Atiprimod |
MTT Assay |
|
10.00 µM |
Huh-7 |
Homo sapiens |
|
|
|
Atiprimod |
MTT Assay |
|
5.00 µM |
Huh-7 |
Homo sapiens |
|
|
|
Atiprimod |
MTT Assay |
|
2.50 µM |
Huh-7 |
Homo sapiens |
|
|
|
Atiprimod |
MTT Assay |
|
1.25 µM |
Huh-7 |
Homo sapiens |
|
|
|
Atiprimod |
MTT Assay |
|
0.62 µM |
Huh-7 |
Homo sapiens |
|
|
|
Atiprimod |
MTT Assay |
|
0.32 µM |
Huh-7 |
Homo sapiens |
|
|
|
Atiprimod |
MTT Assay |
|
10.00 µM |
HepG2 |
Homo sapiens |
|
|
|
Atiprimod |
MTT Assay |
|
5.00 µM |
HepG2 |
Homo sapiens |
|
|
|
Atiprimod |
MTT Assay |
|
2.50 µM |
HepG2 |
Homo sapiens |
|
|
|
Atiprimod |
MTT Assay |
|
1.25 µM |
HepG2 |
Homo sapiens |
|
|
|
Atiprimod |
MTT Assay |
|
0.62 µM |
HepG2 |
Homo sapiens |
|
|
|
Atiprimod |
MTT Assay |
|
0.32 µM |
HepG2 |
Homo sapiens |
|
|
|
Atiprimod |
MTT Assay |
|
10.00 µM |
HepG2.2.15 |
Homo sapiens |
|
|
|
Atiprimod |
MTT Assay |
|
5.00 µM |
HepG2.2.15 |
Homo sapiens |
|
|
|
Atiprimod |
MTT Assay |
|
2.50 µM |
HepG2.2.15 |
Homo sapiens |
|
|
|
Atiprimod |
MTT Assay |
|
1.25 µM |
HepG2.2.15 |
Homo sapiens |
|
|
|
Atiprimod |
MTT Assay |
|
0.62 µM |
HepG2.2.15 |
Homo sapiens |
|
|
|
Atiprimod |
MTT Assay |
|
0.32 µM |
HepG2.2.15 |
Homo sapiens |
|
|
|
Atiprimod |
Colony Formation |
|
5.00 µM |
HepG2 |
Homo sapiens |
|
|
|
Atiprimod |
Colony Formation |
|
2.50 µM |
HepG2 |
Homo sapiens |
|
|
|
Atiprimod |
Colony Formation |
|
5.00 µM |
HepG2.2.15 |
Homo sapiens |
|
|
|
Atiprimod |
Colony Formation |
|
2.50 µM |
HepG2.2.15 |
Homo sapiens |
|
|
|
Atiprimod |
MTT Assay |
|
10.00 µM |
AD38 |
Homo sapiens |
|
|
|
Atiprimod |
MTT Assay |
|
5.00 µM |
AD38 |
Homo sapiens |
|
|
|
Atiprimod |
MTT Assay |
|
2.50 µM |
AD38 |
Homo sapiens |
|
|
|
Atiprimod |
MTT Assay |
|
1.25 µM |
AD38 |
Homo sapiens |
|
|
|
Atiprimod |
MTT Assay |
|
0.62 µM |
AD38 |
Homo sapiens |
|
|
|
Atiprimod |
MTT Assay |
|
0.32 µM |
AD38 |
Homo sapiens |
|
|
|
Atiprimod |
MTT Assay |
|
10.00 µM |
G64 |
Homo sapiens |
|
|
|
Atiprimod |
MTT Assay |
|
5.00 µM |
G64 |
Homo sapiens |
|
|
|
Atiprimod |
MTT Assay |
|
2.50 µM |
G64 |
Homo sapiens |
|
|
|
Atiprimod |
MTT Assay |
|
1.25 µM |
G64 |
Homo sapiens |
|
|
|
Atiprimod |
MTT Assay |
|
0.62 µM |
G64 |
Homo sapiens |
|
|
|
Atiprimod |
MTT Assay |
|
0.32 µM |
G64 |
Homo sapiens |
|
|
|
Atiprimod |
MTT Assay |
|
10.00 µM |
T cells |
Homo sapiens |
|
|
|
Atiprimod |
MTT Assay |
|
5.00 µM |
T cells |
Homo sapiens |
|
|
|
Atiprimod |
MTT Assay |
|
2.50 µM |
T cells |
Homo sapiens |
|
|
|
Atiprimod |
MTT Assay |
|
1.25 µM |
T cells |
Homo sapiens |
|
|
|
Atiprimod |
MTT Assay |
|
0.62 µM |
T cells |
Homo sapiens |
|
|
|
Atiprimod |
MTT Assay |
|
0.32 µM |
T cells |
Homo sapiens |
|
|
|
Atiprimod |
DNA Fragmentation Assay |
|
10.00 µM |
HepG2 |
Homo sapiens |
|
|
|
Atiprimod |
DNA Fragmentation Assay |
|
5.00 µM |
HepG2 |
Homo sapiens |
|
|
|
Atiprimod |
DNA Fragmentation Assay |
|
2.50 µM |
HepG2 |
Homo sapiens |
|
|
|
Atiprimod |
DNA Fragmentation Assay |
|
1.25 µM |
HepG2 |
Homo sapiens |
|
|
|
Atiprimod |
DNA Fragmentation Assay |
|
10.00 µM |
HepG2.2.15 |
Homo sapiens |
|
|
|
Atiprimod |
DNA Fragmentation Assay |
|
5.00 µM |
HepG2.2.15 |
Homo sapiens |
|
|
|
Atiprimod |
DNA Fragmentation Assay |
|
2.50 µM |
HepG2.2.15 |
Homo sapiens |
|
|
|
Atiprimod |
DNA Fragmentation Assay |
|
1.25 µM |
HepG2.2.15 |
Homo sapiens |
|
|
|
Atiprimod |
Western Blot |
|
5.00 µM |
HepG2 |
Homo sapiens |
|
|
|
Atiprimod |
Western Blot |
|
2.50 µM |
HepG2 |
Homo sapiens |
|
|
|
Atiprimod |
Western Blot |
|
1.25 µM |
HepG2 |
Homo sapiens |
|
|
|
Atiprimod |
Western Blot |
|
0.62 µM |
HepG2 |
Homo sapiens |
|
|
|
Atiprimod |
Western Blot |
|
5.00 µM |
HepG2.2.15 |
Homo sapiens |
|
STAT3 |
|
