| Oleanolic Acid |
Influence on protein activity |
Western Blot |
10.00 µM |
3T3-L1 |
Homo sapiens |
|
|
|
| Oleanolic Acid |
Influence on protein activity |
Western Blot |
25.00 µM |
3T3-L1 |
Homo sapiens |
|
|
|
| Oleanolic Acid |
Influence on protein activity |
Western Blot |
1.00 µM |
3T3-L1 |
Homo sapiens |
|
|
|
| Oleanolic Acid |
Influence on protein activity |
Western Blot |
5.00 µM |
3T3-L1 |
Homo sapiens |
|
|
|
| Oleanolic Acid |
Influence on protein activity |
Western Blot |
10.00 µM |
3T3-L1 |
Homo sapiens |
|
|
|
| Oleanolic Acid |
Influence on protein activity |
Western Blot |
25.00 µM |
3T3-L1 |
Homo sapiens |
|
|
|
| Paclitaxel |
Influence on protein activity |
Western Blot |
2.00 µM |
NRK-49F |
Homo sapiens |
|
p-STAT3 |
|
| Paclitaxel |
Influence on protein activity |
Western Blot |
4.00 µM |
NRK-49F |
Homo sapiens |
|
p-STAT3 |
|
| Paclitaxel |
Influence on protein activity |
Western Blot |
2.00 µM |
NRK-49F |
Homo sapiens |
|
STAT3 |
|
| Paclitaxel |
Influence on protein activity |
Western Blot |
4.00 µM |
NRK-49F |
Homo sapiens |
|
STAT3 |
|
| Paclitaxel |
Influence on protein activity |
Western Blot |
4.00 µM |
NRK-49F |
Homo sapiens |
|
|
|
| Paclitaxel |
Influence on protein activity |
Western Blot |
4.00 µM |
NRK-49F |
Homo sapiens |
|
|
|
| Paclitaxel |
Influence on protein activity |
Western Blot |
4.00 µM |
NRK-49F |
Homo sapiens |
|
|
|
| Paclitaxel |
Influence on protein activity |
Western Blot |
4.00 µM |
NRK-49F |
Homo sapiens |
|
|
|
| Paclitaxel |
Influence on protein activity- translocation |
Immunoprecipitation |
4.00 µM |
NRK-49F |
Homo sapiens |
|
p-STAT3/STAT3 |
|
| Paclitaxel |
Influence on protein activity- translocation |
Immunoprecipitation |
4.00 µM |
NRK-49F |
Homo sapiens |
|
STAT3/tubulin |
|
| Paclitaxel |
Influence on protein activity- translocation |
Western Blot |
4.00 µM |
NRK-49F |
Homo sapiens |
|
STAT3 (cytoplasm) |
|
| Paclitaxel |
Influence on protein activity- translocation |
Western Blot |
4.00 µM |
NRK-49F |
Homo sapiens |
|
STAT3 (nucleus) |
|
| Paclitaxel |
Influence on protein activity- translocation |
Western Blot |
4.00 µM |
NRK-49F |
Homo sapiens |
|
|
|
| Paclitaxel |
Influence on protein activity- translocation |
Western Blot |
4.00 µM |
NRK-49F |
Homo sapiens |
|
|
|
| Paclitaxel |
Influence on tubulointerstitial fibrosis |
HE staining |
0.30 mg/kg |
kidney tissue |
Mus musculus |
C57BL/6 (UUO) |
|
|
| Paclitaxel |
Influence on tubulointerstitial fibrosis |
Masson’s trichrome-staining |
0.30 mg/kg |
kidney tissue |
Mus musculus |
C57BL/6 (UUO) |
|
|
| Paclitaxel |
Influence on tubulointerstitial fibrosis |
Immunohistochemistry |
0.30 mg/kg |
kidney tissue |
Mus musculus |
C57BL/6 (UUO) |
p-STAT3 |
|
| Paclitaxel |
Influence on tubulointerstitial fibrosis |
Immunohistochemistry |
0.30 mg/kg |
kidney tissue |
Mus musculus |
C57BL/6 (UUO) |
|
|
| Paclitaxel |
Influence on tubulointerstitial fibrosis |
Immunohistochemistry |
0.30 mg/kg |
kidney tissue |
Mus musculus |
C57BL/6 (UUO) |
|
|
| Paclitaxel |
