Investigated event: Influence on protein activity in tumor tissue

Name Value
Compound 3,3 diindolylmethane
Investigated event Influence on protein activity in tumor tissue
Experiment type Western Blot
Concentration 3.00 mg/kg
Cell line SKOV-3 (xenograft)
Organism Mus musculus
Animal model athymic nude mice
STAT protein
Other Cleaved Caspase-3
Reference
Diindolylmethane suppresses ovarian cancer growth and potentiates the effect of cisplatin in tumor mouse model by targeting signal transducer and activator of transcription 3 (STAT3). BMC medicine Prabodh K Kandala, Sanjay K Srivastava, 10, None, 2012-01-26, 2012-01-26, 10.1186/1741-7015-10-9. DOI: 10.1186/1741-7015-10-9. PUBMED: 22280969 PMCID: PMC3298725