| Berbamine |
Downregulation of IFNγ |
Western Blot |
50.00 mg/kg |
Splenocytes |
Mus musculus |
c57BL/6 |
|
|
| Berbamine |
Downregulation of IFNγ |
Western Blot |
50.00 mg/kg |
Splenocytes |
Mus musculus |
c57BL/6 |
|
|
| Berbamine |
Downregulation of IFNγ |
Western Blot |
50.00 mg/kg |
Splenocytes |
Mus musculus |
c57BL/6 |
|
|
| Berbamine |
Downregulation of IFNγ |
Western Blot |
50.00 mg/kg |
Splenocytes |
Mus musculus |
c57BL/6 |
|
|
| Berbamine |
Downregulation of IFNγ |
Western Blot |
50.00 mg/kg |
Splenocytes |
Mus musculus |
c57BL/6 |
|
|
| Berbamine |
Downregulation of IFNγ |
Western Blot |
50.00 mg/kg |
Splenocytes |
Mus musculus |
c57BL/6 |
p-STAT4 |
|
| Berbamine |
Downregulation of IFNγ |
Western Blot |
50.00 mg/kg |
Splenocytes |
Mus musculus |
c57BL/6 |
STAT4 |
|
| Berbamine |
Downregulation of IFNγ |
Immunoprecipitation |
50.00 mg/kg |
Splenocytes |
Mus musculus |
c57BL/6 |
STAT4 |
|
| Berbamine |
Downregulation of IFNγ |
Immunoprecipitation |
50.00 mg/kg |
Splenocytes |
Mus musculus |
c57BL/6 |
|
|
| BBMD3 (berbamine derivative) |
Cell viability- determination of IC50 value |
MTS Assay |
N/A N/A |
A2058 |
Homo sapiens |
|
|
|
| BBMD3 (berbamine derivative) |
Cell viability- determination of IC50 value |
MTS Assay |
N/A N/A |
DU145 |
Homo sapiens |
|
|
|
| BBMD3 (berbamine derivative) |
Cell viability |
ELISA |
1.00 µM |
A2058 |
Homo sapiens |
|
|
|
| BBMD3 (berbamine derivative) |
Cell viability |
ELISA |
2.00 µM |
A2058 |
Homo sapiens |
|
|
|
| BBMD3 (berbamine derivative) |
Cell viability |
ELISA |
3.00 µM |
A2058 |
Homo sapiens |
|
|
|
| BBMD3 (berbamine derivative) |
Cell viability |
ELISA |
4.00 µM |
A2058 |
Homo sapiens |
|
|
|
| BBMD3 (berbamine derivative) |
Cell viability |
ELISA |
5.00 µM |
A2058 |
Homo sapiens |
|
|
|
| BBMD3 (berbamine derivative) |
Cell viability |
ELISA |
10.00 µM |
A2058 |
Homo sapiens |
|
|
|
| BBMD3 (berbamine derivative) |
Cell viability |
ELISA |
1.00 µM |
A375 |
Homo sapiens |
|
|
|
| BBMD3 (berbamine derivative) |
Cell viability |
ELISA |
2.00 µM |
A375 |
Homo sapiens |
|
|
|
| BBMD3 (berbamine derivative) |
Cell viability |
ELISA |
3.00 µM |
A375 |
Homo sapiens |
|
|
|
| BBMD3 (berbamine derivative) |
Cell viability |
ELISA |
4.00 µM |
A375 |
Homo sapiens |
|
|
|
| BBMD3 (berbamine derivative) |
Cell viability |
ELISA |
5.00 µM |
A375 |
Homo sapiens |
|
|
|
| BBMD3 (berbamine derivative) |
Cell viability |
ELISA |
10.00 µM |
A375 |
Homo sapiens |
|
|
|
| BBMD3 (berbamine derivative) |
Cell viability |
ELISA |
1.00 µM |
G361 |
Homo sapiens |
|
|
|
| BBMD3 (berbamine derivative) |
Cell viability |
ELISA |
2.00 µM |
