STATTIC

Name Value
Weight 211.198 g/mol
Zinc ID ZINC162014
Smiles O=[N+]([O-])c1ccc2c(c1)S(=O)(=O)C=C2
Molecular formula C8H5NO4S
Mode of inhibition Direct STAT; Non-peptide small molecule
CAS 19983-44-9

Clinical Trials

Study title Status Conditions Link

Visualization

References

Publication DOI Pubmed PMCID
Stat3 Inhibitor Stattic Exhibits Potent Antitumor Activity and Induces Chemo- and Radio-Sensitivity in Nasopharyngeal Carcinoma 10.1371/journal.pone.0054565 N/A N/A
Stattic: A Small-Molecule Inhibitor of STAT3 Activation and Dimerization 10.1016/j.chembiol.2006.09.018 N/A N/A

Vendors

Company Lnk to product
Selleckchem https://www.selleckchem.com/products/stattic.html
Sigma Aldrich https://www.sigmaaldrich.com/catalog/product/sigma/s7947?lang=pl&region=PL
Abcam https://www.abcam.com/stattic-stat3-inhibitor-ab120952.html
MedChemExpress https://www.medchemexpress.com/Stattic.html
Tocris https://www.tocris.com/products/stattic_2798
Enzolifesciences https://www.enzolifesciences.com/BML-EI368/stattic/
Santa Cruz Biotechnology https://www.scbt.com/p/stat3-inhibitor-v-stattic-19983-44-9
Caymanchemical https://www.caymanchem.com/product/14590/stattic
Rndsystems https://www.rndsystems.com/products/stattic_2798
APExBIO https://www.apexbt.com/stattic.html
MERCK (Sigma Aldrich) https://www.merckmillipore.com/PL/pl/product/STAT3-Inhibitor-V-Stattic-CAS-19983-44-9-Calbiochem,EMD_BIO-573099?ReferrerURL=https%3A%2F%2Fwww.google.com%2F&bd=1
Axon Medchem https://www.axonmedchem.com/product/2314

Filter data

Compound STATTIC
Experiment types Adhesion assay, Colony Formation , Constriction assay , EMSA, Flow cytometry , Fluorescence polarization, Hoechst 33342 staining, Immunofluorescce, MTT, PI staining , RT-qPCR, TUNEL, Western Blot, Wound healing assay
Concentrations 0.01, 0.25, 0.50, 1.00, 10.00, 100.00, 15.00, 150.00, 2.00, 2.50, 20.00, 200.00, 250.00, 4.00, 5.00, 50.00, 6.00, 8.00, N/A
Cell lines C666-1, CNE1, CNE2, HMEC, HONE1, HUVECS, HepG2, MDA-MB-231, MDA-MB-435, MDA-MB-435S, mesenteric artery
Organisms Homo sapiens, Mus musculus
Animal models
STAT proteins STAT1, STAT1:STAT1, STAT2, STAT3, STAT3:STAT1, STAT3:STAT3, STAT5B, p-STAT1, p-STAT2, p-STAT3, p-STAT3(Y705)
Other AKT, Actin, CCL5, CXCL10, CXCL9, Caspase 3 , Caspase-3, Caspase-3 , Cleaved Caspase 3, Cleaved Caspase-3, Cleaved PARP, Cyclin D1, ERK1/2, ICAM, IFIT2, IRF1, JAK1, JAK2, JNK, OAS2, PARP, SOCS3, VCAM, p-AKT, p-ERK1/2, p-JAK1, p-JAK2, p-JNK, p-SRC, tubulin, α-tubulin, β-actin

Experiments

Compound Experiment type Investigated event Concentration Cell line Organism Animal model Stat protein Details
STATTIC Western Blot Influence on protein activity in presence of IL-6 20.00 µM CNE1 Homo sapiens p-STAT3(Y705)
STATTIC Western Blot Influence on protein activity in presence of IL-6 20.00 µM CNE1 Homo sapiens STAT3
STATTIC Western Blot Influence on protein activity in presence of IL-6 20.00 µM CNE1 Homo sapiens
STATTIC Western Blot Influence on protein activity in presence of IL-6 20.00 µM CNE2 Homo sapiens p-STAT3(Y705)
STATTIC Western Blot Influence on protein activity in presence of IL-6 20.00 µM CNE2 Homo sapiens STAT3
STATTIC Western Blot Influence on protein activity in presence of IL-6 20.00 µM CNE2 Homo sapiens
STATTIC Western Blot Influence on protein activity in presence of IL-6 20.00 µM HONE1 Homo sapiens p-STAT3(Y705)
STATTIC Western Blot Influence on protein activity in presence of IL-6 20.00 µM HONE1 Homo sapiens STAT3
STATTIC Western Blot Influence on protein activity in presence of IL-6 20.00 µM HONE1 Homo sapiens
STATTIC Western Blot Influence on protein activity 2.50 µM CNE1 Homo sapiens p-STAT3(Y705)
STATTIC Western Blot Influence on protein activity 5.00 µM CNE1 Homo sapiens p-STAT3(Y705)
STATTIC Western Blot Influence on protein activity 10.00 µM CNE1 Homo sapiens p-STAT3(Y705)
STATTIC Western Blot Influence on protein activity 2.50 µM CNE2 Homo sapiens p-STAT3(Y705)
STATTIC Western Blot Influence on protein activity 5.00 µM CNE2 Homo sapiens p-STAT3(Y705)