Atiprimod |
Western Blot |
|
2.50 µM |
HepG2.2.15 |
Homo sapiens |
|
STAT3 |
|
Atiprimod |
Western Blot |
|
1.25 µM |
HepG2.2.15 |
Homo sapiens |
|
STAT3 |
|
Atiprimod |
Western Blot |
|
0.62 µM |
HepG2.2.15 |
Homo sapiens |
|
STAT3 |
|
Atiprimod |
Western Blot |
|
5.00 µM |
AD38 |
Homo sapiens |
|
STAT3 |
|
Atiprimod |
Western Blot |
|
2.50 µM |
AD38 |
Homo sapiens |
|
STAT3 |
|
Atiprimod |
Western Blot |
|
1.25 µM |
AD38 |
Homo sapiens |
|
STAT3 |
|
Atiprimod |
Western Blot |
|
0.62 µM |
AD38 |
Homo sapiens |
|
STAT3 |
|
Atiprimod |
MTT Assay |
Influence on cell proliferation |
0.20 µM |
FDCP-EpoR JAK2WT |
Mus musculus |
|
|
|
Atiprimod |
MTT Assay |
Influence on cell proliferation |
0.40 µM |
FDCP-EpoR JAK2WT |
Mus musculus |
|
|
|
Atiprimod |
MTT Assay |
Influence on cell proliferation |
0.60 µM |
FDCP-EpoR JAK2WT |
Mus musculus |
|
|
|
Atiprimod |
MTT Assay |
Influence on cell proliferation |
0.80 µM |
FDCP-EpoR JAK2WT |
Mus musculus |
|
|
|
Atiprimod |
MTT Assay |
Influence on cell proliferation |
0.20 µM |
FDCP-EpoR JAK2V617F |
Mus musculus |
|
|
|
Atiprimod |
MTT Assay |
Influence on cell proliferation |
0.40 µM |
FDCP-EpoR JAK2V617F |
Mus musculus |
|
|
|
Atiprimod |
MTT Assay |
Influence on cell proliferation |
0.60 µM |
FDCP-EpoR JAK2V617F |
Mus musculus |
|
|
|
Atiprimod |
MTT Assay |
Influence on cell proliferation |
0.80 µM |
FDCP-EpoR JAK2V617F |
Mus musculus |
|
|
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
FDCP-EpoR JAK2WT |
Mus musculus |
|
|
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
FDCP-EpoR JAK2WT |
Mus musculus |
|
|
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
FDCP-EpoR JAK2WT |
Mus musculus |
|
|
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
FDCP-EpoR JAK2V617F |
Mus musculus |
|
|
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
FDCP-EpoR JAK2V617F |
Mus musculus |
|
|
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
FDCP-EpoR JAK2V617F |
Mus musculus |
|
|
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
FDCP-EpoR JAK2WT |
Mus musculus |
|
|
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
FDCP-EpoR JAK2WT |
Mus musculus |
|
|
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
FDCP-EpoR JAK2WT |
Mus musculus |
|
|
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
FDCP-EpoR JAK2V617F |
Mus musculus |
|
|
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
FDCP-EpoR JAK2V617F |
Mus musculus |
|
|
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
FDCP-EpoR JAK2V617F |
Mus musculus |
|
|
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
SET-2 |
Homo sapiens |
|
|
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
SET-2 |
Homo sapiens |
|
|
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
SET-2 |
Homo sapiens |
|
|
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
SET-2 |
Homo sapiens |
|
|
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
SET-2 |
Homo sapiens |
|
|
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
SET-2 |
Homo sapiens |
|
|
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
SET-2 |
Homo sapiens |
|
|
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
SET-2 |
Homo sapiens |
|
|
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
SET-2 |
Homo sapiens |
|
|
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
SET-2 |
Homo sapiens |
|
|
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
SET-2 |
Homo sapiens |
|
|
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
SET-2 |
Homo sapiens |
|
|
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
CMK |
Homo sapiens |
|
|
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
CMK |
Homo sapiens |
|
|
