| Momelotinib (CYT387) |
Influence on surface protein |
Western Blot |
100.00 nM |
DC |
Mus musculus |
|
|
|
| Momelotinib (CYT387) |
Influence on surface protein |
RT-PCR |
100.00 nM |
DC |
Mus musculus |
|
|
|
| Momelotinib (CYT387) |
Influence on inflammatory Th2 cell response |
Flow cytometry |
100.00 nM |
DC |
Mus musculus |
|
|
|
| Momelotinib (CYT387) |
Influence on cytokine levels |
ELISA |
100.00 nM |
DC |
Mus musculus |
|
|
|
| Momelotinib (CYT387) |
Influence on cytokine levels |
ELISA |
100.00 nM |
DC |
Mus musculus |
|
|
|
| Momelotinib (CYT387) |
Influence on cytokine levels |
ELISA |
100.00 nM |
DC |
Mus musculus |
|
|
|
| Momelotinib (CYT387) |
Influence on Th2 response |
Histopathological staining |
30.00 mg/kg |
nasal mucosa |
Mus musculus |
AR |
|
|
| Momelotinib (CYT387) |
Influence on Th2 response |
Western Blot |
30.00 mg/kg |
nasal mucosa |
Mus musculus |
AR |
|
|
| Momelotinib (CYT387) |
Influence on Th2 response |
Western Blot |
30.00 mg/kg |
nasal mucosa |
Mus musculus |
AR |
|
|
| Momelotinib (CYT387) |
Influence on cytokine levels |
ELISA |
30.00 mg/kg |
nasal mucosa |
Mus musculus |
AR |
|
|
| Momelotinib (CYT387) |
Influence on cytokine levels |
ELISA |
30.00 mg/kg |
nasal mucosa |
Mus musculus |
AR |
|
|
| Momelotinib (CYT387) |
Influence on cytokine levels |
ELISA |
30.00 mg/kg |
nasal mucosa |
Mus musculus |
AR |
|
|
| Momelotinib (CYT387) |
Influence on cytokine levels |
ELISPOT |
30.00 mg/kg |
nasal mucosa |
Mus musculus |
AR |
|
|
| Momelotinib (CYT387) |
Influence on cytokine levels |
ELISPOT |
30.00 mg/kg |
nasal mucosa |
Mus musculus |
AR |
|
|
| E738 |
Influence on kinase activity |
Kinase activity assay |
10.40 nM |
|
Homo sapiens |
|
|
|
| E738 |
Influence on kinase activity |
Kinase activity assay |
74.10 nM |
|
Homo sapiens |
|
|
|
| E738 |
Influence on kinase activity |
Kinase activity assay |
0.70 nM |
|
Homo sapiens |
|
|
|
| E738 |
Influence on cell viability |
MTS |
0.10 µM |
Panc-1 |
Homo sapiens |
|
|
|
| E738 |
Influence on cell viability |
MTS |
0.50 µM |
Panc-1 |
Homo sapiens |
|
|
|
| E738 |
Influence on cell viability |
MTS |
2.50 µM |
Panc-1 |
Homo sapiens |
|
|
|
| E738 |
Influence on cell viability |
MTS |
5.00 µM |
Panc-1 |
Homo sapiens |
|
|
|
| E738 |
Influence on cell viability |
MTS |
10.00 µM |
Panc-1 |
Homo sapiens |
|
|
|
| E738 |
Influence on cell viability |
MTS |
0.10 µM |
MIA-PaCa2 |
Homo sapiens |
|
|
|
| E738 |
Influence on cell viability |
MTS |
0.50 µM |
MIA-PaCa2 |
Homo sapiens |
|
|
|
| E738 |
Influence on cell viability |
MTS |
2.50 µM |
MIA-PaCa2 |
Homo sapiens |
|
|
|
| E738 |
Influence on cell viability |
MTS |
5.00 µM |
MIA-PaCa2 |
Homo sapiens |
|
|
|
| E738 |
Influence on cell viability |
MTS |
10.00 µM |
MIA-PaCa2 |
Homo sapiens |
|
|
|
| E738 |
Influence on cell viability |
MTS |
0.10 µM |
BxPC3 |
Homo sapiens |
|
|
|
| E738 |
Influence on cell viability |
MTS |
0.50 µM |
BxPC3 |
Homo sapiens |
|
|
|
| E738 |
Influence on cell viability |
MTS |
2.50 µM |
BxPC3 |
Homo sapiens |
|
|
|
| E738 |
Influence on cell viability |
MTS |
5.00 µM |
BxPC3 |
Homo sapiens |
|
|
|
| E738 |
Influence on cell viability |
MTS |
10.00 µM |
BxPC3 |
Homo sapiens |
|
|
|
| E738 |
Influence on cell viability |
MTS |
0.10 µM |
AcPC1 |
Homo sapiens |
|
|
|
| E738 |
Influence on cell viability |
MTS |
0.50 µM |
AcPC1 |
Homo sapiens |
|
|
|
| E738 |
Influence on cell viability |
MTS |
2.50 µM |
AcPC1 |
Homo sapiens |
|
|
|
| E738 |
Influence on cell viability |
MTS |
5.00 µM |
AcPC1 |
Homo sapiens |
|
|
|
| E738 |
Influence on cell viability |
MTS |
10.00 µM |
AcPC1 |
Homo sapiens |
|
|
|
| E738 |
Influence on protein activity |
Western Blot |
5.00 µM |
Panc-1 |
Homo sapiens |
|
|
|
| E738 |
Influence on protein activity |
Western Blot |
5.00 µM |
MIA-PaCa2 |
Homo sapiens |
|
|
|
| E738 |
Influence on protein activity |
Western Blot |
5.00 µM |
BxPC3 |
Homo sapiens |
|
|
|
| E738 |
Influence on protein activity |
Western Blot |
5.00 µM |
AcPC1 |
Homo sapiens |
|
|
|
| E738 |
Influence on protein activity |
Western Blot |
5.00 µM |
Panc-1 |
Homo sapiens |
|
|
|
| E738 |
Influence on protein activity |
Western Blot |
5.00 µM |
MIA-PaCa2 |
Homo sapiens |
|
|
|
| E738 |
Influence on protein activity |
Western Blot |
5.00 µM |
BxPC3 |
Homo sapiens |
|
|
|
| E738 |
Influence on protein activity |
Western Blot |
5.00 µM |
AcPC1 |
Homo sapiens |
|
|
|
| E738 |
Influence on protein activity |
Western Blot |
5.00 µM |
Panc-1 |
Homo sapiens |
|
|
|
| E738 |
Influence on protein activity |
Western Blot |
5.00 µM |
MIA-PaCa2 |
Homo sapiens |
|
|
|
| E738 |
Influence on protein activity |
Western Blot |
5.00 µM |
BxPC3 |
Homo sapiens |
|
|
|
| E738 |
Influence on protein activity |
Western Blot |
5.00 µM |
AcPC1 |
Homo sapiens |
|
|
|
| E738 |
Influence on protein activity |
Western Blot |
5.00 µM |
Panc-1 |
Homo sapiens |
|
|
|
