Pimozide |
Western Blot |
Influence on proteins |
5.00 µM |
Ba/f3 FLT3 ITD |
Homo sapiens |
|
p-STAT5 |
|
Pimozide |
Western Blot |
Influence on proteins |
5.00 µM |
Ba/f3 FLT3 ITD |
Homo sapiens |
|
STAT5 |
|
Pimozide |
Western Blot |
Influence on proteins |
5.00 µM |
Ba/f3 FLT3 ITD |
Homo sapiens |
|
|
|
Pimozide |
Western Blot |
Influence on proteins |
5.00 µM |
Ba/f3 FLT3 ITD |
Homo sapiens |
|
|
|
Pimozide |
ATP-dependent luminescence assay |
Influence on cell viability |
1.00 µM |
Ba/f3 FLT3 ITD |
Homo sapiens |
|
|
|
Pimozide |
ATP-dependent luminescence assay |
Influence on cell viability |
3.00 µM |
Ba/f3 FLT3 ITD |
Homo sapiens |
|
|
|
Pimozide |
ATP-dependent luminescence assay |
Influence on cell viability |
5.00 µM |
Ba/f3 FLT3 ITD |
Homo sapiens |
|
|
|
Pimozide |
ATP-dependent luminescence assay |
Influence on cell viability |
7.50 µM |
Ba/f3 FLT3 ITD |
Homo sapiens |
|
|
|
Pimozide |
ATP-dependent luminescence assay |
Influence on cell viability |
10.00 µM |
Ba/f3 FLT3 ITD |
Homo sapiens |
|
|
|
Pimozide |
ATP-dependent luminescence assay |
Influence on cell viability |
1.00 µM |
MV411 |
Homo sapiens |
|
|
|
Pimozide |
ATP-dependent luminescence assay |
Influence on cell viability |
3.00 µM |
MV411 |
Homo sapiens |
|
|
|
Pimozide |
ATP-dependent luminescence assay |
Influence on cell viability |
5.00 µM |
MV411 |
Homo sapiens |
|
|
|
Pimozide |
ATP-dependent luminescence assay |
Influence on cell viability |
7.50 µM |
MV411 |
Homo sapiens |
|
|
|
Pimozide |
ATP-dependent luminescence assay |
Influence on cell viability |
10.00 µM |
MV411 |
Homo sapiens |
|
|
|
Pimozide |
Western Blot |
Influence on proteins in presece of PKC412 |
5.00 µM |
Ba/f3 FLT3 ITD |
Homo sapiens |
|
p-STAT5 |
|
Pimozide |
Western Blot |
Influence on proteins in presece of PKC412 |
5.00 µM |
MV411 |
Homo sapiens |
|
p-STAT5 |
|
Pimozide |
Western Blot |
Influence on proteins in presece of PKC412 |
5.00 µM |
Ba/f3 FLT3 ITD |
Homo sapiens |
|
STAT5 |
|
Pimozide |
Western Blot |
Influence on proteins in presece of PKC412 |
5.00 µM |
MV411 |
Homo sapiens |
|
STAT5 |
|
Pimozide |
ATP-dependent luminescence assay |
Influence on cell viability in presence of PKC412 |
5.00 µM |
Ba/f3 FLT3 ITD |
Homo sapiens |
|
|
|
Pimozide |
Flow cytometry- Annexin |
Influence on cell apoptosis in presence of PKC412 |
5.00 µM |
Ba/f3 FLT3 ITD |
Homo sapiens |
|
|
|
Pimozide |
Western Blot |
Influence on protein activity in presence of sunitinib |
5.00 µM |
Ba/f3 FLT3 ITD |
Homo sapiens |
|
p-STAT5 |
|
Pimozide |
Western Blot |
Influence on protein activity in presence of sunitinib |
5.00 µM |
Ba/f3 FLT3 ITD |
Homo sapiens |
|
STAT5 |
|
Pimozide |
ATP-dependent luminescence assay |
Influence on cell viability in presence of sunitinib |
5.00 µM |
Ba/f3 FLT3 ITD |
Homo sapiens |
|
|
|
Pimozide |
Flow cytometry- Annexin |
Influence on cell apoptosis in presence of sunitinib |
5.00 µM |
Ba/f3 FLT3 ITD |
Homo sapiens |
|
|
|
Pimozide |
Body weight |
Influence on tumor growth |
25.00 mg/kg |
