AZD1480

Name Value
Weight 348.770 g/mol
Zinc ID ZINC58631551
Smiles Cc1cc(Nc2nc(N[C@@H](C)c3ncc(F)cn3)ncc2Cl)[nH]n1
Molecular formula C14H14ClFN8
Mode of inhibition Direct JAK2; Indirect STAT3
CAS 935666-88-9

Clinical Trials

Study title Status Conditions Link
A Phase I Study of AZD1480 in Patients With Advanced Solid Malignancies and Advanced Hepatocellular Carcinoma in the Escalation Phase,Non-Small Cell Lung Cancer(NSCLC) and Non-smokers With Lung Metastasis and Gastric Cancer and Solid Tumour in the Expansion Phase. Terminated Solid Tumour|Advanced Solid Malignancies|Child-Pugh A to B7 Advanced Hepatocellular Carcinoma|EGFR and/or ROS Mutant NSCLC|Lung Metastasis Carcinoma|Gastric Cancer NCT01219543
Study to Assess Safety, Tolerability and PK of AZD1480 in Patients With Solid Tumours Terminated Solid Malignancies NCT01112397
Study to Assess the Safety of AZD1480 in Patients With Myeloproliferative Diseases Completed Primary Myelofibrosis (PMF)|Post-Polycythaemia Vera|Essential Thrombocythaemia Myelofibrosis NCT00910728

References

Publication DOI Pubmed PMCID
Inhibition of STAT3 with orally active JAK inhibitor, AZD1480, decreases tumor growth in Neuroblastoma and Pediatric Sarcomas In vitro and In vivo. Oncotarget Shuang Yan, Zhijie Li, Carol J Thiele, 4, 3, None, None, 10.18632/oncotarget.930 10.18632/oncotarget.930 23531921 PMC3717306
AZD1480 delays tumor growth in a melanoma model while enhancing the suppressive activity of myeloid-derived suppressor cells. Oncotarget Sarah K Maenhout, Stephanie Du Four, Jurgen Corthals, Bart Neyns, Kris Thielemans, Joeri L Aerts, 5, 16, 2014-08-30, None, 10.18632/oncotarget.2254 10.18632/oncotarget.2254 25149535 PMC4196164
The JAK inhibitor AZD1480 regulates proliferation and immunity in Hodgkin lymphoma 10.1038/bcj.2011.46 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3255510/ N/A
JAK1/2 Inhibitors AZD1480 and CYT387 Inhibit Canine B-Cell Lymphoma Growth by Increasing Apoptosis and Disrupting Cell Proliferation. Journal of veterinary internal medicine Z Lu, C C Hong, P C Jark, A L F V Assumpção, N Bollig, G Kong, X Pan, 31, 6, None, 2017-09-27, 10.1111/jvim.14837 10.1111/jvim.14837 28960447 PMC5697192
Evolution. Pruning the tree of life. Nature M J Benton, 342, 6246, 1989-11-09, None, 10.1016/j.ccr.2009.10.015 10.1016/j.ccr.2009.10.015 2812011 PMC2812011
AZD1480 blocks growth and tumorigenesis of RET- activated thyroid cancer cell lines. PloS one Joana P Couto, Ana Almeida, Laura Daly, Manuel Sobrinho-Simões, Jacqueline F Bromberg, Paula Soares, 7, 10, None, 2012-10-02, 0.1371/journal.pone.0046869 0.1371/journal.pone.0046869 23056499 PMC3462763
Antiangiogenic and antimetastatic activity of JAK inhibitor AZD1480. Cancer research Hong Xin, Andreas Herrmann, Karen Reckamp, Wang Zhang, Sumanta Pal, Michael Hedvat, Chunyan Zhang, Wei Liang, Anna Scuto, Shaobu Weng, Deborah Morosini, Zhu A Cao, Michael Zinda, Robert Figlin, Dennis Huszar, Richard Jove, Hua Yu, 71, 21, 2011-11-01, 2011-09-15, 10.1158/0008-5472.CAN-11-1217 10.1158/0008-5472.CAN-11-1217 21920898 PMC3206173
The novel JAK inhibitor AZD1480 blocks STAT3 and FGFR3 signaling, resulting in suppression of human myeloma cell growth and survival 10.1038/leu.2010.289 https://www.ncbi.nlm.nih.gov/pubmed/21164517 N/A
Therapeutic potential of AZD1480 for the treatment of human glioblastoma. Molecular cancer therapeutics Braden C McFarland, Jing-Yuan Ma, Catherine P Langford, G Yancey Gillespie, Hao Yu, Ying Zheng, Susan E Nozell, Dennis Huszar, Etty N Benveniste, 10, 12, None, 2011-10-25, 10.1158/1535-7163.MCT-11-0480 10.1158/1535-7163.MCT-11-0480 22027691 PMC3237864
Evaluation of the in vitro and in vivo efficacy of the JAK inhibitor AZD1480 against JAK-mutated acute lymphoblastic leukemia. Molecular cancer therapeutics Santi Suryani, Lauryn S Bracken, Richard C Harvey, Keith C S Sia, Hernan Carol, I-Ming Chen, Kathryn Evans, Philipp A Dietrich, Kathryn G Roberts, Raushan T Kurmasheva, Catherine A Billups, Charles G Mullighan, Cheryl L Willman, Mignon L Loh, Stephen P Hunger, Peter J Houghton, Malcolm A Smith, Richard B Lock, 14, 2, None, 2014-12-10, 10.1158/1535-7163.MCT-14-0647 10.1158/1535-7163.MCT-14-0647 25504635 PMC4326541
On the meaning of vesiculation in capillary endothelium. Angiologica J Wolff, 4, 1, None, None, 10.1158/1078-0432.CCR-13-0422 10.1158/1078-0432.CCR-13-0422 6021137 PMC6021137
Therapeutic efficacy of suppressing the Jak/STAT pathway in multiple models of experimental autoimmune encephalomyelitis. Journal of immunology (Baltimore, Md. : 1950) Yudong Liu, Andrew T Holdbrooks, Patrizia De Sarno, Amber L Rowse, Lora L Yanagisawa, Braden C McFarland, Laurie E Harrington, Chander Raman, Steffanie Sabbaj, Etty N Benveniste, Hongwei Qin, 192, 1, 2014-01-01, 2013-12-09, 10.4049/jimmunol.1301513 10.4049/jimmunol.1301513 24323580 PMC3934829
Formate assay in body fluids: application in methanol poisoning. Biochemical medicine A B Makar, K E McMartin, M Palese, T R Tephly, 13, 2, None, None, 10.1002/pbc.25175. 10.1002/pbc.25175. 1 PMC4201390

Vendors

Company Lnk to product
Selleckchem https://www.selleckchem.com/products/AZD1480.html
Tocris https://www.tocris.com/products/azd-1480_5617
MERCK (Sigma Aldrich) https://www.sigmaaldrich.com/catalog/product/sigma/sml1505?lang=pl&region=PL
MedChemExpress https://www.medchemexpress.com/AZD-1480.html
Caymanchemical https://www.caymanchem.com/product/10702/azd1480
TargetMol https://www.targetmol.com/compound/AZD1480
AK Scientific Inc. https://aksci.com/item_list.php?search=azd1480
Apollo Scientific http://www.apolloscientific.co.uk/display_item.php?id=145977
BLDpharm https://www.bldpharm.com/products/935666-88-9.html

Filter data

Compound AZD1480
Experiment types , AlamarBlue assay, Caspase 3/7 activity, Cell survival assay, Cell-free kinase assay; Western Blot, DIMSCAN, DIMSCAN analysis, ELISA, EMSA, FACS, Flow cytometr- annexin V staining , Flow cytometr- propodium iodide staining, Flow cytometry , Flow cytometry- annexin V staining, Fluorometric immunosorbent enzyme assay, Function of myeloid-derived suppressor cells, Griess, HEMAVET, Hematoxylin-eosin staining, Histological staining, Immunization, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Immunostaining , Ki67/DAPI cell proliferation assay, Luciferase Reporter Gene Assay , MTS, MTS Assay , Number of nodules, Quantitative RT-PCR, RT-qPCR, Real Time PCR, SRB assay , Soft Agar Growth Assay, Survival Rate, TUNEL, Trypan blue exclusion assay, Tube formation assay , Tumer volume , Tumor volume, Tumor weight, Tumour volume , WST-1 Cell Proliferation Assay, Western Blot
Concentrations 0.00, 0.01, 0.03, 0.05, 0.10, 0.20, 0.25, 0.30, 0.50, 0.75, 0.80, 1.00, 1.25, 1.50, 1.75, 10.00, 100.00, 1000.00, 15.00, 2.00, 2.40, 2.50, 20.00, 200.00, 25.00, 250.00, 3.00, 30.00, 300.00, 4.00, 400.00, 5.00, 50.00, 500.00, 60.00, 800.00, N/A
Cell lines 1087-mel, 4C8, 786-O, AGS, ARPE19, AS, BE2, BMDM, BT-12, Ba/F3 TEL-JAK1, Ba/F3 TEL-JAK2, Ba/F3 TEL-JAK3, Ba/F3 TEL-TYK2, CCRF-CEM GM, CCRF-CEM-SY, CD 8+ T cells, CD4+T, CHLA-10, CHLA-136, CHLA-258, CHLA-266, CHLA-9, CHLA-90, CLBL-1, COG-LL-317, CWR22Pc, CWR22Rv1, DCs, DU145, DU145 (xenograft), EC, HB-1643, HCC 827, HD-LM2, HEK293, HS-5, HUVEC, Hep3B, IMR32, K1735-C4, KCNR, KCNR (xenograft), KM-H2, KT-10, KT-11, KT-13, KT-6, KT-8, Karpas-299, Kasumi-1, Kms.11, Kms.11 (xenograft), L-428, L-540, LAN5, LN-17, LYM, MDA-MB-468, MDA-MB-468 (xenograft), MDAH2774, MDAH2774 (xenograft), MDCK, MEF-Stat3-YFP, MO4, MO4 (xenograft), MOLt-4, MONO, MZ-CRC1, Murine Primary Astrocytes, NALM-6, NB-EBc1, NCI-H1650, NEU, NGP, OCL-LY7, PAKHZT (xenograft), PAKRSL, PAKRSL (xenograft), PAKYEP (xenograft), PALJDL, PALJDL (xenograft), PALLSD (xenograft), PALNTB (xenograft), PAMDRM (xenograft), PBMC, PC-3, PCCI3, PCCl3-RET/PTC3, RBC, RD, RPMI 8226, RS4;11, Ramos-RA1, Renca, Renca (xenograft0, Rh18, Rh18 (xenograft), Rh30, Rh41, SJ-GBM2, SY5Y, SY5Y (xenograft), Splenocytes, TC-71, TC32, TC32 (xenograft), TPC-1, TPC-1 (xenograft), TT, Th1, U251-MG, U266, U87-MG, WBC, Xenograft X1016, Xenograft X1046, Xenograft X1066, spinal cord
Organisms Canis lupus familiaris, Homo sapiens, Mus musclus, Mus musculus, Rattus norvegicus
Animal models BALB/c, NOD/SCID IL2Rγ-null mice, athymic nude mice, c57BL/6, nu/nu Nude mice, patient 1, patient 2, patient 3
STAT proteins STAT1, STAT3, STAT3:STAT3, STAT4, STAT5, STAT5A, STAT5B, STAT6, p-STAT1, p-STAT3, p-STAT3 (Y705), p-STAT5, p-STAT6
Other AKT, AR splice variant, AURORA A, Actin, Bcl-2, Bcl-XL, Bcl-xL, CD133, CD31, Caspase 3, Caspase 9, Caspase-3, Cdc25A, Cyclin A, Cyclin D1, Cyclin D2, Cyclin D3, Cyclin-D2, ERK, ERK1/2, FGFR3:FGFR3, FGFR3:p-Tyr, FL AR, GAPDH, Histone H3, IFNγ, IL-12p40, IL-13, IL-23p19, IL-6, JAK1, JAK1:JAK1, JAK1:p-JAK1, JAK2, JAK2:JAK2, JAK2:p-JAK2, JAK3, Jak1, Jak2, Ki67, MAPK, MEK1/2, MMP-9, MMP9, Mcl-1, Meca-32, Myc, P38, P65, PARP, PD-L1, PD-L2, PSA, S6, SHP2, SOCS3, Survivin, TARC, TIMP-1, TUNEL, TYK2, VEGF, c-Myc, p-AKT, p-AKT (S473), p-AURORA A, p-ERK, p-ERK1/2, p-ERK1/2(T202/Y204), p-Histone 3, p-JAK1 (Y1022/1023), p-JAK2, p-JAK2 (Y1007/1008), p-JAK2 (Y1007/1008)*, p-JAK2 (Y1007/10080, p-JAK3 (Y980), p-MAPK (T202/Y204), p-MEK1/2, p-P38, p-RET (Y1062), p-S6 (S235/236), p-SHP2 (Y542), p-TYK2 (Y1054/1055), p27, p44/42 MAPK, p44/42 pMAPK, β-actin

Experiments

Compound Experiment type Investigated event Concentration Cell line Organism Animal model Stat protein Details
AZD1480 Flow cytometr- propodium iodide staining Influence on cell cycle 0.50 µM ARPE19 Homo sapiens
AZD1480 Flow cytometr- propodium iodide staining Influence on cell cycle 1.00 µM ARPE19 Homo sapiens
AZD1480 Flow cytometr- propodium iodide staining Influence on cell cycle 2.00 µM ARPE19 Homo sapiens
AZD1480 Flow cytometr- propodium iodide staining Influence on cell cycle 0.50 µM KCNR Homo sapiens
AZD1480 Flow cytometr- propodium iodide staining Influence on cell cycle 1.00 µM KCNR Homo sapiens
AZD1480 Flow cytometr- propodium iodide staining Influence on cell cycle 2.00 µM KCNR Homo sapiens
AZD1480 Flow cytometr- propodium iodide staining Influence on cell cycle 0.50 µM SY5Y Homo sapiens
AZD1480 Flow cytometr- propodium iodide staining Influence on cell cycle 1.00 µM SY5Y Homo sapiens
AZD1480 Flow cytometr- propodium iodide staining Influence on cell cycle 2.00 µM SY5Y Homo sapiens
AZD1480 Flow cytometr- propodium iodide staining Influence on cell cycle 0.50 µM Rh18 Homo sapiens
AZD1480 Flow cytometr- propodium iodide staining Influence on cell cycle 1.00 µM Rh18 Homo sapiens
AZD1480 Flow cytometr- propodium iodide staining Influence on cell cycle 2.00 µM Rh18 Homo sapiens
AZD1480 Flow cytometr- propodium iodide staining Influence on cell cycle 0.50 µM TC32 Homo sapiens
AZD1480 Flow cytometr- propodium iodide staining Influence on cell cycle 1.00 µM TC32 Homo sapiens
AZD1480 Flow cytometr- propodium iodide staining Influence on cell cycle 2.00 µM TC32 Homo sapiens
AZD1480 MTS Assay Influence on cell proliferation N/A N/A ARPE19 Homo sapiens
AZD1480 MTS Assay Influence on cell proliferation N/A N/A HEK293 Homo sapiens
AZD1480 MTS Assay Influence on cell proliferation N/A N/A KCNR Homo sapiens
AZD1480 MTS Assay Influence on cell proliferation N/A N/A SY5Y Homo sapiens
AZD1480 MTS Assay Influence on cell proliferation N/A N/A BE2 Homo sapiens
AZD1480 MTS Assay Influence on cell proliferation N/A N/A AS Homo sapiens
AZD1480 MTS Assay Influence on cell proliferation N/A N/A NGP Homo sapiens
AZD1480 MTS Assay Influence on cell proliferation N/A N/A IMR32 Homo sapiens
AZD1480 MTS Assay Influence on cell proliferation N/A N/A LAN5 Homo sapiens
AZD1480 Caspase 3/7 activity Influence on cell apoptosis 0.50 µM ARPE19 Homo sapiens
AZD1480 Caspase 3/7 activity Influence on cell apoptosis 1.00 µM ARPE19 Homo sapiens
AZD1480 Caspase 3/7 activity Influence on cell apoptosis 2.50 µM ARPE19 Homo sapiens
AZD1480 Caspase 3/7 activity Influence on cell apoptosis 0.50 µM HEK293 Homo sapiens
AZD1480 Caspase 3/7 activity Influence on cell apoptosis 1.00 µM HEK293 Homo sapiens
AZD1480 Caspase 3/7 activity Influence on cell apoptosis 2.50 µM HEK293 Homo sapiens
AZD1480 Caspase 3/7 activity Influence on cell apoptosis 0.50 µM KCNR Homo sapiens
AZD1480 Caspase 3/7 activity Influence on cell apoptosis 1.00 µM KCNR Homo sapiens
AZD1480 Caspase 3/7 activity Influence on cell apoptosis 2.50 µM KCNR Homo sapiens
AZD1480 Caspase 3/7 activity Influence on cell apoptosis 0.50 µM SY5Y Homo sapiens
AZD1480 Caspase 3/7 activity Influence on cell apoptosis 1.00 µM SY5Y Homo sapiens
AZD1480 Caspase 3/7 activity Influence on cell apoptosis 2.50 µM SY5Y Homo sapiens
AZD1480 Caspase 3/7 activity Influence on cell apoptosis 0.50 µM Rh18 Homo sapiens
AZD1480 Caspase 3/7 activity Influence on cell apoptosis 1.00 µM Rh18 Homo sapiens
AZD1480 Caspase 3/7 activity Influence on cell apoptosis 2.50 µM Rh18 Homo sapiens
AZD1480 Caspase 3/7 activity Influence on cell apoptosis 0.50 µM TC32 Homo sapiens
AZD1480 Caspase 3/7 activity Influence on cell apoptosis 1.00 µM TC32 Homo sapiens
AZD1480 Caspase 3/7 activity Influence on cell apoptosis 2.50 µM TC32 Homo sapiens
AZD1480 Cell survival assay Influence on cell apoptosis 0.50 µM KCNR
AZD1480 Cell survival assay Influence on cell apoptosis 0.50 µM SY5Y
AZD1480 Cell survival assay Influence on cell apoptosis 0.50 µM Rh18
AZD1480 Cell survival assay Influence on cell apoptosis 0.50 µM TC32
AZD1480 Western Blot Influence on protein activity 0.50 µM KCNR Homo sapiens p-STAT3 (Y705)
AZD1480 Western Blot Influence on protein activity 1.00 µM KCNR Homo sapiens p-STAT3 (Y705)
AZD1480 Western Blot Influence on protein activity 2.50 µM KCNR Homo sapiens p-STAT3 (Y705)
AZD1480 Western Blot Influence on protein activity 5.00 µM KCNR Homo sapiens p-STAT3 (Y705)
AZD1480 Western Blot Influence on protein activity 0.50 µM KCNR Homo sapiens STAT3
AZD1480 Western Blot Influence on protein activity 1.00 µM KCNR Homo sapiens STAT3
AZD1480 Western Blot Influence on protein activity 2.50 µM KCNR Homo sapiens STAT3
AZD1480 Western Blot Influence on protein activity 5.00 µM KCNR Homo sapiens STAT3
AZD1480 Western Blot Influence on protein activity 0.50 µM SY5Y Homo sapiens p-STAT3 (Y705)
AZD1480 Western Blot Influence on protein activity 1.00 µM SY5Y Homo sapiens p-STAT3 (Y705)
AZD1480 Western Blot Influence on protein activity 2.50 µM SY5Y Homo sapiens p-STAT3 (Y705)
AZD1480 Western Blot Influence on protein activity 5.00 µM SY5Y Homo sapiens p-STAT3 (Y705)
AZD1480 Western Blot Influence on protein activity 0.50 µM SY5Y Homo sapiens STAT3
AZD1480 Western Blot Influence on protein activity 1.00 µM SY5Y Homo sapiens STAT3
AZD1480 Western Blot Influence on protein activity 2.50 µM SY5Y Homo sapiens STAT3
AZD1480 Western Blot Influence on protein activity 5.00 µM SY5Y Homo sapiens STAT3
AZD1480 Western Blot Influence on protein activity 0.50 µM Rh18 Homo sapiens p-STAT3 (Y705)
AZD1480 Western Blot Influence on protein activity 1.00 µM Rh18 Homo sapiens p-STAT3 (Y705)
AZD1480 Western Blot Influence on protein activity 2.50 µM Rh18 Homo sapiens p-STAT3 (Y705)
AZD1480 Western Blot Influence on protein activity 5.00 µM Rh18 Homo sapiens p-STAT3 (Y705)
AZD1480 Western Blot Influence on protein activity 0.50 µM Rh18 Homo sapiens STAT3
AZD1480 Western Blot Influence on protein activity 1.00 µM Rh18 Homo sapiens STAT3
AZD1480 Western Blot Influence on protein activity 2.50 µM Rh18 Homo sapiens STAT3
AZD1480 Western Blot Influence on protein activity 5.00 µM Rh18 Homo sapiens STAT3
AZD1480 Western Blot Influence on protein activity 0.50 µM TC32 Homo sapiens p-STAT3 (Y705)
AZD1480 Western Blot Influence on protein activity 1.00 µM TC32 Homo sapiens p-STAT3 (Y705)
AZD1480 Western Blot Influence on protein activity 2.50 µM TC32 Homo sapiens p-STAT3 (Y705)
AZD1480 Western Blot Influence on protein activity 5.00 µM TC32 Homo sapiens p-STAT3 (Y705)
AZD1480 Western Blot Influence on protein activity 0.50 µM TC32 Homo sapiens STAT3
AZD1480 Western Blot Influence on protein activity 1.00 µM TC32 Homo sapiens STAT3
AZD1480 Western Blot Influence on protein activity 2.50 µM TC32 Homo sapiens STAT3
AZD1480 Western Blot Influence on protein activity 5.00 µM TC32 Homo sapiens STAT3
AZD1480 Western Blot Influence on protein activity 0.50 µM KCNR Homo sapiens
AZD1480 Western Blot Influence on protein activity 1.00 µM KCNR Homo sapiens
AZD1480 Western Blot Influence on protein activity 2.50 µM KCNR Homo sapiens
AZD1480 Western Blot Influence on protein activity 5.00 µM KCNR Homo sapiens
AZD1480 Western Blot Influence on protein activity 0.50 µM KCNR Homo sapiens
AZD1480 Western Blot Influence on protein activity 1.00 µM KCNR Homo sapiens
AZD1480 Western Blot Influence on protein activity 2.50 µM KCNR Homo sapiens
AZD1480 Western Blot Influence on protein activity 5.00 µM KCNR Homo sapiens
AZD1480 Western Blot Influence on protein activity 0.50 µM KCNR Homo sapiens
AZD1480 Western Blot Influence on protein activity 1.00 µM KCNR Homo sapiens
AZD1480 Western Blot Influence on protein activity 2.50 µM KCNR Homo sapiens
AZD1480 Western Blot Influence on protein activity 5.00 µM KCNR Homo sapiens
AZD1480 Western Blot Influence on protein activity 0.50 µM SY5Y Homo sapiens
