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Experiments

Compound Investigated event Experiment type Concentration Cell line Organism Animal model Stat protein Details
KDI1 Influence on protein activity in presence of EGF Western Blot 1.00 µM Herc Homo sapiens STAT3
KDI1 Influence on protein activity in presence of EGF Immunofluorescence 1.00 µM Herc Homo sapiens p-STAT3 (Y705)
KDI1 Influence on protein activity in presence of EGF Immunofluorescence 1.00 µM Herc Homo sapiens STAT3
Niflumic Acid Influence on trachea and intrapulmonary bronchi in presence of IL-13 Alcian-blue staining 30.00 mg/kg Mus musculus A/J
Niflumic Acid Influence on gene expression in trachea and intrapulmonary bronchi in presence of IL-13 RT-PCR 30.00 mg/kg Mus musculus A/J
Niflumic Acid Influence on gene expression in trachea and intrapulmonary bronchi in presence of IL-13 RT-PCR 30.00 mg/kg Mus musculus A/J
Niflumic Acid Influence on airway responsiveness in presence of IL-13 BALF content analysis 30.00 mg/kg macrophages Mus musculus A/J
Niflumic Acid Influence on airway responsiveness in presence of IL-13 BALF content analysis 30.00 mg/kg neutrophils Mus musculus A/J
Niflumic Acid Influence on airway responsiveness in presence of IL-13 BALF content analysis 30.00 mg/kg lymphocytes Mus musculus A/J
Niflumic Acid Influence on airway responsiveness in presence of IL-13 BALF content analysis 30.00 mg/kg eosinophils Mus musculus A/J
Niflumic Acid Influence on protein activity in presence of IL-13 Western Blot 100.00 µM BEAS-2B Homo sapiens p-STAT6
Niflumic Acid Influence on protein activity in presence of IL-13 Western Blot 100.00 µM BEAS-2B Homo sapiens STAT6
Niflumic Acid Influence on protein activity in presence of IL-13 Western Blot 100.00 µM BEAS-2B Homo sapiens
Niflumic Acid Influence on protein activity in presence of IL-13 Western Blot 100.00 µM BEAS-2B Homo sapiens
Niflumic Acid Influence on gene expression in lung tissue in presence of IL-13 RT-PCR 30.00 mg/kg lung Mus musculus A/J
Niflumic Acid Influence on gene expression in lung tissue in presence of IL-13 RT-PCR 30.00 mg/kg lung Mus musculus A/J
Niflumic Acid Influence on gene expression in lung tissue in presence of IL-13 RT-PCR 30.00 mg/kg lung Mus musculus A/J
Niflumic Acid Influence on gene expression in lung tissue in presence of IL-13 RT-PCR 30.00 mg/kg lung Mus musculus A/J
Niflumic Acid Influence on gene expression in lung tissue in presence of IL-13 RT-PCR 30.00 mg/kg lung Mus musculus A/J
Niflumic Acid Influence on gene expression in lung tissue in presence of IL-13 RT-PCR 30.00 mg/kg lung Mus musculus A/J
Niflumic Acid Influence on gene expression in lung tissue in presence of IL-13 RT-PCR 30.00 mg/kg lung Mus musculus A/J
PM-73G Influence on protein astivity in tumor tissue Immunohistochemistry 200.00 µM MDA-MB-468 Homo sapiens p-STAT3
PM-73G Influence on protein astivity in tumor tissue Immunohistochemistry 40.00 µM MDA-MB-468 Homo sapiens p-STAT3
PM-73G Influence on protein astivity in tumor tissue Immunohistochemistry 8.00 µM MDA-MB-468 Homo sapiens p-STAT3
PM-73G Influence on protein astivity in tumor tissue Immunohistochemistry 1.60 µM MDA-MB-468 Homo sapiens p-STAT3
PM-73G Influence on protein astivity in tumor tissue Immunohistochemistry 0.30 µM MDA-MB-468 Homo sapiens p-STAT3
PM-73G Influence on protein astivity in tumor tissue Tumor volume 5.00 mM MDA-MB-468(xenograft) Mus musculus nude mice
PM-73G Influence on microvessel density Immunohistochemistry 5.00 mM MDA-MB-468(xenograft) Mus musculus nude mice p-STAT3
PM-73G Influence on microvessel density Immunohistochemistry 5.00 mM MDA-MB-468(xenograft) Mus musculus nude mice STAT3
PM-73G Influence on microvessel density Immunohistochemistry 5.00 mM MDA-MB-468(xenograft) Mus musculus nude mice
PM-73G Influence on microvessel density Immunohistochemistry 5.00 mM MDA-MB-468(xenograft) Mus musculus nude mice
PM-73G Influence on protein activity Western Blot 0.01 µM MDA-MB-468 Homo sapiens p-STAT3
PM-73G Influence on protein activity Western Blot 0.05 µM MDA-MB-468 Homo sapiens p-STAT3
PM-73G Influence on protein activity Western Blot 0.10 µM MDA-MB-468 Homo sapiens p-STAT3
PM-73G Influence on protein activity Western Blot 0.50 µM MDA-MB-468 Homo sapiens p-STAT3
PM-73G Influence on protein activity Western Blot 1.00 µM MDA-MB-468 Homo sapiens p-STAT3
PM-73G Influence on protein activity Western Blot 5.00 µM MDA-MB-468 Homo sapiens p-STAT3
PM-73G Influence on protein activity Western Blot 0.01 µM MDA-MB-468 Homo sapiens STAT3
PM-73G Influence on protein activity Western Blot 0.05 µM MDA-MB-468 Homo sapiens
PM-73G Influence on protein activity Western Blot 0.10 µM MDA-MB-468 Homo sapiens
PM-73G Influence on protein activity Western Blot 0.50 µM MDA-MB-468 Homo sapiens
PM-73G Influence on protein activity Western Blot 1.00 µM MDA-MB-468 Homo sapiens
PM-73G Influence on protein activity Western Blot 5.00 µM MDA-MB-468 Homo sapiens
PM-73G Influence on protein activity in presence of IFNγ Western Blot 0.01 µM MDA-MB-468 Homo sapiens p-STAT1
PM-73G Influence on protein activity in presence of IFNγ Western Blot 0.05 µM MDA-MB-468 Homo sapiens p-STAT1
PM-73G Influence on protein activity in presence of IFNγ Western Blot 0.10 µM MDA-MB-468 Homo sapiens p-STAT1
PM-73G Influence on protein activity in presence of IFNγ Western Blot 0.50 µM MDA-MB-468 Homo sapiens p-STAT1
PM-73G Influence on protein activity in presence of IFNγ Western Blot 1.00 µM MDA-MB-468 Homo sapiens p-STAT1
PM-73G Influence on protein activity in presence of IFNγ Western Blot 5.00 µM MDA-MB-468 Homo sapiens p-STAT1
PM-73G Influence on protein activity in presence of IFNγ Western Blot 0.01 µM MDA-MB-468 Homo sapiens STAT1