Ba/f3 FLT3 ITD luc+ |
Mus musculus |
NCr nude mice |
|
|
Pimozide |
Average survival |
Influence on tumor growth |
25.00 mg/kg |
Ba/f3 FLT3 ITD luc+ |
Mus musculus |
NCr nude mice |
|
|
Pimozide |
Relative bioluminescence |
Influence on tumor growth |
25.00 mg/kg |
Ba/f3 FLT3 ITD luc+ |
Mus musculus |
NCr nude mice |
|
|
Pimozide |
Luciferase activity |
Influence on protein activity |
1.00 µM |
Reporter cell line |
Homo sapiens |
|
STAT1 luc |
|
Pimozide |
Luciferase activity |
Influence on protein activity |
2.50 µM |
Reporter cell line |
Homo sapiens |
|
STAT1 luc |
|
Pimozide |
Luciferase activity |
Influence on protein activity |
5.00 µM |
Reporter cell line |
Homo sapiens |
|
STAT1 luc |
|
Pimozide |
Luciferase activity |
Influence on protein activity |
7.50 µM |
Reporter cell line |
Homo sapiens |
|
STAT1 luc |
|
Pimozide |
Luciferase activity |
Influence on protein activity |
10.00 µM |
Reporter cell line |
Homo sapiens |
|
STAT1 luc |
|
Pimozide |
Luciferase activity |
Influence on protein activity |
1.00 µM |
Reporter cell line |
Homo sapiens |
|
STAT3 luc |
|
Pimozide |
Luciferase activity |
Influence on protein activity |
2.50 µM |
Reporter cell line |
Homo sapiens |
|
STAT3 luc |
|
Pimozide |
Luciferase activity |
Influence on protein activity |
5.00 µM |
Reporter cell line |
Homo sapiens |
|
STAT3 luc |
|
Pimozide |
Luciferase activity |
Influence on protein activity |
7.50 µM |
Reporter cell line |
Homo sapiens |
|
STAT3 luc |
|
Pimozide |
Luciferase activity |
Influence on protein activity |
10.00 µM |
Reporter cell line |
Homo sapiens |
|
STAT3 luc |
|
Pimozide |
Luciferase activity |
Influence on protein activity |
1.00 µM |
Reporter cell line |
Homo sapiens |
|
|
|
Pimozide |
Luciferase activity |
Influence on protein activity |
2.50 µM |
Reporter cell line |
Homo sapiens |
|
|
|
Pimozide |
Luciferase activity |
Influence on protein activity |
5.00 µM |
Reporter cell line |
Homo sapiens |
|
|
|
Pimozide |
Luciferase activity |
Influence on protein activity |
7.50 µM |
Reporter cell line |
Homo sapiens |
|
|
|
Pimozide |
Luciferase activity |
Influence on protein activity |
10.00 µM |
Reporter cell line |
Homo sapiens |
|
|
|
Pimozide |
RT-qPCR |
Influence on gene expression |
5.00 µM |
KU812 |
Homo sapiens |
|
|
|
Pimozide |
RT-qPCR |
Influence on gene expression |
5.00 µM |
KU812 |
Homo sapiens |
|
|
|
Pimozide |
RT-qPCR |
Influence on gene expression |
5.00 µM |
KU812 |
Homo sapiens |
|
|
|
Pimozide |
RT-qPCR |
Influence on gene expression |
5.00 µM |
KU812 |
Homo sapiens |
|
|
|
Pimozide |
RT-qPCR |
Influence on gene expression |
5.00 µM |
KU812 |
Homo sapiens |
|
|
|
Pimozide |
Western Blot |
Influence on protein activity |
1.00 µM |
KU812 |
Homo sapiens |
|
p-STAT5 |
|
Pimozide |
Western Blot |
Influence on protein activity |
2.50 µM |
KU812 |
Homo sapiens |
|
p-STAT5 |
|
Pimozide |
Western Blot |
Influence on protein activity |
5.00 µM |
KU812 |
Homo sapiens |
|
p-STAT5 |
|
Pimozide |
Western Blot |
Influence on protein activity |
