| Gefitinib |
Inlfuence on cell cycle |
Flow cytometry- annexin V binding and propidium iodide staining |
10.00 µM |
NCI‑H1975 |
Homo sapiens |
|
|
|
| Gefitinib |
Inlfuence on cell cycle in presence of DHA |
Western Blot |
10.00 µM |
NCI‑H1975 |
Homo sapiens |
|
|
|
| Gefitinib |
Inlfuence on cell cycle |
Western Blot |
10.00 µM |
NCI‑H1975 |
Homo sapiens |
|
|
|
| Gefitinib |
Inlfuence on cell cycle in presence of DHA |
Western Blot |
10.00 µM |
NCI‑H1975 |
Homo sapiens |
|
|
|
| Gefitinib |
Inlfuence on cell cycle |
Western Blot |
10.00 µM |
NCI‑H1975 |
Homo sapiens |
|
|
|
| Gefitinib |
Inlfuence on cell cycle in presence of DHA |
Western Blot |
10.00 µM |
NCI‑H1975 |
Homo sapiens |
|
|
|
| Gefitinib |
Inlfuence on cell cycle |
Western Blot |
10.00 µM |
NCI‑H1975 |
Homo sapiens |
|
|
|
| Gefitinib |
Influence on cell motility |
Invasion assay |
10.00 µM |
NCI‑H1975 |
Homo sapiens |
|
|
|
| Gefitinib |
Influence on cell motility in presence of DHA |
Invasion assay |
10.00 µM |
NCI‑H1975 |
Homo sapiens |
|
|
|
| Gefitinib |
Influence on protein activity |
Western Blot |
10.00 µM |
NCI‑H1975 |
Homo sapiens |
|
|
|
| Gefitinib |
Influence on protein activity in presence of DHA |
Western Blot |
10.00 µM |
NCI‑H1975 |
Homo sapiens |
|
|
|
| Gefitinib |
Influence on protein activity |
Western Blot |
10.00 µM |
NCI‑H1975 |
Homo sapiens |
|
|
|
| Gefitinib |
Influence on protein activity in presence of DHA |
Western Blot |
10.00 µM |
NCI‑H1975 |
Homo sapiens |
|
|
|
| Gefitinib |
Influence on protein activity |
Western Blot |
10.00 µM |
NCI‑H1975 |
Homo sapiens |
|
|
|
| Gefitinib |
Influence on protein activity in presence of DHA |
Western Blot |
10.00 µM |
NCI‑H1975 |
Homo sapiens |
|
|
|
| Gefitinib |
Influence on protein activity |
Western Blot |
10.00 µM |
NCI‑H1975 |
Homo sapiens |
|
|
|
| Gefitinib |
Influence on protein activity in presence of DHA |
Western Blot |
10.00 µM |
NCI‑H1975 |
Homo sapiens |
|
|
|
| Gefitinib |
Influence on protein activity |
Western Blot |
10.00 µM |
NCI‑H1975 |
Homo sapiens |
|
STAT3 |
|
| Gefitinib |
Influence on protein activity in presence of DHA |
Western Blot |
10.00 µM |
NCI‑H1975 |
Homo sapiens |
|
STAT3 |
|
| Gefitinib |
Influence on protein activity |
Western Blot |
10.00 µM |
NCI‑H1975 |
Homo sapiens |
|
p-STAT3 |
|
| Gefitinib |
Influence on protein activity in presence of DHA |
Western Blot |
10.00 µM |
NCI‑H1975 |
Homo sapiens |
|
p-STAT3 |
|
| Gefitinib |
Influence on protein activity |
Western Blot |
10.00 µM |
NCI‑H1975 |
Homo sapiens |
|
|
|
| Gefitinib |
Influence on protein activity in presence of DHA |
Western Blot |
10.00 µM |
NCI‑H1975 |
Homo sapiens |
|
|
|
| Gefitinib |
Influence on protein activity |
Western Blot |
10.00 µM |
NCI‑H1975 |
Homo sapiens |
|
|
|
| Gefitinib |
Influence on protein activity in presence of DHA |
Western Blot |
10.00 µM |
NCI‑H1975 |
Homo sapiens |
|
|
|
| Imatinib |
Influence on liver enzyme secretion in presence of LPS |
ELISA |
15.00 mg/kg |
blood |
Rattus norvegicus |
Wistar |
|
|
| Imatinib |
Influence on liver enzyme secretion in presence of LPS |
ELISA |
15.00 mg/kg |
blood |
Rattus norvegicus |
Wistar |
|
|
| Imatinib |
Influence on liver enzyme secretion in presence of LPS |
ELISA |
15.00 mg/kg |