STATTIC Western Blot Influence on protein activity 10.00 µM CNE2 Homo sapiens p-STAT3(Y705)
STATTIC Western Blot Influence on protein activity 2.50 µM HONE1 Homo sapiens p-STAT3(Y705)
STATTIC Western Blot Influence on protein activity 5.00 µM HONE1 Homo sapiens p-STAT3(Y705)
STATTIC Western Blot Influence on protein activity 10.00 µM HONE1 Homo sapiens p-STAT3(Y705)
STATTIC Western Blot Influence on protein activity 2.50 µM CNE1 Homo sapiens STAT3
STATTIC Western Blot Influence on protein activity 5.00 µM CNE1 Homo sapiens STAT3
STATTIC Western Blot Influence on protein activity 10.00 µM CNE1 Homo sapiens STAT3
STATTIC Western Blot Influence on protein activity 2.50 µM CNE2 Homo sapiens STAT3
STATTIC Western Blot Influence on protein activity 5.00 µM CNE2 Homo sapiens STAT3
STATTIC Western Blot Influence on protein activity 10.00 µM CNE2 Homo sapiens STAT3
STATTIC Western Blot Influence on protein activity 2.50 µM HONE1 Homo sapiens STAT3
STATTIC Western Blot Influence on protein activity 5.00 µM HONE1 Homo sapiens STAT3
STATTIC Western Blot Influence on protein activity 10.00 µM HONE1 Homo sapiens STAT3
STATTIC Western Blot Influence on protein activity 2.50 µM CNE1 Homo sapiens
STATTIC Western Blot Influence on protein activity 5.00 µM CNE1 Homo sapiens
STATTIC Western Blot Influence on protein activity 10.00 µM CNE1 Homo sapiens
STATTIC Western Blot Influence on protein activity 2.50 µM CNE2 Homo sapiens
STATTIC Western Blot Influence on protein activity 5.00 µM CNE2 Homo sapiens
STATTIC Western Blot Influence on protein activity 10.00 µM CNE2 Homo sapiens
STATTIC Western Blot Influence on protein activity 2.50 µM HONE1 Homo sapiens
STATTIC Western Blot Influence on protein activity 5.00 µM HONE1 Homo sapiens
STATTIC Western Blot Influence on protein activity 10.00 µM HONE1 Homo sapiens
STATTIC Western Blot Influence on protein activity 2.50 µM CNE1 Homo sapiens
STATTIC Western Blot Influence on protein activity 5.00 µM CNE1 Homo sapiens
STATTIC Western Blot Influence on protein activity 10.00 µM CNE1 Homo sapiens
STATTIC Western Blot Influence on protein activity 2.50 µM CNE2 Homo sapiens
STATTIC Western Blot Influence on protein activity 5.00 µM CNE2 Homo sapiens
STATTIC Western Blot Influence on protein activity 10.00 µM CNE2 Homo sapiens
STATTIC Western Blot Influence on protein activity 2.50 µM HONE1 Homo sapiens
STATTIC Western Blot Influence on protein activity 5.00 µM HONE1 Homo sapiens
STATTIC Western Blot Influence on protein activity 10.00 µM HONE1 Homo sapiens
STATTIC MTT Influence on cell viability N/A µM CNE1 Homo sapiens
STATTIC MTT Influence on cell viability N/A µM CNE2 Homo sapiens
STATTIC MTT Influence on cell viability N/A µM HONE1 Homo sapiens
STATTIC MTT Influence on cell viability N/A µM C666-1 Homo sapiens
STATTIC Colony Formation Influence on cell viability 0.25 µM CNE1 Homo sapiens
STATTIC Colony Formation Influence on cell viability 0.50 µM CNE1 Homo sapiens
STATTIC Colony Formation Influence on cell viability 0.25 µM CNE2 Homo sapiens
STATTIC Colony Formation Influence on cell viability 0.50 µM CNE2 Homo sapiens
STATTIC Colony Formation Influence on cell viability 0.25 µM HONE1 Homo sapiens
STATTIC Colony Formation Influence on cell viability 0.50 µM HONE1 Homo sapiens
STATTIC Flow cytometry Influence on apoptosis 5.00 µM CNE1 Homo sapiens
STATTIC Flow cytometry Influence on apoptosis 10.00 µM CNE1 Homo sapiens
STATTIC Flow cytometry Influence on apoptosis 15.00 µM CNE1 Homo sapiens
STATTIC Flow cytometry Influence on apoptosis 5.00 µM CNE2 Homo sapiens
STATTIC Flow cytometry Influence on apoptosis 10.00 µM CNE2 Homo sapiens
STATTIC Flow cytometry Influence on apoptosis 15.00 µM CNE2 Homo sapiens
STATTIC Flow cytometry Influence on apoptosis 5.00 µM HONE1 Homo sapiens
STATTIC Flow cytometry Influence on apoptosis 10.00 µM HONE1 Homo sapiens
STATTIC Flow cytometry Influence on apoptosis 15.00 µM HONE1 Homo sapiens
STATTIC Hoechst 33342 staining Influence on apoptosis 10.00 µM CNE1 Homo sapiens
STATTIC Hoechst 33342 staining Influence on apoptosis 10.00 µM CNE2 Homo sapiens
