Sorafenib |
Influence on cell cycle |
Western Blot |
3.00 µM |
U87 |
Homo sapiens |
|
|
|
Sorafenib |
Influence on protein activity |
Western Blot |
3.00 µM |
U87 |
Homo sapiens |
|
|
|
Sorafenib |
Influence on protein activity |
Western Blot |
7.00 µM |
U87 |
Homo sapiens |
|
|
|
Sorafenib |
Influence on protein activity |
Western Blot |
15.00 µM |
U87 |
Homo sapiens |
|
|
|
Sorafenib |
Influence on protein activity |
Western Blot |
3.00 µM |
U87 |
Homo sapiens |
|
|
|
Sorafenib |
Influence on protein activity |
Western Blot |
7.00 µM |
U87 |
Homo sapiens |
|
|
|
Sorafenib |
Influence on protein activity |
Western Blot |
15.00 µM |
U87 |
Homo sapiens |
|
|
|
Sorafenib |
Influence on protein activity |
Western Blot |
3.00 µM |
U87 |
Homo sapiens |
|
p-STAT3(Y705) |
|
Sorafenib |
Influence on protein activity |
Western Blot |
7.00 µM |
U87 |
Homo sapiens |
|
p-STAT3(Y705) |
|
Sorafenib |
Influence on protein activity |
Western Blot |
15.00 µM |
U87 |
Homo sapiens |
|
p-STAT3(Y705) |
|
Sorafenib |
Influence on protein activity |
Western Blot |
3.00 µM |
U87 |
Homo sapiens |
|
STAT3 |
|
Sorafenib |
Influence on protein activity |
Western Blot |
7.00 µM |
U87 |
Homo sapiens |
|
STAT3 |
|
Sorafenib |
Influence on protein activity |
Western Blot |
15.00 µM |
U87 |
Homo sapiens |
|
STAT3 |
|
Sorafenib |
Influence on protein activity |
Western Blot |
3.00 µM |
U87 |
Homo sapiens |
|
|
|
Sorafenib |
Influence on protein activity |
Western Blot |
7.00 µM |
U87 |
Homo sapiens |
|
|
|
Sorafenib |
Influence on protein activity |
Western Blot |
15.00 µM |
U87 |
Homo sapiens |
|
|
|
Sorafenib |
Influence on protein activity |
Western Blot |
3.00 µM |
U87 |
Homo sapiens |
|
|
|
Sorafenib |
Influence on protein activity |
Western Blot |
7.00 µM |
U87 |
Homo sapiens |
|
|
|
Sorafenib |
Influence on protein activity |
Western Blot |
15.00 µM |
U87 |
Homo sapiens |
|
|
|
Sorafenib |
Influence on protein activity |
Western Blot |
3.00 µM |
U87 |
Homo sapiens |
|
|
|
Sorafenib |
Influence on protein activity |
Western Blot |
7.00 µM |
U87 |
Homo sapiens |
|
|
|
Sorafenib |
Influence on protein activity |
Western Blot |
15.00 µM |
U87 |
Homo sapiens |
|
|
|
Sorafenib |
Influence on protein activity |
Western Blot |
3.00 µM |
U87 |
Homo sapiens |
|
|
|
Sorafenib |
Influence on protein activity |
Western Blot |
7.00 µM |
U87 |
Homo sapiens |
|
|
|
Sorafenib |
Influence on protein activity |
Western Blot |
15.00 µM |
U87 |
Homo sapiens |
|
|
|
Sorafenib |
Influence on protein activity |
Western Blot |
3.00 µM |
U87 |
Homo sapiens |
|
|
|
Sorafenib |
Influence on protein activity |
Western Blot |
7.00 µM |
U87 |
Homo sapiens |
|
|
|
Sorafenib |
Influence on protein activity |
Western Blot |
15.00 µM |
U87 |
Homo sapiens |
|
|
|
Sorafenib |
Influence on protein activity |
Western Blot |
3.00 µM |
U87 |
Homo sapiens |
|
|
|
Sorafenib |
Influence on protein activity |
Western Blot |
7.00 µM |
U87 |
Homo sapiens |
|
|
|
Sorafenib |
Influence on protein activity |
Western Blot |
15.00 µM |
U87 |
Homo sapiens |
|
|
|
Sorafenib |
Influence on cell viability |
Trypan Blue staining |
N/A µM |
U87 |
Homo sapiens |
|
|
|
Sorafenib |
Influence on cell viability |
Trypan Blue staining |
N/A µM |
LN229 |
Homo sapiens |
|
|
|
Sorafenib |
Influence on cell viability in transfected cells |
Western Blot |
3.00 µM |
U87 |
Homo sapiens |
|
|
|
Sorafenib |
Influence on cell viability in transfected cells |
Western Blot |
7.00 µM |
U87 |
Homo sapiens |
|
|
|
Sorafenib |
Influence on cell viability in transfected cells |
Western Blot |
15.00 µM |
U87 |
Homo sapiens |
|
|
|
Sorafenib |
Influence on cell viability in transfected cells |
Western Blot |
3.00 µM |
U87 |
Homo sapiens |
|
|
|
Sorafenib |
Influence on cell viability in transfected cells |
Western Blot |
7.00 µM |
U87 |
Homo sapiens |
|
|
|
Sorafenib |
Influence on cell viability in transfected cells |
Western Blot |
15.00 µM |
U87 |
Homo sapiens |
|
|
|
Sorafenib |
Influence on cell viability in transfected cells |
Western Blot |
3.00 µM |
U87 |
Homo sapiens |
|
|
|
Sorafenib |
Influence on cell viability in transfected cells |
Western Blot |
7.00 µM |
U87 |
Homo sapiens |
|
|
|
Sorafenib |
Influence on cell viability in transfected cells |
Western Blot |
15.00 µM |
U87 |
Homo sapiens |
|
|
|
Sorafenib |
Influence on tumor growth |
Bioluminescence |
100.00 mg/kg |
U87-Luc |
Mus musculus |
NIH Nu/Nu |
|
|
Sorafenib |
Influence on tumor growth |
Percent survival |
100.00 mg/kg |
U87-Luc |
Mus musculus |
NIH Nu/Nu |
|
|
Sorafenib |
Influence on tumor growth |
Immunohistochemistry |
100.00 mg/kg |
U87-Luc |
Mus musculus |
NIH Nu/Nu |
|
|
Sorafenib |
Influence on tumor growth |
Immunohistochemistry |
100.00 mg/kg |
U87-Luc |
Mus musculus |
NIH Nu/Nu |
|
|
Sorafenib |
Influence on tumor growth |
Immunohistochemistry |
100.00 mg/kg |
U87-Luc |
Mus musculus |
NIH Nu/Nu |
|
|
STA-21 |
Influence on protein activity |
Luciferse activity |
30.00 µM |
Caov-3 |
Homo sapiens |
|
|
|
STA-21 |
Influence on protein-DNA binding |
Western Blot |
30.00 µM |
MDA-MB-435S |
Homo sapiens |
|
STAT3 |
|
STA-21 |
Influence on protein-DNA binding |
Western Blot |
30.00 µM |
MDA-MB-435S |
Homo sapiens |
|
STAT1 |
|