AZD1480 Western Blot Influence on protein activity 1.00 µM SY5Y Homo sapiens
AZD1480 Western Blot Influence on protein activity 2.50 µM SY5Y Homo sapiens
AZD1480 Western Blot Influence on protein activity 5.00 µM SY5Y Homo sapiens
AZD1480 Western Blot Influence on protein activity 0.50 µM SY5Y Homo sapiens
AZD1480 Western Blot Influence on protein activity 1.00 µM SY5Y Homo sapiens
AZD1480 Western Blot Influence on protein activity 2.50 µM SY5Y Homo sapiens
AZD1480 Western Blot Influence on protein activity 5.00 µM SY5Y Homo sapiens
AZD1480 Western Blot Influence on protein activity 0.50 µM SY5Y Homo sapiens
AZD1480 Western Blot Influence on protein activity 1.00 µM SY5Y Homo sapiens
AZD1480 Western Blot Influence on protein activity 2.50 µM SY5Y Homo sapiens
AZD1480 Western Blot Influence on protein activity 5.00 µM SY5Y Homo sapiens
AZD1480 Western Blot Influence on protein activity 0.50 µM Rh18 Homo sapiens
AZD1480 Western Blot Influence on protein activity 1.00 µM Rh18 Homo sapiens
AZD1480 Western Blot Influence on protein activity 2.50 µM Rh18 Homo sapiens
AZD1480 Western Blot Influence on protein activity 5.00 µM Rh18 Homo sapiens
AZD1480 Western Blot Influence on protein activity 0.50 µM Rh18 Homo sapiens
AZD1480 Western Blot Influence on protein activity 1.00 µM Rh18 Homo sapiens
AZD1480 Western Blot Influence on protein activity 2.50 µM Rh18 Homo sapiens
AZD1480 Western Blot Influence on protein activity 5.00 µM Rh18 Homo sapiens
AZD1480 Western Blot Influence on protein activity 0.50 µM Rh18 Homo sapiens
AZD1480 Western Blot Influence on protein activity 1.00 µM Rh18 Homo sapiens
AZD1480 Western Blot Influence on protein activity 2.50 µM Rh18 Homo sapiens
AZD1480 Western Blot Influence on protein activity 5.00 µM Rh18 Homo sapiens
AZD1480 Western Blot Influence on protein activity 0.50 µM TC32 Homo sapiens
AZD1480 Western Blot Influence on protein activity 1.00 µM TC32 Homo sapiens
AZD1480 Western Blot Influence on protein activity 2.50 µM TC32 Homo sapiens
AZD1480 Western Blot Influence on protein activity 5.00 µM TC32 Homo sapiens
AZD1480 Western Blot Influence on protein activity 0.50 µM TC32 Homo sapiens
AZD1480 Western Blot Influence on protein activity 1.00 µM TC32 Homo sapiens
AZD1480 Western Blot Influence on protein activity 2.50 µM TC32 Homo sapiens
AZD1480 Western Blot Influence on protein activity 5.00 µM TC32 Homo sapiens
AZD1480 Western Blot Influence on protein activity 0.50 µM TC32 Homo sapiens
AZD1480 Western Blot Influence on protein activity 1.00 µM TC32 Homo sapiens
AZD1480 Western Blot Influence on protein activity 2.50 µM TC32 Homo sapiens
AZD1480 Western Blot Influence on protein activity 5.00 µM TC32 Homo sapiens
AZD1480 Western Blot Influence on protein activity in presence of IL-6 0.50 µM KCNR Homo sapiens p-STAT3 (Y705)
AZD1480 Western Blot Influence on protein activity in presence of IL-6 1.00 µM KCNR Homo sapiens p-STAT3 (Y705)
AZD1480 Western Blot Influence on protein activity in presence of IL-6 2.50 µM KCNR Homo sapiens p-STAT3 (Y705)
AZD1480 Western Blot Influence on protein activity in presence of IL-6 5.00 µM KCNR Homo sapiens p-STAT3 (Y705)
AZD1480 Western Blot Influence on protein activity in presence of IL-6 0.50 µM KCNR Homo sapiens STAT3
AZD1480 Western Blot Influence on protein activity in presence of IL-6 1.00 µM KCNR Homo sapiens STAT3
AZD1480 Western Blot Influence on protein activity in presence of IL-6 2.50 µM KCNR Homo sapiens STAT3
AZD1480 Western Blot Influence on protein activity in presence of IL-6 5.00 µM KCNR Homo sapiens STAT3
AZD1480 Western Blot Influence on protein activity in presence of IL-6 0.50 µM SY5Y Homo sapiens p-STAT3 (Y705)
AZD1480 Western Blot Influence on protein activity in presence of IL-6 1.00 µM SY5Y Homo sapiens p-STAT3 (Y705)
AZD1480 Western Blot Influence on protein activity in presence of IL-6 2.50 µM SY5Y Homo sapiens p-STAT3 (Y705)
AZD1480 Western Blot Influence on protein activity in presence of IL-6 5.00 µM SY5Y Homo sapiens p-STAT3 (Y705)
AZD1480 Western Blot Influence on protein activity in presence of IL-6 0.50 µM SY5Y Homo sapiens STAT3
AZD1480 Western Blot Influence on protein activity in presence of IL-6 1.00 µM SY5Y Homo sapiens STAT3
AZD1480 Western Blot Influence on protein activity in presence of IL-6 2.50 µM SY5Y Homo sapiens STAT3
AZD1480 Western Blot Influence on protein activity in presence of IL-6 5.00 µM SY5Y Homo sapiens STAT3
AZD1480 Western Blot Influence on protein activity in presence of IL-6 0.50 µM Rh18 Homo sapiens p-STAT3 (Y705)
AZD1480 Western Blot Influence on protein activity in presence of IL-6 1.00 µM Rh18 Homo sapiens p-STAT3 (Y705)
AZD1480 Western Blot Influence on protein activity in presence of IL-6 2.50 µM Rh18 Homo sapiens p-STAT3 (Y705)
AZD1480 Western Blot Influence on protein activity in presence of IL-6 5.00 µM Rh18 Homo sapiens p-STAT3 (Y705)
AZD1480 Western Blot Influence on protein activity in presence of IL-6 0.50 µM Rh18 Homo sapiens STAT3
AZD1480 Western Blot Influence on protein activity in presence of IL-6 1.00 µM Rh18 Homo sapiens STAT3
AZD1480 Western Blot Influence on protein activity in presence of IL-6 2.50 µM Rh18 Homo sapiens STAT3
AZD1480 Western Blot Influence on protein activity in presence of IL-6 5.00 µM Rh18 Homo sapiens STAT3
AZD1480 Western Blot Influence on protein activity in presence of IL-6 0.50 µM TC32 Homo sapiens p-STAT3 (Y705)
AZD1480 Western Blot Influence on protein activity in presence of IL-6 1.00 µM TC32 Homo sapiens p-STAT3 (Y705)
AZD1480 Western Blot Influence on protein activity in presence of IL-6 2.50 µM TC32 Homo sapiens p-STAT3 (Y705)
AZD1480 Western Blot Influence on protein activity in presence of IL-6 5.00 µM TC32 Homo sapiens p-STAT3 (Y705)
AZD1480 Western Blot Influence on protein activity in presence of IL-6 0.50 µM TC32 Homo sapiens STAT3
AZD1480 Western Blot Influence on protein activity in presence of IL-6 1.00 µM TC32 Homo sapiens STAT3
AZD1480 Western Blot Influence on protein activity in presence of IL-6 2.50 µM TC32 Homo sapiens STAT3
AZD1480 Western Blot Influence on protein activity in presence of IL-6 5.00 µM TC32 Homo sapiens STAT3
AZD1480 Western Blot Influence on protein activity in presence of IL-6 0.50 µM KCNR Homo sapiens
AZD1480 Western Blot Influence on protein activity in presence of IL-6 1.00 µM KCNR Homo sapiens
AZD1480 Western Blot Influence on protein activity in presence of IL-6 2.50 µM KCNR Homo sapiens
AZD1480 Western Blot Influence on protein activity in presence of IL-6 5.00 µM KCNR Homo sapiens
AZD1480 Western Blot Influence on protein activity in presence of IL-6 0.50 µM KCNR Homo sapiens
AZD1480 Western Blot Influence on protein activity in presence of IL-6 1.00 µM KCNR Homo sapiens
AZD1480 Western Blot Influence on protein activity in presence of IL-6 2.50 µM KCNR Homo sapiens
AZD1480 Western Blot Influence on protein activity in presence of IL-6 5.00 µM KCNR Homo sapiens
AZD1480 Western Blot Influence on protein activity in presence of IL-6 0.50 µM KCNR Homo sapiens
AZD1480 Western Blot Influence on protein activity in presence of IL-6 1.00 µM KCNR Homo sapiens
AZD1480 Western Blot Influence on protein activity in presence of IL-6 2.50 µM KCNR Homo sapiens
AZD1480 Western Blot Influence on protein activity in presence of IL-6 5.00 µM KCNR Homo sapiens
AZD1480 Western Blot Influence on protein activity in presence of IL-6 0.50 µM SY5Y Homo sapiens
AZD1480 Western Blot Influence on protein activity in presence of IL-6 1.00 µM SY5Y Homo sapiens
AZD1480 Western Blot Influence on protein activity in presence of IL-6 2.50 µM SY5Y Homo sapiens
AZD1480 Western Blot Influence on protein activity in presence of IL-6 5.00 µM SY5Y Homo sapiens
AZD1480 Western Blot Influence on protein activity in presence of IL-6 0.50 µM SY5Y Homo sapiens
AZD1480 Western Blot Influence on protein activity in presence of IL-6 1.00 µM SY5Y Homo sapiens
AZD1480 Western Blot Influence on protein activity in presence of IL-6 2.50 µM SY5Y Homo sapiens
AZD1480 Western Blot Influence on protein activity in presence of IL-6 5.00 µM SY5Y Homo sapiens
AZD1480 Western Blot Influence on protein activity in presence of IL-6 0.50 µM SY5Y Homo sapiens
AZD1480 Western Blot Influence on protein activity in presence of IL-6 1.00 µM SY5Y Homo sapiens
AZD1480 Western Blot Influence on protein activity in presence of IL-6 2.50 µM SY5Y Homo sapiens
AZD1480 Western Blot Influence on protein activity in presence of IL-6 5.00 µM SY5Y Homo sapiens
AZD1480 Western Blot Influence on protein activity in presence of IL-6 0.50 µM Rh18 Homo sapiens
AZD1480 Western Blot Influence on protein activity in presence of IL-6 1.00 µM Rh18 Homo sapiens
AZD1480 Western Blot Influence on protein activity in presence of IL-6 2.50 µM Rh18 Homo sapiens
AZD1480 Western Blot Influence on protein activity in presence of IL-6 5.00 µM Rh18 Homo sapiens
AZD1480 Western Blot Influence on protein activity in presence of IL-6 0.50 µM Rh18 Homo sapiens
AZD1480 Western Blot Influence on protein activity in presence of IL-6 1.00 µM Rh18 Homo sapiens
AZD1480 Western Blot Influence on protein activity in presence of IL-6 2.50 µM Rh18 Homo sapiens
AZD1480 Western Blot Influence on protein activity in presence of IL-6 5.00 µM Rh18 Homo sapiens
AZD1480 Western Blot Influence on protein activity in presence of IL-6 0.50 µM Rh18 Homo sapiens
AZD1480 Western Blot Influence on protein activity in presence of IL-6 1.00 µM Rh18 Homo sapiens
AZD1480 Western Blot Influence on protein activity in presence of IL-6 2.50 µM Rh18 Homo sapiens
AZD1480 Western Blot Influence on protein activity in presence of IL-6 5.00 µM Rh18 Homo sapiens
AZD1480 Western Blot Influence on protein activity in presence of IL-6 0.50 µM TC32 Homo sapiens
AZD1480 Western Blot Influence on protein activity in presence of IL-6 1.00 µM TC32 Homo sapiens
AZD1480 Western Blot Influence on protein activity in presence of IL-6 2.50 µM TC32 Homo sapiens
AZD1480 Western Blot Influence on protein activity in presence of IL-6 5.00 µM TC32 Homo sapiens
AZD1480 Western Blot Influence on protein activity in presence of IL-6 0.50 µM TC32 Homo sapiens
AZD1480 Western Blot Influence on protein activity in presence of IL-6 1.00 µM TC32 Homo sapiens
AZD1480 Western Blot Influence on protein activity in presence of IL-6 2.50 µM TC32 Homo sapiens
AZD1480 Western Blot Influence on protein activity in presence of IL-6 5.00 µM TC32 Homo sapiens
AZD1480 Western Blot Influence on protein activity in presence of IL-6 0.50 µM TC32 Homo sapiens
AZD1480 Western Blot Influence on protein activity in presence of IL-6 1.00 µM TC32 Homo sapiens
AZD1480 Western Blot Influence on protein activity in presence of IL-6 2.50 µM TC32 Homo sapiens
AZD1480 Western Blot Influence on protein activity in presence of IL-6 5.00 µM TC32 Homo sapiens
AZD1480 Western Blot Influence on STAT3 downstream genes 0.50 µM KCNR Homo sapiens
AZD1480 Western Blot Influence on STAT3 downstream genes 1.00 µM KCNR Homo sapiens
AZD1480 Western Blot Influence on STAT3 downstream genes 2.50 µM KCNR Homo sapiens
AZD1480 Western Blot Influence on STAT3 downstream genes 5.00 µM KCNR Homo sapiens
AZD1480 Western Blot Influence on STAT3 downstream genes 0.50 µM SY5Y Homo sapiens
AZD1480 Western Blot Influence on STAT3 downstream genes 1.00 µM SY5Y Homo sapiens
AZD1480 Western Blot Influence on STAT3 downstream genes 2.50 µM SY5Y Homo sapiens
AZD1480 Western Blot Influence on STAT3 downstream genes 5.00 µM SY5Y Homo sapiens
AZD1480 Western Blot Influence on STAT3 downstream genes 0.50 µM Rh18 Homo sapiens
AZD1480 Western Blot Influence on STAT3 downstream genes 1.00 µM Rh18 Homo sapiens
AZD1480 Western Blot Influence on STAT3 downstream genes 2.50 µM Rh18 Homo sapiens
AZD1480 Western Blot Influence on STAT3 downstream genes 5.00 µM Rh18 Homo sapiens
AZD1480 Western Blot Influence on STAT3 downstream genes 0.50 µM TC32 Homo sapiens
AZD1480 Western Blot Influence on STAT3 downstream genes 1.00 µM TC32 Homo sapiens
AZD1480 Western Blot Influence on STAT3 downstream genes 2.50 µM TC32 Homo sapiens
AZD1480 Western Blot Influence on STAT3 downstream genes 5.00 µM TC32 Homo sapiens
AZD1480 Western Blot Influence on STAT3 downstream genes 0.50 µM KCNR Homo sapiens
AZD1480 Western Blot Influence on STAT3 downstream genes 1.00 µM KCNR Homo sapiens
AZD1480 Western Blot Influence on STAT3 downstream genes 2.50 µM KCNR Homo sapiens
AZD1480 Western Blot Influence on STAT3 downstream genes 5.00 µM KCNR Homo sapiens
AZD1480 Western Blot Influence on STAT3 downstream genes 0.50 µM SY5Y Homo sapiens
AZD1480 Western Blot Influence on STAT3 downstream genes 1.00 µM SY5Y Homo sapiens
AZD1480 Western Blot Influence on STAT3 downstream genes 2.50 µM SY5Y Homo sapiens
AZD1480 Western Blot Influence on STAT3 downstream genes 5.00 µM SY5Y Homo sapiens
AZD1480 Western Blot Influence on STAT3 downstream genes 0.50 µM Rh18 Homo sapiens
AZD1480 Western Blot Influence on STAT3 downstream genes 1.00 µM Rh18 Homo sapiens
AZD1480 Western Blot Influence on STAT3 downstream genes 2.50 µM Rh18 Homo sapiens
AZD1480 Western Blot Influence on STAT3 downstream genes 5.00 µM Rh18 Homo sapiens
AZD1480 Western Blot Influence on STAT3 downstream genes 0.50 µM TC32 Homo sapiens
AZD1480 Western Blot Influence on STAT3 downstream genes 1.00 µM TC32 Homo sapiens
AZD1480 Western Blot Influence on STAT3 downstream genes 2.50 µM TC32 Homo sapiens
AZD1480 Western Blot Influence on STAT3 downstream genes 5.00 µM TC32 Homo sapiens
AZD1480 Western Blot Influence on STAT3 downstream genes 0.50 µM KCNR Homo sapiens
AZD1480 Western Blot Influence on STAT3 downstream genes 1.00 µM KCNR Homo sapiens
AZD1480 Western Blot Influence on STAT3 downstream genes 2.50 µM KCNR Homo sapiens
AZD1480 Western Blot Influence on STAT3 downstream genes 5.00 µM KCNR Homo sapiens
AZD1480 Western Blot Influence on STAT3 downstream genes 0.50 µM SY5Y Homo sapiens
AZD1480 Western Blot Influence on STAT3 downstream genes 1.00 µM SY5Y Homo sapiens
AZD1480 Western Blot Influence on STAT3 downstream genes 2.50 µM SY5Y Homo sapiens
AZD1480 Western Blot Influence on STAT3 downstream genes 5.00 µM SY5Y Homo sapiens
AZD1480 Western Blot Influence on STAT3 downstream genes 0.50 µM Rh18 Homo sapiens
AZD1480 Western Blot Influence on STAT3 downstream genes 1.00 µM Rh18 Homo sapiens
AZD1480 Western Blot Influence on STAT3 downstream genes 2.50 µM Rh18 Homo sapiens
AZD1480 Western Blot Influence on STAT3 downstream genes 5.00 µM Rh18 Homo sapiens
AZD1480 Western Blot Influence on STAT3 downstream genes 0.50 µM TC32 Homo sapiens
AZD1480 Western Blot Influence on STAT3 downstream genes 1.00 µM TC32 Homo sapiens
AZD1480 Western Blot Influence on STAT3 downstream genes 2.50 µM TC32 Homo sapiens
AZD1480 Western Blot Influence on STAT3 downstream genes 5.00 µM TC32 Homo sapiens
AZD1480 Western Blot Influence on STAT3 downstream genes 0.50 µM KCNR Homo sapiens
AZD1480 Western Blot Influence on STAT3 downstream genes 1.00 µM KCNR Homo sapiens
AZD1480 Western Blot Influence on STAT3 downstream genes 2.50 µM KCNR Homo sapiens
AZD1480 Western Blot Influence on STAT3 downstream genes 5.00 µM KCNR Homo sapiens
AZD1480 Western Blot Influence on STAT3 downstream genes 0.50 µM SY5Y Homo sapiens
AZD1480 Western Blot Influence on STAT3 downstream genes 1.00 µM SY5Y Homo sapiens
AZD1480 Western Blot Influence on STAT3 downstream genes 2.50 µM SY5Y Homo sapiens
AZD1480 Western Blot Influence on STAT3 downstream genes 5.00 µM SY5Y Homo sapiens
AZD1480 Western Blot Influence on STAT3 downstream genes 0.50 µM Rh18 Homo sapiens
AZD1480 Western Blot Influence on STAT3 downstream genes 1.00 µM Rh18 Homo sapiens
AZD1480 Western Blot Influence on STAT3 downstream genes 2.50 µM Rh18 Homo sapiens
AZD1480 Western Blot Influence on STAT3 downstream genes 5.00 µM Rh18 Homo sapiens
AZD1480 Western Blot Influence on STAT3 downstream genes 0.50 µM TC32 Homo sapiens
AZD1480 Western Blot Influence on STAT3 downstream genes 1.00 µM TC32 Homo sapiens
AZD1480 Western Blot Influence on STAT3 downstream genes 2.50 µM TC32 Homo sapiens
AZD1480 Western Blot Influence on STAT3 downstream genes 5.00 µM TC32 Homo sapiens
AZD1480 Real Time PCR Influence on STAT3 downstream genes 0.50 µM KCNR Homo sapiens
AZD1480 Real Time PCR Influence on STAT3 downstream genes 0.50 µM SY5Y Homo sapiens
AZD1480 Real Time PCR Influence on STAT3 downstream genes 0.50 µM Rh18 Homo sapiens
AZD1480 Real Time PCR Influence on STAT3 downstream genes 0.50 µM TC32 Homo sapiens
AZD1480 Real Time PCR Influence on STAT3 downstream genes 0.50 µM KCNR Homo sapiens
AZD1480 Real Time PCR Influence on STAT3 downstream genes 0.50 µM SY5Y Homo sapiens
AZD1480 Real Time PCR Influence on STAT3 downstream genes 0.50 µM Rh18 Homo sapiens
AZD1480 Real Time PCR Influence on STAT3 downstream genes 0.50 µM TC32 Homo sapiens
AZD1480 Real Time PCR Influence on STAT3 downstream genes 0.50 µM KCNR Homo sapiens
AZD1480 Real Time PCR Influence on STAT3 downstream genes 0.50 µM SY5Y Homo sapiens
AZD1480 Real Time PCR Influence on STAT3 downstream genes 0.50 µM Rh18 Homo sapiens
AZD1480 Real Time PCR Influence on STAT3 downstream genes 0.50 µM TC32 Homo sapiens
AZD1480 Real Time PCR Influence on STAT3 downstream genes 0.50 µM KCNR Homo sapiens