G361 |
Homo sapiens |
|
|
|
| BBMD3 (berbamine derivative) |
Cell viability |
ELISA |
3.00 µM |
G361 |
Homo sapiens |
|
|
|
| BBMD3 (berbamine derivative) |
Cell viability |
ELISA |
4.00 µM |
G361 |
Homo sapiens |
|
|
|
| BBMD3 (berbamine derivative) |
Cell viability |
ELISA |
5.00 µM |
G361 |
Homo sapiens |
|
|
|
| BBMD3 (berbamine derivative) |
Cell viability |
ELISA |
10.00 µM |
G361 |
Homo sapiens |
|
|
|
| BBMD3 (berbamine derivative) |
Cell viability |
ELISA |
1.00 µM |
SK-MEL-28 |
Homo sapiens |
|
|
|
| BBMD3 (berbamine derivative) |
Cell viability |
ELISA |
2.00 µM |
SK-MEL-28 |
Homo sapiens |
|
|
|
| BBMD3 (berbamine derivative) |
Cell viability |
ELISA |
3.00 µM |
SK-MEL-28 |
Homo sapiens |
|
|
|
| BBMD3 (berbamine derivative) |
Cell viability |
ELISA |
4.00 µM |
SK-MEL-28 |
Homo sapiens |
|
|
|
| BBMD3 (berbamine derivative) |
Cell viability |
ELISA |
5.00 µM |
SK-MEL-28 |
Homo sapiens |
|
|
|
| BBMD3 (berbamine derivative) |
Cell viability |
ELISA |
10.00 µM |
SK-MEL-28 |
Homo sapiens |
|
|
|
| BBMD3 (berbamine derivative) |
Cell viability |
ELISA |
1.00 µM |
SK-MEL-5 |
Homo sapiens |
|
|
|
| BBMD3 (berbamine derivative) |
Cell viability |
ELISA |
2.00 µM |
SK-MEL-5 |
Homo sapiens |
|
|
|
| BBMD3 (berbamine derivative) |
Cell viability |
ELISA |
3.00 µM |
SK-MEL-5 |
Homo sapiens |
|
|
|
| BBMD3 (berbamine derivative) |
Cell viability |
ELISA |
4.00 µM |
SK-MEL-5 |
Homo sapiens |
|
|
|
| BBMD3 (berbamine derivative) |
Cell viability |
ELISA |
5.00 µM |
SK-MEL-5 |
Homo sapiens |
|
|
|
| BBMD3 (berbamine derivative) |
Cell viability |
ELISA |
10.00 µM |
SK-MEL-5 |
Homo sapiens |
|
|
|
| BBMD3 (berbamine derivative) |
Cell viability |
MTS Assay |
0.10 µM |
NHDF |
Homo sapiens |
|
|
|
| BBMD3 (berbamine derivative) |
Cell viability |
MTS Assay |
0.50 µM |
NHDF |
Homo sapiens |
|
|
|
| BBMD3 (berbamine derivative) |
Cell viability |
MTS Assay |
1.00 µM |
NHDF |
Homo sapiens |
|
|
|
| BBMD3 (berbamine derivative) |
Cell viability |
MTS Assay |
5.00 µM |
NHDF |
Homo sapiens |
|
|
|
| BBMD3 (berbamine derivative) |
Cell viability |
MTS Assay |
10.00 µM |
NHDF |
Homo sapiens |
|
|
|
| BBMD3 (berbamine derivative) |
Cell viability |
MTS Assay |
20.00 µM |
NHDF |
Homo sapiens |
|
|
|
| BBMD3 (berbamine derivative) |
Inhibition of Jak/STAT signalling |
Western Blot |
10.00 µM |
A2058 |
Homo sapiens |
|
p-STAT3 |
|
| BBMD3 (berbamine derivative) |
Inhibition of Jak/STAT signalling |
Western Blot |
10.00 µM |
A375 |
Homo sapiens |
|
p-STAT3 |
|
| BBMD3 (berbamine derivative) |
Inhibition of Jak/STAT signalling |
Western Blot |
10.00 µM |
G361 |
Homo sapiens |
|
p-STAT3 |
|
