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Experiments

Compound Investigated event Experiment type Concentration Cell line Organism Animal model Stat protein Details
LLL-12 Influence on protein activity Immunofluorescence staining 5.00 µM SNU387 Homo sapiens p-STAT3
LLL-12 Influence on protein activity Immunofluorescence staining 5.00 µM SNU398 Homo sapiens p-STAT3
LLL-12 Influence on protein activity Western Blot 5.00 µM MDA-MB-231 Homo sapiens p-STAT3 (Y705)
LLL-12 Influence on protein activity Western Blot 5.00 µM SK-BR-3 Homo sapiens p-STAT3 (Y705)
LLL-12 Influence on protein activity Western Blot 5.00 µM HPAC Homo sapiens p-STAT3 (Y705)
LLL-12 Influence on protein activity Western Blot 10.00 µM U87 Homo sapiens p-STAT3 (Y705)
LLL-12 Influence on protein activity in presence of IL-6 Western Blot 0.50 µM MDA-MB-453 Homo sapiens p-STAT3 (Y705)
LLL-12 Influence on protein activity in presence of IL-6 Western Blot 1.00 µM MDA-MB-453 Homo sapiens p-STAT3 (Y705)
LLL-12 Influence on protein activity in presence of IL-6 Western Blot 2.00 µM MDA-MB-453 Homo sapiens p-STAT3 (Y705)
LLL-12 Influence on protein activity Western Blot 1.00 µM U87 Homo sapiens p-STAT3 (Y705)
LLL-12 Influence on protein activity Western Blot 2.50 µM U87 Homo sapiens p-STAT3 (Y705)
LLL-12 Influence on protein activity Western Blot 5.00 µM U87 Homo sapiens p-STAT3 (Y705)
LLL-12 Influence on protein activity in STAT3 transfected cells Western Blot 1.00 µM U87 Homo sapiens p-STAT3 (Y705)
LLL-12 Influence on protein activity in STAT3 transfected cells Western Blot 2.50 µM U87 Homo sapiens p-STAT3 (Y705)
LLL-12 Influence on protein activity in STAT3 transfected cells Western Blot 5.00 µM U87 Homo sapiens p-STAT3 (Y705)
LLL-12 Influence on protein activity in tumor tissue Western Blot 5.00 mg/kg MDA-MB-231 (xenograft) Mus musculus p-STAT3 (Y705)
LLL-12 Influence on protein activity in tumor tissue Western Blot 5.00 µM Panc-1 Homo sapiens p-STAT3 (Y705)
LLL-12 Influence on protein activity in tumor tissue Western Blot 10.00 µM U373 Homo sapiens p-STAT3 (Y705)
LLL-12 Influence on protein activity Western Blot 5.00 µM SNU387 Homo sapiens p-STAT3 (Y705)
LLL-12 Influence on protein activity Western Blot 10.00 µM SNU387 Homo sapiens p-STAT3 (Y705)
LLL-12 Influence on protein activity Western Blot 5.00 µM SNU398 Homo sapiens p-STAT3 (Y705)
LLL-12 Influence on protein activity Western Blot 10.00 µM SNU398 Homo sapiens p-STAT3 (Y705)
LLL-12 Influence on protein activity Western Blot 5.00 µM SNU449 Homo sapiens p-STAT3 (Y705)
LLL-12 Influence on protein activity Western Blot 10.00 µM SNU449 Homo sapiens p-STAT3 (Y705)
LLL-12 Influence on protein activity Western Blot 5.00 µM Hep3B Homo sapiens p-STAT3 (Y705)
LLL-12 Influence on protein activity Western Blot 10.00 µM Hep3B Homo sapiens p-STAT3 (Y705)
LLL-12 Influence on protein activity Western Blot 5.00 µM U2OS Homo sapiens p-STAT3 (Y705)
LLL-12 Influence on protein activity Western Blot 5.00 µM SAOS2 Homo sapiens p-STAT3 (Y705)
LLL-12 Influence on protein activity Western Blot 10.00 µM SAOS2 Homo sapiens p-STAT3 (Y705)
LLL-12 Influence on protein activity Western Blot 5.00 µM SJSA Homo sapiens p-STAT3 (Y705)
LLL-12 Influence on protein activity Western Blot 10.00 µM SJSA Homo sapiens p-STAT3 (Y705)
LLL-12 Influence on protein activity Western Blot 5.00 µM HSMM Homo sapiens p-STAT3 (Y705)
LLL-12 Influence on protein activity Western Blot 10.00 µM HSMM Homo sapiens p-STAT3 (Y705)
LLL-12 Influence on protein activity in presence of IL-6 Western Blot 5.00 µM SJSA Homo sapiens p-STAT3 (Y705)
LLL-12 Influence on protein activity in presence of IL-6 Western Blot 10.00 µM SJSA Homo sapiens p-STAT3 (Y705)
LLL-12 Influence on protein activity in tumor tissue Western Blot 5.00 mg/kg SJSA (xenograft) Mus musculus p-STAT3 (Y705)