XZH-5

Name Value
Weight 537.461 g/mol
Zinc ID ZINC299867275
Smiles COC(=O)[C@H](Cc1cn(C)cn1)NC(=O)[C@@H](NC(=O)Nc1cc(C(F)(F)F)cc(C(F)(F)F)c1)C(C)C
Molecular formula C22H25F6N5O4
Mode of inhibition N/A
CAS N/A

Clinical Trials

Study title Status Conditions Link

References

Publication DOI Pubmed PMCID
Novel small molecule, XZH-5, inhibits constitutive and interleukin-6-induced STAT3 phosphorylation in human rhabdomyosarcoma cells. Cancer science Aiguo Liu, Yan Liu, Zhenghu Xu, Wenying Yu, Hong Wang, Chenglong Li, Jiayuh Lin, 102, 7, None, 2011-05-05, 10.1111/j.1349-7006.2011.01932 10.1111/j.1349-7006.2011.01932 21435102 21435102
XZH-5 inhibits STAT3 phosphorylation and causes apoptosis in human hepatocellular carcinoma cells. Apoptosis : an international journal on programmed cell death Yan Liu, Aiguo Liu, Zhenghu Xu, Wenying Yu, Hong Wang, Chenglong Li, Jiayuh Lin, 16, 5, None, None, 10.1007/s10495-011-0578-0. 10.1007/s10495-011-0578-0. 21311975 21311975
XZH-5 inhibits STAT3 phosphorylation and enhances the cytotoxicity of chemotherapeutic drugs in human breast and pancreatic cancer cells. PloS one Aiguo Liu, Yan Liu, Zhigang Jin, Qun Hu, Li Lin, David Jou, Jing Yang, Zhenghu Xu, Hong Wang, Chenglong Li, Jiayuh Lin, 7, 10, None, 2012-10-03, 10.1371/journal.pone.0046624 10.1371/journal.pone.0046624 23056374 PMC3463519

Vendors

Company Lnk to product
Glixx Laboratories http://glixxlabs.com/chemical-products/bioactive-screen-leads_p5/GLXC-02044
Chemexpress https://www.chemexpress.cn/1360562-98-6.htm

Filter data

Compound XZH-5
Experiment types Caspase 3/7 assay , Colony formation assay , CyQUANT, ELISA, Immunofluorescence, Immunostaining , RT-PCR, Western Blot, Wound healing assay
Concentrations 10.00, 15.00, 20.00, 25.00, 30.00, 40.00, 50.00
Cell lines AsPC-1, HH, Hep3B, HepG2, Huh-7, MCF-7, MDA-MB-231, Panc-1, RD2, RH28, Rh30, SMS-CTR, SNU-387, SNU-398, SUM 159, SW1990
Organisms Homo sapiens
Animal models
STAT proteins STAT1, STAT3, p-STAT1 (Y701), p-STAT1 (Y7010, p-STAT3, p-STAT3 (Y705)
Other Bax, Bcl-2, Bcl-xL, Cleaved Caspase-3, Cleaved PARP, Cleaved caspase-3, Cyclin D1, Cyclin D1 , GAPDH, HIF-1α, JAK1, JAK2, Survivin, VEGF, p-JAK1 (Y1007/1008), p-p65, p65

Experiments

Compound Experiment type Investigated event Concentration Cell line Organism Animal model Stat protein Details
XZH-5 Western Blot Influence on protein activity 25.00 µM RD2 Homo sapiens p-STAT3 (Y705)
XZH-5 Western Blot Influence on protein activity 50.00 µM RD2 Homo sapiens p-STAT3 (Y705)
XZH-5 Western Blot Influence on protein activity 25.00 µM RH28 Homo sapiens p-STAT3 (Y705)
XZH-5 Western Blot Influence on protein activity 50.00 µM RH28 Homo sapiens p-STAT3 (Y705)
XZH-5 Western Blot Influence on protein activity 25.00 µM Rh30 Homo sapiens p-STAT3 (Y705)
XZH-5 Western Blot Influence on protein activity 50.00 µM Rh30 Homo sapiens p-STAT3 (Y705)
XZH-5 Western Blot Influence on protein activity 25.00 µM RD2 Homo sapiens STAT3
XZH-5 Western Blot Influence on protein activity 50.00 µM RD2 Homo sapiens STAT3
XZH-5 Western Blot Influence on protein activity 25.00 µM RH28 Homo sapiens STAT3
XZH-5 Western Blot Influence on protein activity 50.00 µM RH28 Homo sapiens STAT3
XZH-5 Western Blot Influence on protein activity 25.00 µM Rh30 Homo sapiens STAT3
XZH-5 Western Blot Influence on protein activity 50.00 µM Rh30 Homo sapiens STAT3
XZH-5 Western Blot Influence on protein activity 25.00 µM RD2 Homo sapiens
XZH-5 Western Blot Influence on protein activity 50.00 µM RD2 Homo sapiens
XZH-5 Western Blot Influence on protein activity 25.00 µM RH28 Homo sapiens