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
CMK |
Homo sapiens |
|
|
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
CMK |
Homo sapiens |
|
|
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
CMK |
Homo sapiens |
|
|
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
CMK |
Homo sapiens |
|
|
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
CMK |
Homo sapiens |
|
|
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
CMK |
Homo sapiens |
|
|
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
CMK |
Homo sapiens |
|
|
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
CMK |
Homo sapiens |
|
|
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
CMK |
Homo sapiens |
|
|
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
CMK |
Homo sapiens |
|
|
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
FDCP-EpoR JAK2WT |
Mus musculus |
|
p-STAT3 |
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
FDCP-EpoR JAK2WT |
Mus musculus |
|
p-STAT3 |
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
FDCP-EpoR JAK2WT |
Mus musculus |
|
p-STAT3 |
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
FDCP-EpoR JAK2V617F |
Mus musculus |
|
p-STAT3 |
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
FDCP-EpoR JAK2V617F |
Mus musculus |
|
p-STAT3 |
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
FDCP-EpoR JAK2V617F |
Mus musculus |
|
p-STAT3 |
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
FDCP-EpoR JAK2WT |
Mus musculus |
|
STAT3 |
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
FDCP-EpoR JAK2WT |
Mus musculus |
|
STAT3 |
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
FDCP-EpoR JAK2WT |
Mus musculus |
|
STAT3 |
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
FDCP-EpoR JAK2V617F |
Mus musculus |
|
STAT3 |
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
FDCP-EpoR JAK2V617F |
Mus musculus |
|
STAT3 |
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
FDCP-EpoR JAK2V617F |
Mus musculus |
|
STAT3 |
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
FDCP-EpoR JAK2WT |
Mus musculus |
|
p-STAT5 |
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
FDCP-EpoR JAK2WT |
Mus musculus |
|
p-STAT5 |
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
FDCP-EpoR JAK2WT |
Mus musculus |
|
p-STAT5 |
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
FDCP-EpoR JAK2V617F |
Mus musculus |
|
p-STAT5 |
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
FDCP-EpoR JAK2V617F |
Mus musculus |
|
p-STAT5 |
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
FDCP-EpoR JAK2V617F |
Mus musculus |
|
p-STAT5 |
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
FDCP-EpoR JAK2WT |
Mus musculus |
|
STAT5 |
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
FDCP-EpoR JAK2WT |
Mus musculus |
|
STAT5 |
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
FDCP-EpoR JAK2WT |
Mus musculus |
|
STAT5 |
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
FDCP-EpoR JAK2V617F |
Mus musculus |
|
STAT5 |
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
FDCP-EpoR JAK2V617F |
Mus musculus |
|
STAT5 |
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
FDCP-EpoR JAK2V617F |
Mus musculus |
|
STAT5 |
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
FDCP-EpoR JAK2WT |
Mus musculus |
|
|
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
FDCP-EpoR JAK2WT |
Mus musculus |
|
|
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
FDCP-EpoR JAK2WT |
Mus musculus |
|
|
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
FDCP-EpoR JAK2V617F |
Mus musculus |
|
|
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
FDCP-EpoR JAK2V617F |
Mus musculus |
|
|