7.50 µM |
KU812 |
Homo sapiens |
|
p-STAT5 |
|
Pimozide |
Western Blot |
Influence on protein activity |
10.00 µM |
KU812 |
Homo sapiens |
|
p-STAT5 |
|
Pimozide |
Western Blot |
Influence on protein activity |
1.00 µM |
KU812 |
Homo sapiens |
|
STAT5 |
|
Pimozide |
Western Blot |
Influence on protein activity |
2.50 µM |
KU812 |
Homo sapiens |
|
STAT5 |
|
Pimozide |
Western Blot |
Influence on protein activity |
5.00 µM |
KU812 |
Homo sapiens |
|
STAT5 |
|
Pimozide |
Western Blot |
Influence on protein activity |
7.50 µM |
KU812 |
Homo sapiens |
|
STAT5 |
|
Pimozide |
Western Blot |
Influence on protein activity |
10.00 µM |
KU812 |
Homo sapiens |
|
STAT5 |
|
Pimozide |
Western Blot |
Influence on protein activity |
10.00 µM |
K562 |
Homo sapiens |
|
p-STAT5 |
|
Pimozide |
Western Blot |
Influence on protein activity |
10.00 µM |
K562 |
Homo sapiens |
|
STAT5 |
|
Pimozide |
Western Blot |
Influence on protein activity |
10.00 µM |
K562 |
Homo sapiens |
|
|
|
Pimozide |
Western Blot |
Influence on protein activity |
10.00 µM |
K562 |
Homo sapiens |
|
|
|
Pimozide |
Western Blot |
Influence on protein activity |
10.00 µM |
KU812 |
Homo sapiens |
|
|
|
Pimozide |
Western Blot |
Influence on protein activity |
10.00 µM |
KU812 |
Homo sapiens |
|
|
|
Pimozide |
Western Blot |
Influence on protein activity |
10.00 µM |
K562 |
Homo sapiens |
|
|
|
Pimozide |
Western Blot |
Influence on protein activity |
10.00 µM |
K562 |
Homo sapiens |
|
|
|
Pimozide |
ATP-dependent luminescence assay |
Influence on cell viability |
1.00 µM |
KU812 |
Homo sapiens |
|
|
|
Pimozide |
ATP-dependent luminescence assay |
Influence on cell viability |
2.50 µM |
KU812 |
Homo sapiens |
|
|
|
Pimozide |
ATP-dependent luminescence assay |
Influence on cell viability |
5.00 µM |
KU812 |
Homo sapiens |
|
|
|
Pimozide |
ATP-dependent luminescence assay |
Influence on cell viability |
7.50 µM |
KU812 |
Homo sapiens |
|
|
|
Pimozide |
ATP-dependent luminescence assay |
Influence on cell viability |
10.00 µM |
KU812 |
Homo sapiens |
|
|
|
Pimozide |
ATP-dependent luminescence assay |
Influence on cell viability |
1.00 µM |
K562 |
Homo sapiens |
|
|
|
Pimozide |
ATP-dependent luminescence assay |
Influence on cell viability |
2.50 µM |
K562 |
Homo sapiens |
|
|
|
Pimozide |
ATP-dependent luminescence assay |
Influence on cell viability |
5.00 µM |
K562 |
Homo sapiens |
|
|
|
Pimozide |
ATP-dependent luminescence assay |
Influence on cell viability |
7.50 µM |
K562 |
Homo sapiens |
|
|
|
Pimozide |
ATP-dependent luminescence assay |
Influence on cell viability |
10.00 µM |
K562 |
Homo sapiens |
|
|
|
Pimozide |
ATP-dependent luminescence assay |
Influence on cell viability |
1.00 µM |
bone marrow mononuclear cells |
Homo sapiens (patient1) |
|
|
|
Pimozide |
ATP-dependent luminescence assay |
Influence on cell viability |
2.50 µM |
bone marrow mononuclear cells |
Homo sapiens (patient1) |
|
|
|
Pimozide |
ATP-dependent luminescence assay |
Influence on cell viability |
5.00 µM |