AZD1480 Real Time PCR Influence on STAT3 downstream genes 0.50 µM SY5Y Homo sapiens
AZD1480 Real Time PCR Influence on STAT3 downstream genes 0.50 µM Rh18 Homo sapiens
AZD1480 Real Time PCR Influence on STAT3 downstream genes 0.50 µM TC32 Homo sapiens
AZD1480 Real Time PCR Influence on STAT3 downstream genes 0.50 µM SY5Y Homo sapiens
AZD1480 Real Time PCR Influence on STAT3 downstream genes 0.50 µM Rh18 Homo sapiens
AZD1480 Real Time PCR Influence on STAT3 downstream genes 0.50 µM TC32 Homo sapiens
AZD1480 Real Time PCR Influence on STAT3 downstream genes 0.50 µM KCNR Homo sapiens
AZD1480 Real Time PCR Influence on STAT3 downstream genes 0.50 µM SY5Y Homo sapiens
AZD1480 Real Time PCR Influence on STAT3 downstream genes 0.50 µM Rh18 Homo sapiens
AZD1480 Real Time PCR Influence on STAT3 downstream genes 0.50 µM TC32 Homo sapiens
AZD1480 Real Time PCR Influence on STAT3 downstream genes 0.50 µM KCNR Homo sapiens
AZD1480 Real Time PCR Influence on STAT3 downstream genes 0.50 µM SY5Y Homo sapiens
AZD1480 Real Time PCR Influence on STAT3 downstream genes 0.50 µM Rh18 Homo sapiens
AZD1480 Real Time PCR Influence on STAT3 downstream genes 0.50 µM TC32 Homo sapiens
AZD1480 Tumer volume Influence on tumor growth 30.00 mg/kg KCNR (xenograft) Mus musculus athymic nude mice
AZD1480 Tumer volume Influence on tumor growth 30.00 mg/kg SY5Y (xenograft) Mus musculus athymic nude mice
AZD1480 Tumer volume Influence on tumor growth 30.00 mg/kg Rh18 (xenograft) Mus musculus athymic nude mice
AZD1480 Tumer volume Influence on tumor growth 30.00 mg/kg TC32 (xenograft) Mus musculus athymic nude mice
AZD1480 Western Blot Influence on protein activity in tumor tissue 30.00 mg/kg KCNR (xenograft) Mus musculus athymic nude mice p-STAT3 (Y705)
AZD1480 Western Blot Influence on protein activity in tumor tissue 30.00 mg/kg SY5Y (xenograft) Mus musculus athymic nude mice p-STAT3 (Y705)
AZD1480 Western Blot Influence on protein activity in tumor tissue 30.00 mg/kg Rh18 (xenograft) Mus musculus athymic nude mice p-STAT3 (Y705)
AZD1480 Western Blot Influence on protein activity in tumor tissue 30.00 mg/kg TC32 (xenograft) Mus musculus athymic nude mice p-STAT3 (Y705)
AZD1480 Western Blot Influence on protein activity in tumor tissue 30.00 mg/kg KCNR (xenograft) Mus musculus athymic nude mice STAT3
AZD1480 Western Blot Influence on protein activity in tumor tissue 30.00 mg/kg SY5Y (xenograft) Mus musculus athymic nude mice STAT3
AZD1480 Western Blot Influence on protein activity in tumor tissue 30.00 mg/kg Rh18 (xenograft) Mus musculus athymic nude mice STAT3
AZD1480 Western Blot Influence on protein activity in tumor tissue 30.00 mg/kg TC32 (xenograft) Mus musculus athymic nude mice STAT3
AZD1480 Western Blot Influence on protein activity in tumor tissue 30.00 mg/kg KCNR (xenograft) Mus musculus athymic nude mice
AZD1480 Western Blot Influence on protein activity in tumor tissue 30.00 mg/kg SY5Y (xenograft) Mus musculus athymic nude mice
AZD1480 Western Blot Influence on protein activity in tumor tissue 30.00 mg/kg Rh18 (xenograft) Mus musculus athymic nude mice
AZD1480 Western Blot Influence on protein activity in tumor tissue 30.00 mg/kg TC32 (xenograft) Mus musculus athymic nude mice
AZD1480 Western Blot Influence on protein activity in tumor tissue 30.00 mg/kg KCNR (xenograft) Mus musculus athymic nude mice
AZD1480 Western Blot Influence on protein activity in tumor tissue 30.00 mg/kg SY5Y (xenograft) Mus musculus athymic nude mice
AZD1480 Western Blot Influence on protein activity in tumor tissue 30.00 mg/kg Rh18 (xenograft) Mus musculus athymic nude mice
AZD1480 Western Blot Influence on protein activity in tumor tissue 30.00 mg/kg TC32 (xenograft) Mus musculus athymic nude mice
AZD1480 Western Blot Influence on protein activity in tumor tissue 30.00 mg/kg KCNR (xenograft) Mus musculus athymic nude mice
AZD1480 Western Blot Influence on protein activity in tumor tissue 30.00 mg/kg SY5Y (xenograft) Mus musculus athymic nude mice
AZD1480 Western Blot Influence on protein activity in tumor tissue 30.00 mg/kg Rh18 (xenograft) Mus musculus athymic nude mice
AZD1480 Western Blot Influence on protein activity in tumor tissue 30.00 mg/kg TC32 (xenograft) Mus musculus athymic nude mice
AZD1480 Western Blot Influence on protein activity in tumor tissue 30.00 mg/kg KCNR (xenograft) Mus musculus athymic nude mice
AZD1480 Western Blot Influence on protein activity in tumor tissue 30.00 mg/kg SY5Y (xenograft) Mus musculus athymic nude mice
AZD1480 Western Blot Influence on protein activity in tumor tissue 30.00 mg/kg Rh18 (xenograft) Mus musculus athymic nude mice
AZD1480 Western Blot Influence on protein activity in tumor tissue 30.00 mg/kg TC32 (xenograft) Mus musculus athymic nude mice
AZD1480 Western Blot Influence on protein activity in tumor tissue 30.00 mg/kg KCNR (xenograft) Mus musculus athymic nude mice
AZD1480 Western Blot Influence on protein activity in tumor tissue 30.00 mg/kg SY5Y (xenograft) Mus musculus athymic nude mice
AZD1480 Western Blot Influence on protein activity in tumor tissue 30.00 mg/kg Rh18 (xenograft) Mus musculus athymic nude mice
AZD1480 Western Blot Influence on protein activity in tumor tissue 30.00 mg/kg TC32 (xenograft) Mus musculus athymic nude mice
AZD1480 Western Blot Influence on late protein activity in tumor tissue 30.00 mg/kg KCNR (xenograft) Mus musculus athymic nude mice p-STAT3 (Y705)
AZD1480 Western Blot Influence on late protein activity in tumor tissue 30.00 mg/kg SY5Y (xenograft) Mus musculus athymic nude mice p-STAT3 (Y705)
AZD1480 Western Blot Influence on late protein activity in tumor tissue 30.00 mg/kg Rh18 (xenograft) Mus musculus athymic nude mice p-STAT3 (Y705)
AZD1480 Western Blot Influence on late protein activity in tumor tissue 30.00 mg/kg TC32 (xenograft) Mus musculus athymic nude mice p-STAT3 (Y705)
AZD1480 Western Blot Influence on late protein activity in tumor tissue 30.00 mg/kg KCNR (xenograft) Mus musculus athymic nude mice STAT3
AZD1480 Western Blot Influence on late protein activity in tumor tissue 30.00 mg/kg SY5Y (xenograft) Mus musculus athymic nude mice STAT3
AZD1480 Western Blot Influence on late protein activity in tumor tissue 30.00 mg/kg Rh18 (xenograft) Mus musculus athymic nude mice STAT3
AZD1480 Western Blot Influence on late protein activity in tumor tissue 30.00 mg/kg TC32 (xenograft) Mus musculus athymic nude mice STAT3
AZD1480 Western Blot Influence on late protein activity in tumor tissue 30.00 mg/kg KCNR (xenograft) Mus musculus athymic nude mice
AZD1480 Western Blot Influence on late protein activity in tumor tissue 30.00 mg/kg SY5Y (xenograft) Mus musculus athymic nude mice
AZD1480 Western Blot Influence on late protein activity in tumor tissue 30.00 mg/kg Rh18 (xenograft) Mus musculus athymic nude mice
AZD1480 Western Blot Influence on late protein activity in tumor tissue 30.00 mg/kg TC32 (xenograft) Mus musculus athymic nude mice
AZD1480 Western Blot Influence on late protein activity in tumor tissue 30.00 mg/kg KCNR (xenograft) Mus musculus athymic nude mice
AZD1480 Western Blot Influence on late protein activity in tumor tissue 30.00 mg/kg SY5Y (xenograft) Mus musculus athymic nude mice
AZD1480 Western Blot Influence on late protein activity in tumor tissue 30.00 mg/kg Rh18 (xenograft) Mus musculus athymic nude mice
AZD1480 Western Blot Influence on late protein activity in tumor tissue 30.00 mg/kg TC32 (xenograft) Mus musculus athymic nude mice
AZD1480 Western Blot Influence on late protein activity in tumor tissue 30.00 mg/kg KCNR (xenograft) Mus musculus athymic nude mice
AZD1480 Western Blot Influence on late protein activity in tumor tissue 30.00 mg/kg SY5Y (xenograft) Mus musculus athymic nude mice
AZD1480 Western Blot Influence on late protein activity in tumor tissue 30.00 mg/kg Rh18 (xenograft) Mus musculus athymic nude mice
AZD1480 Western Blot Influence on late protein activity in tumor tissue 30.00 mg/kg TC32 (xenograft) Mus musculus athymic nude mice
AZD1480 Western Blot Influence on late protein activity in tumor tissue 30.00 mg/kg KCNR (xenograft) Mus musculus athymic nude mice
AZD1480 Western Blot Influence on late protein activity in tumor tissue 30.00 mg/kg SY5Y (xenograft) Mus musculus athymic nude mice
AZD1480 Western Blot Influence on late protein activity in tumor tissue 30.00 mg/kg Rh18 (xenograft) Mus musculus athymic nude mice
AZD1480 Western Blot Influence on late protein activity in tumor tissue 30.00 mg/kg TC32 (xenograft) Mus musculus athymic nude mice
AZD1480 Western Blot Influence on late protein activity in tumor tissue 30.00 mg/kg KCNR (xenograft) Mus musculus athymic nude mice
AZD1480 Western Blot Influence on late protein activity in tumor tissue 30.00 mg/kg SY5Y (xenograft) Mus musculus athymic nude mice
AZD1480 Western Blot Influence on late protein activity in tumor tissue 30.00 mg/kg Rh18 (xenograft) Mus musculus athymic nude mice
AZD1480 Western Blot Influence on late protein activity in tumor tissue 30.00 mg/kg TC32 (xenograft) Mus musculus athymic nude mice
AZD1480 Histological staining Influence on tumor growth 30.00 mg/kg KCNR (xenograft) Mus musculus athymic nude mice
AZD1480 Histological staining Influence on tumor growth 30.00 mg/kg SY5Y (xenograft) Mus musculus athymic nude mice
AZD1480 Histological staining Influence on tumor growth 30.00 mg/kg Rh18 (xenograft) Mus musculus athymic nude mice
AZD1480 Histological staining Influence on tumor growth 30.00 mg/kg TC32 (xenograft) Mus musculus athymic nude mice
AZD1480 Flow cytometry- annexin V staining Influence on apoptosis 0.50 µM MO4 Mus musculus
AZD1480 Flow cytometry- annexin V staining Influence on apoptosis 0.50 µM K1735-C4 Mus musculus
AZD1480 Flow cytometry- annexin V staining Influence on apoptosis 0.50 µM 1087-mel Mus musculus
AZD1480 Flow cytometry- annexin V staining Influence on apoptosis 1.00 µM MO4 Mus musculus
AZD1480 Flow cytometry- annexin V staining Influence on apoptosis 1.00 µM K1735-C4 Mus musculus
AZD1480 Flow cytometry- annexin V staining Influence on apoptosis 1.00 µM 1087-mel Mus musculus
AZD1480 Flow cytometry- annexin V staining Influence on apoptosis 5.00 µM MO4 Mus musculus
AZD1480 Flow cytometry- annexin V staining Influence on apoptosis 5.00 µM K1735-C4 Mus musculus
AZD1480 Flow cytometry- annexin V staining Influence on apoptosis 5.00 µM 1087-mel Mus musculus
AZD1480 Flow cytometry- annexin V staining Influence on apoptosis 10.00 µM MO4 Mus musculus
AZD1480 Flow cytometry- annexin V staining Influence on apoptosis 10.00 µM K1735-C4 Mus musculus
AZD1480 Flow cytometry- annexin V staining Influence on apoptosis 10.00 µM 1087-mel Mus musculus
AZD1480 Western Blot Influence on protein activity in presence of IL-6 0.50 µM MO4 Mus musculus p-STAT3
AZD1480 Western Blot Influence on protein activity in presence of IL-6 1.00 µM MO4 Mus musculus p-STAT3
AZD1480 Western Blot Influence on protein activity in presence of IL-6 5.00 µM MO4 Mus musculus p-STAT3
AZD1480 Western Blot Influence on protein activity in presence of IL-6 0.50 µM MO4 Mus musculus
AZD1480 Western Blot Influence on protein activity in presence of IL-6 1.00 µM MO4 Mus musculus
AZD1480 Western Blot Influence on protein activity in presence of IL-6 5.00 µM MO4 Mus musculus
AZD1480 Function of myeloid-derived suppressor cells 30.00 mg/kg MO4 (xenograft) Mus musculus c57BL/6
AZD1480 Flow cytometry Influence on cell proliferation 1.75 µM Splenocytes Mus musculus
AZD1480 Flow cytometry Influence on cell proliferation 1.50 µM Splenocytes Mus musculus
AZD1480 Flow cytometry Influence on cell proliferation 1.25 µM Splenocytes Mus musculus
AZD1480 Flow cytometry Influence on cell proliferation 1.00 µM Splenocytes Mus musculus
AZD1480 Flow cytometry Influence on cell proliferation 0.75 µM Splenocytes Mus musculus
AZD1480 Flow cytometry Influence on cell proliferation 0.50 µM Splenocytes Mus musculus
AZD1480 Flow cytometry Influence on cell proliferation 0.25 µM Splenocytes Mus musculus
AZD1480 Flow cytometry Influence on cell proliferation 0.10 µM Splenocytes Mus musculus
AZD1480 Flow cytometry Influence on cell proliferation 0.05 µM Splenocytes Mus musculus
AZD1480 Flow cytometry Influence on cell proliferation 0.03 µM Splenocytes Mus musculus
AZD1480 Flow cytometry Influence on cell proliferation 0.01 µM Splenocytes Mus musculus
AZD1480 ELISA Influence on cell proliferation 1.50 µM CD 8+ T cells Homo sapiens
AZD1480 ELISA Influence on cell proliferation 1.25 µM CD 8+ T cells Homo sapiens
AZD1480 ELISA Influence on cell proliferation 1.00 µM CD 8+ T cells Homo sapiens
AZD1480 ELISA Influence on cell proliferation 0.75 µM CD 8+ T cells Homo sapiens
AZD1480 ELISA Influence on cell proliferation 0.50 µM CD 8+ T cells Homo sapiens
AZD1480 ELISA Influence on cell proliferation 0.25 µM CD 8+ T cells Homo sapiens
AZD1480 ELISA Influence on cell proliferation 0.10 µM CD 8+ T cells Homo sapiens
AZD1480 ELISA Influence on cell proliferation 0.05 µM CD 8+ T cells Homo sapiens
AZD1480 Western Blot Influence on protein activity 0.10 µM HD-LM2 Homo sapiens p-STAT1
AZD1480 Western Blot Influence on protein activity 0.50 µM HD-LM2 Homo sapiens p-STAT1
AZD1480 Western Blot Influence on protein activity 1.00 µM HD-LM2 Homo sapiens p-STAT1
AZD1480 Western Blot Influence on protein activity 5.00 µM HD-LM2 Homo sapiens p-STAT1
AZD1480 Western Blot Influence on protein activity 0.10 µM HD-LM2 Homo sapiens STAT1
AZD1480 Western Blot Influence on protein activity 0.50 µM HD-LM2 Homo sapiens STAT1
AZD1480 Western Blot Influence on protein activity 1.00 µM HD-LM2 Homo sapiens STAT1
AZD1480 Western Blot Influence on protein activity 5.00 µM HD-LM2 Homo sapiens STAT1
AZD1480 Western Blot Influence on protein activity 0.10 µM L-428 Homo sapiens p-STAT1
AZD1480 Western Blot Influence on protein activity 0.50 µM L-428 Homo sapiens p-STAT1
AZD1480 Western Blot Influence on protein activity 1.00 µM L-428 Homo sapiens p-STAT1
AZD1480 Western Blot Influence on protein activity 5.00 µM L-428 Homo sapiens p-STAT1
AZD1480 Western Blot Influence on protein activity 0.10 µM L-428 Homo sapiens STAT1
AZD1480 Western Blot Influence on protein activity 0.50 µM L-428 Homo sapiens STAT1
AZD1480 Western Blot Influence on protein activity 1.00 µM L-428 Homo sapiens STAT1
AZD1480 Western Blot Influence on protein activity 5.00 µM L-428 Homo sapiens STAT1
AZD1480 Western Blot Influence on protein activity 0.10 µM KM-H2 Homo sapiens p-STAT1
AZD1480 Western Blot Influence on protein activity 0.50 µM KM-H2 Homo sapiens p-STAT1
AZD1480 Western Blot Influence on protein activity 1.00 µM KM-H2 Homo sapiens p-STAT1
AZD1480 Western Blot Influence on protein activity 5.00 µM KM-H2 Homo sapiens p-STAT1
AZD1480 Western Blot Influence on protein activity 0.10 µM KM-H2 Homo sapiens STAT1
AZD1480 Western Blot Influence on protein activity 0.50 µM KM-H2 Homo sapiens STAT1
AZD1480 Western Blot Influence on protein activity 1.00 µM KM-H2 Homo sapiens STAT1
AZD1480 Western Blot Influence on protein activity 5.00 µM KM-H2 Homo sapiens STAT1
AZD1480 Western Blot Influence on protein activity 0.10 µM L-540 Homo sapiens p-STAT1
AZD1480 Western Blot Influence on protein activity 0.50 µM L-540 Homo sapiens p-STAT1
AZD1480 Western Blot Influence on protein activity 1.00 µM L-540 Homo sapiens p-STAT1
AZD1480 Western Blot Influence on protein activity 5.00 µM L-540 Homo sapiens p-STAT1
AZD1480 Western Blot Influence on protein activity 0.10 µM L-540 Homo sapiens STAT1
AZD1480 Western Blot Influence on protein activity 0.50 µM L-540 Homo sapiens STAT1
AZD1480 Western Blot Influence on protein activity 1.00 µM L-540 Homo sapiens STAT1
AZD1480 Western Blot Influence on protein activity 5.00 µM L-540 Homo sapiens STAT1
AZD1480 Western Blot Influence on protein activity 0.10 µM HD-LM2 Homo sapiens p-STAT3
AZD1480 Western Blot Influence on protein activity 0.50 µM HD-LM2 Homo sapiens p-STAT3
AZD1480 Western Blot Influence on protein activity 1.00 µM HD-LM2 Homo sapiens p-STAT3
AZD1480 Western Blot Influence on protein activity 5.00 µM HD-LM2 Homo sapiens p-STAT3
AZD1480 Western Blot Influence on protein activity 0.10 µM HD-LM2 Homo sapiens STAT3
AZD1480 Western Blot Influence on protein activity 0.50 µM HD-LM2 Homo sapiens STAT3
AZD1480 Western Blot Influence on protein activity 1.00 µM HD-LM2 Homo sapiens STAT3
AZD1480 Western Blot Influence on protein activity 5.00 µM HD-LM2 Homo sapiens STAT3
AZD1480 Western Blot Influence on protein activity 0.10 µM L-428 Homo sapiens p-STAT3
AZD1480 Western Blot Influence on protein activity 0.50 µM L-428 Homo sapiens p-STAT3
AZD1480 Western Blot Influence on protein activity 1.00 µM L-428 Homo sapiens p-STAT3
AZD1480 Western Blot Influence on protein activity 5.00 µM L-428 Homo sapiens p-STAT3
AZD1480 Western Blot Influence on protein activity 0.10 µM L-428 Homo sapiens STAT3
AZD1480 Western Blot Influence on protein activity 0.50 µM L-428 Homo sapiens STAT3
AZD1480 Western Blot Influence on protein activity 1.00 µM L-428 Homo sapiens STAT3
AZD1480 Western Blot Influence on protein activity 5.00 µM L-428 Homo sapiens STAT3
AZD1480 Western Blot Influence on protein activity 0.10 µM KM-H2 Homo sapiens p-STAT3
AZD1480 Western Blot Influence on protein activity 0.50 µM KM-H2 Homo sapiens p-STAT3
