Investigated event: Influence on protein activity in tumor tissue

Name Value
Compound 3,3 diindolylmethane
Investigated event Influence on protein activity in tumor tissue
Experiment type Western Blot
Concentration 3.00 mg/kg
Cell line SKOV-3 (xenograft)
Organism Mus musculus
Animal model athymic nude mice
STAT protein
Other Survivin
Reference
Diindolylmethane suppresses ovarian cancer growth and potentiates the effect of cisplatin in tumor mouse model by targeting signal transducer and activator of transcription 3 (STAT3). BMC medicine Prabodh K Kandala, Sanjay K Srivastava, 10, None, 2012-01-26, 2012-01-26, 10.1186/1741-7015-10-9. DOI: 10.1186/1741-7015-10-9. PUBMED: 22280969 PMCID: PMC3298725