bone marrow mononuclear cells |
Homo sapiens (patient1) |
|
|
|
Pimozide |
ATP-dependent luminescence assay |
Influence on cell viability |
7.50 µM |
bone marrow mononuclear cells |
Homo sapiens (patient1) |
|
|
|
Pimozide |
ATP-dependent luminescence assay |
Influence on cell viability |
10.00 µM |
bone marrow mononuclear cells |
Homo sapiens (patient1) |
|
|
|
Pimozide |
ATP-dependent luminescence assay |
Influence on cell viability |
1.00 µM |
bone marrow mononuclear cells |
Homo sapiens (patient2) |
|
|
|
Pimozide |
ATP-dependent luminescence assay |
Influence on cell viability |
2.50 µM |
bone marrow mononuclear cells |
Homo sapiens (patient2) |
|
|
|
Pimozide |
ATP-dependent luminescence assay |
Influence on cell viability |
5.00 µM |
bone marrow mononuclear cells |
Homo sapiens (patient2) |
|
|
|
Pimozide |
ATP-dependent luminescence assay |
Influence on cell viability |
7.50 µM |
bone marrow mononuclear cells |
Homo sapiens (patient2) |
|
|
|
Pimozide |
ATP-dependent luminescence assay |
Influence on cell viability |
10.00 µM |
bone marrow mononuclear cells |
Homo sapiens (patient2) |
|
|
|
Pimozide |
Flow cytometry- Annexin |
Influence on cell viability |
5.00 µM |
KU812 |
Homo sapiens |
|
|
|
Pimozide |
Flow cytometry- Annexin |
Influence on cell viability |
1.00 µM |
peripheral blood mononuclear cells |
Homo sapiens (7 healthy patients) |
|
|
|
Pimozide |
Flow cytometry- Annexin |
Influence on cell viability |
2.50 µM |
peripheral blood mononuclear cells |
Homo sapiens (7 healthy patients) |
|
|
|
Pimozide |
Flow cytometry- Annexin |
Influence on cell viability |
5.00 µM |
peripheral blood mononuclear cells |
Homo sapiens (7 healthy patients) |
|
|
|
Pimozide |
Flow cytometry- Annexin |
Influence on cell viability |
7.50 µM |
peripheral blood mononuclear cells |
Homo sapiens (7 healthy patients) |
|
|
|
Pimozide |
Flow cytometry- Annexin |
Influence on cell viability |
10.00 µM |
peripheral blood mononuclear cells |
Homo sapiens (7 healthy patients) |
|
|
|
Pimozide |
Western Blot |
Influence on protein activity in presence of imatinib |
5.00 µM |
KU812 |
Homo sapiens |
|
p-STAT5 |
|
Pimozide |
Western Blot |
Influence on protein activity in presence of imatinib |
5.00 µM |
KU812 |
Homo sapiens |
|
STAT5 |
|
Pimozide |
ATP-dependent luminescence assay |
Influence on cell viability in presence of imatinib |
5.00 µM |
KU812 |
Homo sapiens |
|
|
|
Pimozide |
Flow cytometry- Annexin |
Influence on cell viability in presence of imatinib |
5.00 µM |
KU812 |
Homo sapiens |
|
|
|
Pimozide |
Western Blot |
Influence on protein activity in presence of nilotinib |
5.00 µM |
K562 |
Homo sapiens |
|
|
|
Pimozide |
Western Blot |
Influence on protein activity in presence of nilotinib |
5.00 µM |
K562 |
Homo sapiens |
|
|
|
Pimozide |
ATP-dependent luminescence assay |
Influence on cell viability in presence of nilotinib |
5.00 µM |
K562 |
Homo sapiens |
|
|
|
Pimozide |
RT-qPCR |
Influence on gene expression |
5.00 µM |
unmutated BCR/ABL |
Homo sapiens |
|
|
|
Pimozide |
