Investigated event: Influence on tumor growth

Name Value
Compound inS3-54A18
Investigated event Influence on tumor growth
Experiment type Body weight
Concentration 200.00 mg/kg
Cell line A549 (xenograft)
Organism Mus musculus
Animal model NOD/SCID
STAT protein
Other
Reference
Small-molecule inhibitors targeting the DNA-binding domain of STAT3 suppress tumor growth, metastasis and STAT3 target gene expression in vivo. Oncogene W Huang, Z Dong, Y Chen, F Wang, C J Wang, H Peng, Y He, G Hangoc, K Pollok, G Sandusky, X-Y Fu, H E Broxmeyer, Z-Y Zhang, J-Y Liu, J-T Zhang, 35, 6, 2016-02-11, 2015-06-15, 10.1038/onc.2015.215 DOI: 10.1038/onc.2015.215 PUBMED: 26073084 PMCID: 26073084