STATTIC Hoechst 33342 staining Influence on apoptosis 10.00 µM HONE1 Homo sapiens
STATTIC Immunofluorescce Influence on apoptosis 10.00 µM CNE1 Homo sapiens
STATTIC Immunofluorescce Influence on apoptosis 15.00 µM CNE1 Homo sapiens
STATTIC Immunofluorescce Influence on apoptosis 10.00 µM CNE2 Homo sapiens
STATTIC Immunofluorescce Influence on apoptosis 15.00 µM CNE2 Homo sapiens
STATTIC Western Blot Influence on apoptosis 5.00 µM CNE1 Homo sapiens
STATTIC Western Blot Influence on apoptosis 15.00 µM CNE1 Homo sapiens
STATTIC Western Blot Influence on apoptosis 5.00 µM CNE1 Homo sapiens
STATTIC Western Blot Influence on apoptosis 15.00 µM CNE1 Homo sapiens
STATTIC Western Blot Influence on apoptosis 5.00 µM CNE1 Homo sapiens
STATTIC Western Blot Influence on apoptosis 15.00 µM CNE1 Homo sapiens
STATTIC Western Blot Influence on apoptosis 5.00 µM CNE1 Homo sapiens
STATTIC Western Blot Influence on apoptosis 15.00 µM CNE1 Homo sapiens
STATTIC Western Blot Influence on apoptosis 5.00 µM CNE1 Homo sapiens
STATTIC Western Blot Influence on apoptosis 15.00 µM CNE1 Homo sapiens
STATTIC Western Blot Influence on apoptosis 5.00 µM CNE2 Homo sapiens
STATTIC Western Blot Influence on apoptosis 15.00 µM CNE2 Homo sapiens
STATTIC Western Blot Influence on apoptosis 5.00 µM CNE2 Homo sapiens
STATTIC Western Blot Influence on apoptosis 15.00 µM CNE2 Homo sapiens
STATTIC Western Blot Influence on apoptosis 5.00 µM CNE2 Homo sapiens
STATTIC Western Blot Influence on apoptosis 15.00 µM CNE2 Homo sapiens
STATTIC Western Blot Influence on apoptosis 5.00 µM CNE2 Homo sapiens
STATTIC Western Blot Influence on apoptosis 15.00 µM CNE2 Homo sapiens
STATTIC Western Blot Influence on apoptosis 5.00 µM CNE2 Homo sapiens
STATTIC Western Blot Influence on apoptosis 15.00 µM CNE2 Homo sapiens
STATTIC Western Blot Influence on apoptosis 5.00 µM HONE1 Homo sapiens
STATTIC Western Blot Influence on apoptosis 15.00 µM HONE1 Homo sapiens
STATTIC Western Blot Influence on apoptosis 5.00 µM HONE1 Homo sapiens
STATTIC Western Blot Influence on apoptosis 15.00 µM HONE1 Homo sapiens
STATTIC Western Blot Influence on apoptosis 5.00 µM HONE1 Homo sapiens
STATTIC Western Blot Influence on apoptosis 15.00 µM HONE1 Homo sapiens
STATTIC Western Blot Influence on apoptosis 5.00 µM HONE1 Homo sapiens
STATTIC Western Blot Influence on apoptosis 15.00 µM HONE1 Homo sapiens
STATTIC Western Blot Influence on apoptosis 5.00 µM HONE1 Homo sapiens
STATTIC Western Blot Influence on apoptosis 15.00 µM HONE1 Homo sapiens
STATTIC Western Blot Influence on apoptosis 5.00 µM C666-1 Homo sapiens
STATTIC Western Blot Influence on apoptosis 15.00 µM C666-1 Homo sapiens
STATTIC Western Blot Influence on apoptosis 5.00 µM C666-1 Homo sapiens
STATTIC Western Blot Influence on apoptosis 15.00 µM C666-1 Homo sapiens
STATTIC Western Blot Influence on apoptosis 5.00 µM C666-1 Homo sapiens
STATTIC Western Blot Influence on apoptosis 15.00 µM C666-1 Homo sapiens
STATTIC Western Blot Influence on apoptosis 5.00 µM C666-1 Homo sapiens
STATTIC Western Blot Influence on apoptosis 15.00 µM C666-1 Homo sapiens
STATTIC Western Blot Influence on apoptosis 5.00 µM C666-1 Homo sapiens
STATTIC Western Blot Influence on apoptosis 15.00 µM C666-1 Homo sapiens
STATTIC Western Blot Influence on apoptosis in transfected cells 5.00 µM CNE1 Homo sapiens
STATTIC Western Blot Influence on apoptosis in transfected cells 15.00 µM CNE1 Homo sapiens
STATTIC Western Blot Influence on apoptosis in transfected cells 5.00 µM CNE1 Homo sapiens
STATTIC Western Blot Influence on apoptosis in transfected cells 15.00 µM CNE1 Homo sapiens
STATTIC Western Blot Influence on apoptosis in transfected cells 5.00 µM CNE1 Homo sapiens
STATTIC Western Blot Influence on apoptosis in transfected cells 15.00 µM CNE1 Homo sapiens
STATTIC Western Blot Influence on apoptosis in transfected cells 5.00 µM CNE2 Homo sapiens
STATTIC Western Blot Influence on apoptosis in transfected cells 15.00 µM CNE2 Homo sapiens
STATTIC Western Blot Influence on apoptosis in transfected cells 5.00 µM CNE2 Homo sapiens