RT-qPCR |
Influence on gene expression |
5.00 µM |
unmutated BCR/ABL |
Homo sapiens |
|
|
|
Pimozide |
RT-qPCR |
Influence on gene expression |
5.00 µM |
unmutated BCR/ABL |
Homo sapiens |
|
|
|
Pimozide |
RT-qPCR |
Influence on gene expression |
5.00 µM |
unmutated BCR/ABL |
Homo sapiens |
|
|
|
Pimozide |
Western Blot |
Influence on protein activity |
5.00 µM |
Kit225 |
Homo sapiens |
|
p-STAT5 |
|
Pimozide |
Western Blot |
Influence on protein activity |
7.50 µM |
Kit225 |
Homo sapiens |
|
p-STAT5 |
|
Pimozide |
Western Blot |
Influence on protein activity |
10.00 µM |
Kit225 |
Homo sapiens |
|
p-STAT5 |
|
Pimozide |
Western Blot |
Influence on protein activity |
15.00 µM |
Kit225 |
Homo sapiens |
|
p-STAT5 |
|
Pimozide |
Western Blot |
Influence on protein activity |
20.00 µM |
Kit225 |
Homo sapiens |
|
p-STAT5 |
|
Pimozide |
Western Blot |
Influence on protein activity |
5.00 µM |
Kit225 |
Homo sapiens |
|
STAT5 |
|
Pimozide |
Western Blot |
Influence on protein activity |
7.50 µM |
Kit225 |
Homo sapiens |
|
STAT5 |
|
Pimozide |
Western Blot |
Influence on protein activity |
10.00 µM |
Kit225 |
Homo sapiens |
|
STAT5 |
|
Pimozide |
Western Blot |
Influence on protein activity |
15.00 µM |
Kit225 |
Homo sapiens |
|
STAT5 |
|
Pimozide |
Western Blot |
Influence on protein activity |
20.00 µM |
Kit225 |
Homo sapiens |
|
STAT5 |
|
Pimozide |
Western Blot |
Influence on protein activity |
5.00 µM |
Kit225 |
Homo sapiens |
|
|
|
Pimozide |
Western Blot |
Influence on protein activity |
7.50 µM |
Kit225 |
Homo sapiens |
|
|
|
Pimozide |
Western Blot |
Influence on protein activity |
10.00 µM |
Kit225 |
Homo sapiens |
|
|
|
Pimozide |
Western Blot |
Influence on protein activity |
15.00 µM |
Kit225 |
Homo sapiens |
|
|
|
Pimozide |
Western Blot |
Influence on protein activity |
20.00 µM |
Kit225 |
Homo sapiens |
|
|
|
Pimozide |
Western Blot |
Influence on protein activity |
5.00 µM |
HuT102 |
Homo sapiens |
|
p-STAT5 |
|
Pimozide |
Western Blot |
Influence on protein activity |
7.50 µM |
HuT102 |
Homo sapiens |
|
p-STAT5 |
|
Pimozide |
Western Blot |
Influence on protein activity |
10.00 µM |
HuT102 |
Homo sapiens |
|
p-STAT5 |
|
Pimozide |
Western Blot |
Influence on protein activity |
15.00 µM |
HuT102 |
Homo sapiens |
|
p-STAT5 |
|
Pimozide |
Western Blot |
Influence on protein activity |
20.00 µM |
HuT102 |
Homo sapiens |
|
p-STAT5 |
|
Pimozide |
Western Blot |
Influence on protein activity |
5.00 µM |
HuT102 |
Homo sapiens |
|
STAT5 |
|
Pimozide |
Western Blot |
Influence on protein activity |
7.50 µM |
HuT102 |
Homo sapiens |
|
STAT5 |
|
Pimozide |
Western Blot |
Influence on protein activity |
10.00 µM |
HuT102 |
Homo sapiens |
|
STAT5 |
|
Pimozide |
Western Blot |
Influence on protein activity |
15.00 µM |
HuT102 |
Homo sapiens |
|
STAT5 |
|
Pimozide |
Western Blot |
Influence on protein activity |
20.00 µM |
HuT102 |
Homo sapiens |
|
STAT5 |
|
Pimozide |
Western Blot |
Influence on protein activity |
5.00 µM |
HuT102 |
Homo sapiens |
|
|
|