AZD1480 Western Blot Influence on protein activity 1.00 µM KM-H2 Homo sapiens p-STAT3
AZD1480 Western Blot Influence on protein activity 5.00 µM KM-H2 Homo sapiens p-STAT3
AZD1480 Western Blot Influence on protein activity 0.10 µM KM-H2 Homo sapiens STAT3
AZD1480 Western Blot Influence on protein activity 0.50 µM KM-H2 Homo sapiens STAT3
AZD1480 Western Blot Influence on protein activity 1.00 µM KM-H2 Homo sapiens STAT3
AZD1480 Western Blot Influence on protein activity 5.00 µM KM-H2 Homo sapiens STAT3
AZD1480 Western Blot Influence on protein activity 0.10 µM L-540 Homo sapiens p-STAT3
AZD1480 Western Blot Influence on protein activity 0.50 µM L-540 Homo sapiens p-STAT3
AZD1480 Western Blot Influence on protein activity 1.00 µM L-540 Homo sapiens p-STAT3
AZD1480 Western Blot Influence on protein activity 5.00 µM L-540 Homo sapiens p-STAT3
AZD1480 Western Blot Influence on protein activity 0.10 µM L-540 Homo sapiens STAT3
AZD1480 Western Blot Influence on protein activity 0.50 µM L-540 Homo sapiens STAT3
AZD1480 Western Blot Influence on protein activity 1.00 µM L-540 Homo sapiens STAT3
AZD1480 Western Blot Influence on protein activity 5.00 µM L-540 Homo sapiens STAT3
AZD1480 Western Blot Influence on protein activity 0.10 µM HD-LM2 Homo sapiens p-STAT5
AZD1480 Western Blot Influence on protein activity 0.50 µM HD-LM2 Homo sapiens p-STAT5
AZD1480 Western Blot Influence on protein activity 1.00 µM HD-LM2 Homo sapiens p-STAT5
AZD1480 Western Blot Influence on protein activity 5.00 µM HD-LM2 Homo sapiens p-STAT5
AZD1480 Western Blot Influence on protein activity 0.10 µM HD-LM2 Homo sapiens STAT5
AZD1480 Western Blot Influence on protein activity 0.50 µM HD-LM2 Homo sapiens STAT5
AZD1480 Western Blot Influence on protein activity 1.00 µM HD-LM2 Homo sapiens STAT5
AZD1480 Western Blot Influence on protein activity 5.00 µM HD-LM2 Homo sapiens STAT5
AZD1480 Western Blot Influence on protein activity 0.10 µM L-428 Homo sapiens p-STAT5
AZD1480 Western Blot Influence on protein activity 0.50 µM L-428 Homo sapiens p-STAT5
AZD1480 Western Blot Influence on protein activity 1.00 µM L-428 Homo sapiens p-STAT5
AZD1480 Western Blot Influence on protein activity 5.00 µM L-428 Homo sapiens p-STAT5
AZD1480 Western Blot Influence on protein activity 0.10 µM L-428 Homo sapiens STAT5
AZD1480 Western Blot Influence on protein activity 0.50 µM L-428 Homo sapiens STAT5
AZD1480 Western Blot Influence on protein activity 1.00 µM L-428 Homo sapiens STAT5
AZD1480 Western Blot Influence on protein activity 5.00 µM L-428 Homo sapiens STAT5
AZD1480 Western Blot Influence on protein activity 0.10 µM KM-H2 Homo sapiens p-STAT5
AZD1480 Western Blot Influence on protein activity 0.50 µM KM-H2 Homo sapiens p-STAT5
AZD1480 Western Blot Influence on protein activity 1.00 µM KM-H2 Homo sapiens p-STAT5
AZD1480 Western Blot Influence on protein activity 5.00 µM KM-H2 Homo sapiens p-STAT5
AZD1480 Western Blot Influence on protein activity 0.10 µM KM-H2 Homo sapiens STAT5
AZD1480 Western Blot Influence on protein activity 0.50 µM KM-H2 Homo sapiens STAT5
AZD1480 Western Blot Influence on protein activity 1.00 µM KM-H2 Homo sapiens STAT5
AZD1480 Western Blot Influence on protein activity 5.00 µM KM-H2 Homo sapiens STAT5
AZD1480 Western Blot Influence on protein activity 0.10 µM L-540 Homo sapiens p-STAT5
AZD1480 Western Blot Influence on protein activity 0.50 µM L-540 Homo sapiens p-STAT5
AZD1480 Western Blot Influence on protein activity 1.00 µM L-540 Homo sapiens p-STAT5
AZD1480 Western Blot Influence on protein activity 5.00 µM L-540 Homo sapiens p-STAT5
AZD1480 Western Blot Influence on protein activity 0.10 µM L-540 Homo sapiens STAT5
AZD1480 Western Blot Influence on protein activity 0.50 µM L-540 Homo sapiens STAT5
AZD1480 Western Blot Influence on protein activity 1.00 µM L-540 Homo sapiens STAT5
AZD1480 Western Blot Influence on protein activity 5.00 µM L-540 Homo sapiens STAT5
AZD1480 Western Blot Influence on protein activity 0.10 µM HD-LM2 Homo sapiens p-STAT6
AZD1480 Western Blot Influence on protein activity 0.50 µM HD-LM2 Homo sapiens p-STAT6
AZD1480 Western Blot Influence on protein activity 1.00 µM HD-LM2 Homo sapiens p-STAT6
AZD1480 Western Blot Influence on protein activity 5.00 µM HD-LM2 Homo sapiens p-STAT6
AZD1480 Western Blot Influence on protein activity 0.10 µM HD-LM2 Homo sapiens STAT6
AZD1480 Western Blot Influence on protein activity 0.50 µM HD-LM2 Homo sapiens STAT6
AZD1480 Western Blot Influence on protein activity 1.00 µM HD-LM2 Homo sapiens STAT6
AZD1480 Western Blot Influence on protein activity 5.00 µM HD-LM2 Homo sapiens STAT6
AZD1480 Western Blot Influence on protein activity 0.10 µM L-428 Homo sapiens p-STAT6
AZD1480 Western Blot Influence on protein activity 0.50 µM L-428 Homo sapiens p-STAT6
AZD1480 Western Blot Influence on protein activity 1.00 µM L-428 Homo sapiens p-STAT6
AZD1480 Western Blot Influence on protein activity 5.00 µM L-428 Homo sapiens p-STAT6
AZD1480 Western Blot Influence on protein activity 0.10 µM L-428 Homo sapiens STAT6
AZD1480 Western Blot Influence on protein activity 0.50 µM L-428 Homo sapiens STAT6
AZD1480 Western Blot Influence on protein activity 1.00 µM L-428 Homo sapiens STAT6
AZD1480 Western Blot Influence on protein activity 5.00 µM L-428 Homo sapiens STAT6
AZD1480 Western Blot Influence on protein activity 0.10 µM KM-H2 Homo sapiens p-STAT6
AZD1480 Western Blot Influence on protein activity 0.50 µM KM-H2 Homo sapiens p-STAT6
AZD1480 Western Blot Influence on protein activity 1.00 µM KM-H2 Homo sapiens p-STAT6
AZD1480 Western Blot Influence on protein activity 5.00 µM KM-H2 Homo sapiens p-STAT6
AZD1480 Western Blot Influence on protein activity 0.10 µM KM-H2 Homo sapiens STAT6
AZD1480 Western Blot Influence on protein activity 0.50 µM KM-H2 Homo sapiens STAT6
AZD1480 Western Blot Influence on protein activity 1.00 µM KM-H2 Homo sapiens STAT6
AZD1480 Western Blot Influence on protein activity 5.00 µM KM-H2 Homo sapiens STAT6
AZD1480 Western Blot Influence on protein activity 0.10 µM L-540 Homo sapiens p-STAT6
AZD1480 Western Blot Influence on protein activity 0.50 µM L-540 Homo sapiens p-STAT6
AZD1480 Western Blot Influence on protein activity 1.00 µM L-540 Homo sapiens p-STAT6
AZD1480 Western Blot Influence on protein activity 5.00 µM L-540 Homo sapiens p-STAT6
AZD1480 Western Blot Influence on protein activity 0.10 µM L-540 Homo sapiens STAT6
AZD1480 Western Blot Influence on protein activity 0.50 µM L-540 Homo sapiens STAT6
AZD1480 Western Blot Influence on protein activity 1.00 µM L-540 Homo sapiens STAT6
AZD1480 Western Blot Influence on protein activity 5.00 µM L-540 Homo sapiens STAT6
AZD1480 Western Blot Influence on protein activity 0.10 µM HD-LM2 Homo sapiens
AZD1480 Western Blot Influence on protein activity 0.50 µM HD-LM2 Homo sapiens
AZD1480 Western Blot Influence on protein activity 1.00 µM HD-LM2 Homo sapiens
AZD1480 Western Blot Influence on protein activity 5.00 µM HD-LM2 Homo sapiens
AZD1480 Western Blot Influence on protein activity 0.10 µM L-428 Homo sapiens
AZD1480 Western Blot Influence on protein activity 0.50 µM L-428 Homo sapiens
AZD1480 Western Blot Influence on protein activity 1.00 µM L-428 Homo sapiens
AZD1480 Western Blot Influence on protein activity 5.00 µM L-428 Homo sapiens
AZD1480 Western Blot Influence on protein activity 0.10 µM KM-H2 Homo sapiens
AZD1480 Western Blot Influence on protein activity 0.50 µM KM-H2 Homo sapiens
AZD1480 Western Blot Influence on protein activity 1.00 µM KM-H2 Homo sapiens
AZD1480 Western Blot Influence on protein activity 5.00 µM KM-H2 Homo sapiens
AZD1480 Western Blot Influence on protein activity 0.10 µM L-540 Homo sapiens
AZD1480 Western Blot Influence on protein activity 0.50 µM L-540 Homo sapiens
AZD1480 Western Blot Influence on protein activity 1.00 µM L-540 Homo sapiens
AZD1480 Western Blot Influence on protein activity 5.00 µM L-540 Homo sapiens
AZD1480 MTS Influence on apoptosis 1.00 µM HD-LM2 Homo sapiens
AZD1480 MTS Influence on apoptosis 1.00 µM L-428 Homo sapiens
AZD1480 MTS Influence on apoptosis 1.00 µM KM-H2 Homo sapiens
AZD1480 MTS Influence on apoptosis 1.00 µM L-540 Homo sapiens
AZD1480 MTS Influence on apoptosis 5.00 µM HD-LM2 Homo sapiens
AZD1480 MTS Influence on apoptosis 5.00 µM L-428 Homo sapiens
AZD1480 MTS Influence on apoptosis 5.00 µM KM-H2 Homo sapiens
AZD1480 MTS Influence on apoptosis 5.00 µM L-540 Homo sapiens
AZD1480 Flow cytometry- annexin V staining Influence on apoptosis 1.00 µM HD-LM2 Homo sapiens
AZD1480 Flow cytometry- annexin V staining Influence on apoptosis 5.00 µM HD-LM2 Homo sapiens
AZD1480 Flow cytometry- annexin V staining Influence on apoptosis 1.00 µM L-428 Homo sapiens
AZD1480 Flow cytometry- annexin V staining Influence on apoptosis 5.00 µM L-428 Homo sapiens
AZD1480 Flow cytometry- annexin V staining Influence on apoptosis 1.00 µM KM-H2 Homo sapiens
AZD1480 Flow cytometry- annexin V staining Influence on apoptosis 5.00 µM KM-H2 Homo sapiens
AZD1480 Flow cytometry- annexin V staining Influence on apoptosis 1.00 µM L-540 Homo sapiens
AZD1480 Flow cytometry- annexin V staining Influence on apoptosis 5.00 µM L-540 Homo sapiens
AZD1480 Western Blot Influence on apoptosis 1.00 µM HD-LM2 Homo sapiens
AZD1480 Western Blot Influence on apoptosis 5.00 µM HD-LM2 Homo sapiens
AZD1480 Western Blot Influence on apoptosis 1.00 µM HD-LM2 Homo sapiens
AZD1480 Western Blot Influence on apoptosis 5.00 µM HD-LM2 Homo sapiens
AZD1480 Western Blot Influence on apoptosis 1.00 µM HD-LM2 Homo sapiens
AZD1480 Western Blot Influence on apoptosis 5.00 µM HD-LM2 Homo sapiens
AZD1480 Western Blot Influence on apoptosis 1.00 µM HD-LM2 Homo sapiens
AZD1480 Western Blot Influence on apoptosis 5.00 µM HD-LM2 Homo sapiens
AZD1480 Western Blot Influence on apoptosis 1.00 µM L-428 Homo sapiens
AZD1480 Western Blot Influence on apoptosis 5.00 µM L-428 Homo sapiens
AZD1480 Western Blot Influence on apoptosis 1.00 µM L-428 Homo sapiens
AZD1480 Western Blot Influence on apoptosis 5.00 µM L-428 Homo sapiens
AZD1480 Western Blot Influence on apoptosis 1.00 µM L-428 Homo sapiens
AZD1480 Western Blot Influence on apoptosis 5.00 µM L-428 Homo sapiens
AZD1480 Western Blot Influence on apoptosis 1.00 µM L-428 Homo sapiens
AZD1480 Western Blot Influence on apoptosis 5.00 µM L-428 Homo sapiens
AZD1480 Western Blot Influence on apoptosis 1.00 µM KM-H2 Homo sapiens
AZD1480 Western Blot Influence on apoptosis 5.00 µM KM-H2 Homo sapiens
AZD1480 Western Blot Influence on apoptosis 1.00 µM KM-H2 Homo sapiens
AZD1480 Western Blot Influence on apoptosis 5.00 µM KM-H2 Homo sapiens
AZD1480 Western Blot Influence on apoptosis 1.00 µM KM-H2 Homo sapiens
AZD1480 Western Blot Influence on apoptosis 5.00 µM KM-H2 Homo sapiens
AZD1480 Western Blot Influence on apoptosis 1.00 µM KM-H2 Homo sapiens
AZD1480 Western Blot Influence on apoptosis 5.00 µM KM-H2 Homo sapiens
AZD1480 Western Blot Influence on apoptosis 1.00 µM L-540 Homo sapiens
AZD1480 Western Blot Influence on apoptosis 5.00 µM L-540 Homo sapiens
AZD1480 Western Blot Influence on apoptosis 1.00 µM L-540 Homo sapiens
AZD1480 Western Blot Influence on apoptosis 5.00 µM L-540 Homo sapiens
AZD1480 Western Blot Influence on apoptosis 1.00 µM L-540 Homo sapiens
AZD1480 Western Blot Influence on apoptosis 5.00 µM L-540 Homo sapiens
AZD1480 Western Blot Influence on apoptosis 1.00 µM L-540 Homo sapiens
AZD1480 Western Blot Influence on apoptosis 5.00 µM L-540 Homo sapiens
AZD1480 Western Blot Influence on protein activity 0.10 µM HD-LM2 Homo sapiens
AZD1480 Western Blot Influence on protein activity 0.50 µM HD-LM2 Homo sapiens
AZD1480 Western Blot Influence on protein activity 1.00 µM HD-LM2 Homo sapiens
AZD1480 Western Blot Influence on protein activity 5.00 µM HD-LM2 Homo sapiens
AZD1480 Western Blot Influence on protein activity 0.10 µM HD-LM2 Homo sapiens
AZD1480 Western Blot Influence on protein activity 0.50 µM HD-LM2 Homo sapiens
AZD1480 Western Blot Influence on protein activity 1.00 µM HD-LM2 Homo sapiens
AZD1480 Western Blot Influence on protein activity 5.00 µM HD-LM2 Homo sapiens
AZD1480 Western Blot Influence on protein activity 0.10 µM HD-LM2 Homo sapiens
AZD1480 Western Blot Influence on protein activity 0.50 µM HD-LM2 Homo sapiens
AZD1480 Western Blot Influence on protein activity 1.00 µM HD-LM2 Homo sapiens
AZD1480 Western Blot Influence on protein activity 5.00 µM HD-LM2 Homo sapiens
AZD1480 Western Blot Influence on protein activity 0.10 µM HD-LM2 Homo sapiens
AZD1480 Western Blot Influence on protein activity 0.50 µM HD-LM2 Homo sapiens
AZD1480 Western Blot Influence on protein activity 1.00 µM HD-LM2 Homo sapiens
AZD1480 Western Blot Influence on protein activity 5.00 µM HD-LM2 Homo sapiens
AZD1480 Western Blot Influence on protein activity 0.10 µM HD-LM2 Homo sapiens
AZD1480 Western Blot Influence on protein activity 0.50 µM HD-LM2 Homo sapiens
AZD1480 Western Blot Influence on protein activity 1.00 µM HD-LM2 Homo sapiens
AZD1480 Western Blot Influence on protein activity 5.00 µM HD-LM2 Homo sapiens
AZD1480 Western Blot Influence on protein activity 0.10 µM HD-LM2 Homo sapiens
AZD1480 Western Blot Influence on protein activity 0.50 µM HD-LM2 Homo sapiens
AZD1480 Western Blot Influence on protein activity 1.00 µM HD-LM2 Homo sapiens
AZD1480 Western Blot Influence on protein activity 5.00 µM HD-LM2 Homo sapiens
AZD1480 Western Blot Influence on protein activity 0.10 µM HD-LM2 Homo sapiens
AZD1480 Western Blot Influence on protein activity 0.50 µM HD-LM2 Homo sapiens
AZD1480 Western Blot Influence on protein activity 1.00 µM HD-LM2 Homo sapiens
AZD1480 Western Blot Influence on protein activity 5.00 µM HD-LM2 Homo sapiens
AZD1480 Western Blot Influence on protein activity 0.10 µM HD-LM2 Homo sapiens
AZD1480 Western Blot Influence on protein activity 0.50 µM HD-LM2 Homo sapiens
AZD1480 Western Blot Influence on protein activity 1.00 µM HD-LM2 Homo sapiens
AZD1480 Western Blot Influence on protein activity 5.00 µM HD-LM2 Homo sapiens
AZD1480 Western Blot Influence on protein activity 0.10 µM HD-LM2 Homo sapiens
AZD1480 Western Blot Influence on protein activity 0.50 µM HD-LM2 Homo sapiens
AZD1480 Western Blot Influence on protein activity 1.00 µM HD-LM2 Homo sapiens
AZD1480 Western Blot Influence on protein activity 5.00 µM HD-LM2 Homo sapiens
AZD1480 Western Blot Influence on protein activity 0.10 µM L-428 Homo sapiens
AZD1480 Western Blot Influence on protein activity 0.50 µM L-428 Homo sapiens
AZD1480 Western Blot Influence on protein activity 1.00 µM L-428 Homo sapiens
AZD1480 Western Blot Influence on protein activity 5.00 µM L-428 Homo sapiens
AZD1480 Western Blot Influence on protein activity 0.10 µM L-428 Homo sapiens
AZD1480 Western Blot Influence on protein activity 0.50 µM L-428 Homo sapiens
AZD1480 Western Blot Influence on protein activity 1.00 µM L-428 Homo sapiens
AZD1480 Western Blot Influence on protein activity 5.00 µM L-428 Homo sapiens
AZD1480 Western Blot Influence on protein activity 0.10 µM L-428 Homo sapiens
AZD1480 Western Blot Influence on protein activity 0.50 µM L-428 Homo sapiens
AZD1480 Western Blot Influence on protein activity 1.00 µM L-428 Homo sapiens
AZD1480 Western Blot Influence on protein activity 5.00 µM L-428 Homo sapiens
AZD1480 Western Blot Influence on protein activity 0.10 µM L-428 Homo sapiens
AZD1480 Western Blot Influence on protein activity 0.50 µM L-428 Homo sapiens
AZD1480 Western Blot Influence on protein activity 1.00 µM L-428 Homo sapiens
AZD1480 Western Blot Influence on protein activity 5.00 µM L-428 Homo sapiens
AZD1480 Western Blot Influence on protein activity 0.10 µM L-428 Homo sapiens
AZD1480 Western Blot Influence on protein activity 0.50 µM L-428 Homo sapiens
AZD1480 Western Blot Influence on protein activity 1.00 µM L-428 Homo sapiens
AZD1480 Western Blot Influence on protein activity 5.00 µM L-428 Homo sapiens
AZD1480 Western Blot Influence on protein activity 0.10 µM L-428 Homo sapiens
AZD1480 Western Blot Influence on protein activity 0.50 µM L-428 Homo sapiens
AZD1480 Western Blot Influence on protein activity 1.00 µM L-428 Homo sapiens
AZD1480 Western Blot Influence on protein activity 5.00 µM L-428 Homo sapiens
AZD1480 Western Blot Influence on protein activity 0.10 µM L-428 Homo sapiens
AZD1480 Western Blot Influence on protein activity 0.50 µM L-428 Homo sapiens
AZD1480 Western Blot Influence on protein activity 1.00 µM L-428 Homo sapiens
AZD1480 Western Blot Influence on protein activity 5.00 µM L-428 Homo sapiens
AZD1480 Western Blot Influence on protein activity 0.10 µM L-428 Homo sapiens
AZD1480 Western Blot Influence on protein activity 0.50 µM L-428 Homo sapiens
AZD1480 Western Blot Influence on protein activity 1.00 µM L-428 Homo sapiens
AZD1480 Western Blot Influence on protein activity 5.00 µM L-428 Homo sapiens
AZD1480 Western Blot Influence on protein activity 0.10 µM L-428 Homo sapiens
AZD1480 Western Blot Influence on protein activity 0.50 µM L-428 Homo sapiens
AZD1480 Western Blot Influence on protein activity 1.00 µM L-428 Homo sapiens
AZD1480 Western Blot Influence on protein activity 5.00 µM L-428 Homo sapiens
AZD1480 Western Blot Influence on protein activity 0.10 µM L-540 Homo sapiens
AZD1480 Western Blot Influence on protein activity 0.50 µM L-540 Homo sapiens
