| Pimozide |
Influence on cell viability |
ATP-dependent luminescence assay |
7.50 µM |
Ba/f3 FLT3 ITD |
Homo sapiens |
|
|
|
| Pimozide |
Influence on cell viability |
ATP-dependent luminescence assay |
7.50 µM |
MV411 |
Homo sapiens |
|
|
|
| Pimozide |
Influence on protein activity |
Luciferase activity |
7.50 µM |
Reporter cell line |
Homo sapiens |
|
STAT1 luc |
|
| Pimozide |
Influence on protein activity |
Luciferase activity |
7.50 µM |
Reporter cell line |
Homo sapiens |
|
STAT3 luc |
|
| Pimozide |
Influence on protein activity |
Luciferase activity |
7.50 µM |
Reporter cell line |
Homo sapiens |
|
|
|
| Pimozide |
Influence on protein activity |
Western Blot |
7.50 µM |
KU812 |
Homo sapiens |
|
p-STAT5 |
|
| Pimozide |
Influence on protein activity |
Western Blot |
7.50 µM |
KU812 |
Homo sapiens |
|
STAT5 |
|
| Pimozide |
Influence on cell viability |
ATP-dependent luminescence assay |
7.50 µM |
KU812 |
Homo sapiens |
|
|
|
| Pimozide |
Influence on cell viability |
ATP-dependent luminescence assay |
7.50 µM |
K562 |
Homo sapiens |
|
|
|
| Pimozide |
Influence on cell viability |
ATP-dependent luminescence assay |
7.50 µM |
bone marrow mononuclear cells |
Homo sapiens (patient1) |
|
|
|
| Pimozide |
Influence on cell viability |
ATP-dependent luminescence assay |
7.50 µM |
bone marrow mononuclear cells |
Homo sapiens (patient2) |
|
|
|
| Pimozide |
Influence on cell viability |
Flow cytometry- Annexin |
7.50 µM |
peripheral blood mononuclear cells |
Homo sapiens (7 healthy patients) |
|
|
|
| Pimozide |
Influence on protein activity |
Western Blot |
7.50 µM |
Kit225 |
Homo sapiens |
|
p-STAT5 |
|
| Pimozide |
Influence on protein activity |
Western Blot |
7.50 µM |
Kit225 |
Homo sapiens |
|
STAT5 |
|
| Pimozide |
Influence on protein activity |
Western Blot |
7.50 µM |
Kit225 |
Homo sapiens |
|
|
|
| Pimozide |
Influence on protein activity |
Western Blot |
7.50 µM |
HuT102 |
Homo sapiens |
|
p-STAT5 |
|
| Pimozide |
Influence on protein activity |
Western Blot |
7.50 µM |
HuT102 |
Homo sapiens |
|
STAT5 |
|
| Pimozide |
Influence on protein activity |
Western Blot |
7.50 µM |
HuT102 |
Homo sapiens |
|
|
|
| Pimozide |
Influence on apoptosis |
Western Blot |
7.50 µM |
Kit225 |
Homo sapiens |
|
|
|
| Pimozide |
Influence on apoptosis |
Western Blot |
7.50 µM |
HuT102 |
Homo sapiens |
|
|
|
| Pimozide |
Influence on apoptosis |
Western Blot |
7.50 µM |
Kit225 |
Homo sapiens |
|
|
|
| Pimozide |
Influence on apoptosis |
Western Blot |
7.50 µM |
HuT102 |
Homo sapiens |
|
|
|
