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Experiments

Compound Investigated event Experiment type Concentration Cell line Organism Animal model Stat protein Details
Niclosamide Influence on protein activity in presence of IL-6 Western Blot 50.00 µM MM1.S Homo sapiens STAT3
Niclosamide Influence on protein activity in presence of pervanadate Western Blot 50.00 µM MM1.S Homo sapiens p-STAT3(Tyr705)
Niclosamide Influence on protein activity in presence of pervanadate Western Blot 50.00 µM MM1.S Homo sapiens STAT3
Niclosamide Influence on cell apoptosis Flow cytometry- annexin V staining 30.00 µM U266 Homo sapiens
Niclosamide Influence on cell apoptosis Flow cytometry- annexin V staining 50.00 µM U266 Homo sapiens
Niclosamide Influence on cell apoptosis TUNEL assay 30.00 µM U266 Homo sapiens
Niclosamide Influence on cell apoptosis TUNEL assay 50.00 µM U266 Homo sapiens
Niclosamide Influence on cell apoptosis Live/Dead assay 30.00 µM U266 Homo sapiens
Niclosamide Influence on cell apoptosis Live/Dead assay 50.00 µM U266 Homo sapiens
Niclosamide Influence on cell proliferation MTT 30.00 µM MM1.S Homo sapiens
Niclosamide Influence on cell proliferation MTT 50.00 µM MM1.S Homo sapiens
Niclosamide Influence on cell proliferation MTT 30.00 µM U266 Homo sapiens
Niclosamide Influence on cell proliferation MTT 50.00 µM U266 Homo sapiens
Niclosamide Influence on protein activity Western Blot 30.00 µM U266 Homo sapiens
Niclosamide Influence on protein activity Western Blot 50.00 µM U266 Homo sapiens
Niclosamide Influence on protein activity Western Blot 30.00 µM U266 Homo sapiens
Niclosamide Influence on protein activity Western Blot 50.00 µM U266 Homo sapiens
Niclosamide Influence on protein activity Western Blot 30.00 µM U266 Homo sapiens
Niclosamide Influence on protein activity Western Blot 50.00 µM U266 Homo sapiens
Niclosamide Influence on protein activity Western Blot 30.00 µM U266 Homo sapiens
Niclosamide Influence on protein activity Western Blot 50.00 µM U266 Homo sapiens
Niclosamide Influence on protein activity Western Blot 30.00 µM U266 Homo sapiens
Niclosamide Influence on protein activity Western Blot 50.00 µM U266 Homo sapiens
Niclosamide Influence on protein activity Western Blot 30.00 µM U266 Homo sapiens
Niclosamide Influence on protein activity Western Blot 50.00 µM U266 Homo sapiens
Niclosamide Influence on protein activity Western Blot 30.00 µM U266 Homo sapiens
Niclosamide Influence on protein activity Western Blot 50.00 µM U266 Homo sapiens
Niclosamide Influence on protein activity Western Blot 30.00 µM U266 Homo sapiens
Niclosamide Influence on protein activity Western Blot 50.00 µM U266 Homo sapiens
Niclosamide Influence on protein activity Western Blot 30.00 µM U266 Homo sapiens
Niclosamide Influence on protein activity Western Blot 50.00 µM U266 Homo sapiens
Niclosamide Influence on target gene expression RT-qPCR 30.00 µM U266 Homo sapiens
Niclosamide Influence on target gene expression RT-qPCR 50.00 µM U266 Homo sapiens
Niclosamide Influence on target gene expression RT-qPCR 30.00 µM U266 Homo sapiens
Niclosamide Influence on target gene expression RT-qPCR 50.00 µM U266 Homo sapiens
Niclosamide Influence on target gene expression RT-qPCR 30.00 µM U266 Homo sapiens
Niclosamide Influence on target gene expression RT-qPCR 50.00 µM U266 Homo sapiens
Niclosamide Influence on protein activity Luciferase reporter assay N/A N/A Hela Homo sapiens
Niclosamide Influence on protein activity Western Blot 0.10 µM Hela Homo sapiens p-STAT3(Tyr705)
Niclosamide Influence on protein activity Western Blot 0.20 µM Hela Homo sapiens p-STAT3(Tyr705)
Niclosamide Influence on protein activity Western Blot 0.50 µM Hela Homo sapiens p-STAT3(Tyr705)
Niclosamide Influence on protein activity Western Blot 1.00 µM Hela Homo sapiens p-STAT3(Tyr705)
Niclosamide Influence on protein activity Western Blot 2.00 µM Hela Homo sapiens p-STAT3(Tyr705)
Niclosamide Influence on protein activity Western Blot 0.10 µM Hela Homo sapiens p-STAT3(Ser727)
Niclosamide Influence on protein activity Western Blot 0.20 µM Hela Homo sapiens p-STAT3(Ser727)
Niclosamide Influence on protein activity Western Blot 0.50 µM Hela Homo sapiens p-STAT3(Ser727)
Niclosamide Influence on protein activity Western Blot 1.00 µM Hela Homo sapiens p-STAT3(Ser727)
Niclosamide Influence on protein activity Western Blot 2.00 µM Hela Homo sapiens p-STAT3(Ser727)
Niclosamide Influence on protein activity Western Blot 0.10 µM Hela Homo sapiens STAT3
Niclosamide Influence on protein activity Western Blot 0.20 µM Hela Homo sapiens STAT3