Pimozide |
Western Blot |
Influence on protein activity |
7.50 µM |
HuT102 |
Homo sapiens |
|
|
|
Pimozide |
Western Blot |
Influence on protein activity |
10.00 µM |
HuT102 |
Homo sapiens |
|
|
|
Pimozide |
Western Blot |
Influence on protein activity |
15.00 µM |
HuT102 |
Homo sapiens |
|
|
|
Pimozide |
Western Blot |
Influence on protein activity |
20.00 µM |
HuT102 |
Homo sapiens |
|
|
|
Pimozide |
Resazurin dye assay |
Influence on cell viability |
5.00 µM |
HuT102 |
Homo sapiens |
|
|
|
Pimozide |
Resazurin dye assay |
Influence on cell viability |
10.00 µM |
HuT102 |
Homo sapiens |
|
|
|
Pimozide |
Resazurin dye assay |
Influence on cell viability |
15.00 µM |
HuT102 |
Homo sapiens |
|
|
|
Pimozide |
Resazurin dye assay |
Influence on cell viability |
20.00 µM |
HuT102 |
Homo sapiens |
|
|
|
Pimozide |
Flow cytometry- Annexin |
Influence on apoptosis |
5.00 µM |
Kit225 |
Homo sapiens |
|
|
|
Pimozide |
Flow cytometry- Annexin |
Influence on apoptosis |
10.00 µM |
Kit225 |
Homo sapiens |
|
|
|
Pimozide |
Flow cytometry- Annexin |
Influence on apoptosis |
20.00 µM |
Kit225 |
Homo sapiens |
|
|
|
Pimozide |
Flow cytometry- Annexin |
Influence on apoptosis |
5.00 µM |
HuT102 |
Homo sapiens |
|
|
|
Pimozide |
Flow cytometry- Annexin |
Influence on apoptosis |
10.00 µM |
HuT102 |
Homo sapiens |
|
|
|
Pimozide |
Flow cytometry- Annexin |
Influence on apoptosis |
20.00 µM |
HuT102 |
Homo sapiens |
|
|
|
Pimozide |
Western Blot |
Influence on apoptosis |
7.50 µM |
Kit225 |
Homo sapiens |
|
|
|
Pimozide |
Western Blot |
Influence on apoptosis |
15.00 µM |
Kit225 |
Homo sapiens |
|
|
|
Pimozide |
Western Blot |
Influence on apoptosis |
7.50 µM |
HuT102 |
Homo sapiens |
|
|
|
Pimozide |
Western Blot |
Influence on apoptosis |
15.00 µM |
HuT102 |
Homo sapiens |
|
|
|
Pimozide |
Western Blot |
Influence on apoptosis |
7.50 µM |
Kit225 |
Homo sapiens |
|
|
|
Pimozide |
Western Blot |
Influence on apoptosis |
15.00 µM |
Kit225 |
Homo sapiens |
|
|
|
Pimozide |
Western Blot |
Influence on apoptosis |
7.50 µM |
HuT102 |
Homo sapiens |
|
|
|
Pimozide |
Western Blot |
Influence on apoptosis |
15.00 µM |
HuT102 |
Homo sapiens |
|
|
|
Pimozide |
Western Blot |
Influence on apoptosis |
5.00 µM |
Kit225 |
Homo sapiens |
|
|
|
Pimozide |
Western Blot |
Influence on apoptosis |
10.00 µM |
Kit225 |
Homo sapiens |
|
|
|
Pimozide |
Western Blot |
Influence on apoptosis |
20.00 µM |
Kit225 |
Homo sapiens |
|
|
|
Pimozide |
Western Blot |
Influence on apoptosis |
5.00 µM |
Kit225 |
Homo sapiens |
|
|
|
Pimozide |
Western Blot |
Influence on apoptosis |
10.00 µM |
Kit225 |
Homo sapiens |
|
|
|
Pimozide |
Western Blot |
Influence on apoptosis |
20.00 µM |
Kit225 |
Homo sapiens |
|
|
|
Pimozide |
Western Blot |
Influence on apoptosis |
5.00 µM |
Kit225 |
Homo sapiens |
|
|
|
Pimozide |
Western Blot |
Influence on apoptosis |
10.00 µM |
Kit225 |
Homo sapiens |
|
|
|
Pimozide |
Western Blot |
Influence on apoptosis |
20.00 µM |
Kit225 |
Homo sapiens |
|
|
|
Pimozide |
Western Blot |
