| STATTIC |
Influence on gene expression in precence of IFNα |
RT-qPCR |
10.00 µM |
HMEC |
Homo sapiens |
|
|
|
| STATTIC |
Influence on gene expression in precence of IFNα |
RT-qPCR |
5.00 µM |
HMEC |
Homo sapiens |
|
|
|
| STATTIC |
Influence on gene expression in precence of IFNα |
RT-qPCR |
2.50 µM |
HMEC |
Homo sapiens |
|
|
|
| STATTIC |
Influence on gene expression in precence of IFNα |
RT-qPCR |
10.00 µM |
HMEC |
Homo sapiens |
|
|
|
| STATTIC |
Influence on gene expression in precence of IFNα |
RT-qPCR |
5.00 µM |
HMEC |
Homo sapiens |
|
|
|
| STATTIC |
Influence on gene expression in precence of IFNα |
RT-qPCR |
2.50 µM |
HMEC |
Homo sapiens |
|
|
|
| STATTIC |
Influence on gene expression in precence of IFNα |
RT-qPCR |
10.00 µM |
HMEC |
Homo sapiens |
|
|
|
| STATTIC |
Influence on gene expression in precence of IFNα |
RT-qPCR |
5.00 µM |
HMEC |
Homo sapiens |
|
|
|
| STATTIC |
Influence on gene expression in precence of IFNα |
RT-qPCR |
2.50 µM |
HMEC |
Homo sapiens |
|
|
|
| STATTIC |
Influence on gene expression in precence of IFNα |
RT-qPCR |
10.00 µM |
HMEC |
Homo sapiens |
|
|
|
| STATTIC |
Influence on gene expression in precence of IFNα |
RT-qPCR |
5.00 µM |
HMEC |
Homo sapiens |
|
|
|
| STATTIC |
Influence on gene expression in precence of IFNα |
RT-qPCR |
2.50 µM |
HMEC |
Homo sapiens |
|
|
|
| STATTIC |
Influence on gene expression in precence of IFNγLPS |
RT-qPCR |
10.00 µM |
HMEC |
Homo sapiens |
|
|
|
| STATTIC |
Influence on gene expression in precence of IFNγLPS |
RT-qPCR |
5.00 µM |
HMEC |
Homo sapiens |
|
|
|
| STATTIC |
Influence on gene expression in precence of IFNγLPS |
RT-qPCR |
2.50 µM |
HMEC |
Homo sapiens |
|
|
|
| STATTIC |
Influence on gene expression in precence of IFNγLPS |
RT-qPCR |
10.00 µM |
HMEC |
Homo sapiens |
|
|
|
| STATTIC |
Influence on gene expression in precence of IFNγLPS |
RT-qPCR |
5.00 µM |
HMEC |
Homo sapiens |
|
|
|
| STATTIC |
Influence on gene expression in precence of IFNγLPS |
RT-qPCR |
2.50 µM |
HMEC |
Homo sapiens |
|
|
|
| STATTIC |
Influence on gene expression in precence of IFNγLPS |
RT-qPCR |
10.00 µM |
HMEC |
Homo sapiens |
|
|
|
| STATTIC |
Influence on gene expression in precence of IFNγLPS |
RT-qPCR |
5.00 µM |
HMEC |
Homo sapiens |
|
|
|
| STATTIC |
Influence on gene expression in precence of IFNγLPS |
RT-qPCR |
2.50 µM |
HMEC |
Homo sapiens |
|
|
|
| STATTIC |
Influence on gene expression in precence of IFNγLPS |
RT-qPCR |
10.00 µM |
HMEC |
Homo sapiens |
|
|
|
| STATTIC |
Influence on gene expression in precence of IFNγLPS |
RT-qPCR |
5.00 µM |
HMEC |
Homo sapiens |
|
|
|
| STATTIC |
Influence on gene expression in precence of IFNγLPS |
RT-qPCR |
2.50 µM |
HMEC |
Homo sapiens |
|
|
|
| STATTIC |
Influence on gene expression in precence of IFNγLPS |
RT-qPCR |
10.00 µM |
HMEC |
Homo sapiens |
|
|
|
| STATTIC |
Influence on gene expression in precence of IFNγLPS |
RT-qPCR |
5.00 µM |
HMEC |
Homo sapiens |