AZD1480 Western Blot Influence on protein activity 1.00 µM L-540 Homo sapiens
AZD1480 Western Blot Influence on protein activity 5.00 µM L-540 Homo sapiens
AZD1480 Western Blot Influence on protein activity 0.10 µM L-540 Homo sapiens
AZD1480 Western Blot Influence on protein activity 0.50 µM L-540 Homo sapiens
AZD1480 Western Blot Influence on protein activity 1.00 µM L-540 Homo sapiens
AZD1480 Western Blot Influence on protein activity 5.00 µM L-540 Homo sapiens
AZD1480 Western Blot Influence on protein activity 0.10 µM L-540 Homo sapiens
AZD1480 Western Blot Influence on protein activity 0.50 µM L-540 Homo sapiens
AZD1480 Western Blot Influence on protein activity 1.00 µM L-540 Homo sapiens
AZD1480 Western Blot Influence on protein activity 5.00 µM L-540 Homo sapiens
AZD1480 Western Blot Influence on protein activity 0.10 µM L-540 Homo sapiens
AZD1480 Western Blot Influence on protein activity 0.50 µM L-540 Homo sapiens
AZD1480 Western Blot Influence on protein activity 1.00 µM L-540 Homo sapiens
AZD1480 Western Blot Influence on protein activity 5.00 µM L-540 Homo sapiens
AZD1480 Western Blot Influence on protein activity 0.10 µM L-540 Homo sapiens
AZD1480 Western Blot Influence on protein activity 0.50 µM L-540 Homo sapiens
AZD1480 Western Blot Influence on protein activity 1.00 µM L-540 Homo sapiens
AZD1480 Western Blot Influence on protein activity 5.00 µM L-540 Homo sapiens
AZD1480 Western Blot Influence on protein activity 0.10 µM L-540 Homo sapiens
AZD1480 Western Blot Influence on protein activity 0.50 µM L-540 Homo sapiens
AZD1480 Western Blot Influence on protein activity 1.00 µM L-540 Homo sapiens
AZD1480 Western Blot Influence on protein activity 5.00 µM L-540 Homo sapiens
AZD1480 Western Blot Influence on protein activity 0.10 µM L-540 Homo sapiens
AZD1480 Western Blot Influence on protein activity 0.50 µM L-540 Homo sapiens
AZD1480 Western Blot Influence on protein activity 1.00 µM L-540 Homo sapiens
AZD1480 Western Blot Influence on protein activity 5.00 µM L-540 Homo sapiens
AZD1480 Western Blot Influence on protein activity 0.10 µM L-540 Homo sapiens
AZD1480 Western Blot Influence on protein activity 0.50 µM L-540 Homo sapiens
AZD1480 Western Blot Influence on protein activity 1.00 µM L-540 Homo sapiens
AZD1480 Western Blot Influence on protein activity 5.00 µM L-540 Homo sapiens
AZD1480 Western Blot Influence on protein activity 0.10 µM L-540 Homo sapiens
AZD1480 Western Blot Influence on protein activity 0.50 µM L-540 Homo sapiens
AZD1480 Western Blot Influence on protein activity 1.00 µM L-540 Homo sapiens
AZD1480 Western Blot Influence on protein activity 5.00 µM L-540 Homo sapiens
AZD1480 Western Blot Influence on protein activity 0.10 µM HD-LM2 Homo sapiens
AZD1480 Western Blot Influence on protein activity 0.50 µM HD-LM2 Homo sapiens
AZD1480 Western Blot Influence on protein activity 1.00 µM HD-LM2 Homo sapiens
AZD1480 Western Blot Influence on protein activity 5.00 µM HD-LM2 Homo sapiens
AZD1480 Western Blot Influence on protein activity 0.10 µM HD-LM2 Homo sapiens
AZD1480 Western Blot Influence on protein activity 0.50 µM HD-LM2 Homo sapiens
AZD1480 Western Blot Influence on protein activity 1.00 µM HD-LM2 Homo sapiens
AZD1480 Western Blot Influence on protein activity 5.00 µM HD-LM2 Homo sapiens
AZD1480 Western Blot Influence on protein activity 0.10 µM HD-LM2 Homo sapiens
AZD1480 Western Blot Influence on protein activity 0.50 µM HD-LM2 Homo sapiens
AZD1480 Western Blot Influence on protein activity 1.00 µM HD-LM2 Homo sapiens
AZD1480 Western Blot Influence on protein activity 5.00 µM HD-LM2 Homo sapiens
AZD1480 Western Blot Influence on protein activity 0.10 µM HD-LM2 Homo sapiens
AZD1480 Western Blot Influence on protein activity 0.50 µM HD-LM2 Homo sapiens
AZD1480 Western Blot Influence on protein activity 1.00 µM HD-LM2 Homo sapiens
AZD1480 Western Blot Influence on protein activity 5.00 µM HD-LM2 Homo sapiens
AZD1480 Western Blot Influence on protein activity 0.10 µM HD-LM2 Homo sapiens
AZD1480 Western Blot Influence on protein activity 0.50 µM HD-LM2 Homo sapiens
AZD1480 Western Blot Influence on protein activity 1.00 µM HD-LM2 Homo sapiens
AZD1480 Western Blot Influence on protein activity 5.00 µM HD-LM2 Homo sapiens
AZD1480 Western Blot Influence on protein activity 0.10 µM HD-LM2 Homo sapiens
AZD1480 Western Blot Influence on protein activity 0.50 µM HD-LM2 Homo sapiens
AZD1480 Western Blot Influence on protein activity 1.00 µM HD-LM2 Homo sapiens
AZD1480 Western Blot Influence on protein activity 5.00 µM HD-LM2 Homo sapiens
AZD1480 Western Blot Influence on protein activity 0.10 µM HD-LM2 Homo sapiens
AZD1480 Western Blot Influence on protein activity 0.50 µM HD-LM2 Homo sapiens
AZD1480 Western Blot Influence on protein activity 1.00 µM HD-LM2 Homo sapiens
AZD1480 Western Blot Influence on protein activity 5.00 µM HD-LM2 Homo sapiens
AZD1480 Western Blot Influence on protein activity 0.10 µM L-428 Homo sapiens
AZD1480 Western Blot Influence on protein activity 0.50 µM L-428 Homo sapiens
AZD1480 Western Blot Influence on protein activity 1.00 µM L-428 Homo sapiens
AZD1480 Western Blot Influence on protein activity 5.00 µM L-428 Homo sapiens
AZD1480 Western Blot Influence on protein activity 0.10 µM L-428 Homo sapiens
AZD1480 Western Blot Influence on protein activity 0.50 µM L-428 Homo sapiens
AZD1480 Western Blot Influence on protein activity 1.00 µM L-428 Homo sapiens
AZD1480 Western Blot Influence on protein activity 5.00 µM L-428 Homo sapiens
AZD1480 Western Blot Influence on protein activity 0.10 µM L-428 Homo sapiens
AZD1480 Western Blot Influence on protein activity 0.50 µM L-428 Homo sapiens
AZD1480 Western Blot Influence on protein activity 1.00 µM L-428 Homo sapiens
AZD1480 Western Blot Influence on protein activity 5.00 µM L-428 Homo sapiens
AZD1480 Western Blot Influence on protein activity 0.10 µM L-428 Homo sapiens
AZD1480 Western Blot Influence on protein activity 0.50 µM L-428 Homo sapiens
AZD1480 Western Blot Influence on protein activity 1.00 µM L-428 Homo sapiens
AZD1480 Western Blot Influence on protein activity 5.00 µM L-428 Homo sapiens
AZD1480 Western Blot Influence on protein activity 0.10 µM L-428 Homo sapiens
AZD1480 Western Blot Influence on protein activity 0.50 µM L-428 Homo sapiens
AZD1480 Western Blot Influence on protein activity 1.00 µM L-428 Homo sapiens
AZD1480 Western Blot Influence on protein activity 5.00 µM L-428 Homo sapiens
AZD1480 Western Blot Influence on protein activity 0.10 µM L-428 Homo sapiens
AZD1480 Western Blot Influence on protein activity 0.50 µM L-428 Homo sapiens
AZD1480 Western Blot Influence on protein activity 1.00 µM L-428 Homo sapiens
AZD1480 Western Blot Influence on protein activity 5.00 µM L-428 Homo sapiens
AZD1480 Western Blot Influence on protein activity 0.10 µM L-428 Homo sapiens
AZD1480 Western Blot Influence on protein activity 0.50 µM L-428 Homo sapiens
AZD1480 Western Blot Influence on protein activity 1.00 µM L-428 Homo sapiens
AZD1480 Western Blot Influence on protein activity 5.00 µM L-428 Homo sapiens
AZD1480 Western Blot Influence on protein activity 0.10 µM L-540 Homo sapiens
AZD1480 Western Blot Influence on protein activity 0.50 µM L-540 Homo sapiens
AZD1480 Western Blot Influence on protein activity 1.00 µM L-540 Homo sapiens
AZD1480 Western Blot Influence on protein activity 5.00 µM L-540 Homo sapiens
AZD1480 Western Blot Influence on protein activity 0.10 µM L-540 Homo sapiens
AZD1480 Western Blot Influence on protein activity 0.50 µM L-540 Homo sapiens
AZD1480 Western Blot Influence on protein activity 1.00 µM L-540 Homo sapiens
AZD1480 Western Blot Influence on protein activity 5.00 µM L-540 Homo sapiens
AZD1480 Western Blot Influence on protein activity 0.10 µM L-540 Homo sapiens
AZD1480 Western Blot Influence on protein activity 0.50 µM L-540 Homo sapiens
AZD1480 Western Blot Influence on protein activity 1.00 µM L-540 Homo sapiens
AZD1480 Western Blot Influence on protein activity 5.00 µM L-540 Homo sapiens
AZD1480 Western Blot Influence on protein activity 0.10 µM L-540 Homo sapiens
AZD1480 Western Blot Influence on protein activity 0.50 µM L-540 Homo sapiens
AZD1480 Western Blot Influence on protein activity 1.00 µM L-540 Homo sapiens
AZD1480 Western Blot Influence on protein activity 5.00 µM L-540 Homo sapiens
AZD1480 Western Blot Influence on protein activity 0.10 µM L-540 Homo sapiens
AZD1480 Western Blot Influence on protein activity 0.50 µM L-540 Homo sapiens
AZD1480 Western Blot Influence on protein activity 1.00 µM L-540 Homo sapiens
AZD1480 Western Blot Influence on protein activity 5.00 µM L-540 Homo sapiens
AZD1480 Western Blot Influence on protein activity 0.10 µM L-540 Homo sapiens
AZD1480 Western Blot Influence on protein activity 0.50 µM L-540 Homo sapiens
AZD1480 Western Blot Influence on protein activity 1.00 µM L-540 Homo sapiens
AZD1480 Western Blot Influence on protein activity 5.00 µM L-540 Homo sapiens
AZD1480 Western Blot Influence on protein activity 0.10 µM L-540 Homo sapiens
AZD1480 Western Blot Influence on protein activity 0.50 µM L-540 Homo sapiens
AZD1480 Western Blot Influence on protein activity 1.00 µM L-540 Homo sapiens
AZD1480 Western Blot Influence on protein activity 5.00 µM L-540 Homo sapiens
AZD1480 Flow cytometry Influence on immunoregulation 1.00 µM HD-LM2 Homo sapiens
AZD1480 Flow cytometry Influence on immunoregulation 1.00 µM L-428 Homo sapiens
AZD1480 Flow cytometry Influence on immunoregulation 1.00 µM KM-H2 Homo sapiens
AZD1480 Flow cytometry Influence on immunoregulation 1.00 µM L-540 Homo sapiens
AZD1480 Flow cytometry Influence on immunoregulation 1.00 µM HD-LM2 Homo sapiens
AZD1480 Flow cytometry Influence on immunoregulation 1.00 µM L-428 Homo sapiens
AZD1480 Flow cytometry Influence on immunoregulation 1.00 µM KM-H2 Homo sapiens
AZD1480 Flow cytometry Influence on immunoregulation 1.00 µM L-540 Homo sapiens
AZD1480 ELISA Influence on cytokine secretion 1.00 µM HD-LM2 Homo sapiens
AZD1480 ELISA Influence on cytokine secretion 1.00 µM L-428 Homo sapiens
AZD1480 ELISA Influence on cytokine secretion 1.00 µM L-540 Homo sapiens
AZD1480 ELISA Influence on cytokine secretion 1.00 µM HD-LM2 Homo sapiens
AZD1480 ELISA Influence on cytokine secretion 1.00 µM L-428 Homo sapiens
AZD1480 ELISA Influence on cytokine secretion 1.00 µM L-540 Homo sapiens
AZD1480 ELISA Influence on cytokine secretion 1.00 µM HD-LM2 Homo sapiens
AZD1480 ELISA Influence on cytokine secretion 1.00 µM L-428 Homo sapiens
AZD1480 ELISA Influence on cytokine secretion 1.00 µM L-540 Homo sapiens
AZD1480 Flow cytometry Influence on cell cycle 1.00 µM HD-LM2 Homo sapiens
AZD1480 Flow cytometry Influence on cell cycle 5.00 µM HD-LM2 Homo sapiens
AZD1480 Flow cytometry Influence on cell cycle 1.00 µM L-428 Homo sapiens
AZD1480 Flow cytometry Influence on cell cycle 5.00 µM L-428 Homo sapiens
AZD1480 Flow cytometry Influence on cell cycle 1.00 µM KM-H2 Homo sapiens
AZD1480 Flow cytometry Influence on cell cycle 5.00 µM KM-H2 Homo sapiens
AZD1480 Flow cytometry Influence on cell cycle 1.00 µM L-540 Homo sapiens
AZD1480 Flow cytometry Influence on cell cycle 5.00 µM L-540 Homo sapiens
AZD1480 Western Blot Influence on cell cycle 1.00 µM HD-LM2 Homo sapiens
AZD1480 Western Blot Influence on cell cycle 5.00 µM HD-LM2 Homo sapiens
AZD1480 Western Blot Influence on cell cycle 1.00 µM L-428 Homo sapiens
AZD1480 Western Blot Influence on cell cycle 5.00 µM L-428 Homo sapiens
AZD1480 Western Blot Influence on cell cycle 1.00 µM KM-H2 Homo sapiens
AZD1480 Western Blot Influence on cell cycle 5.00 µM KM-H2 Homo sapiens
AZD1480 Western Blot Influence on cell cycle 1.00 µM L-540 Homo sapiens
AZD1480 Western Blot Influence on cell cycle 5.00 µM L-540 Homo sapiens
AZD1480 Western Blot Influence on cell cycle 1.00 µM HD-LM2 Homo sapiens
AZD1480 Western Blot Influence on cell cycle 5.00 µM HD-LM2 Homo sapiens
AZD1480 Western Blot Influence on cell cycle 1.00 µM L-428 Homo sapiens
AZD1480 Western Blot Influence on cell cycle 5.00 µM L-428 Homo sapiens
AZD1480 Western Blot Influence on cell cycle 1.00 µM KM-H2 Homo sapiens
AZD1480 Western Blot Influence on cell cycle 5.00 µM KM-H2 Homo sapiens
AZD1480 Western Blot Influence on cell cycle 1.00 µM L-540 Homo sapiens
AZD1480 Western Blot Influence on cell cycle 5.00 µM L-540 Homo sapiens
AZD1480 Western Blot Influence on cell cycle 1.00 µM HD-LM2 Homo sapiens
AZD1480 Western Blot Influence on cell cycle 5.00 µM HD-LM2 Homo sapiens
AZD1480 Western Blot Influence on cell cycle 1.00 µM L-428 Homo sapiens
AZD1480 Western Blot Influence on cell cycle 5.00 µM L-428 Homo sapiens
AZD1480 Western Blot Influence on cell cycle 1.00 µM KM-H2 Homo sapiens
AZD1480 Western Blot Influence on cell cycle 5.00 µM KM-H2 Homo sapiens
AZD1480 Western Blot Influence on cell cycle 1.00 µM L-540 Homo sapiens
AZD1480 Western Blot Influence on cell cycle 5.00 µM L-540 Homo sapiens
AZD1480 Western Blot Influence on cell cycle 1.00 µM HD-LM2 Homo sapiens
AZD1480 Western Blot Influence on cell cycle 5.00 µM HD-LM2 Homo sapiens
AZD1480 Western Blot Influence on cell cycle 1.00 µM L-428 Homo sapiens
AZD1480 Western Blot Influence on cell cycle 5.00 µM L-428 Homo sapiens
AZD1480 Western Blot Influence on cell cycle 1.00 µM KM-H2 Homo sapiens
AZD1480 Western Blot Influence on cell cycle 5.00 µM KM-H2 Homo sapiens
AZD1480 Western Blot Influence on cell cycle 1.00 µM L-540 Homo sapiens
AZD1480 Western Blot Influence on cell cycle 5.00 µM L-540 Homo sapiens
AZD1480 Western Blot Influence on cell cycle 1.00 µM HD-LM2 Homo sapiens
AZD1480 Western Blot Influence on cell cycle 5.00 µM HD-LM2 Homo sapiens
AZD1480 Western Blot Influence on cell cycle 1.00 µM L-428 Homo sapiens
AZD1480 Western Blot Influence on cell cycle 5.00 µM L-428 Homo sapiens
AZD1480 Western Blot Influence on cell cycle 1.00 µM KM-H2 Homo sapiens
AZD1480 Western Blot Influence on cell cycle 5.00 µM KM-H2 Homo sapiens
AZD1480 Western Blot Influence on cell cycle 1.00 µM L-540 Homo sapiens
AZD1480 Western Blot Influence on cell cycle 5.00 µM L-540 Homo sapiens
AZD1480 Trypan blue exclusion assay Influence on cell proliferation 1.00 µM CLBL-1 Canis lupus familiaris
AZD1480 Trypan blue exclusion assay Influence on cell proliferation 2.00 µM CLBL-1 Canis lupus familiaris
AZD1480 Trypan blue exclusion assay Influence on cell proliferation 3.00 µM CLBL-1 Canis lupus familiaris
AZD1480 Trypan blue exclusion assay Influence on cell proliferation 4.00 µM CLBL-1 Canis lupus familiaris
AZD1480 Trypan blue exclusion assay Influence on cell proliferation 5.00 µM CLBL-1 Canis lupus familiaris
AZD1480 MTS Assay Influence on cell proliferation 1.00 µM CLBL-1 Canis lupus familiaris
AZD1480 MTS Assay Influence on cell proliferation 2.00 µM CLBL-1 Canis lupus familiaris
AZD1480 MTS Assay Influence on cell proliferation 5.00 µM CLBL-1 Canis lupus familiaris
AZD1480 MTS Assay Influence on cell proliferation 1.00 µM CLBL-1 Canis lupus familiaris patient 1
AZD1480 MTS Assay Influence on cell proliferation 2.00 µM CLBL-1 Canis lupus familiaris patient 1
AZD1480 MTS Assay Influence on cell proliferation 5.00 µM CLBL-1 Canis lupus familiaris patient 1
AZD1480 MTS Assay Influence on cell proliferation 1.00 µM CLBL-1 Canis lupus familiaris patient 2
AZD1480 MTS Assay Influence on cell proliferation 2.00 µM CLBL-1 Canis lupus familiaris patient 2
AZD1480 MTS Assay Influence on cell proliferation 5.00 µM CLBL-1 Canis lupus familiaris patient 2
AZD1480 MTS Assay Influence on cell proliferation 1.00 µM CLBL-1 Canis lupus familiaris patient 3
AZD1480 MTS Assay Influence on cell proliferation 2.00 µM CLBL-1 Canis lupus familiaris patient 3
AZD1480 MTS Assay Influence on cell proliferation 5.00 µM CLBL-1 Canis lupus familiaris patient 3
AZD1480 MTS Assay Influence on cell proliferation 1.00 µM OCL-LY7 Homo sapiens
AZD1480 MTS Assay Influence on cell proliferation 2.00 µM OCL-LY7 Homo sapiens
AZD1480 MTS Assay Influence on cell proliferation 5.00 µM OCL-LY7 Homo sapiens
AZD1480 Real Time PCR Influence on gene expression 5.00 µM CLBL-1 Canis lupus familiaris
AZD1480 Real Time PCR Influence on gene expression 5.00 µM CLBL-1 Canis lupus familiaris
AZD1480 Western Blot Influence on protein activity 1.00 µM CLBL-1 Canis lupus familiaris
AZD1480 Western Blot Influence on protein activity 2.00 µM CLBL-1 Canis lupus familiaris
AZD1480 Western Blot Influence on protein activity 5.00 µM CLBL-1 Canis lupus familiaris
AZD1480 Western Blot Influence on protein activity 1.00 µM CLBL-1 Canis lupus familiaris p-STAT3
AZD1480 Western Blot Influence on protein activity 2.00 µM CLBL-1 Canis lupus familiaris p-STAT3
AZD1480 Western Blot Influence on protein activity 5.00 µM CLBL-1 Canis lupus familiaris p-STAT3
AZD1480 Western Blot Influence on protein activity 1.00 µM CLBL-1 Canis lupus familiaris
AZD1480 Western Blot Influence on protein activity 2.00 µM CLBL-1 Canis lupus familiaris
AZD1480 Western Blot Influence on protein activity 5.00 µM CLBL-1 Canis lupus familiaris
AZD1480 Flow cytometry Influence on protein activity in presence of IL-6 5.00 µM CLBL-1 Canis lupus familiaris p-STAT3
AZD1480 Flow cytometr- annexin V staining Influence on cell apoptosis 2.00 µM CLBL-1 Canis lupus familiaris
