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Experiments

Compound Investigated event Experiment type Concentration Cell line Organism Animal model Stat protein Details
Toosendanin Influence on protein activity Western Blot 100.00 nM SKOV3 Homo sapiens
Toosendanin Influence on protein activity Western Blot 200.00 nM SKOV3 Homo sapiens
Toosendanin Influence on protein activity Western Blot 100.00 nM MDA-MB-231 Homo sapiens p-STAT3
Toosendanin Influence on protein activity Western Blot 200.00 nM MDA-MB-231 Homo sapiens p-STAT3
Toosendanin Influence on protein activity Western Blot 100.00 nM MDA-MB-231 Homo sapiens STAT3
Toosendanin Influence on protein activity Western Blot 200.00 nM MDA-MB-231 Homo sapiens STAT3
Toosendanin Influence on protein activity Western Blot 100.00 nM MDA-MB-231 Homo sapiens
Toosendanin Influence on protein activity Western Blot 200.00 nM MDA-MB-231 Homo sapiens
Toosendanin Influence on protein activity Western Blot 100.00 nM DU145 Homo sapiens p-STAT3
Toosendanin Influence on protein activity Western Blot 200.00 nM DU145 Homo sapiens p-STAT3
Toosendanin Influence on protein activity Western Blot 100.00 nM DU145 Homo sapiens STAT3
Toosendanin Influence on protein activity Western Blot 200.00 nM DU145 Homo sapiens STAT3
Toosendanin Influence on protein activity Western Blot 100.00 nM DU145 Homo sapiens
Toosendanin Influence on protein activity Western Blot 200.00 nM DU145 Homo sapiens
Toosendanin Influence on protein activity Western Blot 100.00 nM Hela Homo sapiens p-STAT3
Toosendanin Influence on protein activity Western Blot 200.00 nM Hela Homo sapiens p-STAT3
Toosendanin Influence on protein activity Western Blot 100.00 nM Hela Homo sapiens STAT3
Toosendanin Influence on protein activity Western Blot 200.00 nM Hela Homo sapiens STAT3
Toosendanin Influence on protein activity Western Blot 100.00 nM Hela Homo sapiens
Toosendanin Influence on protein activity Western Blot 200.00 nM Hela Homo sapiens
Toosendanin Influence on protein activity Western Blot 100.00 nM SW-1990 Homo sapiens p-STAT3
Toosendanin Influence on protein activity Western Blot 200.00 nM SW-1990 Homo sapiens p-STAT3
Toosendanin Influence on protein activity Western Blot 100.00 nM SW-1990 Homo sapiens STAT3
Toosendanin Influence on protein activity Western Blot 200.00 nM SW-1990 Homo sapiens STAT3
Toosendanin Influence on protein activity Western Blot 100.00 nM SW-1990 Homo sapiens
Toosendanin Influence on protein activity Western Blot 200.00 nM SW-1990 Homo sapiens
Plumbagin Influence on cell apoptosis Flow cytometry- annexin V binding and propidium iodide staining 5.00 µM DU145 Homo sapiens
Plumbagin Influence on cell apoptosis Flow cytometry- annexin V binding and propidium iodide staining 10.00 µM DU145 Homo sapiens
Plumbagin Influence on cell apoptosis Flow cytometry- annexin V binding and propidium iodide staining 15.00 µM DU145 Homo sapiens
Plumbagin Influence on cell apoptosis Flow cytometry- annexin V binding and propidium iodide staining 5.00 µM RWPE-1 Homo sapiens
Plumbagin Influence on cell apoptosis Flow cytometry- annexin V binding and propidium iodide staining 10.00 µM RWPE-1 Homo sapiens
Plumbagin Influence on cell apoptosis Flow cytometry- annexin V binding and propidium iodide staining 15.00 µM RWPE-1 Homo sapiens
Plumbagin Influence on cell apoptosis Flow cytometry- annexin V binding and propidium iodide staining 5.00 µM CWR22Rv1 Homo sapiens
Plumbagin Influence on cell apoptosis Flow cytometry- annexin V binding and propidium iodide staining 10.00 µM CWR22Rv1 Homo sapiens
Plumbagin Influence on cell apoptosis Flow cytometry- annexin V binding and propidium iodide staining 15.00 µM CWR22Rv1 Homo sapiens
Plumbagin Influence on cell apoptosis Flow cytometry- annexin V binding and propidium iodide staining 5.00 µM LNCaP Homo sapiens
Plumbagin Influence on cell apoptosis Flow cytometry- annexin V binding and propidium iodide staining 10.00 µM LNCaP Homo sapiens
Plumbagin Influence on cell apoptosis Flow cytometry- annexin V binding and propidium iodide staining 15.00 µM LNCaP Homo sapiens
Plumbagin Influence on cell motility Invasion assay 5.00 µM DU145 Homo sapiens
Plumbagin Influence on cell motility Invasion assay 20.00 µM DU145 Homo sapiens
Plumbagin Influence on cell motility Invasion assay 5.00 µM CWR22Rv1 Homo sapiens
Plumbagin Influence on cell motility Invasion assay 20.00 µM CWR22Rv1 Homo sapiens
Plumbagin Influence on cell motility Invasion assay 5.00 µM PC-3 Homo sapiens
Plumbagin Influence on cell motility Invasion assay 20.00 µM PC-3 Homo sapiens
Plumbagin Influence on cell proliferation in tumor tissue Tumor weight 2.00 mg/kg DU145(xenograft) Mus musculus athymic nude mice
Plumbagin Influence on cell proliferation in tumor tissue Tumor volume 2.00 mg/kg DU145(xenograft) Mus musculus athymic nude mice
Plumbagin Influence on cell proliferation in tumor tissue Immunohistochemistry 2.00 mg/kg DU145(xenograft) Mus musculus athymic nude mice STAT3
Plumbagin Influence on cell proliferation in tumor tissue Immunohistochemistry 2.00 mg/kg DU145(xenograft) Mus musculus athymic nude mice
Plumbagin Influence on cell proliferation in tumor tissue Immunohistochemistry 2.00 mg/kg DU145(xenograft) Mus musculus athymic nude mice
Plumbagin Influence on protein activity in tumor tissue Western Blot 2.00 mg/kg DU145(xenograft) Mus musculus athymic nude mice