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
FDCP-EpoR JAK2V617F |
Mus musculus |
|
|
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
FDCP-EpoR JAK2WT |
Mus musculus |
|
|
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
FDCP-EpoR JAK2WT |
Mus musculus |
|
|
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
FDCP-EpoR JAK2WT |
Mus musculus |
|
|
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
FDCP-EpoR JAK2V617F |
Mus musculus |
|
|
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
FDCP-EpoR JAK2V617F |
Mus musculus |
|
|
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
FDCP-EpoR JAK2V617F |
Mus musculus |
|
|
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
FDCP-EpoR JAK2WT |
Mus musculus |
|
|
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
FDCP-EpoR JAK2WT |
Mus musculus |
|
|
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
FDCP-EpoR JAK2WT |
Mus musculus |
|
|
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
FDCP-EpoR JAK2V617F |
Mus musculus |
|
|
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
FDCP-EpoR JAK2V617F |
Mus musculus |
|
|
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
FDCP-EpoR JAK2V617F |
Mus musculus |
|
|
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
SET-2 JAK2V617F |
Homo sapiens |
|
p-STAT5 |
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
SET-2 JAK2V617F |
Homo sapiens |
|
p-STAT5 |
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
SET-2 JAK2V617F |
Homo sapiens |
|
p-STAT5 |
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
CMK JAK2WT |
Homo sapiens |
|
p-STAT5 |
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
CMK JAK2WT |
Homo sapiens |
|
p-STAT5 |
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
CMK JAK2WT |
Homo sapiens |
|
p-STAT5 |
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
SET-2 JAK2V617F |
Homo sapiens |
|
STAT5 |
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
SET-2 JAK2V617F |
Homo sapiens |
|
STAT5 |
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
SET-2 JAK2V617F |
Homo sapiens |
|
STAT5 |
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
CMK JAK2WT |
Homo sapiens |
|
STAT5 |
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
CMK JAK2WT |
Homo sapiens |
|
STAT5 |
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
CMK JAK2WT |
Homo sapiens |
|
STAT5 |
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
SET-2 JAK2V617F |
Homo sapiens |
|
p-STAT3 |
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
SET-2 JAK2V617F |
Homo sapiens |
|
p-STAT3 |
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
SET-2 JAK2V617F |
Homo sapiens |
|
p-STAT3 |
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
CMK JAK2WT |
Homo sapiens |
|
p-STAT3 |
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
CMK JAK2WT |
Homo sapiens |
|
p-STAT3 |
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
CMK JAK2WT |
Homo sapiens |
|
p-STAT3 |
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
SET-2 JAK2V617F |
Homo sapiens |
|
STAT3 |
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
SET-2 JAK2V617F |
Homo sapiens |
|
STAT3 |
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
SET-2 JAK2V617F |
Homo sapiens |
|
STAT3 |
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
CMK JAK2WT |
Homo sapiens |
|
STAT3 |
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
CMK JAK2WT |
Homo sapiens |
|
STAT3 |
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
CMK JAK2WT |
Homo sapiens |
|
STAT3 |
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
SET-2 JAK2V617F |
Homo sapiens |
|
|
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
SET-2 JAK2V617F |
Homo sapiens |
|
|
