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Experiments

Compound Investigated event Experiment type Concentration Cell line Organism Animal model Stat protein Details
Pimozide Influence on protein activity Luciferase activity 2.50 µM Reporter cell line Homo sapiens STAT1 luc
Pimozide Influence on protein activity Luciferase activity 2.50 µM Reporter cell line Homo sapiens STAT3 luc
Pimozide Influence on protein activity Luciferase activity 2.50 µM Reporter cell line Homo sapiens
Pimozide Influence on protein activity Western Blot 2.50 µM KU812 Homo sapiens p-STAT5
Pimozide Influence on protein activity Western Blot 2.50 µM KU812 Homo sapiens STAT5
Pimozide Influence on cell viability ATP-dependent luminescence assay 2.50 µM KU812 Homo sapiens
Pimozide Influence on cell viability ATP-dependent luminescence assay 2.50 µM K562 Homo sapiens
Pimozide Influence on cell viability ATP-dependent luminescence assay 2.50 µM bone marrow mononuclear cells Homo sapiens (patient1)
Pimozide Influence on cell viability ATP-dependent luminescence assay 2.50 µM bone marrow mononuclear cells Homo sapiens (patient2)
Pimozide Influence on cell viability Flow cytometry- Annexin 2.50 µM peripheral blood mononuclear cells Homo sapiens (7 healthy patients)