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Experiments

Compound Investigated event Experiment type Concentration Cell line Organism Animal model Stat protein Details
inS3-54 Influence on chromatin in situ- chromatin bound fraction Western Blot 10.00 µM A549 Homo sapiens
inS3-54 Influence on chromatin in situ- chromatin bound fraction Western Blot 20.00 µM A549 Homo sapiens
inS3-54A18 Influence on cell viability Sulforhodamine B assay N/A N/A A549 Homo sapiens
inS3-54A18 Influence on cell motility Wound healing assay 5.00 µM A549 Homo sapiens
inS3-54A18 Influence on cell motility Wound healing assay 10.00 µM A549 Homo sapiens
inS3-54A18 Influence on cell motility Invasion assay 5.00 µM A549 Homo sapiens
inS3-54A18 Influence on cell motility Invasion assay 10.00 µM A549 Homo sapiens
inS3-54A18 Influence on protein activity Chromatin immunoprecipitation assay 5.00 µM A549 Homo sapiens STAT3 (cytosol)
inS3-54A18 Influence on protein activity Chromatin immunoprecipitation assay 10.00 µM A549 Homo sapiens STAT3 (cytosol)
inS3-54A18 Influence on protein activity Chromatin immunoprecipitation assay 5.00 µM A549 Homo sapiens
inS3-54A18 Influence on protein activity Chromatin immunoprecipitation assay 10.00 µM A549 Homo sapiens
inS3-54A18 Influence on protein activity Chromatin immunoprecipitation assay 5.00 µM A549 Homo sapiens
inS3-54A18 Influence on protein activity Chromatin immunoprecipitation assay 10.00 µM A549 Homo sapiens
inS3-54A18 Influence on protein activity Chromatin immunoprecipitation assay 5.00 µM A549 Homo sapiens
inS3-54A18 Influence on protein activity Chromatin immunoprecipitation assay 10.00 µM A549 Homo sapiens
inS3-54A18 Influence on protein activity Chromatin immunoprecipitation assay 5.00 µM A549 Homo sapiens STAT3 (soluble nuclear)
inS3-54A18 Influence on protein activity Chromatin immunoprecipitation assay 10.00 µM A549 Homo sapiens STAT3 (soluble nuclear)
inS3-54A18 Influence on protein activity Chromatin immunoprecipitation assay 5.00 µM A549 Homo sapiens
inS3-54A18 Influence on protein activity Chromatin immunoprecipitation assay 10.00 µM A549 Homo sapiens
inS3-54A18 Influence on protein activity Chromatin immunoprecipitation assay 5.00 µM A549 Homo sapiens
inS3-54A18 Influence on protein activity Chromatin immunoprecipitation assay 10.00 µM A549 Homo sapiens
inS3-54A18 Influence on protein activity Chromatin immunoprecipitation assay 5.00 µM A549 Homo sapiens
inS3-54A18 Influence on protein activity Chromatin immunoprecipitation assay 10.00 µM A549 Homo sapiens
inS3-54A18 Influence on protein activity Chromatin immunoprecipitation assay 5.00 µM A549 Homo sapiens STAT3 (chromatin bound)
inS3-54A18 Influence on protein activity Chromatin immunoprecipitation assay 10.00 µM A549 Homo sapiens STAT3 (chromatin bound)
inS3-54A18 Influence on protein activity Chromatin immunoprecipitation assay 5.00 µM A549 Homo sapiens
inS3-54A18 Influence on protein activity Chromatin immunoprecipitation assay 10.00 µM A549 Homo sapiens
inS3-54A18 Influence on protein activity Chromatin immunoprecipitation assay 5.00 µM A549 Homo sapiens
inS3-54A18 Influence on protein activity Chromatin immunoprecipitation assay 10.00 µM A549 Homo sapiens
inS3-54A18 Influence on protein activity Chromatin immunoprecipitation assay 5.00 µM A549 Homo sapiens
inS3-54A18 Influence on protein activity Chromatin immunoprecipitation assay 10.00 µM A549 Homo sapiens
inS3-54A18 Influence on protein activity in presence of IL-6 Western Blot 10.00 µM A549 Homo sapiens p-STAT3
inS3-54A18 Influence on protein activity in presence of IL-6 Western Blot 10.00 µM A549 Homo sapiens STAT3
inS3-54A18 Influence on protein activity in presence of IL-6 Western Blot 10.00 µM A549 Homo sapiens
inS3-54A18 Influence on protein activity in presence of IL-6 Western Blot 10.00 µM A549 Homo sapiens
inS3-54A18 Influence on tumor growth Tumor volume 200.00 mg/kg A549 (xenograft) Mus musculus NOD/SCID
inS3-54A18 Influence on tumor growth Body weight 200.00 mg/kg A549 (xenograft) Mus musculus NOD/SCID
inS3-54A18 Influence on tumor growth Tumor weight 200.00 mg/kg A549 (xenograft) Mus musculus NOD/SCID
inS3-54A18 Influence on tumor growth Organ weight 200.00 mg/kg A549 (xenograft) Mus musculus NOD/SCID
inS3-54A18 Influence on protein activity Immunohistochemistry 200.00 mg/kg A549 (xenograft) Mus musculus NOD/SCID STAT3
inS3-54A18 Influence on protein activity Immunohistochemistry 200.00 mg/kg A549 (xenograft) Mus musculus NOD/SCID
inS3-54A18 Influence on protein activity Immunohistochemistry 200.00 mg/kg A549 (xenograft) Mus musculus NOD/SCID