XZH-5 Western Blot Influence on protein activity 50.00 µM RH28 Homo sapiens
XZH-5 Western Blot Influence on protein activity 10.00 µM Rh30 Homo sapiens
XZH-5 Western Blot Influence on protein activity 25.00 µM Rh30 Homo sapiens
XZH-5 ELISA Influence on protein-DNA interaction 25.00 µM Rh30 Homo sapiens STAT3
XZH-5 RT-PCR Influence on expression of proteins downstream target genes 50.00 µM RD2 Homo sapiens
XZH-5 RT-PCR Influence on expression of proteins downstream target genes 50.00 µM RH28 Homo sapiens
XZH-5 RT-PCR Influence on expression of proteins downstream target genes 25.00 µM Rh30 Homo sapiens
XZH-5 RT-PCR Influence on expression of proteins downstream target genes 50.00 µM RD2 Homo sapiens
XZH-5 RT-PCR Influence on expression of proteins downstream target genes 50.00 µM RH28 Homo sapiens
XZH-5 RT-PCR Influence on expression of proteins downstream target genes 25.00 µM Rh30 Homo sapiens
XZH-5 RT-PCR Influence on expression of proteins downstream target genes 50.00 µM RD2 Homo sapiens
XZH-5 RT-PCR Influence on expression of proteins downstream target genes 50.00 µM RH28 Homo sapiens
XZH-5 RT-PCR Influence on expression of proteins downstream target genes 25.00 µM Rh30 Homo sapiens
XZH-5 RT-PCR Influence on expression of proteins downstream target genes 50.00 µM RD2 Homo sapiens
XZH-5 RT-PCR Influence on expression of proteins downstream target genes 50.00 µM RH28 Homo sapiens
XZH-5 RT-PCR Influence on expression of proteins downstream target genes 25.00 µM Rh30 Homo sapiens
XZH-5 RT-PCR Influence on expression of proteins downstream target genes 50.00 µM RD2 Homo sapiens
XZH-5 RT-PCR Influence on expression of proteins downstream target genes 50.00 µM RH28 Homo sapiens
XZH-5 RT-PCR Influence on expression of proteins downstream target genes 25.00 µM Rh30 Homo sapiens
XZH-5 Western Blot Influence on cell viability 50.00 µM RD2 Homo sapiens
XZH-5 Western Blot Influence on cell viability 50.00 µM RH28 Homo sapiens
XZH-5 Western Blot Influence on cell viability 25.00 µM Rh30 Homo sapiens
XZH-5 Western Blot Influence on cell viability 50.00 µM SMS-CTR Homo sapiens
XZH-5 Western Blot Influence on cell viability 50.00 µM RD2 Homo sapiens
XZH-5 Western Blot Influence on cell viability 50.00 µM RH28 Homo sapiens
XZH-5 Western Blot Influence on cell viability 25.00 µM Rh30 Homo sapiens
XZH-5 Western Blot Influence on cell viability 50.00 µM SMS-CTR Homo sapiens
XZH-5 Western Blot Influence on cell viability 50.00 µM RD2 Homo sapiens
XZH-5 Western Blot Influence on cell viability 50.00 µM RH28 Homo sapiens
XZH-5 Western Blot Influence on cell viability 25.00 µM Rh30 Homo sapiens
XZH-5 Western Blot Influence on cell viability 50.00 µM SMS-CTR Homo sapiens
XZH-5 Caspase 3/7 assay Influence on cell viability 50.00 µM RD2 Homo sapiens
XZH-5 Caspase 3/7 assay Influence on cell viability 50.00 µM RH28 Homo sapiens
XZH-5 Caspase 3/7 assay Influence on cell viability 25.00 µM Rh30 Homo sapiens
XZH-5 Caspase 3/7 assay Influence on cell viability 50.00 µM SMS-CTR Homo sapiens
XZH-5 CyQUANT Influence on cell viability 50.00 µM RD2 Homo sapiens
XZH-5 CyQUANT Influence on cell viability 50.00 µM RH28 Homo sapiens
XZH-5 CyQUANT Influence on cell viability 25.00 µM Rh30 Homo sapiens
XZH-5 CyQUANT Influence on cell viability 50.00 µM SMS-CTR Homo sapiens
XZH-5 Western Blot Influence on protein activity in presence of IL-6 25.00 µM SMS-CTR Homo sapiens p-STAT3 (Y705)
XZH-5 Western Blot Influence on protein activity in presence of IL-6 50.00 µM SMS-CTR Homo sapiens p-STAT3 (Y705)
XZH-5 Western Blot Influence on protein activity in presence of IL-6 25.00 µM SMS-CTR Homo sapiens STAT3
