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Experiments

Compound Investigated event Experiment type Concentration Cell line Organism Animal model Stat protein Details
Sorafenib Influence on cell cycle Western Blot 3.00 µM U87 Homo sapiens
Sorafenib Influence on protein activity Western Blot 3.00 µM U87 Homo sapiens
Sorafenib Influence on protein activity Western Blot 7.00 µM U87 Homo sapiens
Sorafenib Influence on protein activity Western Blot 15.00 µM U87 Homo sapiens
Sorafenib Influence on protein activity Western Blot 3.00 µM U87 Homo sapiens
Sorafenib Influence on protein activity Western Blot 7.00 µM U87 Homo sapiens
Sorafenib Influence on protein activity Western Blot 15.00 µM U87 Homo sapiens
Sorafenib Influence on protein activity Western Blot 3.00 µM U87 Homo sapiens p-STAT3(Y705)
Sorafenib Influence on protein activity Western Blot 7.00 µM U87 Homo sapiens p-STAT3(Y705)
Sorafenib Influence on protein activity Western Blot 15.00 µM U87 Homo sapiens p-STAT3(Y705)
Sorafenib Influence on protein activity Western Blot 3.00 µM U87 Homo sapiens STAT3
Sorafenib Influence on protein activity Western Blot 7.00 µM U87 Homo sapiens STAT3
Sorafenib Influence on protein activity Western Blot 15.00 µM U87 Homo sapiens STAT3
Sorafenib Influence on protein activity Western Blot 3.00 µM U87 Homo sapiens
Sorafenib Influence on protein activity Western Blot 7.00 µM U87 Homo sapiens
Sorafenib Influence on protein activity Western Blot 15.00 µM U87 Homo sapiens
Sorafenib Influence on protein activity Western Blot 3.00 µM U87 Homo sapiens
Sorafenib Influence on protein activity Western Blot 7.00 µM U87 Homo sapiens
Sorafenib Influence on protein activity Western Blot 15.00 µM U87 Homo sapiens
Sorafenib Influence on protein activity Western Blot 3.00 µM U87 Homo sapiens
Sorafenib Influence on protein activity Western Blot 7.00 µM U87 Homo sapiens
Sorafenib Influence on protein activity Western Blot 15.00 µM U87 Homo sapiens
Sorafenib Influence on protein activity Western Blot 3.00 µM U87 Homo sapiens
Sorafenib Influence on protein activity Western Blot 7.00 µM U87 Homo sapiens
Sorafenib Influence on protein activity Western Blot 15.00 µM U87 Homo sapiens
Sorafenib Influence on protein activity Western Blot 3.00 µM U87 Homo sapiens
Sorafenib Influence on protein activity Western Blot 7.00 µM U87 Homo sapiens
Sorafenib Influence on protein activity Western Blot 15.00 µM U87 Homo sapiens
Sorafenib Influence on protein activity Western Blot 3.00 µM U87 Homo sapiens
Sorafenib Influence on protein activity Western Blot 7.00 µM U87 Homo sapiens
Sorafenib Influence on protein activity Western Blot 15.00 µM U87 Homo sapiens
Sorafenib Influence on cell viability Trypan Blue staining N/A µM U87 Homo sapiens
Sorafenib Influence on cell viability Trypan Blue staining N/A µM LN229 Homo sapiens
Sorafenib Influence on cell viability in transfected cells Western Blot 3.00 µM U87 Homo sapiens
Sorafenib Influence on cell viability in transfected cells Western Blot 7.00 µM U87 Homo sapiens
Sorafenib Influence on cell viability in transfected cells Western Blot 15.00 µM U87 Homo sapiens
Sorafenib Influence on cell viability in transfected cells Western Blot 3.00 µM U87 Homo sapiens
Sorafenib Influence on cell viability in transfected cells Western Blot 7.00 µM U87 Homo sapiens
Sorafenib Influence on cell viability in transfected cells Western Blot 15.00 µM U87 Homo sapiens
Sorafenib Influence on cell viability in transfected cells Western Blot 3.00 µM U87 Homo sapiens
Sorafenib Influence on cell viability in transfected cells Western Blot 7.00 µM U87 Homo sapiens
Sorafenib Influence on cell viability in transfected cells Western Blot 15.00 µM U87 Homo sapiens
Sorafenib Influence on tumor growth Bioluminescence 100.00 mg/kg U87-Luc Mus musculus NIH Nu/Nu
Sorafenib Influence on tumor growth Percent survival 100.00 mg/kg U87-Luc Mus musculus NIH Nu/Nu
Sorafenib Influence on tumor growth Immunohistochemistry 100.00 mg/kg U87-Luc Mus musculus NIH Nu/Nu
Sorafenib Influence on tumor growth Immunohistochemistry 100.00 mg/kg U87-Luc Mus musculus NIH Nu/Nu
Sorafenib Influence on tumor growth Immunohistochemistry 100.00 mg/kg U87-Luc Mus musculus NIH Nu/Nu
STA-21 Influence on protein activity Luciferse activity 30.00 µM Caov-3 Homo sapiens
STA-21 Influence on protein-DNA binding Western Blot 30.00 µM MDA-MB-435S Homo sapiens STAT3
STA-21 Influence on protein-DNA binding Western Blot 30.00 µM MDA-MB-435S Homo sapiens STAT1