Investigated event: Influence on nitric oxide (NO) generation

Name Value
Compound AG490
Investigated event Influence on nitric oxide (NO) generation
Experiment type Griess reaction
Concentration 3.00 µM
Cell line 1774 macrophages
Organism Homo sapiens
Animal model
STAT protein
Other
Reference
JAK inhibitors AG-490 and WHI-P154 decrease IFN-gamma-induced iNOS expression and NO production in macrophages. Mediators of inflammation Outi Sareila, Riku Korhonen, Outi Kärpänniemi, Riina Nieminen, Hannu Kankaanranta, Eeva Moilanen, 2006, 2, None, None, 10.1155/MI/2006/16161 DOI: 10.1155/MI/2006/16161 PUBMED: 16883061 PMCID: PMC1592588