XZH-5 Western Blot Influence on protein activity in presence of IL-6 50.00 µM SMS-CTR Homo sapiens STAT3
XZH-5 Western Blot Influence on protein activity in presence of IL-6 25.00 µM SMS-CTR Homo sapiens
XZH-5 Western Blot Influence on protein activity in presence of IL-6 50.00 µM SMS-CTR Homo sapiens
XZH-5 Western Blot Influence on protein activity in presence of IL-6 25.00 µM SMS-CTR Homo sapiens p-STAT1 (Y7010
XZH-5 Western Blot Influence on protein activity in presence of IL-6 50.00 µM SMS-CTR Homo sapiens p-STAT1 (Y7010
XZH-5 Western Blot Influence on protein activity in presence of IL-6 25.00 µM SMS-CTR Homo sapiens STAT1
XZH-5 Western Blot Influence on protein activity in presence of IL-6 50.00 µM SMS-CTR Homo sapiens STAT1
XZH-5 Immunofluorescence Influence on protein translocation in presence of IL-6 50.00 µM SMS-CTR Homo sapiens STAT3
XZH-5 Colony formation assay Influence on cell motility 50.00 µM RD2 Homo sapiens
XZH-5 Colony formation assay Influence on cell motility 50.00 µM RH28 Homo sapiens
XZH-5 Colony formation assay Influence on cell motility 25.00 µM Rh30 Homo sapiens
XZH-5 Wound healing assay Influence on cell motility 10.00 µM RD2 Homo sapiens
XZH-5 Wound healing assay Influence on cell motility 25.00 µM RD2 Homo sapiens
XZH-5 Wound healing assay Influence on cell motility 50.00 µM RD2 Homo sapiens
XZH-5 Wound healing assay Influence on cell motility 10.00 µM RH28 Homo sapiens
XZH-5 Wound healing assay Influence on cell motility 25.00 µM RH28 Homo sapiens
XZH-5 Wound healing assay Influence on cell motility 50.00 µM RH28 Homo sapiens
XZH-5 Wound healing assay Influence on cell motility 10.00 µM Rh30 Homo sapiens
XZH-5 Wound healing assay Influence on cell motility 25.00 µM Rh30 Homo sapiens
XZH-5 Wound healing assay Influence on cell motility 50.00 µM Rh30 Homo sapiens
XZH-5 Western Blot Influence on protein activity 20.00 µM SNU-387 Homo sapiens p-STAT3 (Y705)
XZH-5 Western Blot Influence on protein activity 30.00 µM SNU-387 Homo sapiens p-STAT3 (Y705)
XZH-5 Western Blot Influence on protein activity 40.00 µM SNU-387 Homo sapiens p-STAT3 (Y705)
XZH-5 Western Blot Influence on protein activity 20.00 µM SNU-398 Homo sapiens p-STAT3 (Y705)
XZH-5 Western Blot Influence on protein activity 30.00 µM SNU-398 Homo sapiens p-STAT3 (Y705)
XZH-5 Western Blot Influence on protein activity 20.00 µM HepG2 Homo sapiens p-STAT3 (Y705)
XZH-5 Western Blot Influence on protein activity 30.00 µM HepG2 Homo sapiens p-STAT3 (Y705)
XZH-5 Western Blot Influence on protein activity 30.00 µM Huh-7 Homo sapiens p-STAT3 (Y705)
XZH-5 Western Blot Influence on protein activity 40.00 µM Huh-7 Homo sapiens p-STAT3 (Y705)
XZH-5 Western Blot Influence on protein activity 20.00 µM SNU-387 Homo sapiens STAT3
XZH-5 Western Blot Influence on protein activity 30.00 µM SNU-387 Homo sapiens STAT3
XZH-5 Western Blot Influence on protein activity 40.00 µM SNU-387 Homo sapiens STAT3
XZH-5 Western Blot Influence on protein activity 20.00 µM SNU-398 Homo sapiens STAT3
XZH-5 Western Blot Influence on protein activity 30.00 µM SNU-398 Homo sapiens STAT3
XZH-5 Western Blot Influence on protein activity 20.00 µM HepG2 Homo sapiens STAT3
XZH-5 Western Blot Influence on protein activity 30.00 µM HepG2 Homo sapiens STAT3
XZH-5 Western Blot Influence on protein activity 30.00 µM Huh-7 Homo sapiens STAT3
XZH-5 Western Blot Influence on protein activity 40.00 µM Huh-7 Homo sapiens STAT3
XZH-5 Western Blot Influence on protein activity 20.00 µM SNU-387 Homo sapiens
XZH-5 Western Blot Influence on protein activity 30.00 µM SNU-387 Homo sapiens
