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Experiments

Compound Investigated event Experiment type Concentration Cell line Organism Animal model Stat protein Details
3,3 diindolylmethane Influence on cell viability in presence of PDGF Trypan blue dye exclusion assay 5.00 µM HUVECS Homo sapiens
3,3 diindolylmethane Influence on cell viability in presence of PDGF Trypan blue dye exclusion assay 10.00 µM HUVECS Homo sapiens
3,3 diindolylmethane Influence on cell viability in presence of PDGF Trypan blue dye exclusion assay 25.00 µM HUVECS Homo sapiens
3,3 diindolylmethane Influence on cell viability in presence of PDGF Trypan blue dye exclusion assay 50.00 µM HUVECS Homo sapiens
3,3 diindolylmethane Influence on cell cycle in presence of PDGF Flow cytometry 25.00 µM VSMC Homo sapiens
3,3 diindolylmethane Influence on cell cycle in presence of PDGF Western Blot 25.00 µM VSMC Homo sapiens
3,3 diindolylmethane Influence on cell cycle in presence of PDGF Western Blot 25.00 µM VSMC Homo sapiens
3,3 diindolylmethane Influence on cell cycle in presence of PDGF Western Blot 25.00 µM VSMC Homo sapiens
3,3 diindolylmethane Influence on cell cycle in presence of PDGF Western Blot 25.00 µM VSMC Homo sapiens
3,3 diindolylmethane Influence on cell cycle in presence of PDGF Western Blot 25.00 µM VSMC Homo sapiens
3,3 diindolylmethane Influence on cell motility in presence on PDGF Cell Migration Assay 25.00 µM VSMC Homo sapiens
3,3 diindolylmethane Influence on protein activity in presence of PDGF Western Blot 25.00 µM VSMC Homo sapiens
3,3 diindolylmethane Influence on protein activity in presence of PDGF Western Blot 25.00 µM VSMC Homo sapiens
3,3 diindolylmethane Influence on protein activity in presence of PDGF Western Blot 25.00 µM VSMC Homo sapiens
3,3 diindolylmethane Influence on protein activity in presence of PDGF Western Blot 25.00 µM VSMC Homo sapiens
3,3 diindolylmethane Influence on protein activity in presence of PDGF Western Blot 25.00 µM VSMC Homo sapiens
3,3 diindolylmethane Influence on protein activity in presence of PDGF Western Blot 25.00 µM VSMC Homo sapiens
3,3 diindolylmethane Influence on protein activity in presence of PDGF Western Blot 25.00 µM VSMC Homo sapiens
3,3 diindolylmethane Influence on protein activity in presence of PDGF Western Blot 25.00 µM VSMC Homo sapiens
3,3 diindolylmethane Influence on protein activity in presence of PDGF Western Blot 25.00 µM VSMC Homo sapiens
3,3 diindolylmethane Influence on protein activity in presence of PDGF Western Blot 25.00 µM VSMC Homo sapiens
3,3 diindolylmethane Influence on protein activity in presence of PDGF Western Blot 25.00 µM VSMC Homo sapiens
3,3 diindolylmethane Influence on protein activity in presence of PDGF Western Blot 25.00 µM VSMC Homo sapiens
3,3 diindolylmethane Influence on protein activity in presence of PDGF Western Blot 25.00 µM VSMC Homo sapiens p-STAT3
3,3 diindolylmethane Influence on protein activity in presence of PDGF Western Blot 25.00 µM VSMC Homo sapiens STAT3
3,3 diindolylmethane Influence on protein activity in tissue Immunohistochemistry 150.00 mg/kg carotid artery tissue Mus musculus c57BL/6
3,3 diindolylmethane Influence on protein activity in tissue Immunofluorescence 150.00 mg/kg carotid artery tissue Mus musculus c57BL/6
3,3 diindolylmethane Influence on reendothelialization Immunohistochemical staining 150.00 mg/kg carotid artery tissue Mus musculus c57BL/6
3,3 diindolylmethane Influence on inflammation in tissue Immunohistochemical staining 150.00 mg/kg carotid artery tissue Mus musculus c57BL/6
3,3 diindolylmethane Influence on apoptosis in tissue TUNEL 150.00 mg/kg carotid artery tissue Mus musculus
5,15-DPP Influence on protein-DNA interaction in presence of IL-6 DNA binding activity assay 10.00 µM MDA-MB-468 Homo sapiens STAT3
5,15-DPP Influence on protein-DNA interaction in presence of IL-6 DNA binding activity assay 20.00 µM MDA-MB-468 Homo sapiens STAT3
5,15-DPP Influence on protein-DNA interaction in presence of IL-6 DNA binding activity assay 50.00 µM MDA-MB-468 Homo sapiens STAT3
5,15-DPP Influence on protein-DNA interaction in presence of IL-6 DNA binding activity assay 10.00 µM MDA-MB-468 Homo sapiens STAT1
5,15-DPP Influence on protein-DNA interaction in presence of IL-6 DNA binding activity assay 20.00 µM MDA-MB-468 Homo sapiens STAT1
5,15-DPP Influence on protein-DNA interaction in presence of IL-6 DNA binding activity assay 50.00 µM MDA-MB-468 Homo sapiens STAT1
5,15-DPP Influence on protein-DNA interaction in presence of IL-6 DNA binding activity assay 10.00 µM MDA-MB-468 Homo sapiens STAT5A
5,15-DPP Influence on protein-DNA interaction in presence of IL-6 DNA binding activity assay 20.00 µM MDA-MB-468 Homo sapiens STAT5A
5,15-DPP Influence on protein-DNA interaction in presence of IL-6 DNA binding activity assay 50.00 µM MDA-MB-468 Homo sapiens STAT5A
5,15-DPP Influence on protein-DNA interaction in presence of IL-6 DNA binding activity assay 10.00 µM MDA-MB-468 Homo sapiens STAT5B
5,15-DPP Influence on protein-DNA interaction in presence of IL-6 DNA binding activity assay 20.00 µM MDA-MB-468 Homo sapiens STAT5B
5,15-DPP Influence on protein-DNA interaction in presence of IL-6 DNA binding activity assay 50.00 µM MDA-MB-468 Homo sapiens STAT5B
5,15-DPP Influence on protein activity FRET 10.00 µM HEK293 Homo sapiens
5,15-DPP Influence on protein activity FRET 20.00 µM HEK293 Homo sapiens
5,15-DPP Influence on protein activity FRET 50.00 µM HEK293 Homo sapiens
5,15-DPP Influence on protein activity Chromatin immunoprecipitation 10.00 µM MDA-MB-468 Homo sapiens
5,15-DPP Influence on protein activity Chromatin immunoprecipitation 20.00 µM MDA-MB-468 Homo sapiens
5,15-DPP Influence on protein activity Chromatin immunoprecipitation 50.00 µM MDA-MB-468 Homo sapiens
5,15-DPP Influence on protein activity Western Blot 10.00 µM MDA-MB-468 Homo sapiens p-STAT3(Y705)
5,15-DPP Influence on protein activity Western Blot 20.00 µM MDA-MB-468 Homo sapiens p-STAT3(Y705)