STATTIC Western Blot Influence on apoptosis in transfected cells 15.00 µM CNE2 Homo sapiens
STATTIC Western Blot Influence on apoptosis in transfected cells 5.00 µM CNE2 Homo sapiens
STATTIC Western Blot Influence on apoptosis in transfected cells 15.00 µM CNE2 Homo sapiens
STATTIC MTT Influence on cisplatin activity 2.00 µM CNE1 Homo sapiens
STATTIC MTT Influence on cisplatin activity 4.00 µM CNE1 Homo sapiens
STATTIC MTT Influence on cisplatin activity 6.00 µM CNE1 Homo sapiens
STATTIC MTT Influence on cisplatin activity 8.00 µM CNE1 Homo sapiens
STATTIC MTT Influence on cisplatin activity 2.00 µM CNE2 Homo sapiens
STATTIC MTT Influence on cisplatin activity 4.00 µM CNE2 Homo sapiens
STATTIC MTT Influence on cisplatin activity 6.00 µM CNE2 Homo sapiens
STATTIC MTT Influence on cisplatin activity 8.00 µM CNE2 Homo sapiens
STATTIC MTT Influence on cisplatin activity 2.00 µM HONE1 Homo sapiens
STATTIC MTT Influence on cisplatin activity 4.00 µM HONE1 Homo sapiens
STATTIC MTT Influence on cisplatin activity 6.00 µM HONE1 Homo sapiens
STATTIC MTT Influence on cisplatin activity 8.00 µM HONE1 Homo sapiens
STATTIC MTT Influence on cisplatin activity 2.00 µM C666-1 Homo sapiens
STATTIC MTT Influence on cisplatin activity 4.00 µM C666-1 Homo sapiens
STATTIC MTT Influence on cisplatin activity 6.00 µM C666-1 Homo sapiens
STATTIC MTT Influence on cisplatin activity 8.00 µM C666-1 Homo sapiens
STATTIC Western Blot Influence on protein activity in presence of cisplatin 5.00 µM CNE1 Homo sapiens
STATTIC Western Blot Influence on protein activity in presence of cisplatin 5.00 µM CNE2 Homo sapiens
STATTIC Western Blot Influence on protein activity in presence of cisplatin 5.00 µM HONE1 Homo sapiens
STATTIC Western Blot Influence on protein activity in presence of cisplatin 5.00 µM C666-1 Homo sapiens
STATTIC Western Blot Influence on protein activity in presence of cisplatin 5.00 µM CNE1 Homo sapiens
STATTIC Western Blot Influence on protein activity in presence of cisplatin 5.00 µM CNE2 Homo sapiens
STATTIC Western Blot Influence on protein activity in presence of cisplatin 5.00 µM HONE1 Homo sapiens
STATTIC Western Blot Influence on protein activity in presence of cisplatin 5.00 µM C666-1 Homo sapiens
STATTIC Western Blot Influence on protein activity in presence of cisplatin 5.00 µM CNE1 Homo sapiens
STATTIC Western Blot Influence on protein activity in presence of cisplatin 5.00 µM CNE2 Homo sapiens
STATTIC Western Blot Influence on protein activity in presence of cisplatin 5.00 µM HONE1 Homo sapiens
STATTIC Western Blot Influence on protein activity in presence of cisplatin 5.00 µM C666-1 Homo sapiens
STATTIC Western Blot Influence on protein activity in presence of cisplatin 5.00 µM CNE1 Homo sapiens
STATTIC Western Blot Influence on protein activity in presence of cisplatin 5.00 µM CNE2 Homo sapiens
STATTIC Western Blot Influence on protein activity in presence of cisplatin 5.00 µM HONE1 Homo sapiens
STATTIC Western Blot Influence on protein activity in presence of cisplatin 5.00 µM C666-1 Homo sapiens
STATTIC Western Blot Influence on protein activity in presence of cisplatin 5.00 µM CNE1 Homo sapiens
STATTIC Western Blot Influence on protein activity in presence of cisplatin 5.00 µM CNE2 Homo sapiens
STATTIC Western Blot Influence on protein activity in presence of cisplatin 5.00 µM HONE1 Homo sapiens
STATTIC Western Blot Influence on protein activity in presence of cisplatin 5.00 µM C666-1 Homo sapiens
STATTIC MTT Influence on viability in radiotherapy 1.00 µM CNE2 Homo sapiens
STATTIC MTT Influence on viability in radiotherapy 2.00 µM CNE2 Homo sapiens
STATTIC MTT Influence on viability in radiotherapy 1.00 µM HONE1 Homo sapiens
STATTIC MTT Influence on viability in radiotherapy 2.00 µM HONE1 Homo sapiens
STATTIC MTT Influence on viability in radiotherapy 1.00 µM C666-1 Homo sapiens
STATTIC MTT Influence on viability in radiotherapy 2.00 µM C666-1 Homo sapiens
STATTIC Colony Formation Influence on viability in radiotherapy 0.01 µM CNE2 Homo sapiens