XZH-5 Western Blot Influence on protein activity 40.00 µM SNU-387 Homo sapiens
XZH-5 Western Blot Influence on protein activity 20.00 µM SNU-398 Homo sapiens
XZH-5 Western Blot Influence on protein activity 30.00 µM SNU-398 Homo sapiens
XZH-5 Western Blot Influence on protein activity 20.00 µM HepG2 Homo sapiens
XZH-5 Western Blot Influence on protein activity 30.00 µM HepG2 Homo sapiens
XZH-5 Western Blot Influence on protein activity 30.00 µM Huh-7 Homo sapiens
XZH-5 Western Blot Influence on protein activity 40.00 µM Huh-7 Homo sapiens
XZH-5 RT-PCR Influence on expression of proteins downstream target genes 30.00 µM SNU-387 Homo sapiens
XZH-5 RT-PCR Influence on expression of proteins downstream target genes 30.00 µM SNU-398 Homo sapiens
XZH-5 RT-PCR Influence on expression of proteins downstream target genes 30.00 µM HepG2 Homo sapiens
XZH-5 RT-PCR Influence on expression of proteins downstream target genes 40.00 µM Huh-7 Homo sapiens
XZH-5 RT-PCR Influence on expression of proteins downstream target genes 30.00 µM SNU-387 Homo sapiens
XZH-5 RT-PCR Influence on expression of proteins downstream target genes 30.00 µM SNU-398 Homo sapiens
XZH-5 RT-PCR Influence on expression of proteins downstream target genes 30.00 µM HepG2 Homo sapiens
XZH-5 RT-PCR Influence on expression of proteins downstream target genes 40.00 µM Huh-7 Homo sapiens
XZH-5 RT-PCR Influence on expression of proteins downstream target genes 30.00 µM SNU-387 Homo sapiens
XZH-5 RT-PCR Influence on expression of proteins downstream target genes 30.00 µM SNU-398 Homo sapiens
XZH-5 RT-PCR Influence on expression of proteins downstream target genes 30.00 µM HepG2 Homo sapiens
XZH-5 RT-PCR Influence on expression of proteins downstream target genes 40.00 µM Huh-7 Homo sapiens
XZH-5 RT-PCR Influence on expression of proteins downstream target genes 30.00 µM SNU-387 Homo sapiens
XZH-5 RT-PCR Influence on expression of proteins downstream target genes 30.00 µM SNU-398 Homo sapiens
XZH-5 RT-PCR Influence on expression of proteins downstream target genes 30.00 µM HepG2 Homo sapiens
XZH-5 RT-PCR Influence on expression of proteins downstream target genes 40.00 µM Huh-7 Homo sapiens
XZH-5 RT-PCR Influence on expression of proteins downstream target genes 30.00 µM SNU-387 Homo sapiens
XZH-5 RT-PCR Influence on expression of proteins downstream target genes 30.00 µM SNU-398 Homo sapiens
XZH-5 RT-PCR Influence on expression of proteins downstream target genes 30.00 µM HepG2 Homo sapiens
XZH-5 RT-PCR Influence on expression of proteins downstream target genes 40.00 µM Huh-7 Homo sapiens
XZH-5 RT-PCR Influence on expression of proteins downstream target genes 30.00 µM SNU-387 Homo sapiens
XZH-5 RT-PCR Influence on expression of proteins downstream target genes 30.00 µM SNU-398 Homo sapiens
XZH-5 RT-PCR Influence on expression of proteins downstream target genes 30.00 µM HepG2 Homo sapiens
XZH-5 RT-PCR Influence on expression of proteins downstream target genes 40.00 µM Huh-7 Homo sapiens
XZH-5 Western Blot Influence on protein activity 30.00 µM SNU-387 Homo sapiens
XZH-5 Western Blot Influence on protein activity 30.00 µM SNU-398 Homo sapiens
XZH-5 Western Blot Influence on protein activity 30.00 µM HepG2 Homo sapiens
XZH-5 Western Blot Influence on protein activity 40.00 µM Huh-7 Homo sapiens
XZH-5 Western Blot Influence on protein activity 30.00 µM SNU-387 Homo sapiens
XZH-5 Western Blot Influence on protein activity 30.00 µM SNU-398 Homo sapiens
XZH-5 Western Blot Influence on protein activity 30.00 µM HepG2 Homo sapiens
XZH-5 Western Blot Influence on protein activity 40.00 µM Huh-7 Homo sapiens