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
SET-2 JAK2V617F |
Homo sapiens |
|
|
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
CMK JAK2WT |
Homo sapiens |
|
|
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
CMK JAK2WT |
Homo sapiens |
|
|
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
CMK JAK2WT |
Homo sapiens |
|
|
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
SET-2 JAK2V617F |
Homo sapiens |
|
|
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
SET-2 JAK2V617F |
Homo sapiens |
|
|
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
SET-2 JAK2V617F |
Homo sapiens |
|
|
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
CMK JAK2WT |
Homo sapiens |
|
|
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
CMK JAK2WT |
Homo sapiens |
|
|
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
CMK JAK2WT |
Homo sapiens |
|
|
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
SET-2 JAK2V617F |
Homo sapiens |
|
|
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
SET-2 JAK2V617F |
Homo sapiens |
|
|
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
SET-2 JAK2V617F |
Homo sapiens |
|
|
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
CMK JAK2WT |
Homo sapiens |
|
|
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
CMK JAK2WT |
Homo sapiens |
|
|
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
CMK JAK2WT |
Homo sapiens |
|
|
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
FDCP-EpoR JAK2WT |
Mus musculus |
|
|
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
FDCP-EpoR JAK2WT |
Mus musculus |
|
|
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
FDCP-EpoR JAK2WT |
Mus musculus |
|
|
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
FDCP-EpoR JAK2V617F |
Mus musculus |
|
|
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
FDCP-EpoR JAK2V617F |
Mus musculus |
|
|
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
FDCP-EpoR JAK2V617F |
Mus musculus |
|
|
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
FDCP-EpoR JAK2WT |
Mus musculus |
|
|
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
FDCP-EpoR JAK2WT |
Mus musculus |
|
|
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
FDCP-EpoR JAK2WT |
Mus musculus |
|
|
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
FDCP-EpoR JAK2V617F |
Mus musculus |
|
|
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
FDCP-EpoR JAK2V617F |
Mus musculus |
|
|
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
FDCP-EpoR JAK2V617F |
Mus musculus |
|
|
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
SET-2 |
Homo sapiens |
|
|
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
SET-2 |
Homo sapiens |
|
|
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
SET-2 |
Homo sapiens |
|
|
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
CMK |
Homo sapiens |
|
|
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
CMK |
Homo sapiens |
|
|
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
CMK |
Homo sapiens |
|
|
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
SET-2 |
Homo sapiens |
|
|
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
SET-2 |
Homo sapiens |
|
|
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
SET-2 |
Homo sapiens |
|
|
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
CMK |
Homo sapiens |
|
|
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
CMK |
Homo sapiens |
|
|
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
CMK |
Homo sapiens |
|
|
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
SET-2 |
Homo sapiens |
|
|
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
SET-2 |
Homo sapiens |
|
|