STATTIC PI staining Influence on viability in radiotherapy 5.00 µM CNE2 Homo sapiens
STATTIC PI staining Influence on viability in radiotherapy 5.00 µM HONE1 Homo sapiens
STATTIC Western Blot Influence on protein activity in radiotherapy 5.00 µM CNE2 Homo sapiens
STATTIC Western Blot Influence on protein activity in radiotherapy 5.00 µM HONE1 Homo sapiens
STATTIC Western Blot Influence on protein activity in radiotherapy 5.00 µM C666-1 Homo sapiens
STATTIC Western Blot Influence on protein activity in radiotherapy 5.00 µM CNE2 Homo sapiens
STATTIC Western Blot Influence on protein activity in radiotherapy 5.00 µM HONE1 Homo sapiens
STATTIC Western Blot Influence on protein activity in radiotherapy 5.00 µM C666-1 Homo sapiens
STATTIC Western Blot Influence on protein activity in radiotherapy 5.00 µM CNE2 Homo sapiens
STATTIC Western Blot Influence on protein activity in radiotherapy 5.00 µM HONE1 Homo sapiens
STATTIC Western Blot Influence on protein activity in radiotherapy 5.00 µM C666-1 Homo sapiens
STATTIC Fluorescence polarization Interaction with STAT-SH2 domain 50.00 µM STAT3
STATTIC Fluorescence polarization Interaction with STAT-SH2 domain 100.00 µM STAT3
STATTIC Fluorescence polarization Interaction with STAT-SH2 domain 150.00 µM STAT3
STATTIC Fluorescence polarization Interaction with STAT-SH2 domain 200.00 µM STAT3
STATTIC Fluorescence polarization Interaction with STAT-SH2 domain 250.00 µM STAT3
STATTIC Fluorescence polarization Interaction with STAT-SH2 domain 50.00 µM STAT1
STATTIC Fluorescence polarization Interaction with STAT-SH2 domain 100.00 µM STAT1
STATTIC Fluorescence polarization Interaction with STAT-SH2 domain 150.00 µM STAT1
STATTIC Fluorescence polarization Interaction with STAT-SH2 domain 200.00 µM STAT1
STATTIC Fluorescence polarization Interaction with STAT-SH2 domain 250.00 µM STAT1
STATTIC Fluorescence polarization Interaction with STAT-SH2 domain 50.00 µM STAT5B
STATTIC Fluorescence polarization Interaction with STAT-SH2 domain 100.00 µM STAT5B
STATTIC Fluorescence polarization Interaction with STAT-SH2 domain 150.00 µM STAT5B
STATTIC Fluorescence polarization Interaction with STAT-SH2 domain 200.00 µM STAT5B
STATTIC Fluorescence polarization Interaction with STAT-SH2 domain 250.00 µM STAT5B
STATTIC EMSA Influence on protein-protein and protein-DNA interaction in presence of EGF 100.00 µM STAT3:STAT3
STATTIC EMSA Influence on protein-protein and protein-DNA interaction in presence of EGF 200.00 µM STAT3:STAT3
STATTIC EMSA Influence on protein-protein and protein-DNA interaction in presence of EGF 100.00 µM STAT3:STAT1
STATTIC EMSA Influence on protein-protein and protein-DNA interaction in presence of EGF 200.00 µM STAT3:STAT1
STATTIC EMSA Influence on protein-protein and protein-DNA interaction in presence of EGF 100.00 µM STAT1:STAT1
STATTIC EMSA Influence on protein-protein and protein-DNA interaction in presence of EGF 200.00 µM STAT1:STAT1
STATTIC Western Blot Influence on protein activity in presence of IL-6 5.00 µM HepG2 Homo sapiens p-STAT3
STATTIC Western Blot Influence on protein activity in presence of IL-6 10.00 µM HepG2 Homo sapiens p-STAT3
STATTIC Western Blot Influence on protein activity in presence of IL-6 20.00 µM HepG2 Homo sapiens p-STAT3
STATTIC Western Blot Influence on protein activity in presence of IL-6 5.00 µM HepG2 Homo sapiens STAT3
STATTIC Western Blot Influence on protein activity in presence of IL-6 10.00 µM HepG2 Homo sapiens STAT3
STATTIC Western Blot Influence on protein activity in presence of IL-6 20.00 µM HepG2 Homo sapiens STAT3
STATTIC Western Blot Influence on protein activity in presence of IL-6 5.00 µM HepG2 Homo sapiens
STATTIC Western Blot Influence on protein activity in presence of IL-6 10.00 µM HepG2 Homo sapiens
STATTIC Western Blot Influence on protein activity in presence of IL-6 20.00 µM HepG2 Homo sapiens
STATTIC Western Blot Influence on protein activity in presence of IFNγ 5.00 µM HepG2 Homo sapiens p-STAT1