XZH-5 Western Blot Influence on cell apoptosis 30.00 µM SNU-387 Homo sapiens
XZH-5 Western Blot Influence on cell apoptosis 30.00 µM SNU-398 Homo sapiens
XZH-5 Western Blot Influence on cell apoptosis 30.00 µM HepG2 Homo sapiens
XZH-5 Western Blot Influence on cell apoptosis 40.00 µM Huh-7 Homo sapiens
XZH-5 Western Blot Influence on cell apoptosis 30.00 µM SNU-387 Homo sapiens
XZH-5 Western Blot Influence on cell apoptosis 30.00 µM SNU-398 Homo sapiens
XZH-5 Western Blot Influence on cell apoptosis 30.00 µM HepG2 Homo sapiens
XZH-5 Western Blot Influence on cell apoptosis 40.00 µM Huh-7 Homo sapiens
XZH-5 Western Blot Influence on cell apoptosis 30.00 µM SNU-387 Homo sapiens
XZH-5 Western Blot Influence on cell apoptosis 30.00 µM SNU-398 Homo sapiens
XZH-5 Western Blot Influence on cell apoptosis 30.00 µM HepG2 Homo sapiens
XZH-5 Western Blot Influence on cell apoptosis 40.00 µM Huh-7 Homo sapiens
XZH-5 Western Blot Influence on cell apoptosis 30.00 µM SNU-387 Homo sapiens
XZH-5 Western Blot Influence on cell apoptosis 30.00 µM SNU-398 Homo sapiens
XZH-5 Western Blot Influence on cell apoptosis 30.00 µM HepG2 Homo sapiens
XZH-5 Western Blot Influence on cell apoptosis 40.00 µM Huh-7 Homo sapiens
XZH-5 Caspase 3/7 assay Influence on cell apoptosis 30.00 µM SNU-387 Homo sapiens
XZH-5 Caspase 3/7 assay Influence on cell apoptosis 30.00 µM SNU-398 Homo sapiens
XZH-5 Caspase 3/7 assay Influence on cell apoptosis 30.00 µM HepG2 Homo sapiens
XZH-5 Caspase 3/7 assay Influence on cell apoptosis 40.00 µM Huh-7 Homo sapiens
XZH-5 Western Blot Influence on protein activity in presence of IL-6 20.00 µM Hep3B Homo sapiens p-STAT3 (Y705)
XZH-5 Western Blot Influence on protein activity in presence of IL-6 30.00 µM Hep3B Homo sapiens p-STAT3 (Y705)
XZH-5 Western Blot Influence on protein activity in presence of IL-6 20.00 µM Hep3B Homo sapiens STAT3
XZH-5 Western Blot Influence on protein activity in presence of IL-6 30.00 µM Hep3B Homo sapiens STAT3
XZH-5 Western Blot Influence on protein activity in presence of IL-6 20.00 µM Hep3B Homo sapiens
XZH-5 Western Blot Influence on protein activity in presence of IL-6 30.00 µM Hep3B Homo sapiens
XZH-5 Western Blot Influence on protein activity in presence of IFNγ 20.00 µM Hep3B Homo sapiens p-STAT3 (Y705)
XZH-5 Western Blot Influence on protein activity in presence of IFNγ 30.00 µM Hep3B Homo sapiens p-STAT3 (Y705)
XZH-5 Western Blot Influence on protein activity in presence of IFNγ 20.00 µM Hep3B Homo sapiens STAT3
XZH-5 Western Blot Influence on protein activity in presence of IFNγ 30.00 µM Hep3B Homo sapiens STAT3
XZH-5 Western Blot Influence on protein activity in presence of IFNγ 20.00 µM Hep3B Homo sapiens
XZH-5 Western Blot Influence on protein activity in presence of IFNγ 30.00 µM Hep3B Homo sapiens
XZH-5 Western Blot Influence on protein activity in presence of IL-6 20.00 µM Hep3B Homo sapiens
XZH-5 Western Blot Influence on protein activity in presence of IL-6 30.00 µM Hep3B Homo sapiens
XZH-5 Western Blot Influence on protein activity in presence of IL-6 20.00 µM Hep3B Homo sapiens
XZH-5 Western Blot Influence on protein activity in presence of IL-6 30.00 µM Hep3B Homo sapiens
XZH-5 Western Blot Influence on protein activity in presence of IL-6 20.00 µM Hep3B Homo sapiens
XZH-5 Western Blot Influence on protein activity in presence of IL-6 30.00 µM Hep3B Homo sapiens
XZH-5 Immunostaining Influence on protein translocation in presence of IL-6 30.00 µM Hep3B Homo sapiens STAT3
XZH-5 Colony formation assay Influence on cell motility 30.00 µM SNU-398 Homo sapiens
XZH-5 CyQUANT Influence on cell viability 30.00 µM HH Homo sapiens