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
SET-2 |
Homo sapiens |
|
|
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
CMK |
Homo sapiens |
|
|
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
CMK |
Homo sapiens |
|
|
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
CMK |
Homo sapiens |
|
|
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
SET-2 |
Homo sapiens |
|
|
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
SET-2 |
Homo sapiens |
|
|
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
SET-2 |
Homo sapiens |
|
|
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
CMK |
Homo sapiens |
|
|
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
CMK |
Homo sapiens |
|
|
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
CMK |
Homo sapiens |
|
|
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
SET-2 |
Homo sapiens |
|
|
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
SET-2 |
Homo sapiens |
|
|
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
SET-2 |
Homo sapiens |
|
|
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
CMK |
Homo sapiens |
|
|
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
CMK |
Homo sapiens |
|
|
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
CMK |
Homo sapiens |
|
|
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
SET-2 |
Homo sapiens |
|
|
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
SET-2 |
Homo sapiens |
|
|
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
SET-2 |
Homo sapiens |
|
|
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
CMK |
Homo sapiens |
|
|
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
CMK |
Homo sapiens |
|
|
|
Atiprimod |
Western Blot |
Influence on protein activity |
N/A µM |
CMK |
Homo sapiens |
|
|
|
Atiprimod |
MTS |
Influence on patient derived cell proliferation |
N/A µM |
expanded erythroid progenitor cells |
Homo sapiens |
patient material |
|
|
Atiprimod |
ELISA |
Influence on cytokine production |
3.00 µM |
MMI |
|
|
|
|
Atiprimod |
ELISA |
Influence on cytokine production |
3.00 µM |
MMIR |
|
|
|
|
Atiprimod |
ELISA |
Influence on cytokine production |
3.00 µM |
U266-BI |
|
|
|
|
Atiprimod |
ELISA |
Influence on cytokine production |
3.00 µM |
OCI-MY5 |
|
|
|
|
Atiprimod |
EMSA |
Influence on protein-DNA interaction |
5.00 µM |
U266-B1 |
Homo sapiens |
|
|
|
Atiprimod |
EMSA |
Influence on protein-DNA interaction |
10.00 µM |
U266-B1 |
Homo sapiens |
|
|
|
Atiprimod |
EMSA |
Influence on protein-DNA interaction |
25.00 µM |
U266-B1 |
Homo sapiens |
|
|
|
Atiprimod |
EMSA |
Influence on protein-DNA interaction |
50.00 µM |
U266-B1 |
Homo sapiens |
|
|
|
Atiprimod |
Western Blot |
Influence on protein activity |
8.00 µM |
U266-B1 |
Homo sapiens |
|
p-STAT3 |
|
Atiprimod |
Western Blot |
Influence on protein activity |
4.00 µM |
U266-B1 |
Homo sapiens |
|
p-STAT3 |
|
Atiprimod |
Western Blot |
Influence on protein activity |
2.00 µM |
U266-B1 |
Homo sapiens |
|
p-STAT3 |
|
Atiprimod |
Western Blot |
Influence on protein activity |
1.00 µM |
U266-B1 |
Homo sapiens |
|
p-STAT3 |
|
Atiprimod |
Western Blot |
Influence on protein activity |
8.00 µM |
U266-B1 |
Homo sapiens |
|
STAT3 |
|
Atiprimod |
Western Blot |
Influence on protein activity |
4.00 µM |
U266-B1 |
Homo sapiens |
|
STAT3 |
|
Atiprimod |
Western Blot |
Influence on protein activity |
2.00 µM |
U266-B1 |
Homo sapiens |
|
STAT3 |
|
Atiprimod |
Western Blot |
Influence on protein activity |
1.00 µM |
U266-B1 |
Homo sapiens |
|
STAT3 |
|
Atiprimod |
Western Blot |
Influence on protein activity |
8.00 µM |
U266-B1 |
Homo sapiens |
|
|
|
Atiprimod |
Western Blot |
Influence on protein activity |
4.00 µM |
U266-B1 |
