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Experiments

Compound Investigated event Experiment type Concentration Cell line Organism Animal model Stat protein Details
Brevilin A Influence on STAT3 nuclear localization Western Blot 3.00 µM A375 Homo sapiens
Brevilin A Influence on STAT3 nuclear localization Western Blot 1.00 µM A2058 Homo sapiens
Brevilin A Influence on STAT3 nuclear localization Western Blot 2.00 µM A2058 Homo sapiens
Brevilin A Influence on STAT3 nuclear localization Western Blot 3.00 µM A2058 Homo sapiens
Brevilin A Influence on protein and mRNA levels on STAT3 target genes Western Blot 1.00 µM A375 Homo sapiens
Brevilin A Influence on protein and mRNA levels on STAT3 target genes Western Blot 2.00 µM A375 Homo sapiens
Brevilin A Influence on protein and mRNA levels on STAT3 target genes Western Blot 3.00 µM A375 Homo sapiens
Brevilin A Influence on protein and mRNA levels on STAT3 target genes Western Blot 1.00 µM A2058 Homo sapiens
Brevilin A Influence on protein and mRNA levels on STAT3 target genes Western Blot 2.00 µM A2058 Homo sapiens
Brevilin A Influence on protein and mRNA levels on STAT3 target genes Western Blot 3.00 µM A2058 Homo sapiens
Brevilin A Influence on protein and mRNA levels on STAT3 target genes Western Blot 1.00 µM A375 Homo sapiens
Brevilin A Influence on protein and mRNA levels on STAT3 target genes Western Blot 2.00 µM A375 Homo sapiens
Brevilin A Influence on protein and mRNA levels on STAT3 target genes Western Blot 3.00 µM A375 Homo sapiens
Brevilin A Influence on protein and mRNA levels on STAT3 target genes Western Blot 1.00 µM A2058 Homo sapiens
Brevilin A Influence on protein and mRNA levels on STAT3 target genes Western Blot 2.00 µM A2058 Homo sapiens
Brevilin A Influence on protein and mRNA levels on STAT3 target genes Western Blot 3.00 µM A2058 Homo sapiens
Brevilin A Influence on protein and mRNA levels on STAT3 target genes Western Blot 1.00 µM A375 Homo sapiens
Brevilin A Influence on protein and mRNA levels on STAT3 target genes Western Blot 2.00 µM A375 Homo sapiens
Brevilin A Influence on protein and mRNA levels on STAT3 target genes Western Blot 3.00 µM A375 Homo sapiens
Brevilin A Influence on protein and mRNA levels on STAT3 target genes Western Blot 1.00 µM A2058 Homo sapiens
Brevilin A Influence on protein and mRNA levels on STAT3 target genes Western Blot 2.00 µM A2058 Homo sapiens
Brevilin A Influence on protein and mRNA levels on STAT3 target genes Western Blot 3.00 µM A2058 Homo sapiens
Brevilin A Influence on protein and mRNA levels on STAT3 target genes Western Blot 0.50 µM A375 Homo sapiens
Brevilin A Influence on protein and mRNA levels on STAT3 target genes Western Blot 1.00 µM A375 Homo sapiens
Brevilin A Influence on protein and mRNA levels on STAT3 target genes Western Blot 2.00 µM A375 Homo sapiens
Brevilin A Influence on protein and mRNA levels on STAT3 target genes Western Blot 0.50 µM A2058 Homo sapiens
Brevilin A Influence on protein and mRNA levels on STAT3 target genes Western Blot 1.00 µM A2058 Homo sapiens
Brevilin A Influence on protein and mRNA levels on STAT3 target genes Western Blot 2.00 µM A2058 Homo sapiens
Brevilin A Influence on protein and mRNA levels on STAT3 target genes Western Blot 0.50 µM A375 Homo sapiens
Brevilin A Influence on protein and mRNA levels on STAT3 target genes Western Blot 0.50 µM A2058 Homo sapiens
Brevilin A Influence on protein and mRNA levels on STAT3 target genes RT-qPCR 0.50 µM A375 Homo sapiens
Brevilin A Influence on protein and mRNA levels on STAT3 target genes RT-qPCR 1.00 µM A375 Homo sapiens
Brevilin A Influence on protein and mRNA levels on STAT3 target genes RT-qPCR 2.00 µM A375 Homo sapiens
Brevilin A Influence on protein and mRNA levels on STAT3 target genes RT-qPCR 0.50 µM A2058 Homo sapiens
Brevilin A Influence on protein and mRNA levels on STAT3 target genes RT-qPCR 1.00 µM A2058 Homo sapiens
Brevilin A Influence on protein and mRNA levels on STAT3 target genes RT-qPCR 2.00 µM A2058 Homo sapiens
Brevilin A Influence on STAT3 overexpression in cell migration and viability assays MTT 1.00 µM A375 Homo sapiens
Brevilin A Influence on STAT3 overexpression in cell migration and viability assays MTT 2.00 µM A375 Homo sapiens
Brevilin A Influence on STAT3 overexpression in cell migration and viability assays MTT 3.00 µM A375 Homo sapiens
Brevilin A Influence on STAT3 overexpression in cell migration and viability assays MTT 1.00 µM A375 (STAT3) Homo sapiens
Brevilin A Influence on STAT3 overexpression in cell migration and viability assays MTT 2.00 µM A375 (STAT3) Homo sapiens
Brevilin A Influence on STAT3 overexpression in cell migration and viability assays MTT 3.00 µM A375 (STAT3) Homo sapiens
C188 Influence on tumor growth Mammosphere forming efficiency (MSFE) 10.00 µM SUM159 Homo sapiens
C188 Influence on tumor growth Mammosphere forming efficiency (MSFE) 10.00 µM BT549 Homo sapiens
C188 Influence on tumor growth Tumor volume 12.50 mg/kg BCM2665(xengraft) Mus musculus SCID Beige mice
C188 Influence on tumor growth MSFE 12.50 mg/kg BCM2665(xengraft) Mus musculus SCID Beige mice
C188 Influence on tumor growth Western Blot 12.50 mg/kg BCM2665(xengraft) Mus musculus SCID Beige mice p-STAT3
C188 Influence on tumor growth Western Blot 12.50 mg/kg BCM2665(xengraft) Mus musculus SCID Beige mice
C188 Influence on tumor growth Immunohistochemistry 12.50 mg/kg BCM2665(xengraft) Mus musculus SCID Beige mice p-STAT3
C188 TIC marker measurement Tumor volume 12.50 mg/kg MC1 Mus musculus SCID Beige mice