AZD1480 Flow cytometr- annexin V staining Influence on cell apoptosis 5.00 µM CLBL-1 Canis lupus familiaris
AZD1480 Flow cytometr- annexin V staining Influence on cell apoptosis 2.00 µM MDCK Canis lupus familiaris
AZD1480 Flow cytometr- annexin V staining Influence on cell apoptosis 5.00 µM MDCK Canis lupus familiaris
AZD1480 Ki67/DAPI cell proliferation assay Influence on cell cycle 2.00 µM CLBL-1 Canis lupus familiaris
AZD1480 Western Blot Influence on protein activity 0.00 µM Ba/F3 TEL-JAK2 Mus musculus p-STAT5
AZD1480 Western Blot Influence on protein activity 0.01 µM Ba/F3 TEL-JAK2 Mus musculus p-STAT5
AZD1480 Western Blot Influence on protein activity 0.03 µM Ba/F3 TEL-JAK2 Mus musculus p-STAT5
AZD1480 Western Blot Influence on protein activity 0.10 µM Ba/F3 TEL-JAK2 Mus musculus p-STAT5
AZD1480 Western Blot Influence on protein activity 0.30 µM Ba/F3 TEL-JAK2 Mus musculus p-STAT5
AZD1480 Western Blot Influence on protein activity 1.00 µM Ba/F3 TEL-JAK2 Mus musculus p-STAT5
AZD1480 Western Blot Influence on protein activity 3.00 µM Ba/F3 TEL-JAK2 Mus musculus p-STAT5
AZD1480 Western Blot Influence on protein activity 0.00 µM Ba/F3 TEL-JAK2 Mus musculus STAT5
AZD1480 Western Blot Influence on protein activity 0.01 µM Ba/F3 TEL-JAK2 Mus musculus STAT5
AZD1480 Western Blot Influence on protein activity 0.03 µM Ba/F3 TEL-JAK2 Mus musculus STAT5
AZD1480 Western Blot Influence on protein activity 0.10 µM Ba/F3 TEL-JAK2 Mus musculus STAT5
AZD1480 Western Blot Influence on protein activity 0.30 µM Ba/F3 TEL-JAK2 Mus musculus STAT5
AZD1480 Western Blot Influence on protein activity 1.00 µM Ba/F3 TEL-JAK2 Mus musculus STAT5
AZD1480 Western Blot Influence on protein activity 3.00 µM Ba/F3 TEL-JAK2 Mus musculus STAT5
AZD1480 Western Blot Influence on protein activity 0.00 µM Ba/F3 TEL-TYK2 Mus musculus p-STAT5
AZD1480 Western Blot Influence on protein activity 0.01 µM Ba/F3 TEL-TYK2 Mus musculus p-STAT5
AZD1480 Western Blot Influence on protein activity 0.03 µM Ba/F3 TEL-TYK2 Mus musculus p-STAT5
AZD1480 Western Blot Influence on protein activity 0.10 µM Ba/F3 TEL-TYK2 Mus musculus p-STAT5
AZD1480 Western Blot Influence on protein activity 0.30 µM Ba/F3 TEL-TYK2 Mus musculus p-STAT5
AZD1480 Western Blot Influence on protein activity 1.00 µM Ba/F3 TEL-TYK2 Mus musculus p-STAT5
AZD1480 Western Blot Influence on protein activity 3.00 µM Ba/F3 TEL-TYK2 Mus musculus p-STAT5
AZD1480 Western Blot Influence on protein activity 0.00 µM Ba/F3 TEL-TYK2 Mus musculus STAT5
AZD1480 Western Blot Influence on protein activity 0.01 µM Ba/F3 TEL-TYK2 Mus musculus STAT5
AZD1480 Western Blot Influence on protein activity 0.03 µM Ba/F3 TEL-TYK2 Mus musculus STAT5
AZD1480 Western Blot Influence on protein activity 0.10 µM Ba/F3 TEL-TYK2 Mus musculus STAT5
AZD1480 Western Blot Influence on protein activity 0.30 µM Ba/F3 TEL-TYK2 Mus musculus STAT5
AZD1480 Western Blot Influence on protein activity 1.00 µM Ba/F3 TEL-TYK2 Mus musculus STAT5
AZD1480 Western Blot Influence on protein activity 3.00 µM Ba/F3 TEL-TYK2 Mus musculus STAT5
AZD1480 Western Blot Influence on protein activity 0.00 µM Ba/F3 TEL-JAK3 Mus musculus p-STAT5
AZD1480 Western Blot Influence on protein activity 0.01 µM Ba/F3 TEL-JAK3 Mus musculus p-STAT5
AZD1480 Western Blot Influence on protein activity 0.03 µM Ba/F3 TEL-JAK3 Mus musculus p-STAT5
AZD1480 Western Blot Influence on protein activity 0.10 µM Ba/F3 TEL-JAK3 Mus musculus p-STAT5
AZD1480 Western Blot Influence on protein activity 0.30 µM Ba/F3 TEL-JAK3 Mus musculus p-STAT5
AZD1480 Western Blot Influence on protein activity 1.00 µM Ba/F3 TEL-JAK3 Mus musculus p-STAT5
AZD1480 Western Blot Influence on protein activity 3.00 µM Ba/F3 TEL-JAK3 Mus musculus p-STAT5
AZD1480 Western Blot Influence on protein activity 0.00 µM Ba/F3 TEL-JAK3 Mus musculus STAT5
AZD1480 Western Blot Influence on protein activity 0.01 µM Ba/F3 TEL-JAK3 Mus musculus STAT5
AZD1480 Western Blot Influence on protein activity 0.03 µM Ba/F3 TEL-JAK3 Mus musculus STAT5
AZD1480 Western Blot Influence on protein activity 0.10 µM Ba/F3 TEL-JAK3 Mus musculus STAT5
AZD1480 Western Blot Influence on protein activity 0.30 µM Ba/F3 TEL-JAK3 Mus musculus STAT5
AZD1480 Western Blot Influence on protein activity 1.00 µM Ba/F3 TEL-JAK3 Mus musculus STAT5
AZD1480 Western Blot Influence on protein activity 3.00 µM Ba/F3 TEL-JAK3 Mus musculus STAT5
AZD1480 Western Blot Influence on protein activity 0.00 µM Ba/F3 TEL-JAK1 Mus musculus p-STAT5
AZD1480 Western Blot Influence on protein activity 0.01 µM Ba/F3 TEL-JAK1 Mus musculus p-STAT5
AZD1480 Western Blot Influence on protein activity 0.03 µM Ba/F3 TEL-JAK1 Mus musculus p-STAT5
AZD1480 Western Blot Influence on protein activity 0.10 µM Ba/F3 TEL-JAK1 Mus musculus p-STAT5
AZD1480 Western Blot Influence on protein activity 0.30 µM Ba/F3 TEL-JAK1 Mus musculus p-STAT5
AZD1480 Western Blot Influence on protein activity 1.00 µM Ba/F3 TEL-JAK1 Mus musculus p-STAT5
AZD1480 Western Blot Influence on protein activity 3.00 µM Ba/F3 TEL-JAK1 Mus musculus p-STAT5
AZD1480 Western Blot Influence on protein activity 0.00 µM Ba/F3 TEL-JAK1 Mus musculus STAT5
AZD1480 Western Blot Influence on protein activity 0.01 µM Ba/F3 TEL-JAK1 Mus musculus STAT5
AZD1480 Western Blot Influence on protein activity 0.03 µM Ba/F3 TEL-JAK1 Mus musculus STAT5
AZD1480 Western Blot Influence on protein activity 0.10 µM Ba/F3 TEL-JAK1 Mus musculus STAT5
AZD1480 Western Blot Influence on protein activity 0.30 µM Ba/F3 TEL-JAK1 Mus musculus STAT5
AZD1480 Western Blot Influence on protein activity 1.00 µM Ba/F3 TEL-JAK1 Mus musculus STAT5
AZD1480 Western Blot Influence on protein activity 3.00 µM Ba/F3 TEL-JAK1 Mus musculus STAT5
AZD1480 Western Blot Influence on protein activity 0.30 µM NCI-H1650 Homo sapiens p-STAT3
AZD1480 Western Blot Influence on protein activity 0.30 µM NCI-H1650 Homo sapiens STAT3
AZD1480 Western Blot Influence on protein activity 0.30 µM HCC 827 Homo sapiens p-STAT3
AZD1480 Western Blot Influence on protein activity 0.30 µM HCC 827 Homo sapiens STAT3
AZD1480 Western Blot Influence on protein activity 0.30 µM AGS Homo sapiens p-STAT3
AZD1480 Western Blot Influence on protein activity 0.30 µM AGS Homo sapiens STAT3
AZD1480 Western Blot Influence on protein activity in presence of IL-6 0.30 µM Hep3B Homo sapiens p-STAT3
AZD1480 Western Blot Influence on protein activity in presence of IL-6 0.30 µM Hep3B Homo sapiens STAT3
AZD1480 Western Blot Influence on protein activity in presence of OSM 0.10 µM MEF-Stat3-YFP Mus musculus p-STAT3 (Y705)
AZD1480 Western Blot Influence on protein activity in presence of OSM 0.50 µM MEF-Stat3-YFP Mus musculus p-STAT3 (Y705)
AZD1480 Western Blot Influence on protein activity in presence of OSM 1.00 µM MEF-Stat3-YFP Mus musculus p-STAT3 (Y705)
AZD1480 Western Blot Influence on protein activity in presence of OSM 0.10 µM MEF-Stat3-YFP Mus musculus STAT3
AZD1480 Western Blot Influence on protein activity in presence of OSM 0.50 µM MEF-Stat3-YFP Mus musculus STAT3
AZD1480 Western Blot Influence on protein activity in presence of OSM 1.00 µM MEF-Stat3-YFP Mus musculus STAT3
AZD1480 Western Blot Influence on protein activity in presence of OSM 0.10 µM MEF-Stat3-YFP Mus musculus
AZD1480 Western Blot Influence on protein activity in presence of OSM 0.50 µM MEF-Stat3-YFP Mus musculus
AZD1480 Western Blot Influence on protein activity in presence of OSM 1.00 µM MEF-Stat3-YFP Mus musculus
AZD1480 Western Blot Influence on protein activity in presence of OSM 0.10 µM MEF-Stat3-YFP Mus musculus
AZD1480 Western Blot Influence on protein activity in presence of OSM 0.50 µM MEF-Stat3-YFP Mus musculus
AZD1480 Western Blot Influence on protein activity in presence of OSM 1.00 µM MEF-Stat3-YFP Mus musculus
AZD1480 Western Blot Influence on protein activity in presence of OSM 0.10 µM MEF-Stat3-YFP Mus musculus
AZD1480 Western Blot Influence on protein activity in presence of OSM 0.50 µM MEF-Stat3-YFP Mus musculus
AZD1480 Western Blot Influence on protein activity in presence of OSM 1.00 µM MEF-Stat3-YFP Mus musculus
AZD1480 Western Blot Influence on protein activity in presence of OSM 0.10 µM MEF-Stat3-YFP Mus musculus
AZD1480 Western Blot Influence on protein activity in presence of OSM 0.50 µM MEF-Stat3-YFP Mus musculus
AZD1480 Western Blot Influence on protein activity in presence of OSM 1.00 µM MEF-Stat3-YFP Mus musculus
AZD1480 Western Blot Influence on protein activity in presence of OSM 0.10 µM MEF-Stat3-YFP Mus musculus
AZD1480 Western Blot Influence on protein activity in presence of OSM 0.50 µM MEF-Stat3-YFP Mus musculus
AZD1480 Western Blot Influence on protein activity in presence of OSM 1.00 µM MEF-Stat3-YFP Mus musculus
AZD1480 Immunofluorescence Influence on protein translocation in presence of OSM 0.10 µM MEF-Stat3-YFP Mus musculus STAT3
AZD1480 Immunofluorescence Influence on protein translocation in presence of OSM 0.50 µM MEF-Stat3-YFP Mus musculus STAT3
AZD1480 Immunofluorescence Influence on protein translocation in presence of OSM 1.00 µM MEF-Stat3-YFP Mus musculus STAT3
AZD1480 Tumor volume Influence on cell proliferation in tumor tissue 50.00 mg/kg MEF-Stat3-YFP Mus musculus
AZD1480 Western Blot Influence on protein activity 0.05 µM LN-17 Homo sapiens p-STAT3 (Y705)
AZD1480 Western Blot Influence on protein activity 0.10 µM LN-17 Homo sapiens p-STAT3 (Y705)
AZD1480 Western Blot Influence on protein activity 0.25 µM LN-17 Homo sapiens p-STAT3 (Y705)
AZD1480 Western Blot Influence on protein activity 0.50 µM LN-17 Homo sapiens p-STAT3 (Y705)
AZD1480 Western Blot Influence on protein activity 1.00 µM LN-17 Homo sapiens p-STAT3 (Y705)
AZD1480 Western Blot Influence on protein activity 0.05 µM LN-17 Homo sapiens
AZD1480 Western Blot Influence on protein activity 0.10 µM LN-17 Homo sapiens
AZD1480 Western Blot Influence on protein activity 0.25 µM LN-17 Homo sapiens
AZD1480 Western Blot Influence on protein activity 0.50 µM LN-17 Homo sapiens
AZD1480 Western Blot Influence on protein activity 1.00 µM LN-17 Homo sapiens
AZD1480 EMSA Influence on protein-DNA interaction 0.10 µM LN-17 Homo sapiens STAT3:STAT3
AZD1480 EMSA Influence on protein-DNA interaction 0.50 µM LN-17 Homo sapiens STAT3:STAT3
AZD1480 EMSA Influence on protein-DNA interaction 1.00 µM LN-17 Homo sapiens STAT3:STAT3
AZD1480 MTS Assay Influence on cell viability 0.10 µM LN-17 Homo sapiens
AZD1480 MTS Assay Influence on cell viability 0.50 µM LN-17 Homo sapiens
AZD1480 MTS Assay Influence on cell viability 1.00 µM LN-17 Homo sapiens
AZD1480 Flow cytometry- annexin V staining Influence on cell apoptosis 0.10 µM LN-17 Homo sapiens
AZD1480 Flow cytometry- annexin V staining Influence on cell apoptosis 0.50 µM LN-17 Homo sapiens
AZD1480 Flow cytometry- annexin V staining Influence on cell apoptosis 1.00 µM LN-17 Homo sapiens
AZD1480 Western Blot Influence on cell apoptosis 0.10 µM LN-17 Homo sapiens
AZD1480 Western Blot Influence on cell apoptosis 0.50 µM LN-17 Homo sapiens
AZD1480 Western Blot Influence on cell apoptosis 1.00 µM LN-17 Homo sapiens
AZD1480 Western Blot Influence on cell apoptosis 0.10 µM LN-17 Homo sapiens
AZD1480 Western Blot Influence on cell apoptosis 0.50 µM LN-17 Homo sapiens
AZD1480 Western Blot Influence on cell apoptosis 1.00 µM LN-17 Homo sapiens
AZD1480 Western Blot Influence on protein activity 0.05 µM MDAH2774 Homo sapiens p-STAT3 (Y705)
AZD1480 Western Blot Influence on protein activity 0.10 µM MDAH2774 Homo sapiens p-STAT3 (Y705)
AZD1480 Western Blot Influence on protein activity 0.25 µM MDAH2774 Homo sapiens p-STAT3 (Y705)
AZD1480 Western Blot Influence on protein activity 0.50 µM MDAH2774 Homo sapiens p-STAT3 (Y705)
AZD1480 Western Blot Influence on protein activity 1.00 µM MDAH2774 Homo sapiens p-STAT3 (Y705)
AZD1480 Western Blot Influence on protein activity 0.05 µM MDAH2774 Homo sapiens STAT3
AZD1480 Western Blot Influence on protein activity 0.10 µM MDAH2774 Homo sapiens STAT3
AZD1480 Western Blot Influence on protein activity 0.25 µM MDAH2774 Homo sapiens
AZD1480 Western Blot Influence on protein activity 0.50 µM MDAH2774 Homo sapiens STAT3
AZD1480 Western Blot Influence on protein activity 1.00 µM MDAH2774 Homo sapiens STAT3
AZD1480 Western Blot Influence on protein activity 0.05 µM MDAH2774 Homo sapiens
AZD1480 Western Blot Influence on protein activity 0.10 µM MDAH2774 Homo sapiens
AZD1480 Western Blot Influence on protein activity 0.25 µM MDAH2774 Homo sapiens
AZD1480 Western Blot Influence on protein activity 0.50 µM MDAH2774 Homo sapiens
AZD1480 Western Blot Influence on protein activity 1.00 µM MDAH2774 Homo sapiens
AZD1480 Western Blot Influence on protein activity 0.10 µM MDA-MB-468 Homo sapiens p-STAT3 (Y705)
AZD1480 Western Blot Influence on protein activity 0.50 µM MDA-MB-468 Homo sapiens p-STAT3 (Y705)
AZD1480 Western Blot Influence on protein activity 1.00 µM MDA-MB-468 Homo sapiens p-STAT3 (Y705)
AZD1480 Western Blot Influence on protein activity 0.10 µM MDA-MB-468 Homo sapiens
AZD1480 Western Blot Influence on protein activity 0.50 µM MDA-MB-468 Homo sapiens
AZD1480 Western Blot Influence on protein activity 1.00 µM MDA-MB-468 Homo sapiens
AZD1480 Western Blot Influence on protein activity 0.10 µM DU145 Homo sapiens p-STAT3 (Y705)
AZD1480 Western Blot Influence on protein activity 0.25 µM DU145 Homo sapiens p-STAT3 (Y705)
AZD1480 Western Blot Influence on protein activity 0.50 µM DU145 Homo sapiens p-STAT3 (Y705)
AZD1480 Western Blot Influence on protein activity 1.00 µM DU145 Homo sapiens p-STAT3 (Y705)
AZD1480 Western Blot Influence on protein activity 0.10 µM DU145 Homo sapiens STAT3
AZD1480 Western Blot Influence on protein activity 0.25 µM DU145 Homo sapiens STAT3
AZD1480 Western Blot Influence on protein activity 0.50 µM DU145 Homo sapiens STAT3
AZD1480 Western Blot Influence on protein activity 1.00 µM DU145 Homo sapiens STAT3
AZD1480 Western Blot Influence on protein activity 0.10 µM DU145 Homo sapiens
AZD1480 Western Blot Influence on protein activity 0.25 µM DU145 Homo sapiens
AZD1480 Western Blot Influence on protein activity 0.50 µM DU145 Homo sapiens
AZD1480 Western Blot Influence on protein activity 1.00 µM DU145 Homo sapiens
AZD1480 Western Blot Influence on protein activity in presence of IL-6 3.00 µM MDAH2774 Homo sapiens p-STAT3 (Y705)
AZD1480 Western Blot Influence on protein activity in presence of IL-6 0.30 µM MDAH2774 Homo sapiens STAT3
AZD1480 Western Blot Influence on protein activity in presence of IL-6 0.10 µM MDA-MB-468 Homo sapiens p-STAT3 (Y705)
AZD1480 Western Blot Influence on protein activity in presence of IL-6 0.50 µM MDA-MB-468 Homo sapiens p-STAT3 (Y705)
AZD1480 Western Blot Influence on protein activity in presence of IL-6 1.00 µM MDA-MB-468 Homo sapiens p-STAT3 (Y705)
AZD1480 Western Blot Influence on protein activity in presence of IL-6 0.10 µM MDA-MB-468 Homo sapiens
AZD1480 Western Blot Influence on protein activity in presence of IL-6 0.50 µM MDA-MB-468 Homo sapiens
AZD1480 Western Blot Influence on protein activity in presence of IL-6 1.00 µM MDA-MB-468 Homo sapiens
AZD1480 Western Blot Influence on protein activity in presence of IL-6 0.10 µM DU145 Homo sapiens p-STAT3 (Y705)
AZD1480 Western Blot Influence on protein activity in presence of IL-6 0.50 µM DU145 Homo sapiens p-STAT3 (Y705)
AZD1480 Western Blot Influence on protein activity in presence of IL-6 1.00 µM DU145 Homo sapiens p-STAT3 (Y705)
AZD1480 Western Blot Influence on protein activity in presence of IL-6 0.10 µM DU145 Homo sapiens
AZD1480 Western Blot Influence on protein activity in presence of IL-6 0.50 µM DU145 Homo sapiens
AZD1480 Western Blot Influence on protein activity in presence of IL-6 1.00 µM DU145 Homo sapiens
AZD1480 Tumor volume Influence on cell proliferation in tumor tissue 50.00 mg/kg DU145 (xenograft) Mus musculus
AZD1480 Tumor volume Influence on cell proliferation in tumor tissue 50.00 mg/kg MDA-MB-468 (xenograft) Mus musculus
AZD1480 Tumor volume Influence on cell proliferation in tumor tissue 1.00 mg/kg MDAH2774 (xenograft) Mus musculus
AZD1480 Tumor volume Influence on cell proliferation in tumor tissue 10.00 mg/kg MDAH2774 (xenograft) Mus musculus
AZD1480 Tumor volume Influence on cell proliferation in tumor tissue 50.00 mg/kg MDAH2774 (xenograft) Mus musculus
AZD1480 Western Blot Influence on protein activity in tumor tissue 50.00 mg/kg DU145 (xenograft) Mus musculus p-STAT3 (Y705)
AZD1480 Western Blot Influence on protein activity in tumor tissue 50.00 mg/kg DU145 (xenograft) Mus musculus
AZD1480 Western Blot Influence on protein activity in tumor tissue 50.00 mg/kg MDA-MB-468 (xenograft) Mus musculus p-STAT3 (Y705)
AZD1480 Western Blot Influence on protein activity in tumor tissue 50.00 mg/kg MDA-MB-468 (xenograft) Mus musculus STAT3
AZD1480 Western Blot Influence on protein activity in tumor tissue 50.00 mg/kg MDA-MB-468 (xenograft) Mus musculus
AZD1480 Western Blot Influence on protein activity in tumor tissue 50.00 mg/kg MDAH2774 (xenograft) Mus musculus p-STAT3 (Y705)
AZD1480 Western Blot Influence on protein activity in tumor tissue 50.00 mg/kg MDAH2774 (xenograft) Mus musculus STAT3
AZD1480 Western Blot Influence on protein activity in tumor tissue 50.00 mg/kg MDAH2774 (xenograft) Mus musculus
