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Experiments

Compound Investigated event Experiment type Concentration Cell line Organism Animal model Stat protein Details
3,3 diindolylmethane Influence on cell motility Western Blot 75.00 µM OVCAR-3 Homo sapiens
3,3 diindolylmethane Influence on cell motility Western Blot 75.00 µM OVCAR-3 Homo sapiens
3,3 diindolylmethane Influence on cell motility in presence of IL-6 Western Blot 75.00 µM SKOV-3 Homo sapiens
3,3 diindolylmethane Influence on cell motility in presence of IL-6 Western Blot 75.00 µM SKOV-3 Homo sapiens
3,3 diindolylmethane Influence on cell motility in presence of IL-6 Western Blot 75.00 µM SKOV-3 Homo sapiens
3,3 diindolylmethane Influence on cell viability in presence of cisplatin SRB cell survival assay 20.00 µM SKOV-3 Homo sapiens
3,3 diindolylmethane Influence on cell viability in presence of cisplatin SRB cell survival assay 50.00 µM SKOV-3 Homo sapiens
3,3 diindolylmethane Influence on protin actiity in presence of cisplatin Western Blot 50.00 µM SKOV-3 Homo sapiens p-STAT3 (Y705)
3,3 diindolylmethane Influence on protin actiity in presence of cisplatin Western Blot 50.00 µM SKOV-3 Homo sapiens STAT3
3,3 diindolylmethane Influence on protin actiity in presence of cisplatin Western Blot 50.00 µM SKOV-3 Homo sapiens
3,3 diindolylmethane Influence on protin actiity in presence of cisplatin Western Blot 50.00 µM SKOV-3 Homo sapiens
3,3 diindolylmethane Influence on protin actiity in presence of cisplatin Western Blot 50.00 µM SKOV-3 Homo sapiens
3,3 diindolylmethane Influence on protin actiity in presence of cisplatin Western Blot 50.00 µM SKOV-3 Homo sapiens
3,3 diindolylmethane Influence on protein translocation in presence of cisplatin Western Blot 50.00 µM SKOV-3 Homo sapiens p-STAT3 (Y705) (nucleus)
3,3 diindolylmethane Influence on protein translocation in presence of cisplatin Western Blot 50.00 µM SKOV-3 Homo sapiens STAT3 (nucleus)
3,3 diindolylmethane Influence on protein translocation in presence of cisplatin Western Blot 50.00 µM SKOV-3 Homo sapiens
3,3 diindolylmethane Influence on protein-DNA interaction in presence of cisplatin Luciferase activity 50.00 µM SKOV-3 Homo sapiens STAT3
3,3 diindolylmethane Influence on cell motility in presence of cisplatin Aortic ring assay 50.00 µM SKOV-3 Homo sapiens
3,3 diindolylmethane Influence on VEGF secretion in presence of cisplatin ELISA 50.00 µM SKOV-3 Homo sapiens
3,3 diindolylmethane Influence on VEGF secretion in presence of cisplatin ELISA 50.00 µM OVCAR-3 Homo sapiens
3,3 diindolylmethane Influence on tumor growth in presence of cisplatin Tumor volume 3.00 mg/kg SKOV-3 (xenograft) Mus musculus athymic nude mice
3,3 diindolylmethane Influence on tumor growth in presence of cisplatin Mice weight 3.00 mg/kg SKOV-3 (xenograft) Mus musculus athymic nude mice
3,3 diindolylmethane Influence on tumor growth Tumor volume 3.00 mg/kg SKOV-3 (xenograft) Mus musculus athymic nude mice
3,3 diindolylmethane Influence on tumor growth Mice weight 3.00 mg/kg SKOV-3 (xenograft) Mus musculus athymic nude mice
3,3 diindolylmethane Influence on protein activity in tumor tissue Western Blot 3.00 mg/kg SKOV-3 (xenograft) Mus musculus athymic nude mice p-STAT3 (Y705)
3,3 diindolylmethane Influence on protein activity in tumor tissue Western Blot 3.00 mg/kg SKOV-3 (xenograft) Mus musculus athymic nude mice STAT3
