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Experiments

Compound Investigated event Experiment type Concentration Cell line Organism Animal model Stat protein Details
3,3 diindolylmethane Influence on protein activity in epithelial cells Western Blot 25.00 µM NOSE Homo sapiens p-STAT3 (Y705)
3,3 diindolylmethane Influence on protein activity in epithelial cells Western Blot 50.00 µM NOSE Homo sapiens p-STAT3 (Y705)
3,3 diindolylmethane Influence on protein activity in epithelial cells Western Blot 75.00 µM NOSE Homo sapiens p-STAT3 (Y705)
3,3 diindolylmethane Influence on protein activity in epithelial cells Western Blot 25.00 µM NOSE Homo sapiens STAT3
3,3 diindolylmethane Influence on protein activity in epithelial cells Western Blot 50.00 µM NOSE Homo sapiens STAT3
3,3 diindolylmethane Influence on protein activity in epithelial cells Western Blot 75.00 µM NOSE Homo sapiens STAT3
3,3 diindolylmethane Influence on protein activity in epithelial cells Western Blot 25.00 µM NOSE Homo sapiens
3,3 diindolylmethane Influence on protein activity in epithelial cells Western Blot 50.00 µM NOSE Homo sapiens
3,3 diindolylmethane Influence on protein activity in epithelial cells Western Blot 75.00 µM NOSE Homo sapiens
5,15-DPP Influence on protin activity in presence of IL-10 Immunohistochemistry 5.00 mM 264.7 RAW Mus musculus STAT3
5,15-DPP Influence on protin activity in presence of IL-10 Western Blot 5.00 mM 264.7 RAW Mus musculus p-STAT3 (Y705)
5,15-DPP Influence on protin activity in presence of IL-10 Western Blot 5.00 mM 264.7 RAW Mus musculus STAT3α
5,15-DPP Influence on protin activity in presence of IL-10 Western Blot 5.00 mM 264.7 RAW Mus musculus
5,15-DPP Influence on cell proliferation in presence of IL-10 [3H] thymidine 5.00 mM HMVEC Mus musculus
AS1517499 Influence on protin activity Western Blot 10.00 nM 264.7 RAW Mus musculus p-STAT6
AS1517499 Influence on protin activity Western Blot 100.00 nM 264.7 RAW Mus musculus p-STAT6
AS1517499 Influence on protin activity Western Blot 250.00 nM 264.7 RAW Mus musculus p-STAT6
AS1517499 Influence on protin activity Western Blot 10.00 nM 264.7 RAW Mus musculus STAT6
AS1517499 Influence on protin activity Western Blot 100.00 nM 264.7 RAW Mus musculus STAT6
AS1517499 Influence on protin activity Western Blot 250.00 nM 264.7 RAW Mus musculus STAT6
AS1517499 Influence on protin activity Western Blot 10.00 nM 264.7 RAW Mus musculus
AS1517499 Influence on protin activity Western Blot 100.00 nM 264.7 RAW Mus musculus
AS1517499 Influence on protin activity Western Blot 250.00 nM 264.7 RAW Mus musculus
AS1517499 Influence on macrophage differentiation RT-qPCR 10.00 nM 264.7 RAW Mus musculus
AS1517499 Influence on macrophage differentiation RT-qPCR 100.00 nM 264.7 RAW Mus musculus
AS1517499 Influence on macrophage differentiation RT-qPCR 250.00 nM 264.7 RAW Mus musculus
AS1517499 Influence on macrophage differentiation RT-qPCR 10.00 nM 264.7 RAW Mus musculus
AS1517499 Influence on macrophage differentiation RT-qPCR 100.00 nM 264.7 RAW Mus musculus
AS1517499 Influence on macrophage differentiation RT-qPCR 250.00 nM 264.7 RAW Mus musculus
AS1517499 Influence on macrophage differentiation RT-qPCR 10.00 nM 264.7 RAW Mus musculus
AS1517499 Influence on macrophage differentiation RT-qPCR 100.00 nM 264.7 RAW Mus musculus
AS1517499 Influence on macrophage differentiation RT-qPCR 250.00 nM 264.7 RAW Mus musculus
AS1517499 Influence on macrophage differentiation RT-qPCR 10.00 nM 264.7 RAW Mus musculus
AS1517499 Influence on macrophage differentiation RT-qPCR 100.00 nM 264.7 RAW Mus musculus
AS1517499 Influence on macrophage differentiation RT-qPCR 250.00 nM 264.7 RAW Mus musculus
AS1517499 Influence on cell viability Resazurin sodium salt 100.00 nM 4T1-luc Mus musculus
AS1517499 Influence on cell viability Resazurin sodium salt 250.00 nM 4T1-luc Mus musculus
AS1517499 Influence on cell proliferation in tumor tissue Tumor volume 20.00 mg/kg 4T1-luc (xenograft) Mus musculus BALB/c
AS1517499 Influence on cell proliferation in tumor tissue IVIS in vivo imaging 20.00 mg/kg 4T1-luc (xenograft) Mus musculus BALB/c
AS1517499 Influence on tumor metastasis IVIS in vivo imaging 20.00 mg/kg liver Mus musculus BALB/c
AS1517499 Influence on tumor progression RT-qPCR 20.00 mg/kg macrophages Mus musculus BALB/c
AS1517499 Influence on tumor progression RT-qPCR 20.00 mg/kg macrophages Mus musculus BALB/c
AS1517499 Influence on tumor progression RT-qPCR 20.00 mg/kg macrophages Mus musculus BALB/c
AS1517499 Influence on tumor progression RT-qPCR 20.00 mg/kg liver Mus musculus BALB/c
AS1517499 Influence on tumor progression RT-qPCR 20.00 mg/kg liver Mus musculus BALB/c
AS1517499 Influence on tumor progression RT-qPCR 20.00 mg/kg liver Mus musculus BALB/c
AS1517499 Influence on cytokine expression in transplanted organ RT-qPCR 10.00 mg/kg kidney Rattus norvegicus Lewis and Brown Norway
AS1517499 Influence on cytokine expression in transplanted organ RT-qPCR 10.00 mg/kg kidney Rattus norvegicus Lewis and Brown Norway
AS1517499 Influence on cytokine expression in transplanted organ RT-qPCR 10.00 mg/kg kidney Rattus norvegicus Lewis and Brown Norway
AS1517499 Influence on cytokine expression in serum ELISA 10.00 mg/kg kidney Rattus norvegicus Lewis and Brown Norway