|
STAT3 |
|
| LLL-12 |
Influence on protein activity |
Western Blot |
1.00 µM |
U87 |
Homo sapiens |
|
STAT3 |
|
| LLL-12 |
Influence on protein activity |
Western Blot |
2.50 µM |
U87 |
Homo sapiens |
|
STAT3 |
|
| LLL-12 |
Influence on protein activity |
Western Blot |
5.00 µM |
U87 |
Homo sapiens |
|
STAT3 |
|
| LLL-12 |
Influence on protein activity in STAT3 transfected cells |
Western Blot |
1.00 µM |
U87 |
Homo sapiens |
|
STAT3 |
|
| LLL-12 |
Influence on protein activity in STAT3 transfected cells |
Western Blot |
2.50 µM |
U87 |
Homo sapiens |
|
STAT3 |
|
| LLL-12 |
Influence on protein activity in STAT3 transfected cells |
Western Blot |
5.00 µM |
U87 |
Homo sapiens |
|
STAT3 |
|
| LLL-12 |
Influence on protein activity in tumor tissue |
Western Blot |
5.00 mg/kg |
MDA-MB-231 (xenograft) |
Mus musculus |
|
STAT3 |
|
| LLL-12 |
Influence on protein activity in tumor tissue |
Western Blot |
5.00 µM |
Panc-1 |
Homo sapiens |
|
STAT3 |
|
| LLL-12 |
Influence on protein activity in tumor tissue |
Western Blot |
10.00 µM |
U373 |
Homo sapiens |
|
STAT3 |
|
| LLL-12 |
Influence on protein activity |
Western Blot |
5.00 µM |
SNU387 |
Homo sapiens |
|
STAT3 |
|
| LLL-12 |
Influence on protein activity |
Western Blot |
10.00 µM |
SNU387 |
Homo sapiens |
|
STAT3 |
|
| LLL-12 |
Influence on protein activity |
Western Blot |
5.00 µM |
SNU398 |
Homo sapiens |
|
STAT3 |
|
| LLL-12 |
Influence on protein activity |
Western Blot |
10.00 µM |
SNU398 |
Homo sapiens |
|
STAT3 |
|
| LLL-12 |
Influence on protein activity |
Western Blot |
5.00 µM |
SNU449 |
Homo sapiens |
|
STAT3 |
|
| LLL-12 |
Influence on protein activity |
Western Blot |
10.00 µM |
SNU449 |
Homo sapiens |
|
STAT3 |
|
| LLL-12 |
Influence on protein activity |
Western Blot |
5.00 µM |
Hep3B |
Homo sapiens |
|
STAT3 |
|
| LLL-12 |
Influence on protein activity |
Western Blot |
10.00 µM |
Hep3B |
Homo sapiens |
|
STAT3 |
|
| LLL-12 |
Influence on protein activity |
Western Blot |
5.00 µM |
U2OS |
Homo sapiens |
|
STAT3 |
|
| LLL-12 |
Influence on protein activity |
Western Blot |
5.00 µM |
SAOS2 |
Homo sapiens |
|
STAT3 |
|
| LLL-12 |
Influence on protein activity |
Western Blot |
10.00 µM |
SAOS2 |
Homo sapiens |
|
STAT3 |
|
| LLL-12 |
Influence on protein activity |
Western Blot |
5.00 µM |
SJSA |
Homo sapiens |
|
STAT3 |
|
| LLL-12 |
Influence on protein activity |
Western Blot |
10.00 µM |
SJSA |
Homo sapiens |
|
STAT3 |
|
| LLL-12 |
Influence on protein activity |
Western Blot |
5.00 µM |
HSMM |
Homo sapiens |
|
STAT3 |
|
| LLL-12 |
Influence on protein activity |
Western Blot |
10.00 µM |
HSMM |
Homo sapiens |
|
STAT3 |
|
| LLL-12 |
Influence on protein activity in presence of IL-6 |
Western Blot |
5.00 µM |
SJSA |
Homo sapiens |
|
STAT3 |
|
| LLL-12 |
Influence on protein activity in presence of IL-6 |
Western Blot |
10.00 µM |
SJSA |
Homo sapiens |
|
STAT3 |
|
| LLL-12 |
Influence on protein activity in tumor tissue |
Western Blot |
5.00 mg/kg |
SJSA (xenograft) |
Mus musculus |
|
STAT3 |
|
| LLL-12 |
Influence on protein activity |
Western Blot |
5.00 µM |
MDA-MB-231 |
Homo sapiens |
|
p-STAT3 (Y705) |
|
| LLL-12 |
Influence on protein activity |
Western Blot |
5.00 µM |
SK-BR-3 |
Homo sapiens |
|
p-STAT3 (Y705) |
|
| LLL-12 |
Influence on protein activity |
Western Blot |
5.00 µM |
HPAC |
Homo sapiens |
|
p-STAT3 (Y705) |
|
| LLL-12 |
Influence on protein activity |
Western Blot |
10.00 µM |
U87 |
Homo sapiens |
|
p-STAT3 (Y705) |
|
| LLL-12 |
Influence on protein activity in presence of IL-6 |
Western Blot |
0.50 µM |
MDA-MB-453 |
Homo sapiens |
|
p-STAT3 (Y705) |
|
| LLL-12 |
Influence on protein activity in presence of IL-6 |
Western Blot |
1.00 µM |
MDA-MB-453 |
Homo sapiens |
|
p-STAT3 (Y705) |
|