XZH-5 CyQUANT Influence on cell viability 40.00 µM HH Homo sapiens
XZH-5 CyQUANT Influence on cell viability 30.00 µM Hep3B Homo sapiens
XZH-5 CyQUANT Influence on cell viability 40.00 µM Hep3B Homo sapiens
XZH-5 CyQUANT Influence on cell viability 30.00 µM SNU-398 Homo sapiens
XZH-5 CyQUANT Influence on cell viability 40.00 µM SNU-398 Homo sapiens
XZH-5 CyQUANT Influence on cell viability 30.00 µM HepG2 Homo sapiens
XZH-5 CyQUANT Influence on cell viability 40.00 µM HepG2 Homo sapiens
XZH-5 CyQUANT Influence on cell viability 30.00 µM Huh-7 Homo sapiens
XZH-5 CyQUANT Influence on cell viability 40.00 µM Huh-7 Homo sapiens
XZH-5 CyQUANT Influence on cell viability 30.00 µM SNU-387 Homo sapiens
XZH-5 CyQUANT Influence on cell viability 40.00 µM SNU-387 Homo sapiens
XZH-5 Western Blot Influence on protein activity 30.00 µM MDA-MB-231 Homo sapiens p-STAT3 (Y705)
XZH-5 Western Blot Influence on protein activity 40.00 µM MDA-MB-231 Homo sapiens p-STAT3 (Y705)
XZH-5 Western Blot Influence on protein activity 50.00 µM MDA-MB-231 Homo sapiens p-STAT3 (Y705)
XZH-5 Western Blot Influence on protein activity 30.00 µM SUM 159 Homo sapiens p-STAT3 (Y705)
XZH-5 Western Blot Influence on protein activity 40.00 µM SUM 159 Homo sapiens p-STAT3 (Y705)
XZH-5 Western Blot Influence on protein activity 50.00 µM SUM 159 Homo sapiens p-STAT3 (Y705)
XZH-5 Western Blot Influence on protein activity 25.00 µM Panc-1 Homo sapiens p-STAT3 (Y705)
XZH-5 Western Blot Influence on protein activity 50.00 µM Panc-1 Homo sapiens p-STAT3 (Y705)
XZH-5 Western Blot Influence on protein activity 25.00 µM SW1990 Homo sapiens p-STAT3 (Y705)
XZH-5 Western Blot Influence on protein activity 50.00 µM SW1990 Homo sapiens p-STAT3 (Y705)
XZH-5 Western Blot Influence on protein activity 30.00 µM MDA-MB-231 Homo sapiens STAT3
XZH-5 Western Blot Influence on protein activity 40.00 µM MDA-MB-231 Homo sapiens STAT3
XZH-5 Western Blot Influence on protein activity 50.00 µM MDA-MB-231 Homo sapiens STAT3
XZH-5 Western Blot Influence on protein activity 30.00 µM SUM 159 Homo sapiens STAT3
XZH-5 Western Blot Influence on protein activity 40.00 µM SUM 159 Homo sapiens STAT3
XZH-5 Western Blot Influence on protein activity 50.00 µM SUM 159 Homo sapiens STAT3
XZH-5 Western Blot Influence on protein activity 25.00 µM Panc-1 Homo sapiens STAT3
XZH-5 Western Blot Influence on protein activity 50.00 µM Panc-1 Homo sapiens STAT3
XZH-5 Western Blot Influence on protein activity 25.00 µM SW1990 Homo sapiens STAT3
XZH-5 Western Blot Influence on protein activity 50.00 µM SW1990 Homo sapiens STAT3
XZH-5 Western Blot Influence on protein activity 30.00 µM MDA-MB-231 Homo sapiens
XZH-5 Western Blot Influence on protein activity 40.00 µM MDA-MB-231 Homo sapiens
XZH-5 Western Blot Influence on protein activity 50.00 µM MDA-MB-231 Homo sapiens
XZH-5 Western Blot Influence on protein activity 30.00 µM SUM 159 Homo sapiens
XZH-5 Western Blot Influence on protein activity 40.00 µM SUM 159 Homo sapiens
XZH-5 Western Blot Influence on protein activity 50.00 µM SUM 159 Homo sapiens
XZH-5 Western Blot Influence on protein activity 25.00 µM Panc-1 Homo sapiens
XZH-5 Western Blot Influence on protein activity 50.00 µM Panc-1 Homo sapiens
XZH-5 Western Blot Influence on protein activity 25.00 µM SW1990 Homo sapiens
XZH-5 Western Blot Influence on protein activity 50.00 µM SW1990 Homo sapiens
XZH-5 RT-PCR Influence on expression of proteins downstream target genes 50.00 µM MDA-MB-231 Homo sapiens
XZH-5 RT-PCR Influence on expression of proteins downstream target genes 50.00 µM SUM 159 Homo sapiens
