| BBMD3 (berbamine derivative) |
Inhibition of Jak/STAT signalling |
Western Blot |
10.00 µM |
A2058 |
Homo sapiens |
|
|
|
| BBMD3 (berbamine derivative) |
Inhibition of Jak/STAT signalling |
Western Blot |
10.00 µM |
A375 |
Homo sapiens |
|
|
|
| BBMD3 (berbamine derivative) |
Inhibition of Jak/STAT signalling |
Western Blot |
10.00 µM |
G361 |
Homo sapiens |
|
|
|
| BBMD3 (berbamine derivative) |
Inhibition of Jak/STAT signalling |
Western Blot |
10.00 µM |
SK-MEL-5 |
Homo sapiens |
|
|
|
| BBMD3 (berbamine derivative) |
Inhibition of Jak/STAT signalling |
Western Blot |
0.50 µM |
A2058 |
Homo sapiens |
|
|
|
| BBMD3 (berbamine derivative) |
Inhibition of Jak/STAT signalling |
Western Blot |
1.00 µM |
A2058 |
Homo sapiens |
|
|
|
| BBMD3 (berbamine derivative) |
Inhibition of Jak/STAT signalling |
Western Blot |
5.00 µM |
A2058 |
Homo sapiens |
|
|
|
| BBMD3 (berbamine derivative) |
Inhibition of Jak/STAT signalling in presence of IL-6 |
Western Blot |
0.50 µM |
A2058 |
Homo sapiens |
|
|
|
| BBMD3 (berbamine derivative) |
Inhibition of Jak/STAT signalling in presence of IL-6 |
Western Blot |
1.00 µM |
A2058 |
Homo sapiens |
|
|
|
| BBMD3 (berbamine derivative) |
Inhibition of Jak/STAT signalling in presence of IL-6 |
Western Blot |
3.00 µM |
A2058 |
Homo sapiens |
|
|
|
| BBMD3 (berbamine derivative) |
Inhibition of Jak/STAT signalling in presence of IL-6 |
Western Blot |
5.00 µM |
A2058 |
Homo sapiens |
|
|
|
| BBMD3 (berbamine derivative) |
Inhibition of Jak/STAT signalling in presence of IL-6 |
Western Blot |
10.00 µM |
A2058 |
Homo sapiens |
|
|
|
| BBMD3 (berbamine derivative) |
Influence on JAK2 phosphorylation |
Autophosphorylation kinase activity |
0.10 µM |
A2058 |
Homo sapiens |
|
|
|
| BBMD3 (berbamine derivative) |
Influence on JAK2 phosphorylation |
Autophosphorylation kinase activity |
0.50 µM |
A2058 |
Homo sapiens |
|
|
|
| BBMD3 (berbamine derivative) |
Influence on JAK2 phosphorylation |
Autophosphorylation kinase activity |
1.00 µM |
A2058 |
Homo sapiens |
|
|
|
| BBMD3 (berbamine derivative) |
Influence on JAK2 phosphorylation |
Autophosphorylation kinase activity |
5.00 µM |
A2058 |
Homo sapiens |
|
|
|
| BBMD3 (berbamine derivative) |
Influence on JAK2 phosphorylation |
Autophosphorylation kinase activity |
10.00 µM |
A2058 |
Homo sapiens |
|
|
|
| Berbamine |
Downregulation of IFNγ |
Western Blot |
50.00 mg/kg |
Splenocytes |
Mus musculus |
c57BL/6 |
|
|
