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Experiments

Compound Investigated event Experiment type Concentration Cell line Organism Animal model Stat protein Details
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 10.00 µM A2058 Homo sapiens
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 10.00 µM A375 Homo sapiens
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 10.00 µM G361 Homo sapiens
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 10.00 µM SK-MEL-5 Homo sapiens
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 10.00 µM A2058 Homo sapiens
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 10.00 µM A375 Homo sapiens
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 10.00 µM G361 Homo sapiens
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 10.00 µM SK-MEL-5 Homo sapiens
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 0.50 µM A2058 Homo sapiens
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 1.00 µM A2058 Homo sapiens
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 5.00 µM A2058 Homo sapiens
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 0.50 µM A2058 Homo sapiens
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 1.00 µM A2058 Homo sapiens
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling Western Blot 5.00 µM A2058 Homo sapiens
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling in presence of IL-6 Western Blot 0.50 µM A2058 Homo sapiens
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling in presence of IL-6 Western Blot 1.00 µM A2058 Homo sapiens
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling in presence of IL-6 Western Blot 3.00 µM A2058 Homo sapiens
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling in presence of IL-6 Western Blot 5.00 µM A2058 Homo sapiens
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling in presence of IL-6 Western Blot 10.00 µM A2058 Homo sapiens
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling in presence of IL-6 Western Blot 0.50 µM A2058 Homo sapiens
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling in presence of IL-6 Western Blot 1.00 µM A2058 Homo sapiens
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling in presence of IL-6 Western Blot 3.00 µM A2058 Homo sapiens
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling in presence of IL-6 Western Blot 5.00 µM A2058 Homo sapiens
BBMD3 (berbamine derivative) Inhibition of Jak/STAT signalling in presence of IL-6 Western Blot 10.00 µM A2058 Homo sapiens
BBMD3 (berbamine derivative) Influence on JAK2 phosphorylation Autophosphorylation kinase activity 0.10 µM A2058 Homo sapiens
BBMD3 (berbamine derivative) Influence on JAK2 phosphorylation Autophosphorylation kinase activity 0.50 µM A2058 Homo sapiens
BBMD3 (berbamine derivative) Influence on JAK2 phosphorylation Autophosphorylation kinase activity 1.00 µM A2058 Homo sapiens
BBMD3 (berbamine derivative) Influence on JAK2 phosphorylation Autophosphorylation kinase activity 5.00 µM A2058 Homo sapiens
BBMD3 (berbamine derivative) Influence on JAK2 phosphorylation Autophosphorylation kinase activity 10.00 µM A2058 Homo sapiens
BBMD3 (berbamine derivative) Influence on JAK2 phosphorylation Autophosphorylation kinase activity 0.10 µM A2058 Homo sapiens
BBMD3 (berbamine derivative) Influence on JAK2 phosphorylation Autophosphorylation kinase activity 0.50 µM A2058 Homo sapiens
BBMD3 (berbamine derivative) Influence on JAK2 phosphorylation Autophosphorylation kinase activity 1.00 µM A2058 Homo sapiens
BBMD3 (berbamine derivative) Influence on JAK2 phosphorylation Autophosphorylation kinase activity 5.00 µM A2058 Homo sapiens
BBMD3 (berbamine derivative) Influence on JAK2 phosphorylation Autophosphorylation kinase activity 10.00 µM A2058 Homo sapiens
Berbamine Downregulation of IFNγ Western Blot 50.00 mg/kg Splenocytes Mus musculus c57BL/6
Berbamine Downregulation of IFNγ Western Blot 50.00 mg/kg Splenocytes Mus musculus c57BL/6