Homo sapiens |
|
|
|
Atiprimod |
Western Blot |
Influence on protein activity |
2.00 µM |
U266-B1 |
Homo sapiens |
|
|
|
Atiprimod |
Western Blot |
Influence on protein activity |
1.00 µM |
U266-B1 |
Homo sapiens |
|
|
|
Atiprimod |
EMSA |
Influence on protein-DNA interaction |
2.50 µM |
U266-B1 |
Homo sapiens |
|
STAT3 |
|
Atiprimod |
Western Blot |
Influence on protein activity in presence of IL-6 |
2.50 µM |
MM-1 |
Homo sapiens |
|
p-STAT3 |
|
Atiprimod |
Western Blot |
Influence on protein activity in presence of IL-6 |
2.50 µM |
MM-1 |
Homo sapiens |
|
STAT3 |
|
Atiprimod |
Western Blot |
Influence on protein activity in presence of IL-6 |
2.50 µM |
MM-1 |
Homo sapiens |
|
|
|
Atiprimod |
MTT Assay |
Influence on cell viability |
2.00 µM |
MM-1 |
Homo sapiens |
|
|
|
Atiprimod |
MTT Assay |
Influence on cell viability |
4.00 µM |
MM-1 |
Homo sapiens |
|
|
|
Atiprimod |
MTT Assay |
Influence on cell viability |
6.00 µM |
MM-1 |
Homo sapiens |
|
|
|
Atiprimod |
MTT Assay |
Influence on cell viability |
8.00 µM |
MM-1 |
Homo sapiens |
|
|
|
Atiprimod |
MTT Assay |
Influence on cell viability |
2.00 µM |
U266-B1 |
Homo sapiens |
|
|
|
Atiprimod |
MTT Assay |
Influence on cell viability |
4.00 µM |
U266-B1 |
Homo sapiens |
|
|
|
Atiprimod |
MTT Assay |
Influence on cell viability |
6.00 µM |
U266-B1 |
Homo sapiens |
|
|
|
Atiprimod |
MTT Assay |
Influence on cell viability |
8.00 µM |
U266-B1 |
Homo sapiens |
|
|
|
Atiprimod |
MTT Assay |
Influence on cell viability |
2.00 µM |
OCI-MY5 |
Homo sapiens |
|
|
|
Atiprimod |
MTT Assay |
Influence on cell viability |
4.00 µM |
OCI-MY5 |
Homo sapiens |
|
|
|
Atiprimod |
MTT Assay |
Influence on cell viability |
6.00 µM |
OCI-MY5 |
Homo sapiens |
|
|
|
Atiprimod |
MTT Assay |
Influence on cell viability |
8.00 µM |
OCI-MY5 |
Homo sapiens |
|
|
|
Atiprimod |
MTT Assay |
Influence on cell viability |
2.00 µM |
MM-1R |
Homo sapiens |
|
|
|
Atiprimod |
MTT Assay |
Influence on cell viability |
4.00 µM |
MM-1R |
Homo sapiens |
|
|
|
Atiprimod |
MTT Assay |
Influence on cell viability |
6.00 µM |
MM-1R |
Homo sapiens |
|
|
|
Atiprimod |
MTT Assay |
Influence on cell viability |
8.00 µM |
MM-1R |
Homo sapiens |
|
|
|
Atiprimod |
MTT Assay |
Influence on cell viability |
2.00 µM |
RPMI-8266 |
Homo sapiens |
|
|
|
Atiprimod |
MTT Assay |
Influence on cell viability |
4.00 µM |
RPMI-8266 |
Homo sapiens |
|
|
|
Atiprimod |
MTT Assay |
Influence on cell viability |
6.00 µM |
RPMI-8266 |
Homo sapiens |
|
|
|
Atiprimod |
MTT Assay |
Influence on cell viability |
8.00 µM |
RPMI-8266 |
Homo sapiens |
|
|
|
Atiprimod |
ELISA |
Influence on cytokine receptor production |
3.00 µM |
MMI |
|
|
|
|
Atiprimod |
ELISA |
Influence on cytokine receptor production |
3.00 µM |
MMIR |
|
|
|
|
Atiprimod |
ELISA |
Influence on cytokine receptor production |
3.00 µM |
U266-BI |
|
|
|
|
Atiprimod |
ELISA |
Influence on cytokine receptor production |
3.00 µM |
OCI-MY5 |
|
|
|
|
Atiprimod |
Flow cytometry |
Influence on cell cycle |
6.00 µM |
U266-B1 |
Homo sapiens |
|
|
|
Atiprimod |
Western Blot |
Influence on protein activity |
1.00 µM |
U266-B1 |
Homo sapiens |
|
|
|
Atiprimod |
Western Blot |
Influence on protein activity |
2.00 µM |
U266-B1 |
Homo sapiens |
|
|
|
Atiprimod |
Western Blot |
Influence on protein activity |
4.00 µM |
U266-B1 |
Homo sapiens |
|
|
|
Atiprimod |
Western Blot |
Influence on protein activity |
8.00 µM |
U266-B1 |
Homo sapiens |
|
|
|
Atiprimod |
Western Blot |
Influence on protein activity |
1.00 µM |
U266-B1 |
Homo sapiens |
|
|
|
Atiprimod |
Western Blot |
Influence on protein activity |
2.00 µM |
U266-B1 |
Homo sapiens |
|
|
|
Atiprimod |
Western Blot |
