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Experiments

Compound Investigated event Experiment type Concentration Cell line Organism Animal model Stat protein Details
XZH-5 Influence on cell apoptosis Caspase 3/7 assay 50.00 µM SW1990 Homo sapiens
XZH-5 Influence on protein activity in presence of IL-6 Western Blot 25.00 µM MCF-7 Homo sapiens p-STAT3 (Y705)
XZH-5 Influence on protein activity in presence of IL-6 Western Blot 50.00 µM MCF-7 Homo sapiens p-STAT3 (Y705)
XZH-5 Influence on protein activity in presence of IL-6 Western Blot 25.00 µM AsPC-1 Homo sapiens p-STAT3 (Y705)
XZH-5 Influence on protein activity in presence of IL-6 Western Blot 50.00 µM AsPC-1 Homo sapiens p-STAT3 (Y705)
XZH-5 Influence on protein activity in presence of IL-6 Western Blot 25.00 µM MCF-7 Homo sapiens STAT3
XZH-5 Influence on protein activity in presence of IL-6 Western Blot 50.00 µM MCF-7 Homo sapiens STAT3
XZH-5 Influence on protein activity in presence of IL-6 Western Blot 25.00 µM AsPC-1 Homo sapiens STAT3
XZH-5 Influence on protein activity in presence of IL-6 Western Blot 50.00 µM AsPC-1 Homo sapiens STAT3
XZH-5 Influence on protein activity in presence of IL-6 Western Blot 25.00 µM MCF-7 Homo sapiens
XZH-5 Influence on protein activity in presence of IL-6 Western Blot 50.00 µM MCF-7 Homo sapiens
XZH-5 Influence on protein activity in presence of IL-6 Western Blot 25.00 µM AsPC-1 Homo sapiens
XZH-5 Influence on protein activity in presence of IL-6 Western Blot 50.00 µM AsPC-1 Homo sapiens
XZH-5 Influence on protein activity in presence of IFNγ Western Blot 25.00 µM MCF-7 Homo sapiens p-STAT1 (Y701)
XZH-5 Influence on protein activity in presence of IFNγ Western Blot 50.00 µM MCF-7 Homo sapiens p-STAT1 (Y701)
XZH-5 Influence on protein activity in presence of IFNγ Western Blot 25.00 µM AsPC-1 Homo sapiens p-STAT1 (Y701)
XZH-5 Influence on protein activity in presence of IFNγ Western Blot 50.00 µM AsPC-1 Homo sapiens p-STAT1 (Y701)
XZH-5 Influence on protein activity in presence of IFNγ Western Blot 25.00 µM MCF-7 Homo sapiens STAT1
XZH-5 Influence on protein activity in presence of IFNγ Western Blot 50.00 µM MCF-7 Homo sapiens STAT1
XZH-5 Influence on protein activity in presence of IFNγ Western Blot 25.00 µM AsPC-1 Homo sapiens STAT1
XZH-5 Influence on protein activity in presence of IFNγ Western Blot 50.00 µM AsPC-1 Homo sapiens STAT1
XZH-5 Influence on protein activity in presence of IFNγ Western Blot 25.00 µM MCF-7 Homo sapiens
XZH-5 Influence on protein activity in presence of IFNγ Western Blot 50.00 µM MCF-7 Homo sapiens
XZH-5 Influence on protein activity in presence of IFNγ Western Blot 25.00 µM AsPC-1 Homo sapiens
XZH-5 Influence on protein activity in presence of IFNγ Western Blot 50.00 µM AsPC-1 Homo sapiens
XZH-5 Influence on protein translocation in presence of IL-6 Immunofluorescence 50.00 µM MCF-7 Homo sapiens p-STAT3
XZH-5 Influence on protein translocation in presence of IL-6 Immunofluorescence 50.00 µM MCF-7 Homo sapiens STAT3
XZH-5 Influence on cell motility Colony formation assay 30.00 µM MDA-MB-231 Homo sapiens
XZH-5 Influence on cell motility Colony formation assay 40.00 µM MDA-MB-231 Homo sapiens
XZH-5 Influence on cell motility Colony formation assay 25.00 µM Panc-1 Homo sapiens
XZH-5 Influence on cell motility Colony formation assay 50.00 µM Panc-1 Homo sapiens
XZH-5 Influence on cell motility Wound healing assay 30.00 µM MDA-MB-231 Homo sapiens
XZH-5 Influence on cell motility Wound healing assay 40.00 µM MDA-MB-231 Homo sapiens
XZH-5 Influence on cell motility Wound healing assay 25.00 µM Panc-1 Homo sapiens
XZH-5 Influence on cell motility Wound healing assay 50.00 µM Panc-1 Homo sapiens
XZH-5 Influence on cell viability CyQUANT 15.00 µM MDA-MB-231 Homo sapiens
XZH-5 Influence on cell viability CyQUANT 20.00 µM MDA-MB-231 Homo sapiens
XZH-5 Influence on cell viability CyQUANT 15.00 µM Panc-1 Homo sapiens
XZH-5 Influence on cell viability CyQUANT 20.00 µM Panc-1 Homo sapiens
XZH-5 Influence on cell viability in presence of chemiterapeutic CyQUANT 15.00 µM MDA-MB-231 Homo sapiens
XZH-5 Influence on cell viability in presence of chemiterapeutic CyQUANT 20.00 µM MDA-MB-231 Homo sapiens
XZH-5 Influence on cell viability in presence of chemiterapeutic CyQUANT 15.00 µM Panc-1 Homo sapiens
XZH-5 Influence on cell viability in presence of chemiterapeutic CyQUANT 20.00 µM Panc-1 Homo sapiens
TG101209 Influence on protein activity Western Blot 1.00 µM HCC2429 Homo sapiens p-STAT3
TG101209 Influence on protein activity Western Blot 3.00 µM HCC2429 Homo sapiens p-STAT3
TG101209 Influence on protein activity Western Blot 1.00 µM H460 Homo sapiens p-STAT3
TG101209 Influence on protein activity Western Blot 3.00 µM H460 Homo sapiens p-STAT3
TG101209 Influence on protein activity Western Blot 1.00 µM HCC2429 Homo sapiens STAT3
TG101209 Influence on protein activity Western Blot 3.00 µM HCC2429 Homo sapiens STAT3
TG101209 Influence on protein activity Western Blot 1.00 µM H460 Homo sapiens STAT3