Influence on apoptosis |
5.00 µM |
Kit225 |
Homo sapiens |
|
|
|
Pimozide |
Western Blot |
Influence on apoptosis |
10.00 µM |
Kit225 |
Homo sapiens |
|
|
|
Pimozide |
Western Blot |
Influence on apoptosis |
20.00 µM |
Kit225 |
Homo sapiens |
|
|
|
Pimozide |
Western Blot |
Influence on apoptosis |
5.00 µM |
HuT102 |
Homo sapiens |
|
|
|
Pimozide |
Western Blot |
Influence on apoptosis |
10.00 µM |
HuT102 |
Homo sapiens |
|
|
|
Pimozide |
Western Blot |
Influence on apoptosis |
20.00 µM |
HuT102 |
Homo sapiens |
|
|
|
Pimozide |
Western Blot |
Influence on apoptosis |
5.00 µM |
HuT102 |
Homo sapiens |
|
|
|
Pimozide |
Western Blot |
Influence on apoptosis |
10.00 µM |
HuT102 |
Homo sapiens |
|
|
|
Pimozide |
Western Blot |
Influence on apoptosis |
20.00 µM |
HuT102 |
Homo sapiens |
|
|
|
Pimozide |
Western Blot |
Influence on apoptosis |
5.00 µM |
HuT102 |
Homo sapiens |
|
|
|
Pimozide |
Western Blot |
Influence on apoptosis |
10.00 µM |
HuT102 |
Homo sapiens |
|
|
|
Pimozide |
Western Blot |
Influence on apoptosis |
20.00 µM |
HuT102 |
Homo sapiens |
|
|
|
Pimozide |
Western Blot |
Influence on apoptosis |
5.00 µM |
HuT102 |
Homo sapiens |
|
|
|
Pimozide |
Western Blot |
Influence on apoptosis |
10.00 µM |
HuT102 |
Homo sapiens |
|
|
|
Pimozide |
Western Blot |
Influence on apoptosis |
20.00 µM |
HuT102 |
Homo sapiens |
|
|
|
Pimozide |
Flow cytometry- Annexin |
Influence on TRAIL/DR4 dependent apoptosis |
5.00 µM |
Kit225 |
Homo sapiens |
|
|
|
Pimozide |
Flow cytometry- Annexin |
Influence on TRAIL/DR4 dependent apoptosis |
10.00 µM |
Kit225 |
Homo sapiens |
|
|
|
Pimozide |
Flow cytometry- Annexin |
Influence on TRAIL/DR4 dependent apoptosis |
20.00 µM |
Kit225 |
Homo sapiens |
|
|
|
Pimozide |
Flow cytometry- Annexin |
Influence on TRAIL/DR4 dependent apoptosis |
5.00 µM |
HuT102 |
Homo sapiens |
|
|
|
Pimozide |
Flow cytometry- Annexin |
Influence on TRAIL/DR4 dependent apoptosis |
10.00 µM |
HuT102 |
Homo sapiens |
|
|
|
Pimozide |
Flow cytometry- Annexin |
Influence on TRAIL/DR4 dependent apoptosis |
20.00 µM |
HuT102 |
Homo sapiens |
|
|
|
Pimozide |
Flow cytometry- Annexin |
Influence on TRAIL/DR4 dependent apoptosis |
5.00 µM |
Kit225 |
Homo sapiens |
|
|
|
Pimozide |
Flow cytometry- Annexin |
Influence on TRAIL/DR4 dependent apoptosis |
10.00 µM |
Kit225 |
Homo sapiens |
|
|
|
Pimozide |
Flow cytometry- Annexin |
Influence on TRAIL/DR4 dependent apoptosis |
20.00 µM |
Kit225 |
Homo sapiens |
|
|
|
Pimozide |
Flow cytometry- Annexin |
Influence on TRAIL/DR4 dependent apoptosis |
5.00 µM |
HuT102 |
Homo sapiens |
|
|
|
Pimozide |
Flow cytometry- Annexin |
Influence on TRAIL/DR4 dependent apoptosis |
10.00 µM |
HuT102 |
Homo sapiens |
|
|
|
Pimozide |
Flow cytometry- Annexin |
Influence on TRAIL/DR4 dependent apoptosis |
20.00 µM |
HuT102 |
Homo sapiens |
|
|
|
Pimozide |
Flow cytometry- Annexin |
Influence on TRAIL/DR4 dependent apoptosis |
5.00 µM |
Kit225 |
Homo sapiens |
|
|
|
Pimozide |
Flow cytometry- Annexin |
Influence on TRAIL/DR4 dependent apoptosis |