3,3 diindolylmethane Influence on protein activity in tumor tissue Western Blot 3.00 mg/kg SKOV-3 (xenograft) Mus musculus athymic nude mice
3,3 diindolylmethane Influence on protein activity in tumor tissue Western Blot 3.00 mg/kg SKOV-3 (xenograft) Mus musculus athymic nude mice
3,3 diindolylmethane Influence on protein activity in tumor tissue Western Blot 3.00 mg/kg SKOV-3 (xenograft) Mus musculus athymic nude mice
3,3 diindolylmethane Influence on protein activity in tumor tissue Western Blot 3.00 mg/kg SKOV-3 (xenograft) Mus musculus athymic nude mice
3,3 diindolylmethane Influence on protein activity in tumor tissue Western Blot 3.00 mg/kg SKOV-3 (xenograft) Mus musculus athymic nude mice
3,3 diindolylmethane Influence on protein activity in tumor tissue in presence of cisplatin Western Blot 3.00 mg/kg SKOV-3 (xenograft) Mus musculus athymic nude mice p-STAT3 (Y705)
3,3 diindolylmethane Influence on protein activity in tumor tissue in presence of cisplatin Western Blot 3.00 mg/kg SKOV-3 (xenograft) Mus musculus athymic nude mice STAT3
3,3 diindolylmethane Influence on protein activity in tumor tissue in presence of cisplatin Western Blot 3.00 mg/kg SKOV-3 (xenograft) Mus musculus athymic nude mice
3,3 diindolylmethane Influence on protein activity in tumor tissue in presence of cisplatin Western Blot 3.00 mg/kg SKOV-3 (xenograft) Mus musculus athymic nude mice
3,3 diindolylmethane Influence on protein activity in tumor tissue in presence of cisplatin Western Blot 3.00 mg/kg SKOV-3 (xenograft) Mus musculus athymic nude mice
3,3 diindolylmethane Influence on protein activity in tumor tissue in presence of cisplatin Western Blot 3.00 mg/kg SKOV-3 (xenograft) Mus musculus athymic nude mice
3,3 diindolylmethane Influence on protein activity in tumor tissue in presence of cisplatin Western Blot 3.00 mg/kg SKOV-3 (xenograft) Mus musculus athymic nude mice
3,3 diindolylmethane Influence on cytokine secretion in tumor tissue ELISA 3.00 mg/kg SKOV-3 (xenograft) Mus musculus athymic nude mice
3,3 diindolylmethane Influence on epithelial cell viability SRB cell survival assay 20.00 µM NOSE Homo sapiens
3,3 diindolylmethane Influence on epithelial cell viability SRB cell survival assay 40.00 µM NOSE Homo sapiens
3,3 diindolylmethane Influence on epithelial cell viability SRB cell survival assay 60.00 µM NOSE Homo sapiens
3,3 diindolylmethane Influence on epithelial cell viability SRB cell survival assay 80.00 µM NOSE Homo sapiens
3,3 diindolylmethane Influence on epithelial cell viability SRB cell survival assay 100.00 µM NOSE Homo sapiens
3,3 diindolylmethane Influence on epithelial cell viability SRB cell survival assay 120.00 µM NOSE Homo sapiens
3,3 diindolylmethane Influence on epithelial cell viability SRB cell survival assay 20.00 µM TOV-21G Homo sapiens
3,3 diindolylmethane Influence on epithelial cell viability SRB cell survival assay 40.00 µM TOV-21G Homo sapiens
3,3 diindolylmethane Influence on epithelial cell viability SRB cell survival assay 60.00 µM TOV-21G Homo sapiens
3,3 diindolylmethane Influence on epithelial cell viability SRB cell survival assay 80.00 µM TOV-21G Homo sapiens
3,3 diindolylmethane Influence on epithelial cell viability SRB cell survival assay 100.00 µM TOV-21G Homo sapiens