STATTIC Western Blot Influence on protein activity in presence of IFNγ 10.00 µM HepG2 Homo sapiens p-STAT1
STATTIC Western Blot Influence on protein activity in presence of IFNγ 20.00 µM HepG2 Homo sapiens p-STAT1
STATTIC Western Blot Influence on protein activity in presence of IFNγ 5.00 µM HepG2 Homo sapiens STAT1
STATTIC Western Blot Influence on protein activity in presence of IFNγ 10.00 µM HepG2 Homo sapiens STAT1
STATTIC Western Blot Influence on protein activity in presence of IFNγ 20.00 µM HepG2 Homo sapiens STAT1
STATTIC Western Blot Influence on protein activity in presence of IFNγ 5.00 µM HepG2 Homo sapiens
STATTIC Western Blot Influence on protein activity in presence of IFNγ 10.00 µM HepG2 Homo sapiens
STATTIC Western Blot Influence on protein activity in presence of IFNγ 20.00 µM HepG2 Homo sapiens
STATTIC EMSA Influence on protein-DNA interaction in presence of IL-6 20.00 µM HepG2 Homo sapiens STAT3:STAT3
STATTIC EMSA Influence on protein-DNA interaction in presence of IL-6 5.00 µM HepG2 Homo sapiens STAT3:STAT3
STATTIC EMSA Influence on protein-DNA interaction in presence of IL-6 1.00 µM HepG2 Homo sapiens STAT3:STAT3
STATTIC EMSA Influence on protein-DNA interaction in presence of IFNγ 20.00 µM HepG2 Homo sapiens STAT1:STAT1
STATTIC EMSA Influence on protein-DNA interaction in presence of IFNγ 5.00 µM HepG2 Homo sapiens STAT1:STAT1
STATTIC EMSA Influence on protein-DNA interaction in presence of IFNγ 1.00 µM HepG2 Homo sapiens STAT1:STAT1
STATTIC Immunofluorescce Influence on protein translocation 20.00 µM HepG2 Homo sapiens STAT1
STATTIC Immunofluorescce Influence on protein translocation 20.00 µM HepG2 Homo sapiens STAT3
STATTIC Western Blot Influence on apoptosis 10.00 µM MDA-MB-231 Homo sapiens p-STAT3
STATTIC Western Blot Influence on apoptosis 20.00 µM MDA-MB-231 Homo sapiens p-STAT3
STATTIC Western Blot Influence on apoptosis 10.00 µM MDA-MB-435S Homo sapiens p-STAT3
STATTIC Western Blot Influence on apoptosis 20.00 µM MDA-MB-435S Homo sapiens p-STAT3
STATTIC Western Blot Influence on apoptosis 10.00 µM MDA-MB-231 Homo sapiens STAT3
STATTIC Western Blot Influence on apoptosis 20.00 µM MDA-MB-231 Homo sapiens STAT3
STATTIC Western Blot Influence on apoptosis 10.00 µM MDA-MB-435S Homo sapiens STAT3
STATTIC Western Blot Influence on apoptosis 20.00 µM MDA-MB-435S Homo sapiens STAT3
STATTIC Western Blot Influence on apoptosis 10.00 µM MDA-MB-231 Homo sapiens
STATTIC Western Blot Influence on apoptosis 20.00 µM MDA-MB-231 Homo sapiens
STATTIC Western Blot Influence on apoptosis 10.00 µM MDA-MB-435S Homo sapiens
STATTIC Western Blot Influence on apoptosis 20.00 µM MDA-MB-435S Homo sapiens
STATTIC Western Blot Influence on apoptosis 10.00 µM MDA-MB-231 Homo sapiens
STATTIC Western Blot Influence on apoptosis 20.00 µM MDA-MB-231 Homo sapiens
STATTIC Western Blot Influence on apoptosis 10.00 µM MDA-MB-435S Homo sapiens
STATTIC Western Blot Influence on apoptosis 20.00 µM MDA-MB-435S Homo sapiens
STATTIC Western Blot Influence on apoptosis 10.00 µM MDA-MB-231 Homo sapiens
STATTIC Western Blot Influence on apoptosis 20.00 µM MDA-MB-231 Homo sapiens
STATTIC Western Blot Influence on apoptosis 10.00 µM MDA-MB-435S Homo sapiens
STATTIC Western Blot Influence on apoptosis 20.00 µM MDA-MB-435S Homo sapiens
STATTIC Western Blot Influence on apoptosis 10.00 µM MDA-MB-231 Homo sapiens
STATTIC Western Blot Influence on apoptosis 20.00 µM MDA-MB-231 Homo sapiens
STATTIC Western Blot Influence on apoptosis 10.00 µM MDA-MB-435S Homo sapiens
STATTIC Western Blot Influence on apoptosis 20.00 µM MDA-MB-435S Homo sapiens
STATTIC Western Blot Influence on apoptosis 10.00 µM MDA-MB-231 Homo sapiens
STATTIC Western Blot Influence on apoptosis 20.00 µM MDA-MB-231 Homo sapiens
STATTIC Western Blot Influence on apoptosis 10.00 µM MDA-MB-435S Homo sapiens
STATTIC Western Blot Influence on apoptosis 20.00 µM MDA-MB-435S Homo sapiens
STATTIC Western Blot Influence on apoptosis 10.00 µM MDA-MB-231 Homo sapiens
STATTIC Western Blot Influence on apoptosis 20.00 µM MDA-MB-231 Homo sapiens