10.00 µM |
Kit225 |
Homo sapiens |
|
|
|
Pimozide |
Flow cytometry- Annexin |
Influence on TRAIL/DR4 dependent apoptosis |
20.00 µM |
Kit225 |
Homo sapiens |
|
|
|
Pimozide |
Flow cytometry- Annexin |
Influence on TRAIL/DR4 dependent apoptosis |
5.00 µM |
HuT102 |
Homo sapiens |
|
|
|
Pimozide |
Flow cytometry- Annexin |
Influence on TRAIL/DR4 dependent apoptosis |
10.00 µM |
HuT102 |
Homo sapiens |
|
|
|
Pimozide |
Flow cytometry- Annexin |
Influence on TRAIL/DR4 dependent apoptosis |
20.00 µM |
HuT102 |
Homo sapiens |
|
|
|
Pimozide |
Flow cytometry- Annexin |
Influence on TRAIL/DR4 dependent apoptosis |
5.00 µM |
Kit225 |
Homo sapiens |
|
|
|
Pimozide |
Flow cytometry- Annexin |
Influence on TRAIL/DR4 dependent apoptosis |
10.00 µM |
Kit225 |
Homo sapiens |
|
|
|
Pimozide |
Flow cytometry- Annexin |
Influence on TRAIL/DR4 dependent apoptosis |
20.00 µM |
Kit225 |
Homo sapiens |
|
|
|
Pimozide |
Flow cytometry- Annexin |
Influence on TRAIL/DR4 dependent apoptosis |
5.00 µM |
HuT102 |
Homo sapiens |
|
|
|
Pimozide |
Flow cytometry- Annexin |
Influence on TRAIL/DR4 dependent apoptosis |
10.00 µM |
HuT102 |
Homo sapiens |
|
|
|
Pimozide |
Flow cytometry- Annexin |
Influence on TRAIL/DR4 dependent apoptosis |
20.00 µM |
HuT102 |
Homo sapiens |
|
|
|
Pimozide |
Western Blot |
Influence on protein activity in patient tissue |
20.00 µM |
lymphoma cells |
Homo sapiens (patient 112) |
|
p-STAT5 |
|
Pimozide |
Western Blot |
Influence on protein activity in patient tissue |
20.00 µM |
lymphoma cells |
Homo sapiens (patient 112) |
|
STAT5 |
|
Pimozide |
Western Blot |
Influence on protein activity in patient tissue |
20.00 µM |
lymphoma cells |
Homo sapiens (patient 112) |
|
|
|
Pimozide |
Western Blot |
Influence on protein activity in patient tissue |
20.00 µM |
lymphoma cells |
Homo sapiens (patient 706) |
|
p-STAT5 |
|
Pimozide |
Western Blot |
Influence on protein activity in patient tissue |
20.00 µM |
lymphoma cells |
Homo sapiens (patient 706) |
|
STAT5 |
|
Pimozide |
Western Blot |
Influence on protein activity in patient tissue |
20.00 µM |
lymphoma cells |
Homo sapiens (patient 706) |
|
|
|
Pimozide |
Western Blot |
Influence on protein activity in patient tissue |
20.00 µM |
lymphoma cells |
Homo sapiens (patient 423) |
|
p-STAT5 |
|
Pimozide |
Western Blot |
Influence on protein activity in patient tissue |
20.00 µM |
lymphoma cells |
Homo sapiens (patient 423) |
|
STAT5 |
|
Pimozide |
Western Blot |
Influence on protein activity in patient tissue |
20.00 µM |
lymphoma cells |
Homo sapiens (patient 423) |
|
|
|
Pimozide |
Flow cytometry- Annexin |
Influence on apoptosis in patient tissue |
20.00 µM |
lymphoma cells |
Homo sapiens (patient 112) |
|
|
|
Pimozide |
Flow cytometry- Annexin |
Influence on apoptosis in patient tissue |
20.00 µM |
lymphoma cells |
Homo sapiens (patient 706) |
|
|
|
Pimozide |
Flow cytometry- Annexin |
Influence on apoptosis in patient tissue |
20.00 µM |
lymphoma cells |
Homo sapiens (patient 423) |
|
|
|