Pimozide |
Influence on protein activity |
Luciferase activity |
2.50 µM |
Reporter cell line |
Homo sapiens |
|
STAT1 luc |
|
Pimozide |
Influence on protein activity |
Luciferase activity |
2.50 µM |
Reporter cell line |
Homo sapiens |
|
STAT3 luc |
|
Pimozide |
Influence on protein activity |
Luciferase activity |
2.50 µM |
Reporter cell line |
Homo sapiens |
|
|
|
Pimozide |
Influence on protein activity |
Western Blot |
2.50 µM |
KU812 |
Homo sapiens |
|
p-STAT5 |
|
Pimozide |
Influence on protein activity |
Western Blot |
2.50 µM |
KU812 |
Homo sapiens |
|
STAT5 |
|
Pimozide |
Influence on cell viability |
ATP-dependent luminescence assay |
2.50 µM |
KU812 |
Homo sapiens |
|
|
|
Pimozide |
Influence on cell viability |
ATP-dependent luminescence assay |
2.50 µM |
K562 |
Homo sapiens |
|
|
|
Pimozide |
Influence on cell viability |
ATP-dependent luminescence assay |
2.50 µM |
bone marrow mononuclear cells |
Homo sapiens (patient1) |
|
|
|
Pimozide |
Influence on cell viability |
ATP-dependent luminescence assay |
2.50 µM |
bone marrow mononuclear cells |
Homo sapiens (patient2) |
|
|
|
Pimozide |
Influence on cell viability |
Flow cytometry- Annexin |
2.50 µM |
peripheral blood mononuclear cells |
Homo sapiens (7 healthy patients) |
|
|
|