XZH-5 RT-PCR Influence on expression of proteins downstream target genes 50.00 µM Panc-1 Homo sapiens
XZH-5 RT-PCR Influence on expression of proteins downstream target genes 50.00 µM SW1990 Homo sapiens
XZH-5 RT-PCR Influence on expression of proteins downstream target genes 50.00 µM MDA-MB-231 Homo sapiens
XZH-5 RT-PCR Influence on expression of proteins downstream target genes 50.00 µM SUM 159 Homo sapiens
XZH-5 RT-PCR Influence on expression of proteins downstream target genes 50.00 µM Panc-1 Homo sapiens
XZH-5 RT-PCR Influence on expression of proteins downstream target genes 50.00 µM SW1990 Homo sapiens
XZH-5 RT-PCR Influence on expression of proteins downstream target genes 50.00 µM MDA-MB-231 Homo sapiens
XZH-5 RT-PCR Influence on expression of proteins downstream target genes 50.00 µM SUM 159 Homo sapiens
XZH-5 RT-PCR Influence on expression of proteins downstream target genes 50.00 µM Panc-1 Homo sapiens
XZH-5 RT-PCR Influence on expression of proteins downstream target genes 50.00 µM SW1990 Homo sapiens
XZH-5 RT-PCR Influence on expression of proteins downstream target genes 50.00 µM MDA-MB-231 Homo sapiens
XZH-5 RT-PCR Influence on expression of proteins downstream target genes 50.00 µM SUM 159 Homo sapiens
XZH-5 RT-PCR Influence on expression of proteins downstream target genes 50.00 µM Panc-1 Homo sapiens
XZH-5 RT-PCR Influence on expression of proteins downstream target genes 50.00 µM SW1990 Homo sapiens
XZH-5 RT-PCR Influence on expression of proteins downstream target genes 50.00 µM MDA-MB-231 Homo sapiens
XZH-5 RT-PCR Influence on expression of proteins downstream target genes 50.00 µM SUM 159 Homo sapiens
XZH-5 RT-PCR Influence on expression of proteins downstream target genes 50.00 µM Panc-1 Homo sapiens
XZH-5 RT-PCR Influence on expression of proteins downstream target genes 50.00 µM SW1990 Homo sapiens
XZH-5 Western Blot Influence on cell apoptosis 50.00 µM MDA-MB-231 Homo sapiens
XZH-5 Western Blot Influence on cell apoptosis 50.00 µM SUM 159 Homo sapiens
XZH-5 Western Blot Influence on cell apoptosis 50.00 µM Panc-1 Homo sapiens
XZH-5 Western Blot Influence on cell apoptosis 50.00 µM SW1990 Homo sapiens
XZH-5 Western Blot Influence on cell apoptosis 50.00 µM MDA-MB-231 Homo sapiens
XZH-5 Western Blot Influence on cell apoptosis 50.00 µM SUM 159 Homo sapiens
XZH-5 Western Blot Influence on cell apoptosis 50.00 µM Panc-1 Homo sapiens
XZH-5 Western Blot Influence on cell apoptosis 50.00 µM SW1990 Homo sapiens
XZH-5 Western Blot Influence on cell apoptosis 50.00 µM MDA-MB-231 Homo sapiens
XZH-5 Western Blot Influence on cell apoptosis 50.00 µM SUM 159 Homo sapiens
XZH-5 Western Blot Influence on cell apoptosis 50.00 µM Panc-1 Homo sapiens
XZH-5 Western Blot Influence on cell apoptosis 50.00 µM SW1990 Homo sapiens
XZH-5 Caspase 3/7 assay Influence on cell apoptosis 50.00 µM MDA-MB-231 Homo sapiens
XZH-5 Caspase 3/7 assay Influence on cell apoptosis 50.00 µM SUM 159 Homo sapiens
XZH-5 Caspase 3/7 assay Influence on cell apoptosis 50.00 µM Panc-1 Homo sapiens
XZH-5 Caspase 3/7 assay Influence on cell apoptosis 50.00 µM SW1990 Homo sapiens
XZH-5 Western Blot Influence on protein activity in presence of IL-6 25.00 µM MCF-7 Homo sapiens p-STAT3 (Y705)
XZH-5 Western Blot Influence on protein activity in presence of IL-6 50.00 µM MCF-7 Homo sapiens p-STAT3 (Y705)
XZH-5 Western Blot Influence on protein activity in presence of IL-6 25.00 µM AsPC-1 Homo sapiens p-STAT3 (Y705)
XZH-5 Western Blot Influence on protein activity in presence of IL-6 50.00 µM AsPC-1 Homo sapiens p-STAT3 (Y705)
XZH-5 Western Blot Influence on protein activity in presence of IL-6 25.00 µM MCF-7 Homo sapiens STAT3