|
|
|
| STATTIC |
Influence on gene expression in precence of IFNγLPS |
RT-qPCR |
2.50 µM |
HMEC |
Homo sapiens |
|
|
|
| STATTIC |
Influence on gene expression in precence of IFNγLPS |
RT-qPCR |
10.00 µM |
HMEC |
Homo sapiens |
|
|
|
| STATTIC |
Influence on gene expression in precence of IFNγLPS |
RT-qPCR |
5.00 µM |
HMEC |
Homo sapiens |
|
|
|
| STATTIC |
Influence on gene expression in precence of IFNγLPS |
RT-qPCR |
2.50 µM |
HMEC |
Homo sapiens |
|
|
|
| STATTIC |
Influence on gene expression in precence of IFNγLPS |
RT-qPCR |
10.00 µM |
HMEC |
Homo sapiens |
|
|
|
| STATTIC |
Influence on gene expression in precence of IFNγLPS |
RT-qPCR |
5.00 µM |
HMEC |
Homo sapiens |
|
|
|
| STATTIC |
Influence on gene expression in precence of IFNγLPS |
RT-qPCR |
2.50 µM |
HMEC |
Homo sapiens |
|
|
|
| STATTIC |
Influence on cell motility in precence of IFNγLPS |
Wound healing assay |
10.00 µM |
HMEC |
Homo sapiens |
|
|
|
| STATTIC |
Influence on cell motility in precence of IFNγLPS |
Adhesion assay |
1.00 µM |
HUVECS |
Homo sapiens |
|
|
|
| STATTIC |
Influence on cell motility in precence of IFNγLPS |
Adhesion assay |
5.00 µM |
HUVECS |
Homo sapiens |
|
|
|
| STATTIC |
Influence on artery contractility in precence of IFNγLPS and noradrenaline |
Constriction assay |
1.00 nM |
mesenteric artery |
Mus musculus |
|
|
|
| Tocilizumab |
Influence on tumor growth |
Tumor volume |
5.00 mg/kg |
UM-HMC-3B (xenograft) |
Mus musculus |
C.B-17 scid |
p-STAT3 |
|
| Tocilizumab |
Influence on tumor growth |
Mouse weight |
5.00 mg/kg |
UM-HMC-3B (xenograft) |
Mus musculus |
C.B-17 scid |
STAT3 |
|
| Tocilizumab |
Influence on tumor growth |
Survival Rate |
5.00 mg/kg |
UM-HMC-3B (xenograft) |
Mus musculus |
C.B-17 scid |
|
|
| Tocilizumab |
Influence on protein activity in tumor tissue |
Western Blot |
5.00 mg/kg |
UM-HMC-3B (xenograft) |
Mus musculus |
C.B-17 scid |
|
|
| Tocilizumab |
Influence on protein activity in tumor tissue |
Western Blot |
5.00 mg/kg |
UM-HMC-3B (xenograft) |
Mus musculus |
C.B-17 scid |
|
|
| Tocilizumab |
Influence on protein activity in tumor tissue |
Western Blot |
5.00 mg/kg |
UM-HMC-3B (xenograft) |
Mus musculus |
C.B-17 scid |
|
|
| Tocilizumab |
Influence on protein activity in tumor tissue |
Western Blot |
5.00 mg/kg |
UM-HMC-3B (xenograft) |
Mus musculus |
C.B-17 scid |
|
|
| Tocilizumab |
Influence on cell viability |
SRB assay |
0.01 µM |
UM-HMC-1 |
Homo sapiens |
|
|
|
| Tocilizumab |
Influence on cell viability |
SRB assay |
0.01 µM |
UM-HMC-3A |
Homo sapiens |
|
|
|
| Tocilizumab |
Influence on cell viability |
SRB assay |
0.01 µM |
UM-HMC-3B |
Homo sapiens |
|
|
|
| Tocilizumab |
Influence on cell viability |
SRB assay |
0.01 µM |
HDMEC |
Homo sapiens |
|
|
|
| Tocilizumab |
Influence on cell viability |
SRB assay |
0.10 µM |
UM-HMC-1 |
Homo sapiens |
|
|
|
| Tocilizumab |
Influence on cell viability |
SRB assay |
0.10 µM |
UM-HMC-3A |
Homo sapiens |
|
|
|
