Investigated event: Influence on protein activity in presence of IFNγ

Name Value
Compound AG490
Investigated event Influence on protein activity in presence of IFNγ
Experiment type Western Blot
Concentration 3.00 µM
Cell line 1774 macrophages
Organism Homo sapiens
Animal model
STAT protein
Other iNOS
Reference
JAK inhibitors AG-490 and WHI-P154 decrease IFN-gamma-induced iNOS expression and NO production in macrophages. Mediators of inflammation Outi Sareila, Riku Korhonen, Outi Kärpänniemi, Riina Nieminen, Hannu Kankaanranta, Eeva Moilanen, 2006, 2, None, None, 10.1155/MI/2006/16161 DOI: 10.1155/MI/2006/16161 PUBMED: 16883061 PMCID: PMC1592588