STATTIC Western Blot Influence on apoptosis 10.00 µM MDA-MB-435S Homo sapiens
STATTIC Western Blot Influence on apoptosis 20.00 µM MDA-MB-435S Homo sapiens
STATTIC Western Blot Influence on apoptosis 10.00 µM MDA-MB-231 Homo sapiens
STATTIC Western Blot Influence on apoptosis 20.00 µM MDA-MB-231 Homo sapiens
STATTIC Western Blot Influence on apoptosis 10.00 µM MDA-MB-435S Homo sapiens
STATTIC Western Blot Influence on apoptosis 20.00 µM MDA-MB-435S Homo sapiens
STATTIC Western Blot Influence on apoptosis 10.00 µM MDA-MB-231 Homo sapiens
STATTIC Western Blot Influence on apoptosis 20.00 µM MDA-MB-231 Homo sapiens
STATTIC Western Blot Influence on apoptosis 10.00 µM MDA-MB-435S Homo sapiens
STATTIC Western Blot Influence on apoptosis 20.00 µM MDA-MB-435S Homo sapiens
STATTIC Western Blot Influence on apoptosis 10.00 µM MDA-MB-231 Homo sapiens
STATTIC Western Blot Influence on apoptosis 20.00 µM MDA-MB-231 Homo sapiens
STATTIC Western Blot Influence on apoptosis 10.00 µM MDA-MB-435S Homo sapiens
STATTIC Western Blot Influence on apoptosis 20.00 µM MDA-MB-435S Homo sapiens
STATTIC Western Blot Influence on apoptosis 10.00 µM MDA-MB-231 Homo sapiens
STATTIC Western Blot Influence on apoptosis 20.00 µM MDA-MB-231 Homo sapiens
STATTIC Western Blot Influence on apoptosis 10.00 µM MDA-MB-435S Homo sapiens
STATTIC Western Blot Influence on apoptosis 20.00 µM MDA-MB-435S Homo sapiens
STATTIC Western Blot Influence on apoptosis 10.00 µM MDA-MB-231 Homo sapiens
STATTIC Western Blot Influence on apoptosis 20.00 µM MDA-MB-231 Homo sapiens
STATTIC Western Blot Influence on apoptosis 10.00 µM MDA-MB-435S Homo sapiens
STATTIC Western Blot Influence on apoptosis 20.00 µM MDA-MB-435S Homo sapiens
STATTIC Western Blot Influence on apoptosis 10.00 µM MDA-MB-231 Homo sapiens
STATTIC Western Blot Influence on apoptosis 20.00 µM MDA-MB-231 Homo sapiens
STATTIC Western Blot Influence on apoptosis 10.00 µM MDA-MB-435S Homo sapiens
STATTIC Western Blot Influence on apoptosis 20.00 µM MDA-MB-435S Homo sapiens
STATTIC Flow cytometry Influence on apoptosis 10.00 µM MDA-MB-231 Homo sapiens
STATTIC Flow cytometry Influence on apoptosis 10.00 µM MDA-MB-435S Homo sapiens
STATTIC Flow cytometry Influence on apoptosis 10.00 µM MDA-MB-435 Homo sapiens
STATTIC TUNEL Influence on apoptosis 10.00 µM MDA-MB-435S Homo sapiens
STATTIC TUNEL Influence on apoptosis 10.00 µM MDA-MB-435 Homo sapiens
STATTIC Western Blot Influence on protein activity in precence of IFNα 10.00 µM HMEC Homo sapiens p-STAT1
STATTIC Western Blot Influence on protein activity in precence of IFNα 5.00 µM HMEC Homo sapiens p-STAT1
STATTIC Western Blot Influence on protein activity in precence of IFNα 2.50 µM HMEC Homo sapiens p-STAT1
STATTIC Western Blot Influence on protein activity in precence of IFNα 10.00 µM HMEC Homo sapiens STAT1
STATTIC Western Blot Influence on protein activity in precence of IFNα 5.00 µM HMEC Homo sapiens STAT1
STATTIC Western Blot Influence on protein activity in precence of IFNα 2.50 µM HMEC Homo sapiens STAT1
STATTIC Western Blot Influence on protein activity in precence of IFNα 10.00 µM HMEC Homo sapiens p-STAT2
STATTIC Western Blot Influence on protein activity in precence of IFNα 5.00 µM HMEC Homo sapiens p-STAT2
STATTIC Western Blot Influence on protein activity in precence of IFNα 2.50 µM HMEC Homo sapiens p-STAT2
STATTIC Western Blot Influence on protein activity in precence of IFNα 10.00 µM HMEC Homo sapiens STAT2
STATTIC Western Blot Influence on protein activity in precence of IFNα 5.00 µM HMEC Homo sapiens STAT2
STATTIC Western Blot Influence on protein activity in precence of IFNα 2.50 µM HMEC Homo sapiens STAT2
STATTIC Western Blot Influence on protein activity in precence of IFNα 10.00 µM HMEC Homo sapiens p-STAT3
STATTIC Western Blot Influence on protein activity in precence of IFNα 5.00 µM HMEC Homo sapiens p-STAT3
STATTIC Western Blot Influence on protein activity in precence of IFNα 2.50 µM HMEC Homo sapiens p-STAT3
STATTIC Western Blot Influence on protein activity in precence of IFNα 10.00 µM HMEC Homo sapiens STAT3
