Investigated event: Influence on gene expression levels in presence of IFNγ

Name Value
Compound AG490
Investigated event Influence on gene expression levels in presence of IFNγ
Experiment type RT-qPCR
Concentration 10.00 µM
Cell line 1774 macrophages
Organism Homo sapiens
Animal model
STAT protein
Other iNOS
Reference
JAK inhibitors AG-490 and WHI-P154 decrease IFN-gamma-induced iNOS expression and NO production in macrophages. Mediators of inflammation Outi Sareila, Riku Korhonen, Outi Kärpänniemi, Riina Nieminen, Hannu Kankaanranta, Eeva Moilanen, 2006, 2, None, None, 10.1155/MI/2006/16161 DOI: 10.1155/MI/2006/16161 PUBMED: 16883061 PMCID: PMC1592588