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Experiments

Compound Investigated event Experiment type Concentration Cell line Organism Animal model Stat protein Details
STATTIC Interaction with STAT-SH2 domain Fluorescence polarization 100.00 µM STAT1
STATTIC Interaction with STAT-SH2 domain Fluorescence polarization 150.00 µM STAT1
STATTIC Interaction with STAT-SH2 domain Fluorescence polarization 200.00 µM STAT1
STATTIC Interaction with STAT-SH2 domain Fluorescence polarization 250.00 µM STAT1
STATTIC Interaction with STAT-SH2 domain Fluorescence polarization 50.00 µM STAT5B
STATTIC Interaction with STAT-SH2 domain Fluorescence polarization 100.00 µM STAT5B
STATTIC Interaction with STAT-SH2 domain Fluorescence polarization 150.00 µM STAT5B
STATTIC Interaction with STAT-SH2 domain Fluorescence polarization 200.00 µM STAT5B
STATTIC Interaction with STAT-SH2 domain Fluorescence polarization 250.00 µM STAT5B
STATTIC Influence on protein-protein and protein-DNA interaction in presence of EGF EMSA 100.00 µM STAT3:STAT3
STATTIC Influence on protein-protein and protein-DNA interaction in presence of EGF EMSA 200.00 µM STAT3:STAT3
STATTIC Influence on protein-protein and protein-DNA interaction in presence of EGF EMSA 100.00 µM STAT3:STAT1
STATTIC Influence on protein-protein and protein-DNA interaction in presence of EGF EMSA 200.00 µM STAT3:STAT1
STATTIC Influence on protein-protein and protein-DNA interaction in presence of EGF EMSA 100.00 µM STAT1:STAT1
STATTIC Influence on protein-protein and protein-DNA interaction in presence of EGF EMSA 200.00 µM STAT1:STAT1
STATTIC Influence on protein activity in presence of IL-6 Western Blot 5.00 µM HepG2 Homo sapiens p-STAT3
STATTIC Influence on protein activity in presence of IL-6 Western Blot 10.00 µM HepG2 Homo sapiens p-STAT3
STATTIC Influence on protein activity in presence of IL-6 Western Blot 20.00 µM HepG2 Homo sapiens p-STAT3
STATTIC Influence on protein activity in presence of IL-6 Western Blot 5.00 µM HepG2 Homo sapiens STAT3
STATTIC Influence on protein activity in presence of IL-6 Western Blot 10.00 µM HepG2 Homo sapiens STAT3
STATTIC Influence on protein activity in presence of IL-6 Western Blot 20.00 µM HepG2 Homo sapiens STAT3
STATTIC Influence on protein activity in presence of IL-6 Western Blot 5.00 µM HepG2 Homo sapiens
STATTIC Influence on protein activity in presence of IL-6 Western Blot 10.00 µM HepG2 Homo sapiens
STATTIC Influence on protein activity in presence of IL-6 Western Blot 20.00 µM HepG2 Homo sapiens
STATTIC Influence on protein activity in presence of IFNγ Western Blot 5.00 µM HepG2 Homo sapiens p-STAT1
STATTIC Influence on protein activity in presence of IFNγ Western Blot 10.00 µM HepG2 Homo sapiens p-STAT1
STATTIC Influence on protein activity in presence of IFNγ Western Blot 20.00 µM HepG2 Homo sapiens p-STAT1
STATTIC Influence on protein activity in presence of IFNγ Western Blot 5.00 µM HepG2 Homo sapiens STAT1
STATTIC Influence on protein activity in presence of IFNγ Western Blot 10.00 µM HepG2 Homo sapiens STAT1
STATTIC Influence on protein activity in presence of IFNγ Western Blot 20.00 µM HepG2 Homo sapiens STAT1
STATTIC Influence on protein activity in presence of IFNγ Western Blot 5.00 µM HepG2 Homo sapiens
STATTIC Influence on protein activity in presence of IFNγ Western Blot 10.00 µM HepG2 Homo sapiens
STATTIC Influence on protein activity in presence of IFNγ Western Blot 20.00 µM HepG2 Homo sapiens
STATTIC Influence on protein-DNA interaction in presence of IL-6 EMSA 20.00 µM HepG2 Homo sapiens STAT3:STAT3
STATTIC Influence on protein-DNA interaction in presence of IL-6 EMSA 5.00 µM HepG2 Homo sapiens STAT3:STAT3
STATTIC Influence on protein-DNA interaction in presence of IL-6 EMSA 1.00 µM HepG2 Homo sapiens STAT3:STAT3
STATTIC Influence on protein-DNA interaction in presence of IFNγ EMSA 20.00 µM HepG2 Homo sapiens STAT1:STAT1
STATTIC Influence on protein-DNA interaction in presence of IFNγ EMSA 5.00 µM HepG2 Homo sapiens STAT1:STAT1
STATTIC Influence on protein-DNA interaction in presence of IFNγ EMSA 1.00 µM HepG2 Homo sapiens STAT1:STAT1
STATTIC Influence on protein translocation Immunofluorescce 20.00 µM HepG2 Homo sapiens STAT1
STATTIC Influence on protein translocation Immunofluorescce 20.00 µM HepG2 Homo sapiens STAT3
STATTIC Influence on apoptosis Western Blot 10.00 µM MDA-MB-231 Homo sapiens p-STAT3
STATTIC Influence on apoptosis Western Blot 20.00 µM MDA-MB-231 Homo sapiens p-STAT3
STATTIC Influence on apoptosis Western Blot 10.00 µM MDA-MB-435S Homo sapiens p-STAT3
STATTIC Influence on apoptosis Western Blot 20.00 µM MDA-MB-435S Homo sapiens p-STAT3
STATTIC Influence on apoptosis Western Blot 10.00 µM MDA-MB-231 Homo sapiens STAT3
STATTIC Influence on apoptosis Western Blot 20.00 µM MDA-MB-231 Homo sapiens STAT3
STATTIC Influence on apoptosis Western Blot 10.00 µM MDA-MB-435S Homo sapiens STAT3
STATTIC Influence on apoptosis Western Blot 20.00 µM MDA-MB-435S Homo sapiens STAT3
STATTIC Influence on apoptosis Western Blot 10.00 µM MDA-MB-231 Homo sapiens