AZD1480 Western Blot Influence on protein activity in tumor tissue 50.00 mg/kg MDAH2774 (xenograft) Mus musculus
AZD1480 Western Blot Influence on protein activity in tumor tissue 50.00 mg/kg MDAH2774 (xenograft) Mus musculus
AZD1480 Western Blot Influence on protein activity in tumor tissue 50.00 mg/kg MDAH2774 (xenograft) Mus musculus
AZD1480 Western Blot Influence on protein activity in tumor tissue 50.00 mg/kg MDAH2774 (xenograft) Mus musculus
AZD1480 SRB assay Influence on cell proliferation 1.00 µM TPC-1 Homo sapiens
AZD1480 SRB assay Influence on cell proliferation 1.00 µM MZ-CRC1 Homo sapiens
AZD1480 SRB assay Influence on cell proliferation 1.00 µM TT Homo sapiens
AZD1480 SRB assay Influence on cell proliferation 1.00 µM PCCI3 Rattus norvegicus
AZD1480 Flow cytometry Influence on cell cycle 1.00 µM TPC-1 Homo sapiens
AZD1480 Flow cytometry Influence on cell cycle 1.00 µM MZ-CRC1 Homo sapiens
AZD1480 Flow cytometry Influence on cell cycle 1.00 µM TT Homo sapiens
AZD1480 TUNEL Influence on cell apoptosis 1.00 µM TPC-1 Homo sapiens
AZD1480 TUNEL Influence on cell apoptosis 1.00 µM MZ-CRC1 Homo sapiens
AZD1480 TUNEL Influence on cell apoptosis 1.00 µM TT Homo sapiens
AZD1480 Western Blot Influence on cell apoptosis 1.00 µM TPC-1 Homo sapiens
AZD1480 Western Blot Influence on cell apoptosis 1.00 µM MZ-CRC1 Homo sapiens
AZD1480 Western Blot Influence on cell apoptosis 1.00 µM TT Homo sapiens
AZD1480 Western Blot Influence on cell apoptosis 1.00 µM TPC-1 Homo sapiens
AZD1480 Western Blot Influence on cell apoptosis 1.00 µM MZ-CRC1 Homo sapiens
AZD1480 Western Blot Influence on cell apoptosis 1.00 µM TT Homo sapiens
AZD1480 Western Blot Influence on cell apoptosis 1.00 µM TPC-1 Homo sapiens
AZD1480 Western Blot Influence on cell apoptosis 1.00 µM MZ-CRC1 Homo sapiens
AZD1480 Western Blot Influence on cell apoptosis 1.00 µM TT Homo sapiens
AZD1480 Western Blot Influence on cell apoptosis 1.00 µM TPC-1 Homo sapiens
AZD1480 Western Blot Influence on cell apoptosis 1.00 µM MZ-CRC1 Homo sapiens
AZD1480 Western Blot Influence on cell apoptosis 1.00 µM TT Homo sapiens
AZD1480 Tumor volume Influence on cell proliferation in tumor tissue 30.00 mg/kg TPC-1 (xenograft) Mus musclus
AZD1480 Immunostaining Influence on cell proliferation in tumor tissue 30.00 mg/kg TPC-1 (xenograft) Mus musclus nu/nu Nude mice
AZD1480 Immunostaining Influence on cell proliferation in tumor tissue 30.00 mg/kg TPC-1 (xenograft) Mus musclus nu/nu Nude mice
AZD1480 Immunostaining Influence on cell proliferation in tumor tissue 30.00 mg/kg TPC-1 (xenograft) Mus musclus nu/nu Nude mice
AZD1480 Western Blot Influence on protein activity 1.00 µM TPC-1 Homo sapiens p-STAT3 (Y705)
AZD1480 Western Blot Influence on protein activity 1.00 µM TPC-1 Homo sapiens STAT3
AZD1480 Western Blot Influence on protein activity 1.00 µM TPC-1 Homo sapiens
AZD1480 Western Blot Influence on protein activity 1.00 µM TPC-1 Homo sapiens
AZD1480 Western Blot Influence on protein activity 1.00 µM TPC-1 Homo sapiens
AZD1480 Western Blot Influence on protein activity 1.00 µM TPC-1 Homo sapiens
AZD1480 Western Blot Influence on protein activity 1.00 µM TPC-1 Homo sapiens
AZD1480 Western Blot Influence on protein activity 1.00 µM TPC-1 Homo sapiens
AZD1480 Western Blot Influence on protein activity 1.00 µM TPC-1 Homo sapiens
AZD1480 Western Blot Influence on protein activity 1.00 µM MZ-CRC1 Homo sapiens p-STAT3 (Y705)
AZD1480 Western Blot Influence on protein activity 1.00 µM MZ-CRC1 Homo sapiens STAT3
AZD1480 Western Blot Influence on protein activity 1.00 µM MZ-CRC1 Homo sapiens
AZD1480 Western Blot Influence on protein activity 1.00 µM MZ-CRC1 Homo sapiens
AZD1480 Western Blot Influence on protein activity 1.00 µM MZ-CRC1 Homo sapiens
AZD1480 Western Blot Influence on protein activity 1.00 µM MZ-CRC1 Homo sapiens
AZD1480 Western Blot Influence on protein activity 1.00 µM MZ-CRC1 Homo sapiens
AZD1480 Western Blot Influence on protein activity 1.00 µM MZ-CRC1 Homo sapiens
AZD1480 Western Blot Influence on protein activity 1.00 µM MZ-CRC1 Homo sapiens
AZD1480 Western Blot Influence on protein activity 1.00 µM MZ-CRC1 Homo sapiens
AZD1480 Western Blot Influence on protein activity 1.00 µM TT Homo sapiens p-STAT3 (Y705)
AZD1480 Western Blot Influence on protein activity 1.00 µM TT Homo sapiens STAT3
AZD1480 Western Blot Influence on protein activity 1.00 µM TT Homo sapiens
AZD1480 Western Blot Influence on protein activity 1.00 µM TT Homo sapiens
AZD1480 Western Blot Influence on protein activity 1.00 µM TT Homo sapiens
AZD1480 Western Blot Influence on protein activity 1.00 µM TT Homo sapiens
AZD1480 Western Blot Influence on protein activity 1.00 µM TT Homo sapiens
AZD1480 Western Blot Influence on protein activity 1.00 µM TT Homo sapiens
AZD1480 Western Blot Influence on protein activity 1.00 µM TT Homo sapiens
AZD1480 Western Blot Influence on protein activity 1.00 µM TT Homo sapiens
AZD1480 Western Blot Influence on protein activity 1.00 µM TPC-1 Homo sapiens
AZD1480 Western Blot Influence on protein activity 1.00 µM PCCl3-RET/PTC3 Rattus norvegicus p-STAT3 (Y705)
AZD1480 Western Blot Influence on protein activity 1.00 µM PCCl3-RET/PTC3 Rattus norvegicus STAT3
AZD1480 Western Blot Influence on protein activity 1.00 µM PCCl3-RET/PTC3 Rattus norvegicus
AZD1480 Western Blot Influence on protein activity 1.00 µM PCCl3-RET/PTC3 Rattus norvegicus
AZD1480 Western Blot Influence on protein activity 1.00 µM PCCl3-RET/PTC3 Rattus norvegicus
AZD1480 Western Blot Influence on protein activity 1.00 µM PCCl3-RET/PTC3 Rattus norvegicus
AZD1480 Western Blot Influence on protein activity 1.00 µM PCCl3-RET/PTC3 Rattus norvegicus
AZD1480 Western Blot Influence on protein activity 1.00 µM PCCl3-RET/PTC3 Rattus norvegicus
AZD1480 Western Blot Influence on protein activity 1.00 µM PCCl3-RET/PTC3 Rattus norvegicus
AZD1480 Western Blot Influence on protein activity 1.00 µM PCCl3-RET/PTC3 Rattus norvegicus
AZD1480 MTS Assay Influence on cell viability 0.50 µM 786-O Mus musclus
AZD1480 MTS Assay Influence on cell viability 1.00 µM 786-O Mus musclus
AZD1480 MTS Assay Influence on cell viability 0.50 µM Renca Mus musclus
AZD1480 MTS Assay Influence on cell viability 1.00 µM Renca Mus musclus
AZD1480 Western Blot Influence on protein activity 0.50 µM 786-O Mus musclus p-STAT3
AZD1480 Western Blot Influence on protein activity 1.00 µM 786-O Mus musclus p-STAT3
AZD1480 Western Blot Influence on protein activity 0.50 µM 786-O Mus musclus STAT3
AZD1480 Western Blot Influence on protein activity 1.00 µM 786-O Mus musclus STAT3
AZD1480 Western Blot Influence on protein activity 0.50 µM Renca Mus musclus p-STAT3
AZD1480 Western Blot Influence on protein activity 1.00 µM Renca Mus musclus p-STAT3
AZD1480 Western Blot Influence on protein activity 0.50 µM Renca Mus musclus STAT3
AZD1480 Western Blot Influence on protein activity 1.00 µM Renca Mus musclus STAT3
AZD1480 Tumor volume Influence on cell proliferation in tumor tissue 50.00 mg/kg Renca (xenograft0 Mus musclus BALB/c
AZD1480 Western Blot Influence on protein activity in tumor tissue 50.00 mg/kg Renca (xenograft0 Mus musclus BALB/c p-STAT3
AZD1480 Western Blot Influence on protein activity in tumor tissue 50.00 mg/kg Renca (xenograft0 Mus musclus BALB/c STAT3
AZD1480 Western Blot Influence on protein activity in tumor tissue 50.00 mg/kg Renca (xenograft0 Mus musclus BALB/c
AZD1480 Western Blot Influence on protein activity in tumor tissue 50.00 mg/kg Renca (xenograft0 Mus musclus BALB/c
AZD1480 Western Blot Influence on protein activity in tumor tissue 50.00 mg/kg Renca (xenograft0 Mus musclus BALB/c
AZD1480 Immunostaining Influence on angiogenesis 50.00 mg/kg Renca (xenograft0 Mus musclus BALB/c
AZD1480 Immunostaining Influence on angiogenesis 50.00 mg/kg Renca (xenograft0 Mus musclus BALB/c
AZD1480 Immunostaining Influence on angiogenesis 50.00 mg/kg Renca (xenograft0 Mus musclus BALB/c
AZD1480 Immunostaining Influence on angiogenesis 50.00 mg/kg Renca (xenograft0 Mus musclus BALB/c
AZD1480 Tube formation assay Influence on cell motility 0.10 µM EC Mus musclus BALB/c
AZD1480 Tube formation assay Influence on cell motility 0.50 µM EC Mus musclus BALB/c
AZD1480 Tube formation assay Influence on cell motility 1.00 µM EC Mus musclus BALB/c
AZD1480 Tube formation assay Influence on cell motility 0.10 µM HUVEC Homo sapiens BALB/c
AZD1480 Tube formation assay Influence on cell motility 0.50 µM HUVEC Homo sapiens BALB/c
AZD1480 Tube formation assay Influence on cell motility 1.00 µM HUVEC Homo sapiens BALB/c
AZD1480 Number of nodules Influence on tumor metastasis 50.00 mg/kg Renca Mus musclus BALB/c
AZD1480 Western Blot Influence on protein activity in metastatic tumor 50.00 mg/kg Renca Mus musclus BALB/c p-STAT3
AZD1480 Western Blot Influence on protein activity in metastatic tumor 50.00 mg/kg Renca Mus musclus BALB/c STAT3
AZD1480 Western Blot Influence on protein activity in metastatic tumor 50.00 mg/kg Renca Mus musclus BALB/c
AZD1480 Western Blot Influence on protein activity in metastatic tumor 50.00 mg/kg Renca Mus musclus BALB/c
AZD1480 Western Blot Influence on protein activity in metastatic tumor 50.00 mg/kg Renca Mus musclus BALB/c
AZD1480 MTS Assay Cell viability inhibition 0.50 µM U266 Homo sapiens
AZD1480 MTS Assay Cell viability inhibition 0.50 µM RPMI 8226 Homo sapiens
AZD1480 MTS Assay Cell viability inhibition 0.50 µM Kms.11 Homo sapiens
AZD1480 MTS Assay Cell viability inhibition 1.00 µM U266 Homo sapiens
AZD1480 MTS Assay Cell viability inhibition 1.00 µM RPMI 8226 Homo sapiens
AZD1480 MTS Assay Cell viability inhibition 1.00 µM Kms.11 Homo sapiens
AZD1480 MTS Assay Cell viability inhibition 2.00 µM U266 Homo sapiens
AZD1480 MTS Assay Cell viability inhibition 2.00 µM RPMI 8226 Homo sapiens
AZD1480 MTS Assay Cell viability inhibition 2.00 µM Kms.11 Homo sapiens
AZD1480 MTS Assay Cell viability inhibition 3.00 µM U266 Homo sapiens
AZD1480 MTS Assay Cell viability inhibition 3.00 µM RPMI 8226 Homo sapiens
AZD1480 MTS Assay Cell viability inhibition 3.00 µM Kms.11 Homo sapiens
AZD1480 Flow cytometry Cell Apoptosis Analysis 0.50 µM U266 Homo sapiens
AZD1480 Flow cytometry Cell Apoptosis Analysis 0.50 µM Kms.11 Homo sapiens
AZD1480 Flow cytometry Cell Apoptosis Analysis 0.80 µM U266 Homo sapiens
AZD1480 Flow cytometry Cell Apoptosis Analysis 0.80 µM Kms.11 Homo sapiens
AZD1480 Flow cytometry Cell Apoptosis Analysis 1.00 µM U266 Homo sapiens
AZD1480 Flow cytometry Cell Apoptosis Analysis 1.00 µM Kms.11 Homo sapiens
AZD1480 Flow cytometry Cell Apoptosis Analysis 1.50 µM U266 Homo sapiens
AZD1480 Flow cytometry Cell Apoptosis Analysis 1.50 µM Kms.11 Homo sapiens
AZD1480 Flow cytometry Cell Apoptosis Analysis 2.00 µM U266 Homo sapiens
AZD1480 Flow cytometry Cell Apoptosis Analysis 2.00 µM RPMI 8226 Homo sapiens
AZD1480 Flow cytometry Cell Apoptosis Analysis 2.00 µM Kms.11 Homo sapiens
AZD1480 Flow cytometry Cell Apoptosis Analysis 3.00 µM RPMI 8226 Homo sapiens
AZD1480 DIMSCAN analysis Cell Viability 1.00 µM PBMC Mus musculus
AZD1480 DIMSCAN analysis Cell Viability 2.00 µM PBMC Mus musculus
AZD1480 MTS Assay Cell viability inhibition in presence of IL6 0.50 µM Kms.11 Homo sapiens
AZD1480 MTS Assay Cell viability inhibition in presence of IL6 0.50 µM U266 Homo sapiens
AZD1480 MTS Assay Cell viability inhibition in presence of IL6 1.00 µM Kms.11 Homo sapiens
AZD1480 MTS Assay Cell viability inhibition in presence of IL6 1.00 µM U266 Homo sapiens
AZD1480 MTS Assay Cell viability inhibition in presence of IL6 2.00 µM Kms.11 Homo sapiens
AZD1480 MTS Assay Cell viability inhibition in presence of IL6 2.00 µM U266 Homo sapiens
AZD1480 MTS Assay Cell viability inhibition in presence of IL6 3.00 µM Kms.11 Homo sapiens
AZD1480 MTS Assay Cell viability inhibition in presence of IL6 3.00 µM U266 Homo sapiens
AZD1480 Immunoprecipitation Influence on protein activity in presence of IL6 0.50 µM U266 Homo sapiens
AZD1480 Immunoprecipitation Influence on protein activity in presence of IL6 1.00 µM U266 Homo sapiens
AZD1480 Immunoprecipitation Influence on protein activity in presence of IL6 0.50 µM U266 Homo sapiens
AZD1480 Immunoprecipitation Influence on protein activity in presence of IL6 1.00 µM U266 Homo sapiens
AZD1480 Immunoprecipitation Influence on protein activity in presence of IL6 0.25 µM Kms.11 Homo sapiens
AZD1480 Immunoprecipitation Influence on protein activity in presence of IL6 0.50 µM Kms.11 Homo sapiens
AZD1480 Immunoprecipitation Influence on protein activity in presence of IL6 1.00 µM Kms.11 Homo sapiens
AZD1480 Immunoprecipitation Influence on protein activity in presence of IL6 0.25 µM Kms.11 Homo sapiens
AZD1480 Immunoprecipitation Influence on protein activity in presence of IL6 0.50 µM Kms.11 Homo sapiens
AZD1480 Immunoprecipitation Influence on protein activity in presence of IL6 1.00 µM Kms.11 Homo sapiens
AZD1480 Immunoprecipitation Influence on protein activity in presence of IL6 0.50 µM U266 Homo sapiens
AZD1480 Immunoprecipitation Influence on protein activity in presence of IL6 1.00 µM U266 Homo sapiens
AZD1480 Immunoprecipitation Influence on protein activity in presence of IL6 0.50 µM U266 Homo sapiens
AZD1480 Immunoprecipitation Influence on protein activity in presence of IL6 1.00 µM U266 Homo sapiens
AZD1480 Immunoprecipitation Influence on protein activity in presence of IL6 0.25 µM Kms.11 Homo sapiens
AZD1480 Immunoprecipitation Influence on protein activity in presence of IL6 0.50 µM Kms.11 Homo sapiens
AZD1480 Immunoprecipitation Influence on protein activity in presence of IL6 1.00 µM Kms.11 Homo sapiens
AZD1480 Immunoprecipitation Influence on protein activity in presence of IL6 0.25 µM Kms.11 Homo sapiens
AZD1480 Immunoprecipitation Influence on protein activity in presence of IL6 0.50 µM Kms.11 Homo sapiens
AZD1480 Immunoprecipitation Influence on protein activity in presence of IL6 1.00 µM Kms.11 Homo sapiens
AZD1480 Western Blot Influence on protein activity in presence of IL6 0.50 µM U266 Homo sapiens p-STAT3 (Y705)
AZD1480 Western Blot Influence on protein activity in presence of IL6 1.00 µM U266 Homo sapiens p-STAT3 (Y705)
AZD1480 Western Blot Influence on protein activity in presence of IL6 2.00 µM U266 Homo sapiens p-STAT3 (Y705)
AZD1480 Western Blot Influence on protein activity in presence of IL6 0.50 µM Kms.11 Homo sapiens p-STAT3 (Y705)
AZD1480 Western Blot Influence on protein activity in presence of IL6 1.00 µM Kms.11 Homo sapiens p-STAT3 (Y705)
AZD1480 Western Blot Influence on protein activity in presence of IL6 2.00 µM Kms.11 Homo sapiens p-STAT3 (Y705)
AZD1480 Western Blot Influence on protein activity in presence of IL6 0.50 µM U266 Homo sapiens STAT3
AZD1480 Western Blot Influence on protein activity in presence of IL6 1.00 µM U266 Homo sapiens STAT3
AZD1480 Western Blot Influence on protein activity in presence of IL6 2.00 µM U266 Homo sapiens STAT3
AZD1480 Western Blot Influence on protein activity in presence of IL6 0.50 µM Kms.11 Homo sapiens STAT3
AZD1480 Western Blot Influence on protein activity in presence of IL6 1.00 µM Kms.11 Homo sapiens STAT3
AZD1480 Western Blot Influence on protein activity in presence of IL6 2.00 µM Kms.11 Homo sapiens STAT3
AZD1480 Western Blot Influence on protein activity in presence of IL6 0.50 µM U266 Homo sapiens
AZD1480 Western Blot Influence on protein activity in presence of IL6 1.00 µM U266 Homo sapiens
AZD1480 Western Blot Influence on protein activity in presence of IL6 2.00 µM U266 Homo sapiens
AZD1480 Western Blot Influence on protein activity in presence of IL6 0.50 µM Kms.11 Homo sapiens
AZD1480 Western Blot Influence on protein activity in presence of IL6 1.00 µM Kms.11 Homo sapiens
AZD1480 Western Blot Influence on protein activity in presence of IL6 2.00 µM Kms.11 Homo sapiens
AZD1480 Western Blot Influence on protein activity in presence of IL6 0.50 µM U266 Homo sapiens
AZD1480 Western Blot Influence on protein activity in presence of IL6 1.00 µM U266 Homo sapiens
AZD1480 Western Blot Influence on protein activity in presence of IL6 2.00 µM U266 Homo sapiens
AZD1480 Western Blot Influence on protein activity in presence of IL6 0.50 µM Kms.11 Homo sapiens
AZD1480 Western Blot Influence on protein activity in presence of IL6 1.00 µM Kms.11 Homo sapiens
AZD1480 Western Blot Influence on protein activity in presence of IL6 2.00 µM Kms.11 Homo sapiens
AZD1480 Western Blot Influence on STAT3 downstream target genes in presence of IL-6 0.25 µM U266 Homo sapiens
AZD1480 Western Blot Influence on STAT3 downstream target genes in presence of IL-6 0.50 µM U266 Homo sapiens
AZD1480 Western Blot Influence on STAT3 downstream target genes in presence of IL-6 1.00 µM U266 Homo sapiens
AZD1480 Western Blot Influence on STAT3 downstream target genes in presence of IL-6 0.25 µM U266 Homo sapiens
AZD1480 Western Blot Influence on STAT3 downstream target genes in presence of IL-6 0.50 µM U266 Homo sapiens
AZD1480 Western Blot Influence on STAT3 downstream target genes in presence of IL-6 1.00 µM U266 Homo sapiens
AZD1480 Western Blot Influence on STAT3 downstream target genes in presence of IL-6 0.25 µM U266 Homo sapiens
AZD1480 Western Blot Influence on STAT3 downstream target genes in presence of IL-6 0.50 µM U266 Homo sapiens