Influence on tubulointerstitial fibrosis |
Immunohistochemistry |
0.30 mg/kg |
kidney tissue |
Mus musculus |
C57BL/6 (UUO) |
|
|
| Paclitaxel |
Influence on inflammation- macrophage and neutrophil infiltration |
Immunohistochemistry |
0.30 mg/kg |
kidney tissue |
Mus musculus |
C57BL/6 (UUO) |
|
|
| Paclitaxel |
Influence on gene expression |
RT-qPCR |
0.30 mg/kg |
kidney tissue |
Mus musculus |
C57BL/6 (UUO) |
|
|
| Paclitaxel |
Influence on gene expression |
RT-qPCR |
0.30 mg/kg |
kidney tissue |
Mus musculus |
C57BL/6 (UUO) |
|
|
| Paclitaxel |
Influence on gene expression |
RT-qPCR |
0.30 mg/kg |
kidney tissue |
Mus musculus |
C57BL/6 (UUO) |
|
|
| Paclitaxel |
Influence on gene expression |
ELISA |
0.30 mg/kg |
kidney tissue |
Mus musculus |
C57BL/6 (UUO) |
|
|
| Paclitaxel |
Influence on gene expression |
ELISA |
0.30 mg/kg |
kidney tissue |
Mus musculus |
C57BL/6 (UUO) |
|
|
| Paclitaxel |
Influence on gene expression |
ELISA |
0.30 mg/kg |
kidney tissue |
Mus musculus |
C57BL/6 (UUO) |
|
|
| Pimozide |
Influence on proteins |
Western Blot |
5.00 µM |
Ba/f3 FLT3 ITD |
Homo sapiens |
|
p-STAT5 |
|
| Pimozide |
Influence on proteins |
Western Blot |
5.00 µM |
Ba/f3 FLT3 ITD |
Homo sapiens |
|
STAT5 |
|
| Pimozide |
Influence on proteins |
Western Blot |
5.00 µM |
Ba/f3 FLT3 ITD |
Homo sapiens |
|
|
|
| Pimozide |
Influence on proteins |
Western Blot |
5.00 µM |
Ba/f3 FLT3 ITD |
Homo sapiens |
|
|
|
| Pimozide |
Influence on cell viability |
ATP-dependent luminescence assay |
1.00 µM |
Ba/f3 FLT3 ITD |
Homo sapiens |
|
|
|
| Pimozide |
Influence on cell viability |
ATP-dependent luminescence assay |
3.00 µM |
Ba/f3 FLT3 ITD |
Homo sapiens |
|
|
|
| Pimozide |
Influence on cell viability |
ATP-dependent luminescence assay |
5.00 µM |
Ba/f3 FLT3 ITD |
Homo sapiens |
|
|
|
| Pimozide |
Influence on cell viability |
ATP-dependent luminescence assay |
7.50 µM |
Ba/f3 FLT3 ITD |
Homo sapiens |
|
|
|
| Pimozide |
Influence on cell viability |
ATP-dependent luminescence assay |
10.00 µM |
Ba/f3 FLT3 ITD |
Homo sapiens |
|
|
|
| Pimozide |
Influence on cell viability |
ATP-dependent luminescence assay |
1.00 µM |
MV411 |
Homo sapiens |
|
|
|
| Pimozide |
Influence on cell viability |
ATP-dependent luminescence assay |
3.00 µM |
MV411 |
Homo sapiens |
|
|
|
| Pimozide |
Influence on cell viability |
ATP-dependent luminescence assay |
5.00 µM |
MV411 |
Homo sapiens |
|
|
|
| Pimozide |
Influence on cell viability |
ATP-dependent luminescence assay |
7.50 µM |
MV411 |
Homo sapiens |
|
|
|
| Pimozide |
Influence on cell viability |
ATP-dependent luminescence assay |
10.00 µM |
MV411 |
Homo sapiens |
|
|
|
| Pimozide |
Influence on proteins in presece of PKC412 |
Western Blot |
5.00 µM |
Ba/f3 FLT3 ITD |
Homo sapiens |
|
p-STAT5 |
|
| Pimozide |
Influence on proteins in presece of PKC412 |
Western Blot |
5.00 µM |
MV411 |
Homo sapiens |
|
p-STAT5 |
|
| Pimozide |
Influence on proteins in presece of PKC412 |
Western Blot |
5.00 µM |
Ba/f3 FLT3 ITD |
Homo sapiens |
|
STAT5 |
|