Influence on protein activity |
4.00 µM |
U266-B1 |
Homo sapiens |
|
|
|
Atiprimod |
Western Blot |
Influence on protein activity |
8.00 µM |
U266-B1 |
Homo sapiens |
|
|
|
Atiprimod |
Western Blot |
Influence on protein activity |
1.00 µM |
U266-B1 |
Homo sapiens |
|
|
|
Atiprimod |
Western Blot |
Influence on protein activity |
2.00 µM |
U266-B1 |
Homo sapiens |
|
|
|
Atiprimod |
Western Blot |
Influence on protein activity |
4.00 µM |
U266-B1 |
Homo sapiens |
|
|
|
Atiprimod |
Western Blot |
Influence on protein activity |
8.00 µM |
U266-B1 |
Homo sapiens |
|
|
|
Atiprimod |
Flow cytometry |
Influence on cell proliferation |
2.00 µM |
U266-B1 |
Homo sapiens |
|
|
|
Atiprimod |
Flow cytometry |
Influence on cell proliferation |
4.00 µM |
U266-B1 |
Homo sapiens |
|
|
|
Atiprimod |
Flow cytometry |
Influence on cell proliferation |
8.00 µM |
U266-B1 |
Homo sapiens |
|
|
|
Atiprimod |
Western Blot |
Influence on cell apoptosis |
1.00 µM |
U266-B1 |
Homo sapiens |
|
|
|
Atiprimod |
Western Blot |
Influence on cell apoptosis |
2.00 µM |
U266-B1 |
Homo sapiens |
|
|
|
Atiprimod |
Western Blot |
Influence on cell apoptosis |
4.00 µM |
U266-B1 |
Homo sapiens |
|
|
|
Atiprimod |
Western Blot |
Influence on cell apoptosis |
8.00 µM |
U266-B1 |
Homo sapiens |
|
|
|
Atiprimod |
Western Blot |
Influence on cell apoptosis |
1.00 µM |
U266-B1 |
Homo sapiens |
|
|
|
Atiprimod |
Western Blot |
Influence on cell apoptosis |
2.00 µM |
U266-B1 |
Homo sapiens |
|
|
|
Atiprimod |
Western Blot |
Influence on cell apoptosis |
4.00 µM |
U266-B1 |
Homo sapiens |
|
|
|
Atiprimod |
Western Blot |
Influence on cell apoptosis |
8.00 µM |
U266-B1 |
Homo sapiens |
|
|
|
Atiprimod |
Western Blot |
Influence on cell apoptosis |
1.00 µM |
U266-B1 |
Homo sapiens |
|
|
|
Atiprimod |
Western Blot |
Influence on cell apoptosis |
2.00 µM |
U266-B1 |
Homo sapiens |
|
|
|
Atiprimod |
Western Blot |
Influence on cell apoptosis |
4.00 µM |
U266-B1 |
Homo sapiens |
|
|
|
Atiprimod |
Western Blot |
Influence on cell apoptosis |
8.00 µM |
U266-B1 |
Homo sapiens |
|
|
|
Atiprimod |
Western Blot |
Influence on cell apoptosis |
1.00 µM |
U266-B1 |
Homo sapiens |
|
|
|
Atiprimod |
Western Blot |
Influence on cell apoptosis |
2.00 µM |
U266-B1 |
Homo sapiens |
|
|
|
Atiprimod |
Western Blot |
Influence on cell apoptosis |
4.00 µM |
U266-B1 |
Homo sapiens |
|
|
|
Atiprimod |
Western Blot |
Influence on cell apoptosis |
8.00 µM |
U266-B1 |
Homo sapiens |
|
|
|
Atiprimod |
Western Blot |
Influence on cell apoptosis |
1.00 µM |
U266-B1 |
Homo sapiens |
|
|
|
Atiprimod |
Western Blot |
Influence on cell apoptosis |
2.00 µM |
U266-B1 |
Homo sapiens |
|
|
|
Atiprimod |
Western Blot |
Influence on cell apoptosis |
4.00 µM |
U266-B1 |
Homo sapiens |
|
|
|
Atiprimod |
Western Blot |
Influence on cell apoptosis |
8.00 µM |
U266-B1 |
Homo sapiens |
|
|
|
Atiprimod |
Colony Formation |
Influence on cell proliferation |
1.00 µM |
MM |
Homo sapiens (patient) |
|
|
|
Atiprimod |
Colony Formation |
Influence on cell proliferation |
2.00 µM |
MM |
Homo sapiens (patient) |
|
|
|
Atiprimod |
Colony Formation |
Influence on cell proliferation |
4.00 µM |
MM |
Homo sapiens (patient) |
|
|
|
Atiprimod |
Colony Formation |
Influence on cell proliferation |
8.00 µM |
MM |
Homo sapiens (patient) |
|
|
|
Atiprimod |
MTT Assay |
Influence on cell viability |
1.00 µM |
MM |
Homo sapiens (patient) |
|
|
|
Atiprimod |
MTT Assay |
Influence on cell viability |
2.00 µM |
MM |
Homo sapiens (patient) |
|
|
|
Atiprimod |
MTT Assay |
Influence on cell viability |
4.00 µM |
MM |
Homo sapiens (patient) |
|
|
|
Atiprimod |
MTT Assay |
Influence on cell viability |
8.00 µM |
MM |
Homo sapiens (patient) |
|
|
|