blood |
Rattus norvegicus |
Wistar |
|
|
| Imatinib |
Influence on liver enzyme secretion in presence of LPS |
ELISA |
15.00 mg/kg |
blood |
Rattus norvegicus |
Wistar |
|
|
| Imatinib |
Influence on protein activity in liver tissue in presence of LPS |
Western Blot |
15.00 mg/kg |
liver |
Rattus norvegicus |
Wistar |
|
|
| Imatinib |
Influence on protein activity in liver tissue in presence of LPS |
Western Blot |
15.00 mg/kg |
liver |
Rattus norvegicus |
Wistar |
STAT3 |
|
| Imatinib |
Influence on protein activity in liver tissue in presence of LPS |
Western Blot |
15.00 mg/kg |
liver |
Rattus norvegicus |
Wistar |
|
|
| Imatinib |
Influence on protein activity in liver tissue in presence of LPS |
Western Blot |
15.00 mg/kg |
liver |
Rattus norvegicus |
Wistar |
|
|
| Imatinib |
Influence on protein activity in kidney tissue in presence of LPS |
Western Blot |
15.00 mg/kg |
kidney |
Rattus norvegicus |
Wistar |
|
|
| Imatinib |
Influence on protein activity in kidney tissue in presence of LPS |
Western Blot |
15.00 mg/kg |
kidney |
Rattus norvegicus |
Wistar |
STAT3 |
|
| Imatinib |
Influence on protein activity in kidney tissue in presence of LPS |
Western Blot |
15.00 mg/kg |
kidney |
Rattus norvegicus |
Wistar |
|
|
| Imatinib |
Influence on protein activity in kidney tissue in presence of LPS |
Western Blot |
15.00 mg/kg |
kidney |
Rattus norvegicus |
Wistar |
|
|
| Imatinib |
Influence on protein activity in lung tissue in presence of LPS |
Western Blot |
15.00 mg/kg |
lung |
Rattus norvegicus |
Wistar |
|
|
| Imatinib |
Influence on protein activity in lung tissue in presence of LPS |
Western Blot |
15.00 mg/kg |
lung |
Rattus norvegicus |
Wistar |
STAT3 |
|
| Imatinib |
Influence on protein activity in lung tissue in presence of LPS |
Western Blot |
15.00 mg/kg |
lung |
Rattus norvegicus |
Wistar |
|
|
| Imatinib |
Influence on protein activity in lung tissue in presence of LPS |
Western Blot |
15.00 mg/kg |
lung |
Rattus norvegicus |
Wistar |
|
|
| Imatinib |
Influence on mRNA expression in liver tissue in presence of LPS |
RT-qPCR |
15.00 mg/kg |
liver |
Rattus norvegicus |
Wistar |
|
|
| Imatinib |
Influence on mRNA expression in kidney tissue in presence of LPS |
RT-qPCR |
15.00 mg/kg |
kidney |
Rattus norvegicus |
Wistar |
|
|
| Imatinib |
Influence on mRNA expression in lung tissue in presence of LPS |
RT-qPCR |
15.00 mg/kg |
lung |
Rattus norvegicus |
Wistar |
|
|
| Imatinib |
Influence on mRNA expression in liver tissue in presence of LPS |
RT-qPCR |
15.00 mg/kg |
liver |
Rattus norvegicus |
Wistar |
|
|
| Imatinib |
Influence on mRNA expression in kidney tissue in presence of LPS |
RT-qPCR |
15.00 mg/kg |
kidney |
Rattus norvegicus |
Wistar |
|
|
| Imatinib |
Influence on mRNA expression in lung tissue in presence of LPS |
RT-qPCR |
15.00 mg/kg |
lung |
Rattus norvegicus |
Wistar |
|
|
| Methotrexate |
Influence on transcriptional activity |
Luciferase activity |
50.00 µM |
Kc167 |
Drosophila melanogaster |
|
|
|
| Methotrexate |
Influence on transcriptional activity |
Luciferase activity |
10.00 µM |
Kc167 |
Drosophila melanogaster |
|
|
|
| Methotrexate |
Influence on transcriptional activity |
Luciferase activity |
1.00 µM |
Kc167 |
Drosophila melanogaster |
|
|
|
