Investigated event: Influence on protein activity

Name Value
Compound inS3-54A18
Investigated event Influence on protein activity
Experiment type Chromatin immunoprecipitation assay
Concentration 10.00 µM
Cell line A549
Organism Homo sapiens
Animal model
STAT protein
Other Tubulin (chromatin bound)
Reference
Small-molecule inhibitors targeting the DNA-binding domain of STAT3 suppress tumor growth, metastasis and STAT3 target gene expression in vivo. Oncogene W Huang, Z Dong, Y Chen, F Wang, C J Wang, H Peng, Y He, G Hangoc, K Pollok, G Sandusky, X-Y Fu, H E Broxmeyer, Z-Y Zhang, J-Y Liu, J-T Zhang, 35, 6, 2016-02-11, 2015-06-15, 10.1038/onc.2015.215 DOI: 10.1038/onc.2015.215 PUBMED: 26073084 PMCID: 26073084