XZH-5 Western Blot Influence on protein activity in presence of IL-6 50.00 µM MCF-7 Homo sapiens STAT3
XZH-5 Western Blot Influence on protein activity in presence of IL-6 25.00 µM AsPC-1 Homo sapiens STAT3
XZH-5 Western Blot Influence on protein activity in presence of IL-6 50.00 µM AsPC-1 Homo sapiens STAT3
XZH-5 Western Blot Influence on protein activity in presence of IL-6 25.00 µM MCF-7 Homo sapiens
XZH-5 Western Blot Influence on protein activity in presence of IL-6 50.00 µM MCF-7 Homo sapiens
XZH-5 Western Blot Influence on protein activity in presence of IL-6 25.00 µM AsPC-1 Homo sapiens
XZH-5 Western Blot Influence on protein activity in presence of IL-6 50.00 µM AsPC-1 Homo sapiens
XZH-5 Western Blot Influence on protein activity in presence of IFNγ 25.00 µM MCF-7 Homo sapiens p-STAT1 (Y701)
XZH-5 Western Blot Influence on protein activity in presence of IFNγ 50.00 µM MCF-7 Homo sapiens p-STAT1 (Y701)
XZH-5 Western Blot Influence on protein activity in presence of IFNγ 25.00 µM AsPC-1 Homo sapiens p-STAT1 (Y701)
XZH-5 Western Blot Influence on protein activity in presence of IFNγ 50.00 µM AsPC-1 Homo sapiens p-STAT1 (Y701)
XZH-5 Western Blot Influence on protein activity in presence of IFNγ 25.00 µM MCF-7 Homo sapiens STAT1
XZH-5 Western Blot Influence on protein activity in presence of IFNγ 50.00 µM MCF-7 Homo sapiens STAT1
XZH-5 Western Blot Influence on protein activity in presence of IFNγ 25.00 µM AsPC-1 Homo sapiens STAT1
XZH-5 Western Blot Influence on protein activity in presence of IFNγ 50.00 µM AsPC-1 Homo sapiens STAT1
XZH-5 Western Blot Influence on protein activity in presence of IFNγ 25.00 µM MCF-7 Homo sapiens
XZH-5 Western Blot Influence on protein activity in presence of IFNγ 50.00 µM MCF-7 Homo sapiens
XZH-5 Western Blot Influence on protein activity in presence of IFNγ 25.00 µM AsPC-1 Homo sapiens
XZH-5 Western Blot Influence on protein activity in presence of IFNγ 50.00 µM AsPC-1 Homo sapiens
XZH-5 Immunofluorescence Influence on protein translocation in presence of IL-6 50.00 µM MCF-7 Homo sapiens p-STAT3
XZH-5 Immunofluorescence Influence on protein translocation in presence of IL-6 50.00 µM MCF-7 Homo sapiens STAT3
XZH-5 Colony formation assay Influence on cell motility 30.00 µM MDA-MB-231 Homo sapiens
XZH-5 Colony formation assay Influence on cell motility 40.00 µM MDA-MB-231 Homo sapiens
XZH-5 Colony formation assay Influence on cell motility 25.00 µM Panc-1 Homo sapiens
XZH-5 Colony formation assay Influence on cell motility 50.00 µM Panc-1 Homo sapiens
XZH-5 Wound healing assay Influence on cell motility 30.00 µM MDA-MB-231 Homo sapiens
XZH-5 Wound healing assay Influence on cell motility 40.00 µM MDA-MB-231 Homo sapiens
XZH-5 Wound healing assay Influence on cell motility 25.00 µM Panc-1 Homo sapiens
XZH-5 Wound healing assay Influence on cell motility 50.00 µM Panc-1 Homo sapiens
XZH-5 CyQUANT Influence on cell viability 15.00 µM MDA-MB-231 Homo sapiens
XZH-5 CyQUANT Influence on cell viability 20.00 µM MDA-MB-231 Homo sapiens
XZH-5 CyQUANT Influence on cell viability 15.00 µM Panc-1 Homo sapiens
XZH-5 CyQUANT Influence on cell viability 20.00 µM Panc-1 Homo sapiens
XZH-5 CyQUANT Influence on cell viability in presence of chemiterapeutic 15.00 µM MDA-MB-231 Homo sapiens
XZH-5 CyQUANT Influence on cell viability in presence of chemiterapeutic 20.00 µM MDA-MB-231 Homo sapiens
XZH-5 CyQUANT Influence on cell viability in presence of chemiterapeutic 15.00 µM Panc-1 Homo sapiens
XZH-5 CyQUANT Influence on cell viability in presence of chemiterapeutic 20.00 µM Panc-1 Homo sapiens