STATTIC Western Blot Influence on protein activity in precence of IFNα 5.00 µM HMEC Homo sapiens STAT3
STATTIC Western Blot Influence on protein activity in precence of IFNα 2.50 µM HMEC Homo sapiens STAT3
STATTIC Western Blot Influence on protein activity in precence of IFNα 10.00 µM HMEC Homo sapiens
STATTIC Western Blot Influence on protein activity in precence of IFNα 5.00 µM HMEC Homo sapiens
STATTIC Western Blot Influence on protein activity in precence of IFNα 2.50 µM HMEC Homo sapiens
STATTIC RT-qPCR Influence on gene expression in precence of IFNα 10.00 µM HMEC Homo sapiens
STATTIC RT-qPCR Influence on gene expression in precence of IFNα 5.00 µM HMEC Homo sapiens
STATTIC RT-qPCR Influence on gene expression in precence of IFNα 2.50 µM HMEC Homo sapiens
STATTIC RT-qPCR Influence on gene expression in precence of IFNα 10.00 µM HMEC Homo sapiens
STATTIC RT-qPCR Influence on gene expression in precence of IFNα 5.00 µM HMEC Homo sapiens
STATTIC RT-qPCR Influence on gene expression in precence of IFNα 2.50 µM HMEC Homo sapiens
STATTIC RT-qPCR Influence on gene expression in precence of IFNα 10.00 µM HMEC Homo sapiens
STATTIC RT-qPCR Influence on gene expression in precence of IFNα 5.00 µM HMEC Homo sapiens
STATTIC RT-qPCR Influence on gene expression in precence of IFNα 2.50 µM HMEC Homo sapiens
STATTIC RT-qPCR Influence on gene expression in precence of IFNα 10.00 µM HMEC Homo sapiens
STATTIC RT-qPCR Influence on gene expression in precence of IFNα 5.00 µM HMEC Homo sapiens
STATTIC RT-qPCR Influence on gene expression in precence of IFNα 2.50 µM HMEC Homo sapiens
STATTIC RT-qPCR Influence on gene expression in precence of IFNγLPS 10.00 µM HMEC Homo sapiens
STATTIC RT-qPCR Influence on gene expression in precence of IFNγLPS 5.00 µM HMEC Homo sapiens
STATTIC RT-qPCR Influence on gene expression in precence of IFNγLPS 2.50 µM HMEC Homo sapiens
STATTIC RT-qPCR Influence on gene expression in precence of IFNγLPS 10.00 µM HMEC Homo sapiens
STATTIC RT-qPCR Influence on gene expression in precence of IFNγLPS 5.00 µM HMEC Homo sapiens
STATTIC RT-qPCR Influence on gene expression in precence of IFNγLPS 2.50 µM HMEC Homo sapiens
STATTIC RT-qPCR Influence on gene expression in precence of IFNγLPS 10.00 µM HMEC Homo sapiens
STATTIC RT-qPCR Influence on gene expression in precence of IFNγLPS 5.00 µM HMEC Homo sapiens
STATTIC RT-qPCR Influence on gene expression in precence of IFNγLPS 2.50 µM HMEC Homo sapiens
STATTIC RT-qPCR Influence on gene expression in precence of IFNγLPS 10.00 µM HMEC Homo sapiens
STATTIC RT-qPCR Influence on gene expression in precence of IFNγLPS 5.00 µM HMEC Homo sapiens
STATTIC RT-qPCR Influence on gene expression in precence of IFNγLPS 2.50 µM HMEC Homo sapiens
STATTIC RT-qPCR Influence on gene expression in precence of IFNγLPS 10.00 µM HMEC Homo sapiens
STATTIC RT-qPCR Influence on gene expression in precence of IFNγLPS 5.00 µM HMEC Homo sapiens
STATTIC RT-qPCR Influence on gene expression in precence of IFNγLPS 2.50 µM HMEC Homo sapiens
STATTIC RT-qPCR Influence on gene expression in precence of IFNγLPS 10.00 µM HMEC Homo sapiens
STATTIC RT-qPCR Influence on gene expression in precence of IFNγLPS 5.00 µM HMEC Homo sapiens
STATTIC RT-qPCR Influence on gene expression in precence of IFNγLPS 2.50 µM HMEC Homo sapiens
STATTIC RT-qPCR Influence on gene expression in precence of IFNγLPS 10.00 µM HMEC Homo sapiens
STATTIC RT-qPCR Influence on gene expression in precence of IFNγLPS 5.00 µM HMEC Homo sapiens
STATTIC RT-qPCR Influence on gene expression in precence of IFNγLPS 2.50 µM HMEC Homo sapiens
STATTIC Wound healing assay Influence on cell motility in precence of IFNγLPS 10.00 µM HMEC Homo sapiens
STATTIC Adhesion assay Influence on cell motility in precence of IFNγLPS 1.00 µM HUVECS Homo sapiens
STATTIC Adhesion assay Influence on cell motility in precence of IFNγLPS 5.00 µM HUVECS Homo sapiens
STATTIC Constriction assay Influence on artery contractility in precence of IFNγLPS and noradrenaline 1.00 nM mesenteric artery Mus musculus