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Experiments

Compound Investigated event Experiment type Concentration Cell line Organism Animal model Stat protein Details
AZD1480 Influence on protein activity in presence of OSM Western Blot 1.00 µM U251-MG Homo sapiens
AZD1480 Influence on protein activity in presence of OSM Western Blot 10.00 µM U251-MG Homo sapiens
AZD1480 Influence on protein activity in presence of OSM Western Blot 0.10 µM U251-MG Homo sapiens
AZD1480 Influence on protein activity in presence of OSM Western Blot 0.50 µM U251-MG Homo sapiens
AZD1480 Influence on protein activity in presence of OSM Western Blot 1.00 µM U251-MG Homo sapiens
AZD1480 Influence on protein activity in presence of OSM Western Blot 10.00 µM U251-MG Homo sapiens
AZD1480 Influence on protein activity in presence of OSM Western Blot 0.10 µM U87-MG Homo sapiens
AZD1480 Influence on protein activity in presence of OSM Western Blot 0.50 µM U87-MG Homo sapiens
AZD1480 Influence on protein activity in presence of OSM Western Blot 1.00 µM U87-MG Homo sapiens
AZD1480 Influence on protein activity in presence of OSM Western Blot 10.00 µM U87-MG Homo sapiens
AZD1480 Influence on protein activity in presence of OSM Western Blot 0.10 µM 4C8 Homo sapiens
AZD1480 Influence on protein activity in presence of OSM Western Blot 0.50 µM 4C8 Homo sapiens
AZD1480 Influence on protein activity in presence of OSM Western Blot 1.00 µM 4C8 Homo sapiens
AZD1480 Influence on protein activity in presence of OSM Western Blot 10.00 µM 4C8 Homo sapiens
AZD1480 Influence on protein activity in presence of OSM Western Blot 0.10 µM U251-MG Homo sapiens
AZD1480 Influence on protein activity in presence of OSM Western Blot 0.50 µM U251-MG Homo sapiens
AZD1480 Influence on protein activity in presence of OSM Western Blot 1.00 µM U251-MG Homo sapiens
AZD1480 Influence on protein activity in presence of OSM Western Blot 10.00 µM U251-MG Homo sapiens
AZD1480 Influence on downstream gene transcription RT-qPCR 1.00 µM U251-MG Homo sapiens
AZD1480 Influence on downstream gene transcription RT-qPCR 1.00 µM U87-MG Homo sapiens
AZD1480 Influence on downstream gene transcription RT-qPCR 1.00 µM 4C8 Homo sapiens
AZD1480 Influence on downstream gene transcription RT-qPCR 1.00 µM U251-MG Homo sapiens
AZD1480 Influence on downstream gene transcription RT-qPCR 1.00 µM U87-MG Homo sapiens
AZD1480 Influence on downstream gene transcription RT-qPCR 1.00 µM 4C8 Homo sapiens
AZD1480 Influence on downstream gene transcription RT-qPCR 1.00 µM U251-MG Homo sapiens
AZD1480 Influence on downstream gene transcription RT-qPCR 1.00 µM U87-MG Homo sapiens
AZD1480 Influence on downstream gene transcription RT-qPCR 1.00 µM 4C8 Homo sapiens
AZD1480 Influence on protein activity in tumor tissue in presence of OSM Western Blot 0.10 µM Xenograft X1066 Mus musculus athymic nude mice p-STAT3 (Y705)
AZD1480 Influence on protein activity in tumor tissue in presence of OSM Western Blot 0.50 µM Xenograft X1066 Mus musculus athymic nude mice p-STAT3 (Y705)
AZD1480 Influence on protein activity in tumor tissue in presence of OSM Western Blot 1.00 µM Xenograft X1066 Mus musculus athymic nude mice p-STAT3 (Y705)
AZD1480 Influence on protein activity in tumor tissue in presence of OSM Western Blot 10.00 µM Xenograft X1066 Mus musculus athymic nude mice p-STAT3 (Y705)
AZD1480 Influence on protein activity in tumor tissue in presence of OSM Western Blot 0.10 µM Xenograft X1066 Mus musculus athymic nude mice STAT3
AZD1480 Influence on protein activity in tumor tissue in presence of OSM Western Blot 0.50 µM Xenograft X1066 Mus musculus athymic nude mice STAT3
AZD1480 Influence on protein activity in tumor tissue in presence of OSM Western Blot 1.00 µM Xenograft X1066 Mus musculus athymic nude mice STAT3
AZD1480 Influence on protein activity in tumor tissue in presence of OSM Western Blot 10.00 µM Xenograft X1066 Mus musculus athymic nude mice STAT3
AZD1480 Influence on protein activity in tumor tissue in presence of OSM Western Blot 0.10 µM Xenograft X1066 Mus musculus athymic nude mice
AZD1480 Influence on protein activity in tumor tissue in presence of OSM Western Blot 0.50 µM Xenograft X1066 Mus musculus athymic nude mice
AZD1480 Influence on protein activity in tumor tissue in presence of OSM Western Blot 1.00 µM Xenograft X1066 Mus musculus athymic nude mice
AZD1480 Influence on protein activity in tumor tissue in presence of OSM Western Blot 10.00 µM Xenograft X1066 Mus musculus athymic nude mice
AZD1480 Influence on protein activity in tumor tissue in presence of OSM Western Blot 0.10 µM Xenograft X1066 Mus musculus athymic nude mice
AZD1480 Influence on protein activity in tumor tissue in presence of OSM Western Blot 0.50 µM Xenograft X1066 Mus musculus athymic nude mice
AZD1480 Influence on protein activity in tumor tissue in presence of OSM Western Blot 1.00 µM Xenograft X1066 Mus musculus athymic nude mice
AZD1480 Influence on protein activity in tumor tissue in presence of OSM Western Blot 10.00 µM Xenograft X1066 Mus musculus athymic nude mice
AZD1480 Influence on protein activity in tumor tissue in presence of OSM Western Blot 0.10 µM Xenograft X1066 Mus musculus athymic nude mice
AZD1480 Influence on protein activity in tumor tissue in presence of OSM Western Blot 0.50 µM Xenograft X1066 Mus musculus athymic nude mice
AZD1480 Influence on protein activity in tumor tissue in presence of OSM Western Blot 1.00 µM Xenograft X1066 Mus musculus athymic nude mice
AZD1480 Influence on protein activity in tumor tissue in presence of OSM Western Blot 10.00 µM Xenograft X1066 Mus musculus athymic nude mice
AZD1480 Influence on protein activity in tumor tissue in presence of OSM Western Blot 0.10 µM Xenograft X1066 Mus musculus athymic nude mice
AZD1480 Influence on protein activity in tumor tissue in presence of OSM Western Blot 0.50 µM Xenograft X1066 Mus musculus athymic nude mice
AZD1480 Influence on protein activity in tumor tissue in presence of OSM Western Blot 1.00 µM Xenograft X1066 Mus musculus athymic nude mice