AZD1480 Western Blot Influence on STAT3 downstream target genes in presence of IL-6 1.00 µM U266 Homo sapiens
AZD1480 Western Blot Influence on STAT3 downstream target genes in presence of IL-6 0.25 µM U266 Homo sapiens
AZD1480 Western Blot Influence on STAT3 downstream target genes in presence of IL-6 0.50 µM U266 Homo sapiens
AZD1480 Western Blot Influence on STAT3 downstream target genes in presence of IL-6 1.00 µM U266 Homo sapiens
AZD1480 Western Blot Influence on STAT3 downstream target genes in presence of IL-6 0.25 µM Kms.11 Homo sapiens
AZD1480 Western Blot Influence on STAT3 downstream target genes in presence of IL-6 0.50 µM Kms.11 Homo sapiens
AZD1480 Western Blot Influence on STAT3 downstream target genes in presence of IL-6 1.00 µM Kms.11 Homo sapiens
AZD1480 Western Blot Influence on STAT3 downstream target genes in presence of IL-6 0.25 µM Kms.11 Homo sapiens
AZD1480 Western Blot Influence on STAT3 downstream target genes in presence of IL-6 0.50 µM Kms.11 Homo sapiens
AZD1480 Western Blot Influence on STAT3 downstream target genes in presence of IL-6 1.00 µM Kms.11 Homo sapiens
AZD1480 Western Blot Influence on STAT3 downstream target genes in presence of IL-6 0.25 µM U266 Homo sapiens
AZD1480 Western Blot Influence on STAT3 downstream target genes in presence of IL-6 0.50 µM U266 Homo sapiens
AZD1480 Western Blot Influence on STAT3 downstream target genes in presence of IL-6 1.00 µM U266 Homo sapiens
AZD1480 MTS Assay Influence on cell viability 0.50 µM Kms.11 Homo sapiens
AZD1480 MTS Assay Influence on cell viability 1.00 µM Kms.11 Homo sapiens
AZD1480 MTS Assay Influence on cell viability 2.00 µM Kms.11 Homo sapiens
AZD1480 MTS Assay Influence on cell viability 0.50 µM HS-5 Homo sapiens
AZD1480 MTS Assay Influence on cell viability 1.00 µM HS-5 Homo sapiens
AZD1480 MTS Assay Influence on cell viability 2.00 µM HS-5 Homo sapiens
AZD1480 Cell-free kinase assay; Western Blot Influence on kinase activity 0.10 µM Homo sapiens p-STAT1
AZD1480 Cell-free kinase assay; Western Blot Influence on kinase activity 0.20 µM Homo sapiens p-STAT1
AZD1480 Cell-free kinase assay; Western Blot Influence on kinase activity 0.50 µM Homo sapiens p-STAT1
AZD1480 Cell-free kinase assay; Western Blot Influence on kinase activity 1.00 µM Homo sapiens p-STAT1
AZD1480 Cell-free kinase assay; Western Blot Influence on kinase activity 5.00 µM Homo sapiens p-STAT1
AZD1480 Cell-free kinase assay; Western Blot Influence on kinase activity 10.00 µM Homo sapiens p-STAT1
AZD1480 Cell-free kinase assay; Western Blot Influence on kinase activity 0.10 µM Homo sapiens STAT1
AZD1480 Cell-free kinase assay; Western Blot Influence on kinase activity 0.20 µM Homo sapiens STAT1
AZD1480 Cell-free kinase assay; Western Blot Influence on kinase activity 0.50 µM Homo sapiens STAT1
AZD1480 Cell-free kinase assay; Western Blot Influence on kinase activity 1.00 µM Homo sapiens STAT1
AZD1480 Cell-free kinase assay; Western Blot Influence on kinase activity 5.00 µM Homo sapiens STAT1
AZD1480 Cell-free kinase assay; Western Blot Influence on kinase activity 10.00 µM Homo sapiens STAT1
AZD1480 Cell-free kinase assay; Western Blot Influence on kinase activity 0.20 µM Homo sapiens
AZD1480 Cell-free kinase assay; Western Blot Influence on kinase activity 0.50 µM Homo sapiens
AZD1480 Cell-free kinase assay; Western Blot Influence on kinase activity 1.00 µM Homo sapiens
AZD1480 Cell-free kinase assay; Western Blot Influence on kinase activity 5.00 µM Homo sapiens
AZD1480 Cell-free kinase assay; Western Blot Influence on kinase activity 10.00 µM Homo sapiens
AZD1480 Cell-free kinase assay; Western Blot Influence on kinase activity 0.20 µM Homo sapiens
AZD1480 Cell-free kinase assay; Western Blot Influence on kinase activity 0.50 µM Homo sapiens
AZD1480 Cell-free kinase assay; Western Blot Influence on kinase activity 1.00 µM Homo sapiens
AZD1480 Cell-free kinase assay; Western Blot Influence on kinase activity 5.00 µM Homo sapiens
AZD1480 Cell-free kinase assay; Western Blot Influence on kinase activity 10.00 µM Homo sapiens
AZD1480 Tumor volume Influence on cell proliferation in tumor tissue 30.00 mg/kg Kms.11 (xenograft) Mus musculus NOD/SCID IL2Rγ-null mice
AZD1480 Western Blot Influence on protein activity in tumor tissue 30.00 mg/kg Kms.11 (xenograft) Mus musculus NOD/SCID IL2Rγ-null mice p-STAT3 (Y705)
AZD1480 Western Blot Influence on protein activity in tumor tissue 30.00 mg/kg Kms.11 (xenograft) Mus musculus NOD/SCID IL2Rγ-null mice STAT3
AZD1480 Western Blot Influence on protein activity in tumor tissue 30.00 mg/kg Kms.11 (xenograft) Mus musculus NOD/SCID IL2Rγ-null mice
AZD1480 Western Blot Influence on protein activity in tumor tissue 30.00 mg/kg Kms.11 (xenograft) Mus musculus NOD/SCID IL2Rγ-null mice
AZD1480 Western Blot Influence on protein activity in tumor tissue 30.00 mg/kg Kms.11 (xenograft) Mus musculus NOD/SCID IL2Rγ-null mice
AZD1480 Western Blot Influence on protein activity in tumor tissue 30.00 mg/kg Kms.11 (xenograft) Mus musculus NOD/SCID IL2Rγ-null mice
AZD1480 Immunoprecipitation Influence on protein activity in tumor tissue 30.00 mg/kg Kms.11 (xenograft) Mus musculus NOD/SCID IL2Rγ-null mice
AZD1480 Immunoprecipitation Influence on protein activity in tumor tissue 30.00 mg/kg Kms.11 (xenograft) Mus musculus NOD/SCID IL2Rγ-null mice
AZD1480 Immunoprecipitation Influence on protein activity in tumor tissue 30.00 mg/kg Kms.11 (xenograft) Mus musculus NOD/SCID IL2Rγ-null mice
AZD1480 Immunoprecipitation Influence on protein activity in tumor tissue 30.00 mg/kg Kms.11 (xenograft) Mus musculus NOD/SCID IL2Rγ-null mice
AZD1480 Western Blot Influence on protein activity 1.00 µM U251-MG Homo sapiens p-STAT3 (Y705)
AZD1480 Western Blot Influence on protein activity 1.00 µM U87-MG Homo sapiens p-STAT3 (Y705)
AZD1480 Western Blot Influence on protein activity 1.00 µM U251-MG Homo sapiens STAT3
AZD1480 Western Blot Influence on protein activity 1.00 µM U87-MG Homo sapiens STAT3
AZD1480 Western Blot Influence on protein activity 1.00 µM U251-MG Homo sapiens
AZD1480 Western Blot Influence on protein activity 1.00 µM U87-MG Homo sapiens
AZD1480 Western Blot Influence on protein activity 1.00 µM U251-MG Homo sapiens
AZD1480 Western Blot Influence on protein activity 1.00 µM U87-MG Homo sapiens
AZD1480 Western Blot Influence on protein activity 1.00 µM U251-MG Homo sapiens
AZD1480 Western Blot Influence on protein activity 1.00 µM U87-MG Homo sapiens
AZD1480 Western Blot Influence on protein activity 1.00 µM 4C8 Homo sapiens p-STAT3 (Y705)
AZD1480 Western Blot Influence on protein activity 1.00 µM 4C8 Homo sapiens STAT3
AZD1480 WST-1 Cell Proliferation Assay Influence on cell proliferation 1.00 µM U251-MG Homo sapiens
AZD1480 WST-1 Cell Proliferation Assay Influence on cell proliferation 10.00 µM U251-MG Homo sapiens
AZD1480 WST-1 Cell Proliferation Assay Influence on cell proliferation 1.00 µM 4C8 Homo sapiens
AZD1480 WST-1 Cell Proliferation Assay Influence on cell proliferation 10.00 µM 4C8 Homo sapiens
AZD1480 WST-1 Cell Proliferation Assay Influence on cell proliferation 1.00 µM Murine Primary Astrocytes Mus musculus
AZD1480 WST-1 Cell Proliferation Assay Influence on cell proliferation 10.00 µM Murine Primary Astrocytes Mus musculus
AZD1480 Flow cytometry- annexin V staining Cell Apoptosis Analysis 1.00 µM U251-MG Homo sapiens
AZD1480 Flow cytometry- annexin V staining Cell Apoptosis Analysis 10.00 µM U251-MG Homo sapiens
AZD1480 Western Blot Cell Apoptosis Analysis 1.00 µM U251-MG Homo sapiens
AZD1480 Western Blot Cell Apoptosis Analysis 10.00 µM U251-MG Homo sapiens
AZD1480 Western Blot Cell Apoptosis Analysis 1.00 µM U251-MG Homo sapiens
AZD1480 Western Blot Cell Apoptosis Analysis 10.00 µM U251-MG Homo sapiens
AZD1480 Soft Agar Growth Assay Influence on cell motility 1.00 µM U251-MG Homo sapiens
AZD1480 Soft Agar Growth Assay Influence on cell motility 10.00 µM U251-MG Homo sapiens
AZD1480 Western Blot Influence on protein activity in presence of OSM 0.10 µM U251-MG Homo sapiens p-STAT3 (Y705)
AZD1480 Western Blot Influence on protein activity in presence of OSM 0.50 µM U251-MG Homo sapiens p-STAT3 (Y705)
AZD1480 Western Blot Influence on protein activity in presence of OSM 1.00 µM U251-MG Homo sapiens p-STAT3 (Y705)
AZD1480 Western Blot Influence on protein activity in presence of OSM 10.00 µM U251-MG Homo sapiens p-STAT3 (Y705)
AZD1480 Western Blot Influence on protein activity in presence of OSM 0.10 µM U87-MG Homo sapiens p-STAT3 (Y705)
AZD1480 Western Blot Influence on protein activity in presence of OSM 0.50 µM U87-MG Homo sapiens p-STAT3 (Y705)
AZD1480 Western Blot Influence on protein activity in presence of OSM 1.00 µM U87-MG Homo sapiens p-STAT3 (Y705)
AZD1480 Western Blot Influence on protein activity in presence of OSM 10.00 µM U87-MG Homo sapiens p-STAT3 (Y705)
AZD1480 Western Blot Influence on protein activity in presence of OSM 0.10 µM 4C8 Homo sapiens p-STAT3 (Y705)
AZD1480 Western Blot Influence on protein activity in presence of OSM 0.50 µM 4C8 Homo sapiens p-STAT3 (Y705)
AZD1480 Western Blot Influence on protein activity in presence of OSM 1.00 µM 4C8 Homo sapiens p-STAT3 (Y705)
AZD1480 Western Blot Influence on protein activity in presence of OSM 10.00 µM 4C8 Homo sapiens p-STAT3 (Y705)
AZD1480 Western Blot Influence on protein activity in presence of OSM 0.10 µM U251-MG Homo sapiens STAT3
AZD1480 Western Blot Influence on protein activity in presence of OSM 0.50 µM U251-MG Homo sapiens STAT3
AZD1480 Western Blot Influence on protein activity in presence of OSM 1.00 µM U251-MG Homo sapiens STAT3
AZD1480 Western Blot Influence on protein activity in presence of OSM 10.00 µM U251-MG Homo sapiens STAT3
AZD1480 Western Blot Influence on protein activity in presence of OSM 0.10 µM U87-MG Homo sapiens STAT3
AZD1480 Western Blot Influence on protein activity in presence of OSM 0.50 µM U87-MG Homo sapiens STAT3
AZD1480 Western Blot Influence on protein activity in presence of OSM 1.00 µM U87-MG Homo sapiens STAT3
AZD1480 Western Blot Influence on protein activity in presence of OSM 10.00 µM U87-MG Homo sapiens STAT3
AZD1480 Western Blot Influence on protein activity in presence of OSM 0.10 µM 4C8 Homo sapiens STAT3
AZD1480 Western Blot Influence on protein activity in presence of OSM 0.50 µM 4C8 Homo sapiens STAT3
AZD1480 Western Blot Influence on protein activity in presence of OSM 1.00 µM 4C8 Homo sapiens STAT3
AZD1480 Western Blot Influence on protein activity in presence of OSM 10.00 µM 4C8 Homo sapiens STAT3
AZD1480 Western Blot Influence on protein activity in presence of OSM 0.10 µM U251-MG Homo sapiens
AZD1480 0.50 µM U251-MG Homo sapiens
AZD1480 Western Blot Influence on protein activity in presence of OSM 1.00 µM U251-MG Homo sapiens
AZD1480 Western Blot Influence on protein activity in presence of OSM 10.00 µM U251-MG Homo sapiens
AZD1480 Western Blot Influence on protein activity in presence of OSM 0.10 µM U87-MG Homo sapiens
AZD1480 Western Blot Influence on protein activity in presence of OSM 0.50 µM U87-MG Homo sapiens
AZD1480 Western Blot Influence on protein activity in presence of OSM 1.00 µM U87-MG Homo sapiens
AZD1480 Western Blot Influence on protein activity in presence of OSM 10.00 µM U87-MG Homo sapiens
AZD1480 Western Blot Influence on protein activity in presence of OSM 0.10 µM 4C8 Homo sapiens
AZD1480 Western Blot Influence on protein activity in presence of OSM 0.50 µM 4C8 Homo sapiens
AZD1480 Western Blot Influence on protein activity in presence of OSM 1.00 µM 4C8 Homo sapiens
AZD1480 Western Blot Influence on protein activity in presence of OSM 10.00 µM 4C8 Homo sapiens
AZD1480 Western Blot Influence on protein activity in presence of OSM 0.50 µM U251-MG Homo sapiens
AZD1480 Western Blot Influence on protein activity in presence of OSM 1.00 µM U251-MG Homo sapiens
AZD1480 Western Blot Influence on protein activity in presence of OSM 10.00 µM U251-MG Homo sapiens
AZD1480 Western Blot Influence on protein activity in presence of OSM 0.10 µM U87-MG Homo sapiens
AZD1480 Western Blot Influence on protein activity in presence of OSM 0.50 µM U87-MG Homo sapiens
AZD1480 Western Blot Influence on protein activity in presence of OSM 1.00 µM U87-MG Homo sapiens
AZD1480 Western Blot Influence on protein activity in presence of OSM 10.00 µM U87-MG Homo sapiens
AZD1480 Western Blot Influence on protein activity in presence of OSM 0.10 µM 4C8 Homo sapiens
AZD1480 Western Blot Influence on protein activity in presence of OSM 0.50 µM 4C8 Homo sapiens
AZD1480 Western Blot Influence on protein activity in presence of OSM 1.00 µM 4C8 Homo sapiens
AZD1480 Western Blot Influence on protein activity in presence of OSM 10.00 µM 4C8 Homo sapiens
AZD1480 Western Blot Influence on protein activity in presence of OSM 0.10 µM U251-MG Homo sapiens
AZD1480 Western Blot Influence on protein activity in presence of OSM 0.50 µM U251-MG Homo sapiens
AZD1480 Western Blot Influence on protein activity in presence of OSM 1.00 µM U251-MG Homo sapiens
AZD1480 Western Blot Influence on protein activity in presence of OSM 10.00 µM U251-MG Homo sapiens
AZD1480 Western Blot Influence on protein activity in presence of OSM 0.10 µM U251-MG Homo sapiens
AZD1480 Western Blot Influence on protein activity in presence of OSM 0.50 µM U251-MG Homo sapiens
AZD1480 Western Blot Influence on protein activity in presence of OSM 1.00 µM U251-MG Homo sapiens
AZD1480 Western Blot Influence on protein activity in presence of OSM 10.00 µM U251-MG Homo sapiens
AZD1480 Western Blot Influence on protein activity in presence of OSM 0.10 µM U87-MG Homo sapiens
AZD1480 Western Blot Influence on protein activity in presence of OSM 0.50 µM U87-MG Homo sapiens
AZD1480 Western Blot Influence on protein activity in presence of OSM 1.00 µM U87-MG Homo sapiens
AZD1480 Western Blot Influence on protein activity in presence of OSM 10.00 µM U87-MG Homo sapiens
AZD1480 Western Blot Influence on protein activity in presence of OSM 0.10 µM 4C8 Homo sapiens
AZD1480 Western Blot Influence on protein activity in presence of OSM 0.50 µM 4C8 Homo sapiens
AZD1480 Western Blot Influence on protein activity in presence of OSM 1.00 µM 4C8 Homo sapiens
AZD1480 Western Blot Influence on protein activity in presence of OSM 10.00 µM 4C8 Homo sapiens
AZD1480 Western Blot Influence on protein activity in presence of OSM 0.10 µM U251-MG Homo sapiens
AZD1480 Western Blot Influence on protein activity in presence of OSM 0.50 µM U251-MG Homo sapiens
AZD1480 Western Blot Influence on protein activity in presence of OSM 1.00 µM U251-MG Homo sapiens
AZD1480 Western Blot Influence on protein activity in presence of OSM 10.00 µM U251-MG Homo sapiens
AZD1480 RT-qPCR Influence on downstream gene transcription 1.00 µM U251-MG Homo sapiens
AZD1480 RT-qPCR Influence on downstream gene transcription 1.00 µM U87-MG Homo sapiens
AZD1480 RT-qPCR Influence on downstream gene transcription 1.00 µM 4C8 Homo sapiens
AZD1480 RT-qPCR Influence on downstream gene transcription 1.00 µM U251-MG Homo sapiens
AZD1480 RT-qPCR Influence on downstream gene transcription 1.00 µM U87-MG Homo sapiens
AZD1480 RT-qPCR Influence on downstream gene transcription 1.00 µM 4C8 Homo sapiens
AZD1480 RT-qPCR Influence on downstream gene transcription 1.00 µM U251-MG Homo sapiens
AZD1480 RT-qPCR Influence on downstream gene transcription 1.00 µM U87-MG Homo sapiens
AZD1480 RT-qPCR Influence on downstream gene transcription 1.00 µM 4C8 Homo sapiens
AZD1480 Western Blot Influence on protein activity in tumor tissue in presence of OSM 0.10 µM Xenograft X1066 Mus musculus athymic nude mice p-STAT3 (Y705)
AZD1480 Western Blot Influence on protein activity in tumor tissue in presence of OSM 0.50 µM Xenograft X1066 Mus musculus athymic nude mice p-STAT3 (Y705)
AZD1480 Western Blot Influence on protein activity in tumor tissue in presence of OSM 1.00 µM Xenograft X1066 Mus musculus athymic nude mice p-STAT3 (Y705)
AZD1480 Western Blot Influence on protein activity in tumor tissue in presence of OSM 10.00 µM Xenograft X1066 Mus musculus athymic nude mice p-STAT3 (Y705)
AZD1480 Western Blot Influence on protein activity in tumor tissue in presence of OSM 0.10 µM Xenograft X1066 Mus musculus athymic nude mice STAT3
AZD1480 Western Blot Influence on protein activity in tumor tissue in presence of OSM 0.50 µM Xenograft X1066 Mus musculus athymic nude mice STAT3
AZD1480 Western Blot Influence on protein activity in tumor tissue in presence of OSM 1.00 µM Xenograft X1066 Mus musculus athymic nude mice STAT3
AZD1480 Western Blot Influence on protein activity in tumor tissue in presence of OSM 10.00 µM Xenograft X1066 Mus musculus athymic nude mice STAT3
AZD1480 Western Blot Influence on protein activity in tumor tissue in presence of OSM 0.10 µM Xenograft X1066 Mus musculus athymic nude mice
AZD1480 Western Blot Influence on protein activity in tumor tissue in presence of OSM 0.50 µM Xenograft X1066 Mus musculus athymic nude mice
AZD1480 Western Blot Influence on protein activity in tumor tissue in presence of OSM 1.00 µM Xenograft X1066 Mus musculus athymic nude mice
AZD1480 Western Blot Influence on protein activity in tumor tissue in presence of OSM 10.00 µM Xenograft X1066 Mus musculus athymic nude mice
AZD1480 Western Blot Influenc